Click here to switch to the map view.

The map label for this gene is nlpI [H]

Identifier: 147674411

GI number: 147674411

Start: 183286

End: 184197

Strand: Direct

Name: nlpI [H]

Synonym: VC0395_A0179

Alternate gene names: 147674411

Gene position: 183286-184197 (Clockwise)

Preceding gene: 147674727

Following gene: 147674022

Centisome position: 6.06

GC content: 49.89

Gene sequence:

>912_bases
GTGAAATGGTTTCGATTCCCGATAGCGGTGATAGGATTGGTTCTGCTGTCAGGGTGTGCCACGCAGAATGAATCTGCAAC
CCAATGGCTTTACCCGCCAATGGCGGTGCCGCTGCAAGCGTCGATTCAACAAGAAGTGCAAATCGCCCGCTTAAGCCAAT
TATTACAGCGCACGGATCTTGAGCCTGAGATACGCGCTAAAATGCTGTTCGAACGTGGCAATTATTACGACAGTGTCGGT
TTACGTGATTTGGCTCGGCTCGATTTTACTCAATCGCTCTCGATTAACCCTGCGCAGCCCGATGTGTTTAACTTGCTAGG
GGTGTATTACACCGAAGCGGGCGAGTTTGACGCCGCGTATGAATCCTTCGATTCGACGTTAGAATTGGATCCTAGTAACG
AGTATGCCGTGCGCAATCGCGCCATCGCGCTTTACTATGGCGAGCGCCCACAACTGGCACTCGAAGAGATCACTAAGCAC
TATCAACAAGACCCACAAGATCCTTTTCGGGCGCTGTGGCTGTACATCATAGAAAGCGATATTGACCTGACAAAAGCGCG
TACAGAACTGCTTGAACGCTATCAGCAGCACGATGAACAGTGGGGCTGGGTGCTGGTAGGACTGATGTTGGATCAACTCT
CGGAAGAGGTCGCATTCAAAGCCATTATTGCGGGCTCTCGAGAAAATGAGCTATTAGCACAGCGCCTCACAGAGGCTTAT
TTCTACCTAGGTAAGCGTTATCAAATGCAAGGAGAACTGGCCCATGCTCTCTCTTTGTATAAGCTCGCGATTTCCTTCAA
TGTGTATGAATATGTGGAGCATCGCTATGCTTTTCTTGAGCTAGGGCACATCTATCAACAAGCCCGTGAAGAGCAGTTAG
CGCGCGCGAAAGCCGAAGCAATGACACAATAG

Upstream 100 bases:

>100_bases
GCAAAAACAACACGGCTTTTACTTTTCATAATAAAAGCGTGCTATAAAGGGAGCGTTATTCGCTCCCTTTTTTATGCGAA
ATCCCACAGGAGTATGATGA

Downstream 100 bases:

>100_bases
TTTCACCTCTCTCTGATAAAAAAGCCGCATCTTGCGGCTTTTTTTGTTGCTAGGACTCTGGCAGAATAGTTAGCCTTGCT
AACTATGTGTTATCGAATAT

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDLEPEIRAKMLFERGNYYDSVG
LRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAYESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKH
YQQDPQDPFRALWLYIIESDIDLTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGHIYQQAREEQLARAKAEAMTQ

Sequences:

>Translated_303_residues
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDLEPEIRAKMLFERGNYYDSVG
LRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAYESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKH
YQQDPQDPFRALWLYIIESDIDLTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGHIYQQAREEQLARAKAEAMTQ
>Mature_303_residues
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDLEPEIRAKMLFERGNYYDSVG
LRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAYESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKH
YQQDPQDPFRALWLYIIESDIDLTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGHIYQQAREEQLARAKAEAMTQ

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=288, Percent_Identity=48.2638888888889, Blast_Score=260, Evalue=9e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 35148; Mature: 35148

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDL
CCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EPEIRAKMLFERGNYYDSVGLRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAY
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
ESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKHYQQDPQDPFRALWLYIIESD
HHCCCEEEECCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
IDLTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGHIYQQAREEQLARAKAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQ
CCC
>Mature Secondary Structure
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDL
CCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EPEIRAKMLFERGNYYDSVGLRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAY
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
ESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKHYQQDPQDPFRALWLYIIESD
HHCCCEEEECCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
IDLTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGHIYQQAREEQLARAKAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]