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The map label for this gene is mraY

Identifier: 147674771

GI number: 147674771

Start: 2126807

End: 2127889

Strand: Reverse

Name: mraY

Synonym: VC0395_A1982

Alternate gene names: 147674771

Gene position: 2127889-2126807 (Counterclockwise)

Preceding gene: 147673448

Following gene: 147674702

Centisome position: 70.37

GC content: 49.95

Gene sequence:

>1083_bases
ATGATTATTTGGCTTGCTGAACTGCTCCAGCCATATTTTTCGTTTTTCCGTCTGTTCGAATATCTCTCATTTCGCGCCAT
TGTCAGCATTCTGACTGCGCTTGGGATCTCGTTGTGGATGGGGCCGCGCATGATTAAGCGCCTACAAATGTTGCAGATTG
GGCAAGTAGTGCGTAATGAAGGGCCTGAATCTCACTTCAGTAAACGCGGTACTCCGACCATGGGTGGGGTGATGATCCTT
GCCGCGATCACCATCACTGTACTGCTGTGGGCCGACCTGACTAACCCTTATGTTTGGGCTGTGCTTGCGGTACTGCTCGG
TTACGGTGCGGTCGGTTTTGTCGATGATTACCGTAAAGTGGTGCGCAAAAATACCGATGGCTTGATCGCGCGCTGGAAAT
ACTTCTGGCAATCTGCGATTGCTTTAGTGGTTGCGTTTGCTCTGTATGCGCACGGCCAAGATACGGCGGCAACGCAGTTG
GTGGTCCCTTTCTTTAAAGATGTGATGCCACAGCTGGGCTTGATGTACATAGTGCTGACCTATTTCGTGATTGTTGGTAC
CAGTAATGCGGTGAACTTGACCGATGGTCTGGATGGCTTGGCGATCATGCCAACCGTATTGGTTGCAGCCGGATTTGCGG
CGATTGCATGGGCGACCGGTAACGTTAACTTCGCGAACTATCTGCATATCCCTTATATTCCTCACTCTTCTGAGTTGGTG
GTGGTGTGTACCGCGATGGTCGGTGCCGGTTTAGGCTTTTTATGGTTTAACACCTATCCAGCCCAAGTATTTATGGGCGA
CGTCGGCGCGTTGGCGTTGGGTGGTGCGTTAGGTACGATTGCGGTACTGGTTCGCCAAGAATTTGTGTTGGTGATCATGG
GCGGTGTATTCGTGATGGAAACCCTGTCAGTGATTTTGCAAGTTGGTTCTTACAAACTGCGTGGACAACGTATCTTCCGT
ATGGCACCGATTCACCATCACTACGAATTAAAAGGCTGGCCAGAACCACGTGTGATCGTGCGTTTTTGGGTCATCTCTAT
CGTTTTAGTATTGATTGGCTTAGCGACACTCAAAGTTCGTTAA

Upstream 100 bases:

>100_bases
ACATAGAACAACAACAGGGTCGTACTCAAGTATTGTTGGTGAAAGGTGCCAACAGTGCAGGGATGAGTAAAATTGCCGCT
GCTCTCAAGGAGAAATTTGC

Downstream 100 bases:

>100_bases
GTGGATTAAGGATGTCAATTTCAATGGACCGTTGGCAAGGCATACAACATGTGGTCGTCGTGGGGCTCGGGATTACCGGG
CTCTCTGTCGTTAATTATCT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNEGPESHFSKRGTPTMGGVMIL
AAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQL
VVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELV
VVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWVISIVLVLIGLATLKVR

Sequences:

>Translated_360_residues
MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNEGPESHFSKRGTPTMGGVMIL
AAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQL
VVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELV
VVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWVISIVLVLIGLATLKVR
>Mature_360_residues
MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNEGPESHFSKRGTPTMGGVMIL
AAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQL
VVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELV
VVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWVISIVLVLIGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=81.9444444444444, Blast_Score=586, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_VIBC3 (A5F5N2)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- STRING:   A5F5N2
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1982
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   VCHO345073:VC0395_A1982-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39806; Mature: 39806

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ad0f098)-; HASH(0x1b5fd590)-; HASH(0x1b616b1c)-; HASH(0x1b623cbc)-; HASH(0x1b5fd764)-; HASH(0x1b610694)-; HASH(0x1b6167d4)-; HASH(0x1b1c61d4)-; HASH(0x1b6106b8)-; HASH(0x1b610778)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNE
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGVMILAAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQLVVPFFKDVMPQLGLMYIVLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCCCHH
VVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVME
HHHHHHHHCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWVISIVLVLIGLATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNE
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGVMILAAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQLVVPFFKDVMPQLGLMYIVLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCCCHH
VVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVME
HHHHHHHHCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWVISIVLVLIGLATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA