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The map label for this gene is fmt

Identifier: 148267707

GI number: 148267707

Start: 1322879

End: 1323814

Strand: Direct

Name: fmt

Synonym: SaurJH9_1275

Alternate gene names: 148267707

Gene position: 1322879-1323814 (Clockwise)

Preceding gene: 148267706

Following gene: 148267708

Centisome position: 45.51

GC content: 34.94

Gene sequence:

>936_bases
ATGACTAAAATAATATTTATGGGTACACCAGACTTTTCAACAACTGTTTTAGAAATGCTTATTGCAGAACATGATGTCAT
TGCAGTCGTAACGCAACCAGATCGACCTGTTGGACGTAAACGTGTTATGACACCACCACCAGTTAAAAAAGTTGCAATGA
AATATGATTTACCTGTATATCAGCCTGAAAAATTAAGTGGATCAGAAGAATTAGAACAATTGCTTCAATTAGATGTAGAT
TTAATTGTAACTGCTGCTTTTGGACAATTATTACCTGAATCATTGTTGGCATTACCAAAACTTGGCGCAATTAATGTACA
TGCATCATTGTTACCAAAGTATAGAGGTGGTGCACCAATTCATCAGGCAATTATCGATGGTGAACAAGAAACCGGCATAA
CAATTATGTATATGGTTAAAAAATTAGATGCGGGTAATATTATTTCGCAACAAGCAATTAAAATAGAAGAAAATGATAAT
GTCGGTACGATGCATGATAAATTAAGTGTATTAGGGGCAGATTTATTAAAAGAAACTTTACCATCTATTATAGAGGGCAC
AAATGAAAGTGTACCTCAAGATGATACGCAAGCAACATTTGCTTCCAATATTCGACGCGAAGATGAGCGAATTAGCTGGA
ATAAACCAGGAAGACAAGTGTTTAATCAAATTCGTGGATTATCACCATGGCCAGTTGCTTATACAACTATGGATGACACT
AACTTGAAAATATACGATGCTGAACTCGTTGAGACTAATAAGATAAACGAGCCTGGAACCATTATAGAAACGACTAAAAA
AGCCATTATTGTTGCTACAAATGATAATGAAGCTGTTGCAATTAAAGATATGCAATTAGCTGGGAAAAAGAGAATGTTAG
CTGCCAATTATTTAAGTGGTGCGCAAAACACACTAGTAGGGAAGAAACTTATATGA

Upstream 100 bases:

>100_bases
AGAATGATTTTGCATATTATAGATCAAATGAACGGTATCCCTTTTACAGAACGTGCGGACCGTATTTTAACAGATAAAGA
AGTGGAGGCATATTTTATAA

Downstream 100 bases:

>100_bases
TCGAAAACGTGAGAAGTCTTGCTTTTGACACGATTCAAGATATATTAAATGAAGGTGCGTATAGTAACTTGCGTATCAAT
GAAGTGTTGTCAGAAAATGA

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVD
LIVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDN
VGTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDT
NLKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSGAQNTLVGKKLI

Sequences:

>Translated_311_residues
MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVD
LIVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDN
VGTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDT
NLKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSGAQNTLVGKKLI
>Mature_310_residues
TKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVDL
IVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDNV
GTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDTN
LKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSGAQNTLVGKKLI

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI21614513, Length=322, Percent_Identity=26.3975155279503, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI238814322, Length=316, Percent_Identity=25.6329113924051, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI164663775, Length=322, Percent_Identity=28.8819875776398, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1789683, Length=311, Percent_Identity=39.2282958199357, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1788589, Length=275, Percent_Identity=30.9090909090909, Blast_Score=152, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI133930964, Length=324, Percent_Identity=25.9259259259259, Blast_Score=101, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319458, Length=351, Percent_Identity=26.4957264957265, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550868, Length=303, Percent_Identity=28.7128712871287, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571984, Length=225, Percent_Identity=30.2222222222222, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24585660, Length=294, Percent_Identity=22.4489795918367, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_STAA1 (A7X1H4)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441796.1
- ProteinModelPortal:   A7X1H4
- SMR:   A7X1H4
- STRING:   A7X1H4
- EnsemblBacteria:   EBSTAT00000002969
- GeneID:   5561315
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1206
- eggNOG:   COG0223
- GeneTree:   EBGT00050000024715
- HOGENOM:   HBG571560
- OMA:   VVAYGAI
- ProtClustDB:   CLSK885209
- BioCyc:   SAUR418127:SAHV_1206-MONOMER
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 34226; Mature: 34095

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVY
CCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHEECCCCC
QPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPI
CCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCH
HQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDNVGTMHDKLSVLGADLLKETL
HHHHHCCCCCCCEEEEEEEHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
PSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCC
NLKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSG
CEEEEEEEEEECCCCCCCCCEEEECCCEEEEEECCCCEEEEECHHHCCCHHHHHHHHHCC
AQNTLVGKKLI
CHHHCCCCCCC
>Mature Secondary Structure 
TKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVY
CEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHEECCCCC
QPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPI
CCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCH
HQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDNVGTMHDKLSVLGADLLKETL
HHHHHCCCCCCCEEEEEEEHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
PSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCC
NLKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSG
CEEEEEEEEEECCCCCCCCCEEEECCCEEEEEECCCCEEEEECHHHCCCHHHHHHHHHCC
AQNTLVGKKLI
CHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA