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The map label for this gene is fabG [H]

Identifier: 146343214

GI number: 146343214

Start: 6677628

End: 6678410

Strand: Direct

Name: fabG [H]

Synonym: BRADO6424

Alternate gene names: 146343214

Gene position: 6677628-6678410 (Clockwise)

Preceding gene: 146343213

Following gene: 146343216

Centisome position: 89.55

GC content: 68.97

Gene sequence:

>783_bases
GTGGATCTCGGGATCAAGGGCCGCCGCGCCATCGTCTGCGCCTCCAGCAAGGGTTTGGGCCGCGCCTGCGCCATCGCGCT
GGCCAATGAGGGCGTCGACGTCACGATCACCGCGCGTGGCGCCGAGGCGCTGGCCAAGACCGCGGCGGAGATCCGCGCCG
CCAATCCCGGCATCACCGTGACCGAGGTGCCCGGCGACATCACCACGCCGGAAGGCCGCGCCGCCGTGCTCAAAGCCTGC
CCGGATCCGGACATCCTGATCAACAATGCCGGCGGCCCGCCGCCCGGCGACTTCCGCAACTGGACCCGCGACGACTGGAT
CAAGGCGCTCGATGCCAACATGCTGACGCCGATCGAGCTGATCAAGGCGACCGTCGACGGCATGATGGCGCGCAAGTTCG
GCCGCATCGTCAACATCACCTCGGCCGCGGTGAAGGCGCCGATCGACATTCTGGGCCTGTCCAACGGCGCCCGCGCCGGA
CTCACCGGCTTCGTCGCCGGCCTGTCGCGCAAGACGGTGATCAACAATGTGACGATCAATGCGCTGCTGCCGGGCCCGTT
CGAGACCGACCGGCTGCGCTCGACAGCCAAGGGCGAAGCCGAGAAGCGCGGCGTCACGCCGGAGCAGATCCTGGCCGACC
GCGCCAAGACCAACCCCGCCGGCCGCTTCGGCGATCCCGAAGAATTTGGCCTCGCCTGTGCCTTCCTGTGCGCCGCCAAG
GCCGGCTACATCACCGGGCAGAACATCCTGCTGGACGGTGGTGCATTCCCGGGCACGCTGTAG

Upstream 100 bases:

>100_bases
ATGCAATTCGGCACAGGCCGGCTGCTCTTATCAGCCGCGGTCCGGTTGGTTAGAATGCACCCATCGTTTTTCCACCCCAC
ACATATCGGAGTGATCAATC

Downstream 100 bases:

>100_bases
GTCGTATTGCAAGAGTGGAGTAAAGAGCTCTCGCCGCTTGTTCGGTCTGCGCCTCTCCCCGCCTGCGGGGAGAGGTCGGA
TCGCATCGCCAGATACGATC

Product: putative short-chain reductase/dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDLGIKGRRAIVCASSKGLGRACAIALANEGVDVTITARGAEALAKTAAEIRAANPGITVTEVPGDITTPEGRAAVLKAC
PDPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIELIKATVDGMMARKFGRIVNITSAAVKAPIDILGLSNGARAG
LTGFVAGLSRKTVINNVTINALLPGPFETDRLRSTAKGEAEKRGVTPEQILADRAKTNPAGRFGDPEEFGLACAFLCAAK
AGYITGQNILLDGGAFPGTL

Sequences:

>Translated_260_residues
MDLGIKGRRAIVCASSKGLGRACAIALANEGVDVTITARGAEALAKTAAEIRAANPGITVTEVPGDITTPEGRAAVLKAC
PDPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIELIKATVDGMMARKFGRIVNITSAAVKAPIDILGLSNGARAG
LTGFVAGLSRKTVINNVTINALLPGPFETDRLRSTAKGEAEKRGVTPEQILADRAKTNPAGRFGDPEEFGLACAFLCAAK
AGYITGQNILLDGGAFPGTL
>Mature_260_residues
MDLGIKGRRAIVCASSKGLGRACAIALANEGVDVTITARGAEALAKTAAEIRAANPGITVTEVPGDITTPEGRAAVLKAC
PDPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIELIKATVDGMMARKFGRIVNITSAAVKAPIDILGLSNGARAG
LTGFVAGLSRKTVINNVTINALLPGPFETDRLRSTAKGEAEKRGVTPEQILADRAKTNPAGRFGDPEEFGLACAFLCAAK
AGYITGQNILLDGGAFPGTL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=28.8, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=27.2373540856031, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=25.8964143426295, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=26.2931034482759, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=24.8091603053435, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=30, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=28.4, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=28.2442748091603, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=25.390625, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=30.952380952381, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=32.824427480916, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=30.9433962264151, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=32.0610687022901, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=31.5589353612167, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=30.2681992337165, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=32.6923076923077, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=28.4132841328413, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=31.1787072243346, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=30.4832713754647, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=28.7937743190661, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.8195488721804, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=28.996282527881, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=29.368029739777, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=30.6513409961686, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=28.1368821292776, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=27.6679841897233, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=28.6245353159851, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=27.7566539923954, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=25.8964143426295, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=25.0965250965251, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=23.6, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=28.1481481481481, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=26.2745098039216, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=28.0632411067194, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=25.390625, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=25.7692307692308, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=29.3436293436293, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26916; Mature: 26916

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIKGRRAIVCASSKGLGRACAIALANEGVDVTITARGAEALAKTAAEIRAANPGITV
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHCCCCCEEE
TEVPGDITTPEGRAAVLKACPDPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIEL
EECCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHH
IKATVDGMMARKFGRIVNITSAAVKAPIDILGLSNGARAGLTGFVAGLSRKTVINNVTIN
HHHHHHHHHHHHHHCEEEEHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCEEECCEEEE
ALLPGPFETDRLRSTAKGEAEKRGVTPEQILADRAKTNPAGRFGDPEEFGLACAFLCAAK
EEECCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AGYITGQNILLDGGAFPGTL
CCEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MDLGIKGRRAIVCASSKGLGRACAIALANEGVDVTITARGAEALAKTAAEIRAANPGITV
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHCCCCCEEE
TEVPGDITTPEGRAAVLKACPDPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIEL
EECCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHH
IKATVDGMMARKFGRIVNITSAAVKAPIDILGLSNGARAGLTGFVAGLSRKTVINNVTIN
HHHHHHHHHHHHHHCEEEEHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCEEECCEEEE
ALLPGPFETDRLRSTAKGEAEKRGVTPEQILADRAKTNPAGRFGDPEEFGLACAFLCAAK
EEECCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AGYITGQNILLDGGAFPGTL
CCEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]