Click here to switch to the map view.

The map label for this gene is ygdL [H]

Identifier: 147675632

GI number: 147675632

Start: 2015316

End: 2016137

Strand: Reverse

Name: ygdL [H]

Synonym: VC0395_A1898

Alternate gene names: 147675632

Gene position: 2016137-2015316 (Counterclockwise)

Preceding gene: 147673142

Following gene: 147674303

Centisome position: 66.67

GC content: 49.27

Gene sequence:

>822_bases
GTGGTTATGCGTGAACTCGATACTCCTGCCTCCGACAGTTACAACCAACGTTTTGGTGGTACGCGCCGTTTGTATGGTTA
TGACGAAGTCGACATTTTACGTGCCGCGCACGTGTGTGTGATTGGGATTGGTGGTGTCGGTTCATGGGCGGTAGAAGCTC
TGGCGCGCACTGGTATTGGTGAGTTGACGTTGATTGATATGGATGATGTGTGTGTCACTAACATCAACCGTCAAATCCAT
GCCATGACCGGGACGATTGGCAAAAGCAAAATTGAAGTGATGGCGGAGCGCGTTAAGCTCATCAATCCAGAGTGCAAAGT
CAATTTGGTGGATGACTTCATCACGCCGGATAATCAACATCTTTATCTCAATAAATCCTTTGATTATGTGTTGGATGCGA
TTGACAGCTTGAAAGCCAAAGCTTCTCTTCTGGCTTACTGCCGCAGCAACAAAATCAAAGTGATTACAGTCGGAGGTGCG
GGCGGACAAACCGATCCAACGCAAATCACCGTGGCCGATTTGACCAAGACGATTCAAGATCCACTGGCGAAAAAGCTCAA
AGATCGCCTGCGTCAGCACCACAACTTCCCAACCAATCCAGCGCGTAAATTTGGGATTGATTGTGTTTTCTCGACCGAGC
AACTCAAATACCCACAAGCCGATGGTTCGGTATGCGCGACCAAATCAACCGCAGAAGGTCCAAAACGTATGGATTGCGCC
AGCGGATTTGGCGCTGCGACGGTAGTGACGGCGACGTTTGGTTTTGTCGCGGTGGCGCGCATCGTCGATAAATTGATTCA
AAAGCATAAAGTGAAGGCGTGA

Upstream 100 bases:

>100_bases
CAGCAATAGTTTTTCCTGATATTGTGCCGGTAGCAAACTGGACATTTTTGTGAAGAGTGCGTATAAATCGCACTCTTTAT
TTTTCAGCTAGAGTGGAAAT

Downstream 100 bases:

>100_bases
GGGCATGATGAGTCCATTTCCCGCTCATCCCTTTGGTGATGACATTAATGCACAAACCGTCTTAGAAACCATGCAAACAT
TGCGCGGTTGGGAAGATCGT

Product: HesA/MoeB/ThiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MVMRELDTPASDSYNQRFGGTRRLYGYDEVDILRAAHVCVIGIGGVGSWAVEALARTGIGELTLIDMDDVCVTNINRQIH
AMTGTIGKSKIEVMAERVKLINPECKVNLVDDFITPDNQHLYLNKSFDYVLDAIDSLKAKASLLAYCRSNKIKVITVGGA
GGQTDPTQITVADLTKTIQDPLAKKLKDRLRQHHNFPTNPARKFGIDCVFSTEQLKYPQADGSVCATKSTAEGPKRMDCA
SGFGAATVVTATFGFVAVARIVDKLIQKHKVKA

Sequences:

>Translated_273_residues
MVMRELDTPASDSYNQRFGGTRRLYGYDEVDILRAAHVCVIGIGGVGSWAVEALARTGIGELTLIDMDDVCVTNINRQIH
AMTGTIGKSKIEVMAERVKLINPECKVNLVDDFITPDNQHLYLNKSFDYVLDAIDSLKAKASLLAYCRSNKIKVITVGGA
GGQTDPTQITVADLTKTIQDPLAKKLKDRLRQHHNFPTNPARKFGIDCVFSTEQLKYPQADGSVCATKSTAEGPKRMDCA
SGFGAATVVTATFGFVAVARIVDKLIQKHKVKA
>Mature_273_residues
MVMRELDTPASDSYNQRFGGTRRLYGYDEVDILRAAHVCVIGIGGVGSWAVEALARTGIGELTLIDMDDVCVTNINRQIH
AMTGTIGKSKIEVMAERVKLINPECKVNLVDDFITPDNQHLYLNKSFDYVLDAIDSLKAKASLLAYCRSNKIKVITVGGA
GGQTDPTQITVADLTKTIQDPLAKKLKDRLRQHHNFPTNPARKFGIDCVFSTEQLKYPQADGSVCATKSTAEGPKRMDCA
SGFGAATVVTATFGFVAVARIVDKLIQKHKVKA

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=125, Percent_Identity=29.6, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789177, Length=258, Percent_Identity=65.5038759689922, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1787048, Length=154, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082356, Length=130, Percent_Identity=32.3076923076923, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=211, Percent_Identity=26.5402843601896, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322825, Length=164, Percent_Identity=31.0975609756098, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322639, Length=185, Percent_Identity=25.9459459459459, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24660640, Length=131, Percent_Identity=29.7709923664122, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29764; Mature: 29764

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMRELDTPASDSYNQRFGGTRRLYGYDEVDILRAAHVCVIGIGGVGSWAVEALARTGIG
CCCCCCCCCCCCCCHHHCCCCEEECCCCHHHHHHHCEEEEEEECCCHHHHHHHHHHCCCC
ELTLIDMDDVCVTNINRQIHAMTGTIGKSKIEVMAERVKLINPECKVNLVDDFITPDNQH
CEEEEECCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCE
LYLNKSFDYVLDAIDSLKAKASLLAYCRSNKIKVITVGGAGGQTDPTQITVADLTKTIQD
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHH
PLAKKLKDRLRQHHNFPTNPARKFGIDCVFSTEQLKYPQADGSVCATKSTAEGPKRMDCA
HHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEHHHHCCCCCCCCEEECCCCCCCCCHHHHH
SGFGAATVVTATFGFVAVARIVDKLIQKHKVKA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVMRELDTPASDSYNQRFGGTRRLYGYDEVDILRAAHVCVIGIGGVGSWAVEALARTGIG
CCCCCCCCCCCCCCHHHCCCCEEECCCCHHHHHHHCEEEEEEECCCHHHHHHHHHHCCCC
ELTLIDMDDVCVTNINRQIHAMTGTIGKSKIEVMAERVKLINPECKVNLVDDFITPDNQH
CEEEEECCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCE
LYLNKSFDYVLDAIDSLKAKASLLAYCRSNKIKVITVGGAGGQTDPTQITVADLTKTIQD
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHH
PLAKKLKDRLRQHHNFPTNPARKFGIDCVFSTEQLKYPQADGSVCATKSTAEGPKRMDCA
HHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEHHHHCCCCCCCCEEECCCCCCCCCHHHHH
SGFGAATVVTATFGFVAVARIVDKLIQKHKVKA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]