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The map label for this gene is metA [H]

Identifier: 146343670

GI number: 146343670

Start: 7183416

End: 7184393

Strand: Direct

Name: metA [H]

Synonym: BRADO6913

Alternate gene names: 146343670

Gene position: 7183416-7184393 (Clockwise)

Preceding gene: 146343669

Following gene: 146343672

Centisome position: 96.34

GC content: 66.77

Gene sequence:

>978_bases
ATGACCCTGCTGTTCGACGGAGATCGCAGGATCAAGAGCCCTGCTCTCGCGCCCGCCGGCGGCGACCGTCGCGCGCGCGA
CCCGATCGAGCTGACGATCGGGCTCGTCAACAACATGCCGGACAGCGCGCTGAAGGCAACCGATGTCCAAATCGCACGGC
TGCTGCAACAAGCCGCGCCGTGGCACGTTCGCATCCGCCTGCACTGCTTCTCGCTGCCGTCGATTGCACGTTCGCCTATG
GCCAGCAGCCACGTTGCCCAGACCTACACCGACATCGACCGGCTCGATGGCCTCGACATCGACGGCCTGATCGTCACCGG
CGCCGAGCCGGTCGCGGCAAGACTCCGCGACGAGTCCTATTGGCCGGACCTCGCCGCGATCGTCGACTGGGCCAGGACCA
ACACGAAGACGACGATCTGGTCCTGCCTCGCCGCGCATGCCGCGGTGCTGCATCTCGACGACATCGAGCGGCAGCGGCTG
GCCTCGAAATGCTCCGGCGTCTTCGACTGCGTGAAGGTTCGGGACGACTGGCTGACCCACGGCATCGACGCGCCGCTGCA
GGTGCCGCACTCGCGGCTGAACGCCGTCAACGAGCCGCTGCTGGCGGAGCGCGGCTACGACATCCTGACCCGGTCCGCCG
AGGTCGGCGTCGACATCTTCGCACGCACGATGCCGAGCCGCTTCGTGTTCTTCCAGGGTCACCCCGAGTATGACGCGCTG
TCGCTGCAGCGTGAATACATGCGCGACATCGCACGGTATCTCGCCGGCCAGCGCGAGGACTATCCGCGGCCGCCGAGATC
CTATTTCAGCGCCGAGAGCGAGGCGGTGCTGAACACGTTCGAGATCAGGGCCAGGGCACGGCGGGATCCGACGCTGGCGG
CCGAACTGCCAGGGCTCACGCTGCGCCCGGATCTTGCGGCCGGTCATGCCGCAAAACTCCTGTTCAGGAACTGGATCGGC
TATCTCGCCGATGGCTAA

Upstream 100 bases:

>100_bases
CGGCATCGAGCATATCGACGACATCATCGAAGATCTCGACCAGGCGCTGGCCCTGGCCTGCCCGCGTCAGCTGGACGCGG
CGGAGTAGAGCGATCAGCCG

Downstream 100 bases:

>100_bases
CGCCATCGCGAATCATCCTTTCTCGCCCAGCGAGGCCAGCGCAGCATTGCCGCCGGCCGCTGCGGTGTTGACCGTCATCG
TCTGCTCGGTGGCGAAGCGT

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTLLFDGDRRIKSPALAPAGGDRRARDPIELTIGLVNNMPDSALKATDVQIARLLQQAAPWHVRIRLHCFSLPSIARSPM
ASSHVAQTYTDIDRLDGLDIDGLIVTGAEPVAARLRDESYWPDLAAIVDWARTNTKTTIWSCLAAHAAVLHLDDIERQRL
ASKCSGVFDCVKVRDDWLTHGIDAPLQVPHSRLNAVNEPLLAERGYDILTRSAEVGVDIFARTMPSRFVFFQGHPEYDAL
SLQREYMRDIARYLAGQREDYPRPPRSYFSAESEAVLNTFEIRARARRDPTLAAELPGLTLRPDLAAGHAAKLLFRNWIG
YLADG

Sequences:

>Translated_325_residues
MTLLFDGDRRIKSPALAPAGGDRRARDPIELTIGLVNNMPDSALKATDVQIARLLQQAAPWHVRIRLHCFSLPSIARSPM
ASSHVAQTYTDIDRLDGLDIDGLIVTGAEPVAARLRDESYWPDLAAIVDWARTNTKTTIWSCLAAHAAVLHLDDIERQRL
ASKCSGVFDCVKVRDDWLTHGIDAPLQVPHSRLNAVNEPLLAERGYDILTRSAEVGVDIFARTMPSRFVFFQGHPEYDAL
SLQREYMRDIARYLAGQREDYPRPPRSYFSAESEAVLNTFEIRARARRDPTLAAELPGLTLRPDLAAGHAAKLLFRNWIG
YLADG
>Mature_324_residues
TLLFDGDRRIKSPALAPAGGDRRARDPIELTIGLVNNMPDSALKATDVQIARLLQQAAPWHVRIRLHCFSLPSIARSPMA
SSHVAQTYTDIDRLDGLDIDGLIVTGAEPVAARLRDESYWPDLAAIVDWARTNTKTTIWSCLAAHAAVLHLDDIERQRLA
SKCSGVFDCVKVRDDWLTHGIDAPLQVPHSRLNAVNEPLLAERGYDILTRSAEVGVDIFARTMPSRFVFFQGHPEYDALS
LQREYMRDIARYLAGQREDYPRPPRSYFSAESEAVLNTFEIRARARRDPTLAAELPGLTLRPDLAAGHAAKLLFRNWIGY
LADG

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=243, Percent_Identity=30.8641975308642, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36276; Mature: 36144

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLFDGDRRIKSPALAPAGGDRRARDPIELTIGLVNNMPDSALKATDVQIARLLQQAAP
CEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
WHVRIRLHCFSLPSIARSPMASSHVAQTYTDIDRLDGLDIDGLIVTGAEPVAARLRDESY
EEEEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCC
WPDLAAIVDWARTNTKTTIWSCLAAHAAVLHLDDIERQRLASKCSGVFDCVKVRDDWLTH
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIDAPLQVPHSRLNAVNEPLLAERGYDILTRSAEVGVDIFARTMPSRFVFFQGHPEYDAL
CCCCCCCCCHHHHHHCCCCHHHHCCCHHHHCCHHHCHHHHHHHCCCEEEEEECCCCCHHH
SLQREYMRDIARYLAGQREDYPRPPRSYFSAESEAVLNTFEIRARARRDPTLAAELPGLT
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCE
LRPDLAAGHAAKLLFRNWIGYLADG
ECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLLFDGDRRIKSPALAPAGGDRRARDPIELTIGLVNNMPDSALKATDVQIARLLQQAAP
EEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
WHVRIRLHCFSLPSIARSPMASSHVAQTYTDIDRLDGLDIDGLIVTGAEPVAARLRDESY
EEEEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCC
WPDLAAIVDWARTNTKTTIWSCLAAHAAVLHLDDIERQRLASKCSGVFDCVKVRDDWLTH
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIDAPLQVPHSRLNAVNEPLLAERGYDILTRSAEVGVDIFARTMPSRFVFFQGHPEYDAL
CCCCCCCCCHHHHHHCCCCHHHHCCCHHHHCCHHHCHHHHHHHCCCEEEEEECCCCCHHH
SLQREYMRDIARYLAGQREDYPRPPRSYFSAESEAVLNTFEIRARARRDPTLAAELPGLT
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCE
LRPDLAAGHAAKLLFRNWIGYLADG
ECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA