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The map label for this gene is glmM

Identifier: 147674754

GI number: 147674754

Start: 171775

End: 173115

Strand: Direct

Name: glmM

Synonym: VC0395_A0168

Alternate gene names: 147674754

Gene position: 171775-173115 (Clockwise)

Preceding gene: 147674024

Following gene: 147675589

Centisome position: 5.68

GC content: 47.87

Gene sequence:

>1341_bases
ATGTCTGATAAGAGACGTTATTTTGGCACTGATGGGGTTCGTGGCAAAGTTGGCCAGTACCCAATTACTCCTGATTTTGT
ACTTAAGCTTGGCTGGGCGGCTGGACGTGTACTGGCAAAACAAGGCACGAGAAAAGTCATTATTGGTAAAGATACCCGTA
TTTCTGGCTATATGTTGGAGTCTGCACTGGAAGCTGGGCTTGCAGCGGCAGGATTAAAAGCGACCTTCACCGGACCAATG
CCAACGCCAGCTGTGGCCTATCTTACCCAAACGTTTCGTGCAGAAGCGGGGATTGTTATTTCTGCATCGCACAACCCTTA
CTACGATAACGGCATTAAGTTCTTCTCTTATGAAGGAGCCAAACTGCCGGATGACATTGAGTTAGCGATTGAAGCTGAGT
TAGATAAAGACATTGAATGTGTTGAATCGGCTGAGCTTGGTAAAGCTTCACGCATGGTGGATGCGGCGGGGCGTTACATC
GAATTTTGTAAAAGCACTTTCCCTTCAAAACTCAGTCTATCTGGTTTGAAGCTTGTTGTGGATTGTGCCAATGGTGCCAC
ATACCACATTGCGCCCAATGTTTTCCGTGAGTTGGGAGCGGAAGTCATTGCGATGGGCGTTGAGCCTAATGGTTTGAATA
TCAATGACCAAGTCGGTGCAACCGACGTTCGCGCACTGCAAAAACGCGTTGTTGAAGAGCATGCTCATCTTGGCCTTGCT
TTCGATGGTGACGGCGACCGCATCATCATGGTTGATCACCTAGGTAATAAAGTCGATGGTGACCAAATCGCTTACATTAT
TGCCCGTGATGCACTGCGCCGTGGCGAGCTCAAAGGTGGCGTTGTTGGGACATTGATGACGAACCTTGGCATGGAGAATG
GACTTAAACAGTTGGGCATTCCATTTGTACGCGCTGCGGTCGGTGATCGCTATGTTATGGAAAAACTTCTAGAGAAAGGC
TGGAAGATTGGTGCGGAAAATTCAGGTCACGTCATCTTACTCGATAAAGTGACTACGGGGGATGCGATTGTCGCTGGCCT
ACAAGTGCTGGCTTCAGTAGTGGGTAGTGAAATGACCCTGCATGAATTAGCGAAAGGTATGACGCTTTACCCACAAGTGT
TGGAGAATGTCCGTTTTGCAGGAGATAACAATCCACTTGAAGCGGATGCGGTGAAAGCGGCGGTATCTGAGGTTGAAGCT
GAGCTAGGTTCGAAAGGCCGTGTATTACTGCGCAAATCGGGTACAGAACCTCTGATCCGTGTGATGGTGGAAGGGGAAGA
TGAAACCTTAGTGAAGCAATCTGCATTAAAAATTGCTCAAGCTGTAAAAGATAACTGCTAA

Upstream 100 bases:

>100_bases
ATTATCCGTGTTCATGATGTAGAGCAGACCATTGATGCACTCAAAATGGTGCAGATGATGCATAACAATTTGTAAAAACA
ATAATGTAAAGGAAACACAA

Downstream 100 bases:

>100_bases
TTTGGGCGCTGGTTTCTACAATTCCTAGCTGATTGATTTCGCGCTAGGAATTGTAGAAATGCTCGAAAAAACGCTGTTGT
GCGAGTTTTTTGAGCGATCA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPM
PTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGAKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYI
EFCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKG
WKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEA
ELGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC

Sequences:

>Translated_446_residues
MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPM
PTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGAKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYI
EFCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKG
WKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEA
ELGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC
>Mature_445_residues
SDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPMP
TPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGAKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIE
FCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLAF
DGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKGW
KIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAE
LGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=441, Percent_Identity=76.4172335600907, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=449, Percent_Identity=25.3897550111359, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323752, Length=393, Percent_Identity=24.9363867684478, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_VIBC3 (A5F930)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F930
- SMR:   A5F930
- STRING:   A5F930
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0168
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK10887
- BioCyc:   VCHO345073:VC0395_A0168-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47819; Mature: 47687

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 103-103

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
SALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGA
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCC
KLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIEFCKSTFPSKLSLSGLKLVV
CCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
DCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
ECCCCCEEEECHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEE
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGI
EECCCCEEEEEECCCCCCCCCCEEHHEEHHHHHHCCCCCCHHHHHHHHCCHHCCHHHHCC
PFVRAAVGDRYVMEKLLEKGWKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHH
HELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAELGSKGRVLLRKSGTEPLIR
HHHHCCCCHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
VMVEGEDETLVKQSALKIAQAVKDNC
EEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
SALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGA
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCC
KLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIEFCKSTFPSKLSLSGLKLVV
CCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
DCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
ECCCCCEEEECHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEE
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGI
EECCCCEEEEEECCCCCCCCCCEEHHEEHHHHHHCCCCCCHHHHHHHHCCHHCCHHHHCC
PFVRAAVGDRYVMEKLLEKGWKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHH
HELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAELGSKGRVLLRKSGTEPLIR
HHHHCCCCHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
VMVEGEDETLVKQSALKIAQAVKDNC
EEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA