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The map label for this gene is coxC [H]

Identifier: 146343472

GI number: 146343472

Start: 6961271

End: 6962128

Strand: Reverse

Name: coxC [H]

Synonym: BRADO6702

Alternate gene names: 146343472

Gene position: 6962128-6961271 (Counterclockwise)

Preceding gene: 146343473

Following gene: 146343471

Centisome position: 93.37

GC content: 64.45

Gene sequence:

>858_bases
ATGGCTGAGGCGCACGCCAAGCATCACGACTACCACCTCGTTGATCCGAGCCCTTGGCCGTTCGTCGGCTCGGTGTCGGC
CTTCATCATGGCGTTCGGCGCCATCGGCTGGATGCACAAGATGTTCGGCGCCGCGCCGATCGTGTTCGGCATCGGCCTGA
TCGGCGTGCTCTACACCATGGCGAGCTGGTGGGGCGACGTCATCAAGGAAGCCCAGTACAAGGGCGACCACACCCGCGTG
GTGCAGCTGCATCACCGCTACGGCATGATCCTGTTCATCGCCTCCGAGGTGATGTTCTTCGTCGCCTGGTTCTGGGCCTA
TTTCAACGTCGCGCTGTTCCCGGGCTACGAGGTGCAGGCGACCCGCGACGCGCTGATCGGCGGTGTCTGGCCGCCCAAGG
GCATCGAGACCTTCGATCCCTGGCATCTGCCGCTGCTCAACACGCTGATCCTGCTGACCTCGGGCACGACAGTCACCTGG
GCGCACCACGCGCTGCTCGAAGGCGACCGCAAGGGCCTGAAATACGGCCTCATCCTCACCATCCTGCTCGGCGCCACCTT
CACCTGCGTCCAGGCCTATGAGTACGGCCACGCGACCTTCTCGTTCGCCGGCCACATCTACGGCTCGACCTTCTTCATGG
CGACCGGCTTCCACGGCTTCCACGTGCTGGTCGGCACGATCTTCCTGATCGTCTGCCTGGCGCGCGCCTATGCCGGCCAC
TTCACGCCGAAGCAGCATCTCGGCTTCGAGTTCGCCGCTTGGTACTGGCACTTCGTCGACGTGGTCTGGCTGTTCCTGTT
CCTCTGCATCTACGTCTGGGGCCACGGCGCCGAGTCGATGGCGCACGGCGCACACTGA

Upstream 100 bases:

>100_bases
GCGGGGCAGCCTGTGACCGCGCGGCCATTCGATATCCGGGGACGTTTTTTGAGCGATACTTTGCCGGGGCGACCGGCATC
GATCTGGGGAGAGACTTGCC

Downstream 100 bases:

>100_bases
CGCGGCAAGCGGACGGACTCCGTCGAACGTGTCATCGAGGGCGGCCGTCGGGCCGCCCTTTCTCGTTGAGCGGCGCTGCG
AATGGTGATCCAAATGTGAT

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MAEAHAKHHDYHLVDPSPWPFVGSVSAFIMAFGAIGWMHKMFGAAPIVFGIGLIGVLYTMASWWGDVIKEAQYKGDHTRV
VQLHHRYGMILFIASEVMFFVAWFWAYFNVALFPGYEVQATRDALIGGVWPPKGIETFDPWHLPLLNTLILLTSGTTVTW
AHHALLEGDRKGLKYGLILTILLGATFTCVQAYEYGHATFSFAGHIYGSTFFMATGFHGFHVLVGTIFLIVCLARAYAGH
FTPKQHLGFEFAAWYWHFVDVVWLFLFLCIYVWGHGAESMAHGAH

Sequences:

>Translated_285_residues
MAEAHAKHHDYHLVDPSPWPFVGSVSAFIMAFGAIGWMHKMFGAAPIVFGIGLIGVLYTMASWWGDVIKEAQYKGDHTRV
VQLHHRYGMILFIASEVMFFVAWFWAYFNVALFPGYEVQATRDALIGGVWPPKGIETFDPWHLPLLNTLILLTSGTTVTW
AHHALLEGDRKGLKYGLILTILLGATFTCVQAYEYGHATFSFAGHIYGSTFFMATGFHGFHVLVGTIFLIVCLARAYAGH
FTPKQHLGFEFAAWYWHFVDVVWLFLFLCIYVWGHGAESMAHGAH
>Mature_284_residues
AEAHAKHHDYHLVDPSPWPFVGSVSAFIMAFGAIGWMHKMFGAAPIVFGIGLIGVLYTMASWWGDVIKEAQYKGDHTRVV
QLHHRYGMILFIASEVMFFVAWFWAYFNVALFPGYEVQATRDALIGGVWPPKGIETFDPWHLPLLNTLILLTSGTTVTWA
HHALLEGDRKGLKYGLILTILLGATFTCVQAYEYGHATFSFAGHIYGSTFFMATGFHGFHVLVGTIFLIVCLARAYAGHF
TPKQHLGFEFAAWYWHFVDVVWLFLFLCIYVWGHGAESMAHGAH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=268, Percent_Identity=48.8805970149254, Blast_Score=242, Evalue=2e-64,
Organism=Escherichia coli, GI1786633, Length=177, Percent_Identity=29.9435028248588, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6226542, Length=274, Percent_Identity=38.6861313868613, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32064; Mature: 31932

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAHAKHHDYHLVDPSPWPFVGSVSAFIMAFGAIGWMHKMFGAAPIVFGIGLIGVLYTM
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ASWWGDVIKEAQYKGDHTRVVQLHHRYGMILFIASEVMFFVAWFWAYFNVALFPGYEVQA
HHHHHHHHHHHHCCCCCHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
TRDALIGGVWPPKGIETFDPWHLPLLNTLILLTSGTTVTWAHHALLEGDRKGLKYGLILT
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCHHHHHHHH
ILLGATFTCVQAYEYGHATFSFAGHIYGSTFFMATGFHGFHVLVGTIFLIVCLARAYAGH
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
FTPKQHLGFEFAAWYWHFVDVVWLFLFLCIYVWGHGAESMAHGAH
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
AEAHAKHHDYHLVDPSPWPFVGSVSAFIMAFGAIGWMHKMFGAAPIVFGIGLIGVLYTM
CCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ASWWGDVIKEAQYKGDHTRVVQLHHRYGMILFIASEVMFFVAWFWAYFNVALFPGYEVQA
HHHHHHHHHHHHCCCCCHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
TRDALIGGVWPPKGIETFDPWHLPLLNTLILLTSGTTVTWAHHALLEGDRKGLKYGLILT
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCHHHHHHHH
ILLGATFTCVQAYEYGHATFSFAGHIYGSTFFMATGFHGFHVLVGTIFLIVCLARAYAGH
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
FTPKQHLGFEFAAWYWHFVDVVWLFLFLCIYVWGHGAESMAHGAH
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]