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The map label for this gene is mutT1 [H]

Identifier: 146342530

GI number: 146342530

Start: 5894168

End: 5895190

Strand: Reverse

Name: mutT1 [H]

Synonym: BRADO5692

Alternate gene names: 146342530

Gene position: 5895190-5894168 (Counterclockwise)

Preceding gene: 146342531

Following gene: 146342529

Centisome position: 79.06

GC content: 70.09

Gene sequence:

>1023_bases
ATGGCGAGAACGCCGATCATGGCAGCAGGCGGCATCGTGCTGCGGCGGGAGCAACCGCCGCGGATCGCGGTCGTGCGCCT
GCGCAAGCGCGACGAATGGGTGCTGCCCAAGGGCAAGCTCGATGATGGCGAGACGCCGCGCGACGCGGCCAAGCGCGAGG
TGCTCGAGGAGACCGGCCACAGGGTGACCGTGCACGAATTCCTCGGCACCCTCGTCCACGACACCGGCGCGCGCTCTAAG
GTCGTGCACTACTGGCGGATGGAAGCAAGCGGCACGCAGACGCAGCCGCTGATGGACGATGTACGCGCGGTCGACTGGCT
GCCGCTGGATGCCGCGGTCGAACGCCTCTCCCGGGATCATGAAAAGACGTTCCTGGAGACCGTGGGCCCCTATGCGCTCG
CCGGCCTGATCCGCAAGGCCAAGGCCAAGCCGGCGCTGGAGCCCAAAACTGTCGACAAGGCCGTGGATAAGGCTGTCGAC
AAAGCTGTGGTCGAGAAGATCGATAACGCGTCGGTCGAAAAGCTTGCCGCGGAGAAGCCTGCGACGGCGAAGCGGCGCCG
TAGCCGCGTGGCTGCGCAGCCGGTGCCCTCCGAATTGCCGGCCGCGCCGCCTGTGGCAGCTGAGCTGCTCGCGCCGATCC
CCGAAGCCGCGGAGCCGGCGGAGATCCTCCCGGAGGTGGCGAGCGAACCCGTGCGGGATGAGAGCCCCGCGTTGGATCTC
CCGGAGCCGGTTGCTTCGGAGGCGGCGCCGCCGAAAACGCAGCCGGTGGCCGCGCCCGAGGCTGCGATCCCGGAGCGCGT
GCCGGCGGATCTCGAGCGTGTCGAGGCTGTGGCGGCGGCGATCAAATCGCTCGTGCCTGCGCCATCCGAGCCTGTGAGCG
ACGACAGTCGACAGAGCAAGGATGCGCCGACGCCCGAGCCGGCGGCTGAGCTGCTGGACAGTGCCGGCGCCGACGCGCCG
GACGGCCATGGCCGCCGCAGCCTGGCGCAGAAAATGCGGGCCTGGCTCGGCCGGGCTGCCTGA

Upstream 100 bases:

>100_bases
GGGCGCACGACGGGTATCTCGATTTCCCGTTGCGCGTCGCCATATCCTGGCGTTGAACTGGCGAATCGCATGGGTTGCAA
CCCGTTATGTGGGAGAGGCG

Downstream 100 bases:

>100_bases
GCCCGCCGAACCTCGCGCCGGAGCGGAAGCGACCGCGCGGGCCTTGGCCATGCCCGTCGTCCGCCGCGCGAAAAATTGTT
GAGAACTATTCGCGCCATTG

Product: putative NUDIX hydrolase (modular protein)

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MARTPIMAAGGIVLRREQPPRIAVVRLRKRDEWVLPKGKLDDGETPRDAAKREVLEETGHRVTVHEFLGTLVHDTGARSK
VVHYWRMEASGTQTQPLMDDVRAVDWLPLDAAVERLSRDHEKTFLETVGPYALAGLIRKAKAKPALEPKTVDKAVDKAVD
KAVVEKIDNASVEKLAAEKPATAKRRRSRVAAQPVPSELPAAPPVAAELLAPIPEAAEPAEILPEVASEPVRDESPALDL
PEPVASEAAPPKTQPVAAPEAAIPERVPADLERVEAVAAAIKSLVPAPSEPVSDDSRQSKDAPTPEPAAELLDSAGADAP
DGHGRRSLAQKMRAWLGRAA

Sequences:

>Translated_340_residues
MARTPIMAAGGIVLRREQPPRIAVVRLRKRDEWVLPKGKLDDGETPRDAAKREVLEETGHRVTVHEFLGTLVHDTGARSK
VVHYWRMEASGTQTQPLMDDVRAVDWLPLDAAVERLSRDHEKTFLETVGPYALAGLIRKAKAKPALEPKTVDKAVDKAVD
KAVVEKIDNASVEKLAAEKPATAKRRRSRVAAQPVPSELPAAPPVAAELLAPIPEAAEPAEILPEVASEPVRDESPALDL
PEPVASEAAPPKTQPVAAPEAAIPERVPADLERVEAVAAAIKSLVPAPSEPVSDDSRQSKDAPTPEPAAELLDSAGADAP
DGHGRRSLAQKMRAWLGRAA
>Mature_339_residues
ARTPIMAAGGIVLRREQPPRIAVVRLRKRDEWVLPKGKLDDGETPRDAAKREVLEETGHRVTVHEFLGTLVHDTGARSKV
VHYWRMEASGTQTQPLMDDVRAVDWLPLDAAVERLSRDHEKTFLETVGPYALAGLIRKAKAKPALEPKTVDKAVDKAVDK
AVVEKIDNASVEKLAAEKPATAKRRRSRVAAQPVPSELPAAPPVAAELLAPIPEAAEPAEILPEVASEPVRDESPALDLP
EPVASEAAPPKTQPVAAPEAAIPERVPADLERVEAVAAAIKSLVPAPSEPVSDDSRQSKDAPTPEPAAELLDSAGADAPD
GHGRRSLAQKMRAWLGRAA

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX; PF00300 PGAM [H]

EC number: NA

Molecular weight: Translated: 36471; Mature: 36340

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTPIMAAGGIVLRREQPPRIAVVRLRKRDEWVLPKGKLDDGETPRDAAKREVLEETGH
CCCCCCEECCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
RVTVHEFLGTLVHDTGARSKVVHYWRMEASGTQTQPLMDDVRAVDWLPLDAAVERLSRDH
EEEHHHHHHHHHHCCCCHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
EKTFLETVGPYALAGLIRKAKAKPALEPKTVDKAVDKAVDKAVVEKIDNASVEKLAAEKP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
ATAKRRRSRVAAQPVPSELPAAPPVAAELLAPIPEAAEPAEILPEVASEPVRDESPALDL
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
PEPVASEAAPPKTQPVAAPEAAIPERVPADLERVEAVAAAIKSLVPAPSEPVSDDSRQSK
CCHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCC
DAPTPEPAAELLDSAGADAPDGHGRRSLAQKMRAWLGRAA
CCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARTPIMAAGGIVLRREQPPRIAVVRLRKRDEWVLPKGKLDDGETPRDAAKREVLEETGH
CCCCCEECCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
RVTVHEFLGTLVHDTGARSKVVHYWRMEASGTQTQPLMDDVRAVDWLPLDAAVERLSRDH
EEEHHHHHHHHHHCCCCHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
EKTFLETVGPYALAGLIRKAKAKPALEPKTVDKAVDKAVDKAVVEKIDNASVEKLAAEKP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
ATAKRRRSRVAAQPVPSELPAAPPVAAELLAPIPEAAEPAEILPEVASEPVRDESPALDL
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
PEPVASEAAPPKTQPVAAPEAAIPERVPADLERVEAVAAAIKSLVPAPSEPVSDDSRQSK
CCHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCC
DAPTPEPAAELLDSAGADAPDGHGRRSLAQKMRAWLGRAA
CCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]