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The map label for this gene is plcH [H]

Identifier: 146343153

GI number: 146343153

Start: 6605447

End: 6607312

Strand: Direct

Name: plcH [H]

Synonym: BRADO6351

Alternate gene names: 146343153

Gene position: 6605447-6607312 (Clockwise)

Preceding gene: 146343152

Following gene: 146343154

Centisome position: 88.59

GC content: 63.56

Gene sequence:

>1866_bases
ATGACCAGAACAGTCATACGGTCCAAGGCGATCGCGCTTGCGACCACTGCCGTCTTCACCGCGACCAGCCTCGCGCCCGC
GTTCGCCGGCGCGGCGACCACCACGCCGATCGAGCACGTCATCATCATCGTCGGCGAGAACCACACCTTCGACAACCTGT
TCGGCACCTACAAGCCCAAGGCCGACCAGAGCATCGACAACCTGCTCAGCAAGGGCATCGTCAACGAGGACGGCACGCCC
GGTCCGCATTTCAAGAAGGCCGAGCAGCGCATCGGCCGTGACGAGGTGCGCTATAGCGCCGAGACCGCATCGAGCGGCGC
CTACGCCACGCTGCCACAACCCTACACCACCTACGGCATCGGCCTGCCGCAGAACGTGCTCGACACGCGTTTCCCCGCCA
ATCTCCCCAACGGGCCGTATCAGATCTCCAAATACGTGCCCTACGCCGCCTACACCGGCGATCCGGTGCATCGCTTCTTT
CAGATGTGGCAGGACATCGACGGCGGCAAGCACGACAAGTTCGTGTGGGTCGAGCAGTCCATCGGCACCGGCTCGAACGG
CAAGCCGTACCCCGCCGGCGGCTTCAATCCGATGGAAGGCGCCATTTCGATGGGCTTCTACAACATGAACCCGTTCACCG
ATGCGAGCGGCAAGGCCCAGCCCGGCGACGCGCCGTTTTTCAAGAAGCTGGCTGACGACTACGCGATCAGCGACAACTAC
CACCAGGCGGTCATGGGCGGCACGGGTGCCAACTTCCAGGCCCTCGTGACCGGCCACGCGGCGTTCTTCACCAATCCCGA
GACGCTGAATGGCGCGCCTGCCGTGCCCTACGCCAACCAGATCGAAAACCCCGACCCCGTTCCCGGCACCAACAACTACT
ACAAGCAGGACGGCTACAGCGGCGGCTCCTACGTCAACTGCTCGGATCCGAGCGCGCCGGGTGTCTCCGCCATCAACGAG
CAGCTGTTCAAGAACGGCGTCCACAACAACAATTGCGCGCCGAACCACTATTATCTGGTCAACAATTACAGCATGTTCTG
GAACCAGACCAGCGCCAAGCCGAACGCGCTGGGCTCGGACAAGTTCGTGCTGCCGCCGCAGAGCGCGCCGACGATCGCCG
ACGTCATGACCGCCAAGGGCGTGTCCTGGAAATACTACAGCGCCGACCGCGGCGACGACGCCACCACTTTCGCCACCAGC
GTCGACGGCGTGCCGCTGCTGTTCCACTCCTATTGCGGCATCTGCGACCCGCTGACCGGTTTCATCAAGGTCATGACGAA
CCCGACCGAGGAAGCCAAGCTGCAGAACTACGGCGCCTTCGTGAAGGACGTGCAGAACAACACGCTGCCGGCGGTGTCGT
TCGTGCGTCCGTTCGAGGCGCTGGCCGGACATCCCGCCGACTCGACCACGGACCTCTACGAGAAGTTCCTCGAGGCCCTG
ATCAACCGCGTCAAGGCCAACCCGCAACTCTGGGCGAAGACGGCGATCTTCATCACCACCGATGAAGGCGGCGGCTATTA
CGACTCCGGCTACGTCCAGCCCGTCGACTTCCTCGGCGACGGCACCCGCATTCCCTTCATTCTGGTCTCGCCGCTGGCCA
AGAAGGGTCATGTCGACCACACCTATTACGACCACGTCTCGCTCTTGAAGTTCATCGAGCGCAACTGGCGGCTGCCCGCC
ATCTCCGCCGTCAGCCGCGACCGGCTGCCGAACCCGATCCATGATCGGGACGACAATCGCTACGTGCCGAAGAACCGGCC
GGCGATCGGCGACCTGATGAACCTGTTCGTGTTCGCCGGCGATGACGACGACCACGACGGCGGCTGGCACCATCACCACG
ACCACGATCGGGACGACGATCGCTGA

Upstream 100 bases:

>100_bases
TGACCGACACCGCATTGCAATTTGTTGCTGCGATGTTTTGACGCAGGCGCCCGCTCAGCAGCGGCACGCGCCAGCCACAC
CCACTCCGTCCGGAGATGTC

Downstream 100 bases:

>100_bases
TTGATCGCTTCCGTCAGCGTAGCGACGGTACGAGCAGGACAGGCCCGCCGCACTCTGTTGCGGCGGGCCTCTTACTTCGG
GACCGGCGGAGCGACGTACC

Product: putative phosphoesterase familiy protein signal peptide

Products: NA

Alternate protein names: Heat-labile hemolysin; PLC-H; Phosphatidylcholine cholinephosphohydrolase [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTRTVIRSKAIALATTAVFTATSLAPAFAGAATTTPIEHVIIIVGENHTFDNLFGTYKPKADQSIDNLLSKGIVNEDGTP
GPHFKKAEQRIGRDEVRYSAETASSGAYATLPQPYTTYGIGLPQNVLDTRFPANLPNGPYQISKYVPYAAYTGDPVHRFF
QMWQDIDGGKHDKFVWVEQSIGTGSNGKPYPAGGFNPMEGAISMGFYNMNPFTDASGKAQPGDAPFFKKLADDYAISDNY
HQAVMGGTGANFQALVTGHAAFFTNPETLNGAPAVPYANQIENPDPVPGTNNYYKQDGYSGGSYVNCSDPSAPGVSAINE
QLFKNGVHNNNCAPNHYYLVNNYSMFWNQTSAKPNALGSDKFVLPPQSAPTIADVMTAKGVSWKYYSADRGDDATTFATS
VDGVPLLFHSYCGICDPLTGFIKVMTNPTEEAKLQNYGAFVKDVQNNTLPAVSFVRPFEALAGHPADSTTDLYEKFLEAL
INRVKANPQLWAKTAIFITTDEGGGYYDSGYVQPVDFLGDGTRIPFILVSPLAKKGHVDHTYYDHVSLLKFIERNWRLPA
ISAVSRDRLPNPIHDRDDNRYVPKNRPAIGDLMNLFVFAGDDDDHDGGWHHHHDHDRDDDR

Sequences:

>Translated_621_residues
MTRTVIRSKAIALATTAVFTATSLAPAFAGAATTTPIEHVIIIVGENHTFDNLFGTYKPKADQSIDNLLSKGIVNEDGTP
GPHFKKAEQRIGRDEVRYSAETASSGAYATLPQPYTTYGIGLPQNVLDTRFPANLPNGPYQISKYVPYAAYTGDPVHRFF
QMWQDIDGGKHDKFVWVEQSIGTGSNGKPYPAGGFNPMEGAISMGFYNMNPFTDASGKAQPGDAPFFKKLADDYAISDNY
HQAVMGGTGANFQALVTGHAAFFTNPETLNGAPAVPYANQIENPDPVPGTNNYYKQDGYSGGSYVNCSDPSAPGVSAINE
QLFKNGVHNNNCAPNHYYLVNNYSMFWNQTSAKPNALGSDKFVLPPQSAPTIADVMTAKGVSWKYYSADRGDDATTFATS
VDGVPLLFHSYCGICDPLTGFIKVMTNPTEEAKLQNYGAFVKDVQNNTLPAVSFVRPFEALAGHPADSTTDLYEKFLEAL
INRVKANPQLWAKTAIFITTDEGGGYYDSGYVQPVDFLGDGTRIPFILVSPLAKKGHVDHTYYDHVSLLKFIERNWRLPA
ISAVSRDRLPNPIHDRDDNRYVPKNRPAIGDLMNLFVFAGDDDDHDGGWHHHHDHDRDDDR
>Mature_620_residues
TRTVIRSKAIALATTAVFTATSLAPAFAGAATTTPIEHVIIIVGENHTFDNLFGTYKPKADQSIDNLLSKGIVNEDGTPG
PHFKKAEQRIGRDEVRYSAETASSGAYATLPQPYTTYGIGLPQNVLDTRFPANLPNGPYQISKYVPYAAYTGDPVHRFFQ
MWQDIDGGKHDKFVWVEQSIGTGSNGKPYPAGGFNPMEGAISMGFYNMNPFTDASGKAQPGDAPFFKKLADDYAISDNYH
QAVMGGTGANFQALVTGHAAFFTNPETLNGAPAVPYANQIENPDPVPGTNNYYKQDGYSGGSYVNCSDPSAPGVSAINEQ
LFKNGVHNNNCAPNHYYLVNNYSMFWNQTSAKPNALGSDKFVLPPQSAPTIADVMTAKGVSWKYYSADRGDDATTFATSV
DGVPLLFHSYCGICDPLTGFIKVMTNPTEEAKLQNYGAFVKDVQNNTLPAVSFVRPFEALAGHPADSTTDLYEKFLEALI
NRVKANPQLWAKTAIFITTDEGGGYYDSGYVQPVDFLGDGTRIPFILVSPLAKKGHVDHTYYDHVSLLKFIERNWRLPAI
SAVSRDRLPNPIHDRDDNRYVPKNRPAIGDLMNLFVFAGDDDDHDGGWHHHHDHDRDDDR

Specific function: Hydrolyzes sphingomyelin in addition to phosphatidylcholine [H]

COG id: COG3511

COG function: function code M; Phospholipase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial phospholipase C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007312
- InterPro:   IPR008475
- InterPro:   IPR017767
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05506 DUF756; PF04185 Phosphoesterase [H]

EC number: =3.1.4.3 [H]

Molecular weight: Translated: 68032; Mature: 67901

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTVIRSKAIALATTAVFTATSLAPAFAGAATTTPIEHVIIIVGENHTFDNLFGTYKPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCC
ADQSIDNLLSKGIVNEDGTPGPHFKKAEQRIGRDEVRYSAETASSGAYATLPQPYTTYGI
CHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHCCHHCCCCCCEEECCCCCCEECC
GLPQNVLDTRFPANLPNGPYQISKYVPYAAYTGDPVHRFFQMWQDIDGGKHDKFVWVEQS
CCCHHHHHCCCCCCCCCCCEEHHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEC
IGTGSNGKPYPAGGFNPMEGAISMGFYNMNPFTDASGKAQPGDAPFFKKLADDYAISDNY
CCCCCCCCCCCCCCCCCCCHHEEECEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
HQAVMGGTGANFQALVTGHAAFFTNPETLNGAPAVPYANQIENPDPVPGTNNYYKQDGYS
HHHEECCCCCCEEEEEECCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCC
GGSYVNCSDPSAPGVSAINEQLFKNGVHNNNCAPNHYYLVNNYSMFWNQTSAKPNALGSD
CCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCC
KFVLPPQSAPTIADVMTAKGVSWKYYSADRGDDATTFATSVDGVPLLFHSYCGICDPLTG
CEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHH
FIKVMTNPTEEAKLQNYGAFVKDVQNNTLPAVSFVRPFEALAGHPADSTTDLYEKFLEAL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
INRVKANPQLWAKTAIFITTDEGGGYYDSGYVQPVDFLGDGTRIPFILVSPLAKKGHVDH
HHHHCCCCCEEEEEEEEEEECCCCCEECCCCCCCHHHCCCCCCCCEEEECCHHHCCCCCC
TYYDHVSLLKFIERNWRLPAISAVSRDRLPNPIHDRDDNRYVPKNRPAIGDLMNLFVFAG
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHEEEEEEC
DDDDHDGGWHHHHDHDRDDDR
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRTVIRSKAIALATTAVFTATSLAPAFAGAATTTPIEHVIIIVGENHTFDNLFGTYKPK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCC
ADQSIDNLLSKGIVNEDGTPGPHFKKAEQRIGRDEVRYSAETASSGAYATLPQPYTTYGI
CHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHCCHHCCCCCCEEECCCCCCEECC
GLPQNVLDTRFPANLPNGPYQISKYVPYAAYTGDPVHRFFQMWQDIDGGKHDKFVWVEQS
CCCHHHHHCCCCCCCCCCCEEHHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEC
IGTGSNGKPYPAGGFNPMEGAISMGFYNMNPFTDASGKAQPGDAPFFKKLADDYAISDNY
CCCCCCCCCCCCCCCCCCCHHEEECEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
HQAVMGGTGANFQALVTGHAAFFTNPETLNGAPAVPYANQIENPDPVPGTNNYYKQDGYS
HHHEECCCCCCEEEEEECCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCC
GGSYVNCSDPSAPGVSAINEQLFKNGVHNNNCAPNHYYLVNNYSMFWNQTSAKPNALGSD
CCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCC
KFVLPPQSAPTIADVMTAKGVSWKYYSADRGDDATTFATSVDGVPLLFHSYCGICDPLTG
CEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHH
FIKVMTNPTEEAKLQNYGAFVKDVQNNTLPAVSFVRPFEALAGHPADSTTDLYEKFLEAL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
INRVKANPQLWAKTAIFITTDEGGGYYDSGYVQPVDFLGDGTRIPFILVSPLAKKGHVDH
HHHHCCCCCEEEEEEEEEEECCCCCEECCCCCCCHHHCCCCCCCCEEEECCHHHCCCCCC
TYYDHVSLLKFIERNWRLPAISAVSRDRLPNPIHDRDDNRYVPKNRPAIGDLMNLFVFAG
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHEEEEEEC
DDDDHDGGWHHHHDHDRDDDR
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3087958; 10984043 [H]