Click here to switch to the map view.

The map label for this gene is coxL [H]

Identifier: 146342849

GI number: 146342849

Start: 6251724

End: 6254144

Strand: Reverse

Name: coxL [H]

Synonym: BRADO6029

Alternate gene names: 146342849

Gene position: 6254144-6251724 (Counterclockwise)

Preceding gene: 146342850

Following gene: 146342848

Centisome position: 83.87

GC content: 64.64

Gene sequence:

>2421_bases
ATGAACGACATGACTCCCACGCGGGAACAACGCGAAGCCGCCCTCGAAGGCATGGGCTGCCGGCGCAAGCGCGTCGAGGA
CATCCGCTTCACGCAAGGCAAGGGCAATTACGTCGACGACGTCAAGCTGCCGGGCATGCTGCATGGCGACTTCGTGCGCT
CGCCGCATGCGCATGCCCGGGTCAAGGCGATCCACACCGAGGAGGCGCTCAAGGTGCCGGGCGTGCTCGCGGTGATCACC
GCCGAGACCTTGAAGACCGTCAACCTCGCCTGGATGCCGACCCTCGCGGGCGACGTGCAGATGGTGCTCGCCGACGGCAA
GGTGCTGTTCCAGAACCAGGAGGTCGCTTTCGTCGTCGCCACCGACCGCTACGCCGCCGATGACGGCGTCTCGAAGGTGG
TCGTCGACTATGAGCCGCTGCCGGTGCTGGTCGATCCGTTCAAGGCGATGGACCCGGATGCGCCGGTCCTGCGCGAGGAC
CTCGCCGGCAAGACCACAGGCGCGCATGGGCCGCGCAAGCATCACAACCACATCTTCGAATGGAGCGTCGGCGACAAGGA
GCTGACGGATGCCGCGTTCAAGAAGGCGGATGTGACGATCAAGGAGATGATCTCCTATCACCGCACCCATCCGTCGCCGC
TCGAGACCTGTCAGTGCGTCTGCTCGTTCGACAAGATCAAGGGCGAGCTGACGATCTGGGGAACGTTCCAGGCGCCGCAT
GTGATCCGCACCGTGGTGTCGCTGATCGCGAAACTGCCGGAGCAGAAGATTCACGTCATCGCGCCGGATATCGGCGGCGG
CTTCGGCAACAAGGTCGGCGCCTATCCCGGCTATATCTGTGCGGCGGTGGCCTCGATCGTCACCGGCAAGCCGGTGAAAT
GGGTCGAGGACCGCATCGAGAACCTCACCGCGACCGCGTTCGCGCGCGACTATCACATGACGACCGAGATCGCCGCGACC
AAGGACGGCAAGGTCACCGGCCTGCGCGTCCACGTGCTGGCCGATCACGGTGGCTTCGATGCCTGCGCCGATCCGTCGAA
ATGGCCGGCCGGCTTCTTCAACATCGTCACCGGCTCGTATGATTTCCCGGTTGCGCATCTCGCGGTGGACGGCGTCTACA
CCAACAAGGCGCCGGGCGGGGTCGCCTACCGCTGCTCGTTCCGCGTCACCGAGGCGGCCTATTGCATCGAGCGCGCGATG
GACATTTTGGCGCAAAAGCTCGGCATGGATCCGGCCGAACTGCGGCTGAAGAACTTCGTCAAGCCGGAGCAGTTCCCCTA
TCACTCAGCGCTCGGCTGGGAATACGATTCCGGCGACTATCACACCGCCATGCGAAAGATGATGGAGACGGTCGACTACG
CCGGTCTGCGCAAGGAGCAGGCCGAGAAGCGCGCCGCCTTCAAGCGCGGCGAGACGCGGGAGATCATGGGCATCGGCATC
GGCTTCTTCACCGAGATCGTCGGCGCCGGCCCGTCCAAGAACTGCGACATTCTCGGCATCGCGATGTTCGATTCCTGCGA
GATCCGGCTGCACCCGACCGGCGCCGGCATCGCGCGCATGGGCACCAAGAGCCAGGGTCAGGGCCACGAGACCACCTGGG
CGCAGATCATCGCCAGCGAGATCGGCATTCCCGCCGACAACATCATGGTCGAGGAGGGCAACACCGATACCGCGCCTTAC
GGCTTGGGCACCTACGGCTCGCGCTCGACGCCGGTCGCCGGCGCGGCCATCGCCATGGCGGCTCGGAAGATCAAGGCCAA
GGCGCAGATGATCGCGGCCTACAAGCTCGAGGTCCACGAGGACGACCTCGAATGGGACATCGACGGCTTCCGGGTCAAGG
GCCTGCCGGAGAAGGCGATGTCGATGAAGGACATCTGCTGGGCCGCATATAACTCGGTTCCTCCCGGCATGGAGCCGGGA
CTGGAGGCGGTGAGCTACTACGATCCGCCCAACATGACCTATCCGTTCGGCGCGTATCTCTGCGTGATGGACATCGATGT
CGACACCGGCGTGTACAAGGTCCGGCGCTTCTACGCGCTCGACGATTGCGGCACCCGCATCAACCCGATGATCATTGAGG
GCCAGGTCCATGGCGGCCTCACCGAAGCCTTCGCCATCGCGATGGGCCAGGAGATCCGCTACGATGCCGAGGGCAACGTC
GTCACCGGCTCGTTCATGGATTTCTTCATGCCGACCGCGGTGGAGACGCCGCATTGGGAGACCGACTACACGGTGACTCC
GTCGCCGCACCACCCGATCGGCGCCAAGGGTGTCGGCGAAAGCCCCAATGTCGGCGGCGTGCCGGCGTTCTCGAATGCGG
TGAACGACGCCTTCTCGTTCCTCGGCGCCACCCACATCCAGATGCCCCACGACTTCTGGCGCAACTGGCAGGCCGCGAAG
ACTTTGGGTGTTGTGGCGTAG

Upstream 100 bases:

>100_bases
CCGGCAACATCTGCCGCTGCACCGGCTATCAGAACATCGTCAAGGCGATCCAATACGCCGCCGCCAAGATCAACGGCGTT
GAATTCCAGGAGGCCGCGGA

Downstream 100 bases:

>100_bases
ACTGACCTCTGGCTCCACCGTCATTGCGAGGAGCGAAGCGACGACCTGTCCGCCATAGCCCGAAGGGCGACGGCGGAAGC
AATCCAGAGTCCTACCCGAG

Product: carbon monoxide dehydrogenase large chain

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MNDMTPTREQREAALEGMGCRRKRVEDIRFTQGKGNYVDDVKLPGMLHGDFVRSPHAHARVKAIHTEEALKVPGVLAVIT
AETLKTVNLAWMPTLAGDVQMVLADGKVLFQNQEVAFVVATDRYAADDGVSKVVVDYEPLPVLVDPFKAMDPDAPVLRED
LAGKTTGAHGPRKHHNHIFEWSVGDKELTDAAFKKADVTIKEMISYHRTHPSPLETCQCVCSFDKIKGELTIWGTFQAPH
VIRTVVSLIAKLPEQKIHVIAPDIGGGFGNKVGAYPGYICAAVASIVTGKPVKWVEDRIENLTATAFARDYHMTTEIAAT
KDGKVTGLRVHVLADHGGFDACADPSKWPAGFFNIVTGSYDFPVAHLAVDGVYTNKAPGGVAYRCSFRVTEAAYCIERAM
DILAQKLGMDPAELRLKNFVKPEQFPYHSALGWEYDSGDYHTAMRKMMETVDYAGLRKEQAEKRAAFKRGETREIMGIGI
GFFTEIVGAGPSKNCDILGIAMFDSCEIRLHPTGAGIARMGTKSQGQGHETTWAQIIASEIGIPADNIMVEEGNTDTAPY
GLGTYGSRSTPVAGAAIAMAARKIKAKAQMIAAYKLEVHEDDLEWDIDGFRVKGLPEKAMSMKDICWAAYNSVPPGMEPG
LEAVSYYDPPNMTYPFGAYLCVMDIDVDTGVYKVRRFYALDDCGTRINPMIIEGQVHGGLTEAFAIAMGQEIRYDAEGNV
VTGSFMDFFMPTAVETPHWETDYTVTPSPHHPIGAKGVGESPNVGGVPAFSNAVNDAFSFLGATHIQMPHDFWRNWQAAK
TLGVVA

Sequences:

>Translated_806_residues
MNDMTPTREQREAALEGMGCRRKRVEDIRFTQGKGNYVDDVKLPGMLHGDFVRSPHAHARVKAIHTEEALKVPGVLAVIT
AETLKTVNLAWMPTLAGDVQMVLADGKVLFQNQEVAFVVATDRYAADDGVSKVVVDYEPLPVLVDPFKAMDPDAPVLRED
LAGKTTGAHGPRKHHNHIFEWSVGDKELTDAAFKKADVTIKEMISYHRTHPSPLETCQCVCSFDKIKGELTIWGTFQAPH
VIRTVVSLIAKLPEQKIHVIAPDIGGGFGNKVGAYPGYICAAVASIVTGKPVKWVEDRIENLTATAFARDYHMTTEIAAT
KDGKVTGLRVHVLADHGGFDACADPSKWPAGFFNIVTGSYDFPVAHLAVDGVYTNKAPGGVAYRCSFRVTEAAYCIERAM
DILAQKLGMDPAELRLKNFVKPEQFPYHSALGWEYDSGDYHTAMRKMMETVDYAGLRKEQAEKRAAFKRGETREIMGIGI
GFFTEIVGAGPSKNCDILGIAMFDSCEIRLHPTGAGIARMGTKSQGQGHETTWAQIIASEIGIPADNIMVEEGNTDTAPY
GLGTYGSRSTPVAGAAIAMAARKIKAKAQMIAAYKLEVHEDDLEWDIDGFRVKGLPEKAMSMKDICWAAYNSVPPGMEPG
LEAVSYYDPPNMTYPFGAYLCVMDIDVDTGVYKVRRFYALDDCGTRINPMIIEGQVHGGLTEAFAIAMGQEIRYDAEGNV
VTGSFMDFFMPTAVETPHWETDYTVTPSPHHPIGAKGVGESPNVGGVPAFSNAVNDAFSFLGATHIQMPHDFWRNWQAAK
TLGVVA
>Mature_806_residues
MNDMTPTREQREAALEGMGCRRKRVEDIRFTQGKGNYVDDVKLPGMLHGDFVRSPHAHARVKAIHTEEALKVPGVLAVIT
AETLKTVNLAWMPTLAGDVQMVLADGKVLFQNQEVAFVVATDRYAADDGVSKVVVDYEPLPVLVDPFKAMDPDAPVLRED
LAGKTTGAHGPRKHHNHIFEWSVGDKELTDAAFKKADVTIKEMISYHRTHPSPLETCQCVCSFDKIKGELTIWGTFQAPH
VIRTVVSLIAKLPEQKIHVIAPDIGGGFGNKVGAYPGYICAAVASIVTGKPVKWVEDRIENLTATAFARDYHMTTEIAAT
KDGKVTGLRVHVLADHGGFDACADPSKWPAGFFNIVTGSYDFPVAHLAVDGVYTNKAPGGVAYRCSFRVTEAAYCIERAM
DILAQKLGMDPAELRLKNFVKPEQFPYHSALGWEYDSGDYHTAMRKMMETVDYAGLRKEQAEKRAAFKRGETREIMGIGI
GFFTEIVGAGPSKNCDILGIAMFDSCEIRLHPTGAGIARMGTKSQGQGHETTWAQIIASEIGIPADNIMVEEGNTDTAPY
GLGTYGSRSTPVAGAAIAMAARKIKAKAQMIAAYKLEVHEDDLEWDIDGFRVKGLPEKAMSMKDICWAAYNSVPPGMEPG
LEAVSYYDPPNMTYPFGAYLCVMDIDVDTGVYKVRRFYALDDCGTRINPMIIEGQVHGGLTEAFAIAMGQEIRYDAEGNV
VTGSFMDFFMPTAVETPHWETDYTVTPSPHHPIGAKGVGESPNVGGVPAFSNAVNDAFSFLGATHIQMPHDFWRNWQAAK
TLGVVA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=764, Percent_Identity=24.0837696335079, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI91823271, Length=787, Percent_Identity=24.1423125794155, Blast_Score=115, Evalue=2e-25,
Organism=Escherichia coli, GI1789230, Length=772, Percent_Identity=25.9067357512953, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789246, Length=797, Percent_Identity=25.5959849435383, Blast_Score=199, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17540638, Length=767, Percent_Identity=23.3376792698827, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24647199, Length=763, Percent_Identity=22.2804718217562, Blast_Score=107, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 88039; Mature: 88039

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMTPTREQREAALEGMGCRRKRVEDIRFTQGKGNYVDDVKLPGMLHGDFVRSPHAHAR
CCCCCCCHHHHHHHHHCCCCHHHHHHHCEEECCCCCCCCCCCCCCEECCHHHCCCCCCCE
VKAIHTEEALKVPGVLAVITAETLKTVNLAWMPTLAGDVQMVLADGKVLFQNQEVAFVVA
EEEEECHHHHCCCCEEEEEEHHHHHEEEEEEECCCCCCEEEEEECCEEEEECCCEEEEEE
TDRYAADDGVSKVVVDYEPLPVLVDPFKAMDPDAPVLREDLAGKTTGAHGPRKHHNHIFE
ECCCCCCCCCEEEEEECCCCCEEECCHHHCCCCCCHHHHHHCCCCCCCCCCHHHCCEEEE
WSVGDKELTDAAFKKADVTIKEMISYHRTHPSPLETCQCVCSFDKIKGELTIWGTFQAPH
EECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCH
VIRTVVSLIAKLPEQKIHVIAPDIGGGFGNKVGAYPGYICAAVASIVTGKPVKWVEDRIE
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
NLTATAFARDYHMTTEIAATKDGKVTGLRVHVLADHGGFDACADPSKWPAGFFNIVTGSY
HHHHHHHHHHHEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCC
DFPVAHLAVDGVYTNKAPGGVAYRCSFRVTEAAYCIERAMDILAQKLGMDPAELRLKNFV
CCCEEEEEECCEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
KPEQFPYHSALGWEYDSGDYHTAMRKMMETVDYAGLRKEQAEKRAAFKRGETREIMGIGI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECH
GFFTEIVGAGPSKNCDILGIAMFDSCEIRLHPTGAGIARMGTKSQGQGHETTWAQIIASE
HHHHHHHCCCCCCCCCEEEEEEECCEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHH
IGIPADNIMVEEGNTDTAPYGLGTYGSRSTPVAGAAIAMAARKIKAKAQMIAAYKLEVHE
HCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEC
DDLEWDIDGFRVKGLPEKAMSMKDICWAAYNSVPPGMEPGLEAVSYYDPPNMTYPFGAYL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCEEE
CVMDIDVDTGVYKVRRFYALDDCGTRINPMIIEGQVHGGLTEAFAIAMGQEIRYDAEGNV
EEEEECCCCCHHHHHHEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCCE
VTGSFMDFFMPTAVETPHWETDYTVTPSPHHPIGAKGVGESPNVGGVPAFSNAVNDAFSF
EECCHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LGATHIQMPHDFWRNWQAAKTLGVVA
HCCCEECCCHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MNDMTPTREQREAALEGMGCRRKRVEDIRFTQGKGNYVDDVKLPGMLHGDFVRSPHAHAR
CCCCCCCHHHHHHHHHCCCCHHHHHHHCEEECCCCCCCCCCCCCCEECCHHHCCCCCCCE
VKAIHTEEALKVPGVLAVITAETLKTVNLAWMPTLAGDVQMVLADGKVLFQNQEVAFVVA
EEEEECHHHHCCCCEEEEEEHHHHHEEEEEEECCCCCCEEEEEECCEEEEECCCEEEEEE
TDRYAADDGVSKVVVDYEPLPVLVDPFKAMDPDAPVLREDLAGKTTGAHGPRKHHNHIFE
ECCCCCCCCCEEEEEECCCCCEEECCHHHCCCCCCHHHHHHCCCCCCCCCCHHHCCEEEE
WSVGDKELTDAAFKKADVTIKEMISYHRTHPSPLETCQCVCSFDKIKGELTIWGTFQAPH
EECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCH
VIRTVVSLIAKLPEQKIHVIAPDIGGGFGNKVGAYPGYICAAVASIVTGKPVKWVEDRIE
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
NLTATAFARDYHMTTEIAATKDGKVTGLRVHVLADHGGFDACADPSKWPAGFFNIVTGSY
HHHHHHHHHHHEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCC
DFPVAHLAVDGVYTNKAPGGVAYRCSFRVTEAAYCIERAMDILAQKLGMDPAELRLKNFV
CCCEEEEEECCEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
KPEQFPYHSALGWEYDSGDYHTAMRKMMETVDYAGLRKEQAEKRAAFKRGETREIMGIGI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECH
GFFTEIVGAGPSKNCDILGIAMFDSCEIRLHPTGAGIARMGTKSQGQGHETTWAQIIASE
HHHHHHHCCCCCCCCCEEEEEEECCEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHH
IGIPADNIMVEEGNTDTAPYGLGTYGSRSTPVAGAAIAMAARKIKAKAQMIAAYKLEVHE
HCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEC
DDLEWDIDGFRVKGLPEKAMSMKDICWAAYNSVPPGMEPGLEAVSYYDPPNMTYPFGAYL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCEEE
CVMDIDVDTGVYKVRRFYALDDCGTRINPMIIEGQVHGGLTEAFAIAMGQEIRYDAEGNV
EEEEECCCCCHHHHHHEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCCE
VTGSFMDFFMPTAVETPHWETDYTVTPSPHHPIGAKGVGESPNVGGVPAFSNAVNDAFSF
EECCHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LGATHIQMPHDFWRNWQAAKTLGVVA
HCCCEECCCHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]