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The map label for this gene is coxG

Identifier: 146343473

GI number: 146343473

Start: 6962213

End: 6962872

Strand: Reverse

Name: coxG

Synonym: BRADO6703

Alternate gene names: 146343473

Gene position: 6962872-6962213 (Counterclockwise)

Preceding gene: 146343474

Following gene: 146343472

Centisome position: 93.38

GC content: 68.18

Gene sequence:

>660_bases
ATGGACGCGACCGACCAGGGCAAATCGACGAGCACGACCGCTGCGCAGGCTGCGCCGGGCAAGGCCGCGCCACGCCGTGG
CATCGGCCGCGATGCGCTGGTCGGCGGCATCTGCGGCGCCGTGGTGGTGCTGATGATCGGAGCCTCCTACGCTGCCGTGC
CGTTCTACAACTGGTTCTGCCGCGCCACCGGCTTCAACGGCACCACCCAGGTCGCGACCGCTGCGCCCTCGGCCGCGCCG
CTGGCGCGCCGCATCGGCGTCCGCTTCGACGCCAATGTCGCCGGCGGGCTGCCCTGGAAGTTCGAGCCGGAAAAGACCGA
GATCGAGGTCGCGATCGGCGAAGTCGTCACGGTCTATTACACCGTGACCAACCAGTCGGCGCGCACCACCATGGCGCAGG
CCGCCTACAATGTGACGCCGCTGACCTCGGGCGCCTATTTCCAGAAGATCAACTGCTTCTGCTTCACCGAGCAGACCATG
GCCCCGGGCGAGACCCGCGAGATGCCGGTCGTGTTCTACGTCGATCCGGCGATCACCGCCGATCACGAGAACGACGGTCT
GAACACGATCACATTGTCCTACACCTTCTATCCCGTCCGCGACGCCGCGCCGAAGCCGGTCGCCGCGGGCGAGCCGGACA
AGCCGCGGGGCAGCCTGTGA

Upstream 100 bases:

>100_bases
CGCGATCGCCTTGGCGCTCGGCGTGCTCGTGGTGCTGTTCTTCGCCGTGACCATGGTGAAGGGCCCGATCGTTCTGAAGC
GGCCGATGTAGAGAGACGCG

Downstream 100 bases:

>100_bases
CCGCGCGGCCATTCGATATCCGGGGACGTTTTTTGAGCGATACTTTGCCGGGGCGACCGGCATCGATCTGGGGAGAGACT
TGCCATGGCTGAGGCGCACG

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MDATDQGKSTSTTAAQAAPGKAAPRRGIGRDALVGGICGAVVVLMIGASYAAVPFYNWFCRATGFNGTTQVATAAPSAAP
LARRIGVRFDANVAGGLPWKFEPEKTEIEVAIGEVVTVYYTVTNQSARTTMAQAAYNVTPLTSGAYFQKINCFCFTEQTM
APGETREMPVVFYVDPAITADHENDGLNTITLSYTFYPVRDAAPKPVAAGEPDKPRGSL

Sequences:

>Translated_219_residues
MDATDQGKSTSTTAAQAAPGKAAPRRGIGRDALVGGICGAVVVLMIGASYAAVPFYNWFCRATGFNGTTQVATAAPSAAP
LARRIGVRFDANVAGGLPWKFEPEKTEIEVAIGEVVTVYYTVTNQSARTTMAQAAYNVTPLTSGAYFQKINCFCFTEQTM
APGETREMPVVFYVDPAITADHENDGLNTITLSYTFYPVRDAAPKPVAAGEPDKPRGSL
>Mature_219_residues
MDATDQGKSTSTTAAQAAPGKAAPRRGIGRDALVGGICGAVVVLMIGASYAAVPFYNWFCRATGFNGTTQVATAAPSAAP
LARRIGVRFDANVAGGLPWKFEPEKTEIEVAIGEVVTVYYTVTNQSARTTMAQAAYNVTPLTSGAYFQKINCFCFTEQTM
APGETREMPVVFYVDPAITADHENDGLNTITLSYTFYPVRDAAPKPVAAGEPDKPRGSL

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family

Homologues:

Organism=Homo sapiens, GI4758034, Length=172, Percent_Identity=39.5348837209302, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI242247057, Length=124, Percent_Identity=35.4838709677419, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI242247061, Length=116, Percent_Identity=37.0689655172414, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71990692, Length=188, Percent_Identity=37.2340425531915, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6325125, Length=198, Percent_Identity=35.8585858585859, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24581944, Length=163, Percent_Identity=42.9447852760736, Blast_Score=150, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXZ_BRASO (A4Z2D0)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001208521.1
- ProteinModelPortal:   A4Z2D0
- SMR:   A4Z2D0
- STRING:   A4Z2D0
- GeneID:   5115952
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO6703
- eggNOG:   COG3175
- HOGENOM:   HBG525908
- OMA:   SNNDIIG
- ProtClustDB:   PRK05089
- BioCyc:   BSP376:BRADO6703-MONOMER
- HAMAP:   MF_00155
- InterPro:   IPR007533
- Gene3D:   G3DSA:2.60.370.10
- PANTHER:   PTHR21320
- PIRSF:   PIRSF005413

Pfam domain/function: PF04442 CtaG_Cox11; SSF110111 CtaG_Cox11

EC number: NA

Molecular weight: Translated: 23172; Mature: 23172

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2169fc70)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATDQGKSTSTTAAQAAPGKAAPRRGIGRDALVGGICGAVVVLMIGASYAAVPFYNWFC
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEE
RATGFNGTTQVATAAPSAAPLARRIGVRFDANVAGGLPWKFEPEKTEIEVAIGEVVTVYY
EECCCCCCCEEEECCCCHHHHHHHHCCEECCCCCCCCCCEECCCCCEEEEEECCEEEEEE
TVTNQSARTTMAQAAYNVTPLTSGAYFQKINCFCFTEQTMAPGETREMPVVFYVDPAITA
EEECCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCEEC
DHENDGLNTITLSYTFYPVRDAAPKPVAAGEPDKPRGSL
CCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MDATDQGKSTSTTAAQAAPGKAAPRRGIGRDALVGGICGAVVVLMIGASYAAVPFYNWFC
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEE
RATGFNGTTQVATAAPSAAPLARRIGVRFDANVAGGLPWKFEPEKTEIEVAIGEVVTVYY
EECCCCCCCEEEECCCCHHHHHHHHCCEECCCCCCCCCCEECCCCCEEEEEECCEEEEEE
TVTNQSARTTMAQAAYNVTPLTSGAYFQKINCFCFTEQTMAPGETREMPVVFYVDPAITA
EEECCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCEEC
DHENDGLNTITLSYTFYPVRDAAPKPVAAGEPDKPRGSL
CCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA