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The map label for this gene is iorA [H]

Identifier: 146343886

GI number: 146343886

Start: 7451584

End: 7452072

Strand: Reverse

Name: iorA [H]

Synonym: BRADO7137

Alternate gene names: 146343886

Gene position: 7452072-7451584 (Counterclockwise)

Preceding gene: 146343889

Following gene: 146343885

Centisome position: 99.94

GC content: 64.83

Gene sequence:

>489_bases
ATGCCTAATCTCACCATCAATGGGCGGACCATGTCCGTCGATGCGGCGAACGACACGCCGCTGCTATGGGTCATCCGCGA
GCAGTTGCAGATGACCGGCACCAAGTTCGGCTGCGGCGCGGGGCTGTGCGGCGCCTGCACCGTGCACGTCAACGGCGAGG
CGGTGCGCTCGTGCCAGACCATGGTCGGCGACGTCAAGGACAAGAAGATCACCACCATCGAGGGCCTGTCGCAGAAGGGC
GACCATCCCTTGCAGAAGGCGTGGATCGCCGAGCAGGTGCCGCAATGCGGCTACTGCCAGTCGGGGCAGATCATGCAGGC
GGCCTCGCTGCTCGCCAAGACCACGAGCCCGACCAAGGAGGAGATCACAGCGCATATGGACGGCAATCTCTGCCGCTGCA
TGACCTATTCGCGGATCCAGAAGGCGATCCAGCGCGCCGCATCCGAGATGCGCACCGCGTCGAACACCAGCGACCGGAGG
GCGACATGA

Upstream 100 bases:

>100_bases
TTCTTTCGCGCAGGCTGGCATCGAACCGGTGGGTGCCGGCGTCCTCACAAACCGAACTTCGCCGTAAGCGAAGTCGTATG
CCGGGCGGGGAAGAAACCAC

Downstream 100 bases:

>100_bases
ACCAGCACGTGAAAGCAGCGCCCACCATGGCCACAGATCTCAGCCGCCGCTCCTTCCTGGTCGGCACCGCCGCCACCGGC
CTCGTGCTCGGCTATGCCGG

Product: putative aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MPNLTINGRTMSVDAANDTPLLWVIREQLQMTGTKFGCGAGLCGACTVHVNGEAVRSCQTMVGDVKDKKITTIEGLSQKG
DHPLQKAWIAEQVPQCGYCQSGQIMQAASLLAKTTSPTKEEITAHMDGNLCRCMTYSRIQKAIQRAASEMRTASNTSDRR
AT

Sequences:

>Translated_162_residues
MPNLTINGRTMSVDAANDTPLLWVIREQLQMTGTKFGCGAGLCGACTVHVNGEAVRSCQTMVGDVKDKKITTIEGLSQKG
DHPLQKAWIAEQVPQCGYCQSGQIMQAASLLAKTTSPTKEEITAHMDGNLCRCMTYSRIQKAIQRAASEMRTASNTSDRR
AT
>Mature_161_residues
PNLTINGRTMSVDAANDTPLLWVIREQLQMTGTKFGCGAGLCGACTVHVNGEAVRSCQTMVGDVKDKKITTIEGLSQKGD
HPLQKAWIAEQVPQCGYCQSGQIMQAASLLAKTTSPTKEEITAHMDGNLCRCMTYSRIQKAIQRAASEMRTASNTSDRRA
T

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=155, Percent_Identity=33.5483870967742, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=40.2366863905325, Blast_Score=116, Evalue=6e-28,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=39.4366197183099, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=36.241610738255, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=30.379746835443, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=32.484076433121, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=34.375, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=33.9506172839506, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=36.3636363636364, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647199, Length=160, Percent_Identity=35, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=35.1851851851852, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17538; Mature: 17407

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
9.9 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLTINGRTMSVDAANDTPLLWVIREQLQMTGTKFGCGAGLCGACTVHVNGEAVRSCQT
CCCCEECCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHH
MVGDVKDKKITTIEGLSQKGDHPLQKAWIAEQVPQCGYCQSGQIMQAASLLAKTTSPTKE
HHCCCCCCEEEHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHH
EITAHMDGNLCRCMTYSRIQKAIQRAASEMRTASNTSDRRAT
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PNLTINGRTMSVDAANDTPLLWVIREQLQMTGTKFGCGAGLCGACTVHVNGEAVRSCQT
CCCEECCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHH
MVGDVKDKKITTIEGLSQKGDHPLQKAWIAEQVPQCGYCQSGQIMQAASLLAKTTSPTKE
HHCCCCCCEEEHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHH
EITAHMDGNLCRCMTYSRIQKAIQRAASEMRTASNTSDRRAT
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]