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The map label for this gene is nhaA3 [H]

Identifier: 148243652

GI number: 148243652

Start: 18695

End: 20044

Strand: Reverse

Name: nhaA3 [H]

Synonym: Acry_3123

Alternate gene names: 148243652

Gene position: 20044-18695 (Counterclockwise)

Preceding gene: 148243654

Following gene: 148243651

Centisome position: 9.85

GC content: 60.3

Gene sequence:

>1350_bases
TTGATTACGGACCAGAACAGTAAACCGCAGCAAGGCGAACTGCCGACCACACACATCGACGCGCTGACCAACTCGTTTTC
GCAGTTCCTGCGCATCGAAGCCACGAGTGGTGCCGTTCTCCTGTTGGCCACCGTCGTTGCATTGACGCTTTCCAACTCAC
CCTGGTCCGATGGCTTCAGATCTCTTTGGGAGACACCAATCGGCATTCAGATCGGTGCGTTCCAGTTTTTGCGCTCGTTG
CGGGATCTGATCAACGACGGTCTGATGACGCTGTTCTTCTTCATCGTTGCGCTCGAGATCAAGCGCGAAGTGGTGCTTGG
TGAACTTCGGAACCCGCGCATGGTGGCTTTCTCGGTCGTAGCTGCGGCAGGAGGCATGCTTGTGCCCATGGGCTTGTATC
TGGCGCTGCAGCATGGCCAACCTGGGCAGCATGGTTGGGGCGTCGTGATGCCGACCGACACAGCTTTCGTCATCGGCTGC
CTGGCGCTCCTTGGTTCGCGTGTGCCTCCGGGCCTACGCGTCTTCCTGCTATCGCTTGCGGTCGTCGACGACCTTGCCGC
CATCCTCGTGGTCGCCGTCGGTTACAGTCGATCAATCGACTGGACTGCCCTTGCGCTCGGCGCCGTCGGACTGGTGATAA
TTCGGGGGATGGCATTACTCGGCGTTCGTAACATCCGCGTCTACTTTCTGGCTGGGGCAATAATCTGGCTCGCCGTCAAT
GCGTCCGGCATCCACGCGACGATTGTTGGTGTTATCCTCGGGCTCATGACACCGACGGCTGGCTGGGTGAGCGACCAGCG
TCTGGGGGAAATCTTGCGAAAGGTGCTCTCCTATCCCCCGGGAGATCATTGGAGTGGCGATACCGAGGATAACCGGGCGC
TGCAGGTTGCCGGTATCGCGGTGCGCGAGACGTTGTCGCCCGTCGAGAGGCTCGAGGCCATGCTCCATCCCTGGGTCGCC
TTCGGCGTTATGCCGCTTTTCGCGCTTGCAAACGCGGGGGTATCGATCACGATCAAGGGACTTATCAACCCAGTCTCGCT
GGCGGTGATGGCGGGCTTCGTCCTCGGCAAGCCGATCGGCGTCACAGCATTCGCATGGCTGGGGGTGCGCACGGGTGTCG
CCATTCGGCCGGCGGGGCTCACCTGGGGGGGACTTGTCGGTGGGGCTCTTCTTACCGGTATCGGATTCACCATGGCGCTG
TTTATCGCCGGCCAGGCATTTCAAGATGCCACCCTCAACGCAGCGAAACTGGGTATCCTTGCTGCCTCAGTCGTCTCTTC
TGTTGCTGGTCTCACGCTGCTGTGCATGTTCCCCAAGCGTGACCAAACGCTCGATGCCGATTTCCACTGA

Upstream 100 bases:

>100_bases
CAGCCTGATGCCGGGAAAAATTGGGCTTGCCGGGACGGGTAACCGCCTCGACACCCCGGGCGGGGTGGGTTTTCTCGAGA
TATAAGGGGAGATGGCCGAT

Downstream 100 bases:

>100_bases
ACCGGTCGTCGAGCGCCCGGGTCAGCGTCAGACGTTCAGCGCTGCGTCGGCCGTCAACGCCAAGGGCGGGTTCTGGTACT
GCACCTATGAGGGCGGCCTG

Product: Na+/H+ antiporter NhaA

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaA 3 [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSL
RDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVAFSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGC
LALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETLSPVERLEAMLHPWVA
FGVMPLFALANAGVSITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMAL
FIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCMFPKRDQTLDADFH

Sequences:

>Translated_449_residues
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSL
RDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVAFSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGC
LALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETLSPVERLEAMLHPWVA
FGVMPLFALANAGVSITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMAL
FIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCMFPKRDQTLDADFH
>Mature_449_residues
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSL
RDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVAFSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGC
LALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETLSPVERLEAMLHPWVA
FGVMPLFALANAGVSITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMAL
FIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCMFPKRDQTLDADFH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3004

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaA Na(+)/H(+) (TC 2.A.33) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1786201, Length=419, Percent_Identity=37.708830548926, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670 [H]

Pfam domain/function: PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 47421; Mature: 47421

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCHHHH
SLWETPIGIQIGAFQFLRSLRDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVAFSVV
HHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGCLALLGSRVPPGLRVFLLSLA
HHCCCHHHHHHHHHEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
VVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHH
VRETLSPVERLEAMLHPWVAFGVMPLFALANAGVSITIKGLINPVSLAVMAGFVLGKPIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHCCCCC
VTAFAWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGIL
HHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHH
AASVVSSVAGLTLLCMFPKRDQTLDADFH
HHHHHHHHHHHHEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCHHHH
SLWETPIGIQIGAFQFLRSLRDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVAFSVV
HHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGCLALLGSRVPPGLRVFLLSLA
HHCCCHHHHHHHHHEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
VVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHH
VRETLSPVERLEAMLHPWVAFGVMPLFALANAGVSITIKGLINPVSLAVMAGFVLGKPIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHCCCCC
VTAFAWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGIL
HHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHH
AASVVSSVAGLTLLCMFPKRDQTLDADFH
HHHHHHHHHHHHEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + 2 Proton [Periplasm] = Na (I) [Periplasm] + 2 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA