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The map label for this gene is gltK [H]

Identifier: 146342963

GI number: 146342963

Start: 6369854

End: 6370546

Strand: Reverse

Name: gltK [H]

Synonym: BRADO6146

Alternate gene names: 146342963

Gene position: 6370546-6369854 (Counterclockwise)

Preceding gene: 146342964

Following gene: 146342962

Centisome position: 85.44

GC content: 63.49

Gene sequence:

>693_bases
ATGCTGGCCAATTTCGACTTCGACGTCATCCGCCGCTCGCTGAGCTACCTGTTCATCGACGGCATGACTTTCACGCTGAC
GCTGACCGCGCTGTCGGCGTTCGGCGGTCTCGTGTTCGGCACCTTGATCGCGATGATGCGGCTGTCGGGCTATCGCGTGA
TGGGCTGGATCGCCGGGCTCTATGTCGACTTCATGCGCTCGCTGCCGCTGGTGCTGGTGATCTTCTGGTTCTACTTCCTG
GTCCCCTATATCGGGCAGTGGATCACCGGCTCGTCCAGGCCGATCAAGGTCGGCGCCTTCGCCTCGTCCTTGATCACCTT
CATCATGTTCGAGGCGGCGTATTTCTCCGAGATCATGCGGGCCGGCATCCAGTCGATCTCGCGGGGACAGCCGGCCGCGG
CCTCGGCGCTCGGCCTCACTTACGCGCAGACCATGCGCTACGTCGTGCTGCCGCAAGCGTTCCGCAACATGCTGCCGGTG
CTGCTGACCCAGACAATCGTGCTGTTCCAGGACACCTCGCTGGTCTACGTGCTCTCGATCCCGGACTTCCTCGGCGCGGC
GTCGAAGGTGGCGCAGCGCGACGGCCGGCTGGTCGAGATGTACCTGTTCGCCGCATTGGTCTACTTCACCATCTCCTGCA
TCGCGTCCTACGGCGTCCGCCGCCTGCAGTCGCGCATCGCCATCATCAGGTAG

Upstream 100 bases:

>100_bases
GCGACCCTGATGTATCTCGTCATCAACATCATCGTCGTGATCGGCATGCGCCTGCTGGAGCGCGCGGTGGCGATCCCTGG
CTACATCACGGGCAAATGAG

Downstream 100 bases:

>100_bases
TCGGCTCCCATGATCGAAATCAGCCACGTCAACAAATGGTACAGCCCGACCTTCCAGGTGCTGAAGGACTGCACCACGTC
CGTCGCCAAGGGCGAGGTCG

Product: glutamate/aspartate ABC transporter permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLANFDFDVIRRSLSYLFIDGMTFTLTLTALSAFGGLVFGTLIAMMRLSGYRVMGWIAGLYVDFMRSLPLVLVIFWFYFL
VPYIGQWITGSSRPIKVGAFASSLITFIMFEAAYFSEIMRAGIQSISRGQPAAASALGLTYAQTMRYVVLPQAFRNMLPV
LLTQTIVLFQDTSLVYVLSIPDFLGAASKVAQRDGRLVEMYLFAALVYFTISCIASYGVRRLQSRIAIIR

Sequences:

>Translated_230_residues
MLANFDFDVIRRSLSYLFIDGMTFTLTLTALSAFGGLVFGTLIAMMRLSGYRVMGWIAGLYVDFMRSLPLVLVIFWFYFL
VPYIGQWITGSSRPIKVGAFASSLITFIMFEAAYFSEIMRAGIQSISRGQPAAASALGLTYAQTMRYVVLPQAFRNMLPV
LLTQTIVLFQDTSLVYVLSIPDFLGAASKVAQRDGRLVEMYLFAALVYFTISCIASYGVRRLQSRIAIIR
>Mature_230_residues
MLANFDFDVIRRSLSYLFIDGMTFTLTLTALSAFGGLVFGTLIAMMRLSGYRVMGWIAGLYVDFMRSLPLVLVIFWFYFL
VPYIGQWITGSSRPIKVGAFASSLITFIMFEAAYFSEIMRAGIQSISRGQPAAASALGLTYAQTMRYVVLPQAFRNMLPV
LLTQTIVLFQDTSLVYVLSIPDFLGAASKVAQRDGRLVEMYLFAALVYFTISCIASYGVRRLQSRIAIIR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=224, Percent_Identity=53.125, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1788226, Length=204, Percent_Identity=35.2941176470588, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787030, Length=226, Percent_Identity=30.5309734513274, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87082239, Length=211, Percent_Identity=30.8056872037915, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786874, Length=198, Percent_Identity=28.7878787878788, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787087, Length=230, Percent_Identity=27.3913043478261, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI48994930, Length=166, Percent_Identity=29.5180722891566, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788645, Length=207, Percent_Identity=25.1207729468599, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25733; Mature: 25733

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANFDFDVIRRSLSYLFIDGMTFTLTLTALSAFGGLVFGTLIAMMRLSGYRVMGWIAGL
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YVDFMRSLPLVLVIFWFYFLVPYIGQWITGSSRPIKVGAFASSLITFIMFEAAYFSEIMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
AGIQSISRGQPAAASALGLTYAQTMRYVVLPQAFRNMLPVLLTQTIVLFQDTSLVYVLSI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
PDFLGAASKVAQRDGRLVEMYLFAALVYFTISCIASYGVRRLQSRIAIIR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLANFDFDVIRRSLSYLFIDGMTFTLTLTALSAFGGLVFGTLIAMMRLSGYRVMGWIAGL
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YVDFMRSLPLVLVIFWFYFLVPYIGQWITGSSRPIKVGAFASSLITFIMFEAAYFSEIMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
AGIQSISRGQPAAASALGLTYAQTMRYVVLPQAFRNMLPVLLTQTIVLFQDTSLVYVLSI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
PDFLGAASKVAQRDGRLVEMYLFAALVYFTISCIASYGVRRLQSRIAIIR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]