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The map label for this gene is phoP [H]

Identifier: 146343748

GI number: 146343748

Start: 7294144

End: 7294614

Strand: Direct

Name: phoP [H]

Synonym: BRADO6995

Alternate gene names: 146343748

Gene position: 7294144-7294614 (Clockwise)

Preceding gene: 146343745

Following gene: 146343749

Centisome position: 97.82

GC content: 63.48

Gene sequence:

>471_bases
TTGGTCTTGCTGCCAACCATTCGGGAGGCGCGGAGCGTGGCGAACATACTGGTCGTGGACGACGACCCTGTCATGCAGCT
GACCATTCAGCGCGTGCTCGAACGCGCTGGACATGCCGTGGCGACGGCCGGCGACGGGCAGAAGGCGCTTGCGCGTTTCG
AGCGCGAAAGCTTCGATCTCGTCATCCTCGACATCTTCATGCCGGGCATGGACGGGCTGGAAGCCATGCGCATGATCCTG
CAGCGCGCGCCGGGCGTTCCGATCCTGATGACATCGGGGCGACCGCAGACCGCAAGCTCGATTTCCGAGCCCGATTATCT
TACCATGGCGACCAAGCTGGGAGCGGTTTCCGCCTTGCCCAAGCCGTTCAAACCGGCTGACCTCGTGACGATGGTTTCCG
ATTGCCTGGCGTCGGCAGGCAATCCGGCTGAGCGACCACGGCCAGGCCACGATGCTGTTCCGAACTCCTGA

Upstream 100 bases:

>100_bases
AAGGCGGCATTCGCGGGCCGGCCGATGACCGCACATGTGACTTGAGTCGTCTGGCGCTTGCAGCGCGCCGCGAATTGGGC
AAAACCTCTACAACTGACTG

Downstream 100 bases:

>100_bases
CAGCCGAGCCAATCATGCGTCGCTGAGCGGCCTCGAAGGCGCCAGCGATGGCAGCCTTGGCCATCGCATGTCGCTGACGA
CACGGCTGGCAATCGCGATG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MVLLPTIREARSVANILVVDDDPVMQLTIQRVLERAGHAVATAGDGQKALARFERESFDLVILDIFMPGMDGLEAMRMIL
QRAPGVPILMTSGRPQTASSISEPDYLTMATKLGAVSALPKPFKPADLVTMVSDCLASAGNPAERPRPGHDAVPNS

Sequences:

>Translated_156_residues
MVLLPTIREARSVANILVVDDDPVMQLTIQRVLERAGHAVATAGDGQKALARFERESFDLVILDIFMPGMDGLEAMRMIL
QRAPGVPILMTSGRPQTASSISEPDYLTMATKLGAVSALPKPFKPADLVTMVSDCLASAGNPAERPRPGHDAVPNS
>Mature_156_residues
MVLLPTIREARSVANILVVDDDPVMQLTIQRVLERAGHAVATAGDGQKALARFERESFDLVILDIFMPGMDGLEAMRMIL
QRAPGVPILMTSGRPQTASSISEPDYLTMATKLGAVSALPKPFKPADLVTMVSDCLASAGNPAERPRPGHDAVPNS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=29.9212598425197, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=31.0606060606061, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=31.7073170731707, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788905, Length=135, Percent_Identity=34.8148148148148, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 16677; Mature: 16677

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLPTIREARSVANILVVDDDPVMQLTIQRVLERAGHAVATAGDGQKALARFERESFDL
CEECCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCE
VILDIFMPGMDGLEAMRMILQRAPGVPILMTSGRPQTASSISEPDYLTMATKLGAVSALP
EEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHHHCCC
KPFKPADLVTMVSDCLASAGNPAERPRPGHDAVPNS
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVLLPTIREARSVANILVVDDDPVMQLTIQRVLERAGHAVATAGDGQKALARFERESFDL
CEECCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCE
VILDIFMPGMDGLEAMRMILQRAPGVPILMTSGRPQTASSISEPDYLTMATKLGAVSALP
EEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHHHCCC
KPFKPADLVTMVSDCLASAGNPAERPRPGHDAVPNS
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]