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The map label for this gene is hscB

Identifier: 147673271

GI number: 147673271

Start: 293980

End: 294495

Strand: Direct

Name: hscB

Synonym: VC0395_A0280

Alternate gene names: 147673271

Gene position: 293980-294495 (Clockwise)

Preceding gene: 147674050

Following gene: 147674764

Centisome position: 9.72

GC content: 48.26

Gene sequence:

>516_bases
ATGAATTATTTTGAATTATTTGGGCTGCCGATCCAGTTTGAACTGGATGGTAGCCTTCTTTCTTCTCAGTTCAGAGCGTT
GCAGAAACGATTCCATCCGGATAATTTTGCTACCGCTTCTGAGCGTGACCGCCTAATGGCAGTGCAGCAAGCCGCGCAAA
TTAACGATGCGTATCAGACACTGAAAGATCCACTCCGCCGCGCGGAATATCTTTTGTCGTTACAAGGCATAGAGATGAAC
GCTGAGCAGCAGACGCTGCAAGATCCGATGTTTCTGATGGAACAGATGGAGCTACGCGAAGAGCTAGAGTCCGTGACGGC
TTGTGCAGATCCAGAGGCCGCCTTAGTCGCTTTTGACACTAAGGTAACCGCGATGCAGCGTCATTATCTCGCACAGCTAC
AAGGCCAATTAGCTCAAAGTGAGTGGTTAGCGGCGGCTGATCAGATCAGAAAGCTCAAATTTATTGCCAAACTCAAAAAT
GAAGTAGAACGAGTCGAAGACCAACTGCTTGGCTAA

Upstream 100 bases:

>100_bases
CAACCCAAATGTCAAAAGCGAATGTGGTTGTGGTGAAAGCTTCAACGTTTAACGGTAACTGACCATCGAGACTGTTCTCG
ATCACAGGACCGCTATCAAG

Downstream 100 bases:

>100_bases
TTCAAGATTCAAAGGAACAACTGATGGCATTACTTCAGATTGCAGAGCCGGGGCAAAGTTCGGCACCACACCAGCATAAG
TTGGCTGCGGGTATTGATTT

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDPLRRAEYLLSLQGIEMN
AEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKN
EVERVEDQLLG

Sequences:

>Translated_171_residues
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDPLRRAEYLLSLQGIEMN
AEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKN
EVERVEDQLLG
>Mature_171_residues
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDPLRRAEYLLSLQGIEMN
AEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKN
EVERVEDQLLG

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=162, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1788876, Length=172, Percent_Identity=50, Blast_Score=160, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17541320, Length=140, Percent_Identity=30.7142857142857, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321420, Length=112, Percent_Identity=36.6071428571429, Blast_Score=64, Evalue=9e-12,
Organism=Drosophila melanogaster, GI161084223, Length=171, Percent_Identity=29.2397660818713, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_VIBC3 (A5F3G7)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F3G7
- SMR:   A5F3G7
- STRING:   A5F3G7
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0280
- eggNOG:   COG1076
- HOGENOM:   HBG751004
- OMA:   LNDAYQT
- ProtClustDB:   PRK05014
- BioCyc:   VCHO345073:VC0395_A0280-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19628; Mature: 19628

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQT
CCHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKDPLRRAEYLLSLQGIEMNAEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECH
KVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKNEVERVEDQLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQT
CCHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKDPLRRAEYLLSLQGIEMNAEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECH
KVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKNEVERVEDQLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA