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The map label for this gene is coxS [H]

Identifier: 146342850

GI number: 146342850

Start: 6254141

End: 6254641

Strand: Reverse

Name: coxS [H]

Synonym: BRADO6030

Alternate gene names: 146342850

Gene position: 6254641-6254141 (Counterclockwise)

Preceding gene: 146342851

Following gene: 146342849

Centisome position: 83.88

GC content: 63.27

Gene sequence:

>501_bases
ATGCCCAAAACCCACGTCACGATGAAGGTGAATGGCAGCGAGGTCGAGGGCCTCGCCGAGCCGCGCACTTTGCTGGTCCA
CTTCCTGCGCGAGCAGGCGCAGCTCACCGGCACGCATATCGGCTGCGAGACCAGCCATTGCGGCGCCTGCACCGTCGATA
TCGACGGCATGAGCGTAAAGAGCTGCACCATGCTCGCGGTGCAGGCCAATGGCGCCGAGATCACAACGATCGAAGGCATG
GCCAACGCCGACGGCACCCTGTCGCCGCTGCAGGAAGGCTTTCGCATGATGCACGGCCTGCAATGCGGCTTCTGCACGCC
CGGCATGATTTTGCGCGCGCATCGGCTGCTGAAGGAAAATCCGTCGCCGACCGAAGCCGAGATCCGCGCCGGCATCTCCG
GCAACATCTGCCGCTGCACCGGCTATCAGAACATCGTCAAGGCGATCCAATACGCCGCCGCCAAGATCAACGGCGTTGAA
TTCCAGGAGGCCGCGGAATGA

Upstream 100 bases:

>100_bases
TGGCTGACCCTCTCCCCGTGAACAACGCGGAGAGGGAGCCTCCCGACACCGCCGCTGATAGCTGGCCCAAAGTTCGAAGA
AGATTTCCAGGGAGCACCGA

Downstream 100 bases:

>100_bases
ACGACATGACTCCCACGCGGGAACAACGCGAAGCCGCCCTCGAAGGCATGGGCTGCCGGCGCAAGCGCGTCGAGGACATC
CGCTTCACGCAAGGCAAGGG

Product: carbon-monoxide dehydrogenase small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MPKTHVTMKVNGSEVEGLAEPRTLLVHFLREQAQLTGTHIGCETSHCGACTVDIDGMSVKSCTMLAVQANGAEITTIEGM
ANADGTLSPLQEGFRMMHGLQCGFCTPGMILRAHRLLKENPSPTEAEIRAGISGNICRCTGYQNIVKAIQYAAAKINGVE
FQEAAE

Sequences:

>Translated_166_residues
MPKTHVTMKVNGSEVEGLAEPRTLLVHFLREQAQLTGTHIGCETSHCGACTVDIDGMSVKSCTMLAVQANGAEITTIEGM
ANADGTLSPLQEGFRMMHGLQCGFCTPGMILRAHRLLKENPSPTEAEIRAGISGNICRCTGYQNIVKAIQYAAAKINGVE
FQEAAE
>Mature_165_residues
PKTHVTMKVNGSEVEGLAEPRTLLVHFLREQAQLTGTHIGCETSHCGACTVDIDGMSVKSCTMLAVQANGAEITTIEGMA
NADGTLSPLQEGFRMMHGLQCGFCTPGMILRAHRLLKENPSPTEAEIRAGISGNICRCTGYQNIVKAIQYAAAKINGVEF
QEAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=164, Percent_Identity=37.1951219512195, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI71773480, Length=156, Percent_Identity=35.2564102564103, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=43.3734939759036, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=45.4545454545455, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=165, Percent_Identity=40.6060606060606, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=160, Percent_Identity=35.625, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=169, Percent_Identity=34.3195266272189, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17737937, Length=161, Percent_Identity=35.4037267080745, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24647199, Length=142, Percent_Identity=40.1408450704225, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24647197, Length=166, Percent_Identity=32.5301204819277, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24647201, Length=138, Percent_Identity=39.1304347826087, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647193, Length=164, Percent_Identity=35.3658536585366, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24647195, Length=166, Percent_Identity=32.5301204819277, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17751; Mature: 17619

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTHVTMKVNGSEVEGLAEPRTLLVHFLREQAQLTGTHIGCETSHCGACTVDIDGMSVK
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
SCTMLAVQANGAEITTIEGMANADGTLSPLQEGFRMMHGLQCGFCTPGMILRAHRLLKEN
CEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
PSPTEAEIRAGISGNICRCTGYQNIVKAIQYAAAKINGVEFQEAAE
CCCCHHHEECCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure 
PKTHVTMKVNGSEVEGLAEPRTLLVHFLREQAQLTGTHIGCETSHCGACTVDIDGMSVK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
SCTMLAVQANGAEITTIEGMANADGTLSPLQEGFRMMHGLQCGFCTPGMILRAHRLLKEN
CEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
PSPTEAEIRAGISGNICRCTGYQNIVKAIQYAAAKINGVEFQEAAE
CCCCHHHEECCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]