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The map label for this gene is engD [H]

Identifier: 146342829

GI number: 146342829

Start: 6235006

End: 6236103

Strand: Direct

Name: engD [H]

Synonym: BRADO6008

Alternate gene names: 146342829

Gene position: 6235006-6236103 (Clockwise)

Preceding gene: 146342828

Following gene: 146342831

Centisome position: 83.62

GC content: 66.12

Gene sequence:

>1098_bases
ATGGGATTCAAATGCGGGATCGTCGGTCTGCCCAACGTCGGCAAGTCGACGCTGTTCAACGCGCTGACGGAGACGGCGGC
GGCGCAGGCGGCGAACTATCCGTTCTGCACCATCGAGCCGAATGTCGGCGAGGTCGCCGTGCCCGATCCCCGGCTGGAAA
AGCTTGCGGCGATCGCCAAGTCCGGCCAGATCATTCCGACCAGGCTGACCTTCGTCGACATCGCGGGCCTGGTGCGGGGC
GCCTCCAAGGGTGAAGGCCTGGGCAACCAGTTCCTCGCCAACATTCGCGAGGTCGACGCGATCGCGCATGTCGTGCGCTG
CTTCGAGGATTCCGACATCACCCATGTCGAGGGCAAGATCGCCCCGTTGGCCGACATCGAGACTATCGAGACCGAGCTGA
TGCTGGCCGATCTCGACAGCCTCGAGAAGCGGGTCGACAATCTGGCGAAGAAGGCCAAGGGCGGCGACAAGGACGCCAAG
GAGCAGCACGATCTCGTCACCCGCGCGCTGGTGCTGCTGCGCGACGGCAAGCCGGCGCGGCTGCTCGAGCGCAAGCCCGA
GGAGGAGCGCGCCTTCGGCATGCTCGGACTCTTGAGCTCAAAGCCGGTGCTGTACGTCTGCAACGTCGAGGAAGGCTCGG
CCAAGGACGGCAACAGCTTCTCGCAGGCGGTGTTCGCCCGCGCCAAGGAGGAAGGCGCGATCGCGGTGGTGATCTCGGCC
AAGATCGAGTCGGAGATCGCGACCCTGTCGCGCGAGGAGCGCGTCGATTTTCTCGAGACGCTCGGGCTCGAAGAGGCCGG
CCTCGACCGGCTGATCCGCGCCGGCTATCAGCTGCTCGACCTCATCACCTACTTCACCGTCGGCCCGAAGGAGGCCCGCG
CCTGGACCATCCATCGCGGCACCAAGGCGCCGGCGGCGGCGGGCGTCATTCACACCGATTTCGAGAAGGGCTTCATCCGC
GCCGAGACCATCGCCTATGCAGACTACGTCGCGCTCGGCGGCGAGGCGGGCGCGCGCGAGGGCGGCAAGCTCAGGCTCGA
GGGCAAGGAGTATGTCGTCGCCGACGGCGACGTGATGCACTTCCGCTTCAACAATTAG

Upstream 100 bases:

>100_bases
GTGCATCTGGCGCTGCAGGCCAAGGGTTTTCTGGACAAGGGCGACGCCGGCGCCGCGTGAGGCGCGCGCGACGTCGCCGT
GAGAGGATGCGAGACGGGTC

Downstream 100 bases:

>100_bases
CGGCGCCGGACTTTGAGGCGAGGGGCGGACTACATCCGCCCCTGCTCGCGGATCGCGCCGAGATGCTCGTTGATGCGGAA
GACGATCAGCACGAACTCGG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MGFKCGIVGLPNVGKSTLFNALTETAAAQAANYPFCTIEPNVGEVAVPDPRLEKLAAIAKSGQIIPTRLTFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIAHVVRCFEDSDITHVEGKIAPLADIETIETELMLADLDSLEKRVDNLAKKAKGGDKDAK
EQHDLVTRALVLLRDGKPARLLERKPEEERAFGMLGLLSSKPVLYVCNVEEGSAKDGNSFSQAVFARAKEEGAIAVVISA
KIESEIATLSREERVDFLETLGLEEAGLDRLIRAGYQLLDLITYFTVGPKEARAWTIHRGTKAPAAAGVIHTDFEKGFIR
AETIAYADYVALGGEAGAREGGKLRLEGKEYVVADGDVMHFRFNN

Sequences:

>Translated_365_residues
MGFKCGIVGLPNVGKSTLFNALTETAAAQAANYPFCTIEPNVGEVAVPDPRLEKLAAIAKSGQIIPTRLTFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIAHVVRCFEDSDITHVEGKIAPLADIETIETELMLADLDSLEKRVDNLAKKAKGGDKDAK
EQHDLVTRALVLLRDGKPARLLERKPEEERAFGMLGLLSSKPVLYVCNVEEGSAKDGNSFSQAVFARAKEEGAIAVVISA
KIESEIATLSREERVDFLETLGLEEAGLDRLIRAGYQLLDLITYFTVGPKEARAWTIHRGTKAPAAAGVIHTDFEKGFIR
AETIAYADYVALGGEAGAREGGKLRLEGKEYVVADGDVMHFRFNN
>Mature_364_residues
GFKCGIVGLPNVGKSTLFNALTETAAAQAANYPFCTIEPNVGEVAVPDPRLEKLAAIAKSGQIIPTRLTFVDIAGLVRGA
SKGEGLGNQFLANIREVDAIAHVVRCFEDSDITHVEGKIAPLADIETIETELMLADLDSLEKRVDNLAKKAKGGDKDAKE
QHDLVTRALVLLRDGKPARLLERKPEEERAFGMLGLLSSKPVLYVCNVEEGSAKDGNSFSQAVFARAKEEGAIAVVISAK
IESEIATLSREERVDFLETLGLEEAGLDRLIRAGYQLLDLITYFTVGPKEARAWTIHRGTKAPAAAGVIHTDFEKGFIRA
ETIAYADYVALGGEAGAREGGKLRLEGKEYVVADGDVMHFRFNN

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.2934782608696, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=38.0530973451327, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=58.2417582417582, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17509631, Length=367, Percent_Identity=41.6893732970027, Blast_Score=290, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=41.0810810810811, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=35.4497354497354, Blast_Score=223, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6321649, Length=161, Percent_Identity=40.3726708074534, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24640873, Length=371, Percent_Identity=43.9353099730458, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24640877, Length=371, Percent_Identity=43.9353099730458, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24640875, Length=371, Percent_Identity=43.9353099730458, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=41.7682926829268, Blast_Score=240, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24585318, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39409; Mature: 39278

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTETAAAQAANYPFCTIEPNVGEVAVPDPRLEKLAAIAK
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SGQIIPTRLTFVDIAGLVRGASKGEGLGNQFLANIREVDAIAHVVRCFEDSDITHVEGKI
CCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
APLADIETIETELMLADLDSLEKRVDNLAKKAKGGDKDAKEQHDLVTRALVLLRDGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
LLERKPEEERAFGMLGLLSSKPVLYVCNVEEGSAKDGNSFSQAVFARAKEEGAIAVVISA
HHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
KIESEIATLSREERVDFLETLGLEEAGLDRLIRAGYQLLDLITYFTVGPKEARAWTIHRG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
TKAPAAAGVIHTDFEKGFIRAETIAYADYVALGGEAGAREGGKLRLEGKEYVVADGDVMH
CCCCCCCCEEEECHHCCCEEHHHHHHHHHHEECCCCCCCCCCEEEECCCEEEEECCCEEE
FRFNN
EEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTETAAAQAANYPFCTIEPNVGEVAVPDPRLEKLAAIAK
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SGQIIPTRLTFVDIAGLVRGASKGEGLGNQFLANIREVDAIAHVVRCFEDSDITHVEGKI
CCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
APLADIETIETELMLADLDSLEKRVDNLAKKAKGGDKDAKEQHDLVTRALVLLRDGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
LLERKPEEERAFGMLGLLSSKPVLYVCNVEEGSAKDGNSFSQAVFARAKEEGAIAVVISA
HHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
KIESEIATLSREERVDFLETLGLEEAGLDRLIRAGYQLLDLITYFTVGPKEARAWTIHRG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
TKAPAAAGVIHTDFEKGFIRAETIAYADYVALGGEAGAREGGKLRLEGKEYVVADGDVMH
CCCCCCCCEEEECHHCCCEEHHHHHHHHHHEECCCCCCCCCCEEEECCCEEEEECCCEEE
FRFNN
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA