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The map label for this gene is flbA [H]

Identifier: 146343872

GI number: 146343872

Start: 7436791

End: 7438749

Strand: Reverse

Name: flbA [H]

Synonym: BRADO7123

Alternate gene names: 146343872

Gene position: 7438749-7436791 (Counterclockwise)

Preceding gene: 146343873

Following gene: 146343871

Centisome position: 99.76

GC content: 68.45

Gene sequence:

>1959_bases
ATGATGAAGCACAAGCCGCACCGGTCCGCCGGCAAATCTCCGGTCAAGTCCGGGTCGGCGGGCCGCGCCGATACGGCGGA
AGCGCTGTGTGACGCGGCGCTGCGGCTGTTGCGGGCCGGCCAGCTAACGAAGGCGGAGGAGACCTGCCGCCGCGCGCTGA
CGCTGGACGCCGCCTCGATCGATGCTCTGCAGGCGATGGGACGCGTCTGTGTCGCGCTCAAGCGGTTCGACGATGCCATC
GAATGGTTTGCCCGTGCCATCCGGCAGGACGTTTCGGTCCCCGACTCCTTCATCGGCCTCGCCCAGGCGCTGCGGCTTGC
CGGCCGGCTCGACGAAGCGATCAAGGCCTATGATCGCGCGCTGCAGCTGCGGCCGGACGCCGTCGAGAGCTGGGACGCGC
TGAGCGAACTGCTGCAGCTGACCGGCCGTCATGCCGAGGCGGCGCTGGCGTGTGACCGGCTGCTGCAGCTGGCGCCCGAC
CGCGCCCCGACATGGTTTCGTCTCGGCGAGTCGCTGGAGGCCGAGGGACGTCGCGACGAGGCGGCGCTGGCGTTCGAACA
GGTGCTCAAGCTGCAGCCGGATCATGTCGACGCCGCCAACAAGGCCGGCGCGGTCCATTTCGATGCCGGGCGGTATGTCG
AGGCGATCGCGCAGTTCGATCAGTCGCTGCGGCAGCAGCCGGACCAGGCCGGCGTGCTGTGCCTGAAGGGCATCTCGCTG
CGGCGGCTGCGCCGCTACGACGAGGCGCAGCCTTTCGGCCAGCGCGCGCATGCTTTGGCGCCGCACGACCCCGACATCGC
CAACAGCTATGGCTGCATCCTGCAGAATCTCGGCCGCCATGACGAAGCGATCACGGTGTTCGAGAAGGCGATCGCCATCC
GGCCGCAGACCGCGGATTTCCACAATCACCGCGGCACCTCGCTGGCCGAATTGCATCGATTCGACGAGGCATTCGCGAGC
TTCGACCGCGCCATCGCGTTGCGGCCGGATTTCGCCGATGCGCATTGGAATGCCGCCTTGTTCCGCCTGCTGGCGGGTGA
TTTCGCGCGCGGCTGGGCGGCGCGTGAATGGGGGCGTCAATGCCGCGCCGTCGGTTTCGTGGAGCGCAGCTTCGACGTGC
CGATGTGGCTCGGGGATGATCCGCTGGAGGGCCGGACCATCCTGCTCCACAGCGATGAGGGTCTTGGCGATACCATTCAG
TTCGCGCGCTACGCGACGATGGTCGCCGCGCGGGGCGCGCGCGTTGTGCTCGAGGTCGATGCGGTGCTGCAGCCGTTGCT
GTCGGGCGTGGACGGCGTGGCGCAATGCCTTGCGCGCGGCGTCGACGCGGTGCCTGCGATCGACATCCATTGTCCATTGT
CCAGCCTGCCGCTCGCCTTCGCGACCCGCCTCGACACGATTCCAGCTGCGCCTGCCTATCTGCCGCGCCCGCCCGACGCG
CGCCGCGCCCTGTGGCAGCAGCGACTCGGGCCGCGCGACCGTCTGCGCGTCGGCCTCGTGTGGTCCGGCAACCCCGCGCA
TCTGAACGACCACAACCGGTCGATGCCGCTGGCGATGCTCGCGCCGCTGCTCGATCTCGATGCGCAGTTCGTCAGCTTGC
AGAAGGGCATACGGCCCGCCGACCAGACGGTGCTCGCCGCGCGTGGCGACATCCTCGACCTCACAGCCGATATCCGCGAC
TTCGTCGACACCGCCGCACTGATCGACGATCTCGATCTCGTCATCACCGTCGACACCAGCGTCGCGCATCTCGCCGGCGC
CATGGGCAGGCCGACCTGGATCATGCTGCCATACACACCCGACTATCGCTGGCTGCTCGATCGTGACGATAGCCCCTGGT
ATCCGAGCCTGCGGCTGTTCCGCCAGGATGCGCGCCGTGATTATGGCGATGTCGTTGCGCGCGTGCGCGCGGCCCTGAAA
CCGCGCGTGGCGGTGTTCGCAACGACTGTCACACGCTAA

Upstream 100 bases:

>100_bases
GGCAACGTCCTGACAGTCGATCTCCCACTGACCGTGACCGCGCAATCTTTCCGCGCATCCGGGAATCATCTACCGCTCGT
GTCACGAGCGCAGAGATCTC

Downstream 100 bases:

>100_bases
CCGGAATGTGATCGCGTTCGTGCGACGAGCGGCGTCGCTGCGCCGGACCGTTTGAGCTGAGTCAACGGAATTTTGCTGCG
CTGTGGCAAACCGGACGCGT

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MMKHKPHRSAGKSPVKSGSAGRADTAEALCDAALRLLRAGQLTKAEETCRRALTLDAASIDALQAMGRVCVALKRFDDAI
EWFARAIRQDVSVPDSFIGLAQALRLAGRLDEAIKAYDRALQLRPDAVESWDALSELLQLTGRHAEAALACDRLLQLAPD
RAPTWFRLGESLEAEGRRDEAALAFEQVLKLQPDHVDAANKAGAVHFDAGRYVEAIAQFDQSLRQQPDQAGVLCLKGISL
RRLRRYDEAQPFGQRAHALAPHDPDIANSYGCILQNLGRHDEAITVFEKAIAIRPQTADFHNHRGTSLAELHRFDEAFAS
FDRAIALRPDFADAHWNAALFRLLAGDFARGWAAREWGRQCRAVGFVERSFDVPMWLGDDPLEGRTILLHSDEGLGDTIQ
FARYATMVAARGARVVLEVDAVLQPLLSGVDGVAQCLARGVDAVPAIDIHCPLSSLPLAFATRLDTIPAAPAYLPRPPDA
RRALWQQRLGPRDRLRVGLVWSGNPAHLNDHNRSMPLAMLAPLLDLDAQFVSLQKGIRPADQTVLAARGDILDLTADIRD
FVDTAALIDDLDLVITVDTSVAHLAGAMGRPTWIMLPYTPDYRWLLDRDDSPWYPSLRLFRQDARRDYGDVVARVRAALK
PRVAVFATTVTR

Sequences:

>Translated_652_residues
MMKHKPHRSAGKSPVKSGSAGRADTAEALCDAALRLLRAGQLTKAEETCRRALTLDAASIDALQAMGRVCVALKRFDDAI
EWFARAIRQDVSVPDSFIGLAQALRLAGRLDEAIKAYDRALQLRPDAVESWDALSELLQLTGRHAEAALACDRLLQLAPD
RAPTWFRLGESLEAEGRRDEAALAFEQVLKLQPDHVDAANKAGAVHFDAGRYVEAIAQFDQSLRQQPDQAGVLCLKGISL
RRLRRYDEAQPFGQRAHALAPHDPDIANSYGCILQNLGRHDEAITVFEKAIAIRPQTADFHNHRGTSLAELHRFDEAFAS
FDRAIALRPDFADAHWNAALFRLLAGDFARGWAAREWGRQCRAVGFVERSFDVPMWLGDDPLEGRTILLHSDEGLGDTIQ
FARYATMVAARGARVVLEVDAVLQPLLSGVDGVAQCLARGVDAVPAIDIHCPLSSLPLAFATRLDTIPAAPAYLPRPPDA
RRALWQQRLGPRDRLRVGLVWSGNPAHLNDHNRSMPLAMLAPLLDLDAQFVSLQKGIRPADQTVLAARGDILDLTADIRD
FVDTAALIDDLDLVITVDTSVAHLAGAMGRPTWIMLPYTPDYRWLLDRDDSPWYPSLRLFRQDARRDYGDVVARVRAALK
PRVAVFATTVTR
>Mature_652_residues
MMKHKPHRSAGKSPVKSGSAGRADTAEALCDAALRLLRAGQLTKAEETCRRALTLDAASIDALQAMGRVCVALKRFDDAI
EWFARAIRQDVSVPDSFIGLAQALRLAGRLDEAIKAYDRALQLRPDAVESWDALSELLQLTGRHAEAALACDRLLQLAPD
RAPTWFRLGESLEAEGRRDEAALAFEQVLKLQPDHVDAANKAGAVHFDAGRYVEAIAQFDQSLRQQPDQAGVLCLKGISL
RRLRRYDEAQPFGQRAHALAPHDPDIANSYGCILQNLGRHDEAITVFEKAIAIRPQTADFHNHRGTSLAELHRFDEAFAS
FDRAIALRPDFADAHWNAALFRLLAGDFARGWAAREWGRQCRAVGFVERSFDVPMWLGDDPLEGRTILLHSDEGLGDTIQ
FARYATMVAARGARVVLEVDAVLQPLLSGVDGVAQCLARGVDAVPAIDIHCPLSSLPLAFATRLDTIPAAPAYLPRPPDA
RRALWQQRLGPRDRLRVGLVWSGNPAHLNDHNRSMPLAMLAPLLDLDAQFVSLQKGIRPADQTVLAARGDILDLTADIRD
FVDTAALIDDLDLVITVDTSVAHLAGAMGRPTWIMLPYTPDYRWLLDRDDSPWYPSLRLFRQDARRDYGDVVARVRAALK
PRVAVFATTVTR

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=442, Percent_Identity=24.2081447963801, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI32307148, Length=450, Percent_Identity=24, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI301336134, Length=334, Percent_Identity=22.7544910179641, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI83415184, Length=334, Percent_Identity=22.7544910179641, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI170784867, Length=355, Percent_Identity=24.7887323943662, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI118766328, Length=235, Percent_Identity=22.9787234042553, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI118766330, Length=235, Percent_Identity=22.9787234042553, Blast_Score=70, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=461, Percent_Identity=22.3427331887202, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115532692, Length=368, Percent_Identity=24.4565217391304, Blast_Score=102, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6319387, Length=226, Percent_Identity=24.3362831858407, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320450, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647755, Length=452, Percent_Identity=23.4513274336283, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24585827, Length=452, Percent_Identity=23.4513274336283, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24585829, Length=452, Percent_Identity=23.4513274336283, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647123, Length=230, Percent_Identity=24.7826086956522, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076610, Length=319, Percent_Identity=26.6457680250784, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920486, Length=319, Percent_Identity=26.6457680250784, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364285, Length=313, Percent_Identity=24.2811501597444, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581187, Length=313, Percent_Identity=24.2811501597444, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 71951; Mature: 71951

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKHKPHRSAGKSPVKSGSAGRADTAEALCDAALRLLRAGQLTKAEETCRRALTLDAASI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
DALQAMGRVCVALKRFDDAIEWFARAIRQDVSVPDSFIGLAQALRLAGRLDEAIKAYDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQLRPDAVESWDALSELLQLTGRHAEAALACDRLLQLAPDRAPTWFRLGESLEAEGRRDE
HHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHH
AALAFEQVLKLQPDHVDAANKAGAVHFDAGRYVEAIAQFDQSLRQQPDQAGVLCLKGISL
HHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHCEEHHCCHHH
RRLRRYDEAQPFGQRAHALAPHDPDIANSYGCILQNLGRHDEAITVFEKAIAIRPQTADF
HHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
HNHRGTSLAELHRFDEAFASFDRAIALRPDFADAHWNAALFRLLAGDFARGWAAREWGRQ
CCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
CRAVGFVERSFDVPMWLGDDPLEGRTILLHSDEGLGDTIQFARYATMVAARGARVVLEVD
HHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEHH
AVLQPLLSGVDGVAQCLARGVDAVPAIDIHCPLSSLPLAFATRLDTIPAAPAYLPRPPDA
HHHHHHHHCHHHHHHHHHCCCCCCCEEEEECCHHHCHHHHHHHHCCCCCCCCCCCCCCHH
RRALWQQRLGPRDRLRVGLVWSGNPAHLNDHNRSMPLAMLAPLLDLDAQFVSLQKGIRPA
HHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DQTVLAARGDILDLTADIRDFVDTAALIDDLDLVITVDTSVAHLAGAMGRPTWIMLPYTP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCEEEEEECCC
DYRWLLDRDDSPWYPSLRLFRQDARRDYGDVVARVRAALKPRVAVFATTVTR
CCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MMKHKPHRSAGKSPVKSGSAGRADTAEALCDAALRLLRAGQLTKAEETCRRALTLDAASI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
DALQAMGRVCVALKRFDDAIEWFARAIRQDVSVPDSFIGLAQALRLAGRLDEAIKAYDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQLRPDAVESWDALSELLQLTGRHAEAALACDRLLQLAPDRAPTWFRLGESLEAEGRRDE
HHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHH
AALAFEQVLKLQPDHVDAANKAGAVHFDAGRYVEAIAQFDQSLRQQPDQAGVLCLKGISL
HHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHCEEHHCCHHH
RRLRRYDEAQPFGQRAHALAPHDPDIANSYGCILQNLGRHDEAITVFEKAIAIRPQTADF
HHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
HNHRGTSLAELHRFDEAFASFDRAIALRPDFADAHWNAALFRLLAGDFARGWAAREWGRQ
CCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
CRAVGFVERSFDVPMWLGDDPLEGRTILLHSDEGLGDTIQFARYATMVAARGARVVLEVD
HHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEHH
AVLQPLLSGVDGVAQCLARGVDAVPAIDIHCPLSSLPLAFATRLDTIPAAPAYLPRPPDA
HHHHHHHHCHHHHHHHHHCCCCCCCEEEEECCHHHCHHHHHHHHCCCCCCCCCCCCCCHH
RRALWQQRLGPRDRLRVGLVWSGNPAHLNDHNRSMPLAMLAPLLDLDAQFVSLQKGIRPA
HHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DQTVLAARGDILDLTADIRDFVDTAALIDDLDLVITVDTSVAHLAGAMGRPTWIMLPYTP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCEEEEEECCC
DYRWLLDRDDSPWYPSLRLFRQDARRDYGDVVARVRAALKPRVAVFATTVTR
CCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748431; 11259647; 1699845 [H]