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The map label for this gene is caiD [C]

Identifier: 146342140

GI number: 146342140

Start: 5500514

End: 5501293

Strand: Reverse

Name: caiD [C]

Synonym: BRADO5287

Alternate gene names: 146342140

Gene position: 5501293-5500514 (Counterclockwise)

Preceding gene: 146342141

Following gene: 146342138

Centisome position: 73.78

GC content: 65.26

Gene sequence:

>780_bases
ATGACCAACGACAGCGTGATTCTCGACAGGCGCGGGCAGGCCCTCTGGATCACCATCAACCGGCCCGAGAAGCGCAACGC
GCTCAATGGCGACGTCATCGCCGGGATCTCGCGCGGCTATCGTCAGGCGCATGACGATCCCGAGGTGCGCGTCATCGTGC
TGACCGGAGCGGGTGACAAGGCGTTCTGCGCCGGCGCCGACCTGCAGAACTCGGGGGCCGCCTTCGCGATGGATTTCTCG
CGGCCCAATGTCGACTATGCCGATCTGCTCAGGCTGTCGCAGAACGCCACCAAGCCGGCGATCGCCCGCGTGGGCGGCGT
CTGCATGGCGGGCGGCATGGGCCTGTTGTGCATGACCGATATGGCGGTCGCGGCCGACCACGTCGTCTTCGGCCTGCCGG
AGGTGAAGGTCGGCGTGTTCCCGATGCAGGTGCTGAGCCTGCTGCAGAGCATCGCGCCGCCACGCCTCGTCAACGAATGG
GCTTTGACGGGGGAGCCGTTTGATGCCAAGGCGGCGCAGGCCGCCGGCCTGCTGAACCACGTCGTTCCCGCCGCCGAGCT
CGATGCCAAGATCGACTGGCTGATCGGCCGTTTGGTTGACAAATCGCCGACAGCGATCCGCCGCGGCAAATACGCGATGC
GCGCGATCGCCTCGATGTCGTTCGACGAGTCCATTGCCTATCTCGAAAGCCAGATCGCATTGCTGGCGATGACCGAGGAT
GCCAAGGAAGGGCTGAAGGCTTTCGCAGAAAAGCGTAAGCCGGTCTGGCCGGGGAAGTAG

Upstream 100 bases:

>100_bases
CGAGATCGGCCGCCGCGCGGCCTCCTGACGCAAGTTTTCCTTGCCGTCCGCGGCTATCCCGCGACAATCCCGCACTCGAC
ATCCATCGACAGGCGAAGCC

Downstream 100 bases:

>100_bases
TCGCGCGCCTGACGGCCGCTCTGTTGTCCTCGCTGTCATGCTCTGCGAAGGCGGAGCATCCAGTACGCCGAGACCTCTCG
GTTCGATCATAACCGCCTCT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTNDSVILDRRGQALWITINRPEKRNALNGDVIAGISRGYRQAHDDPEVRVIVLTGAGDKAFCAGADLQNSGAAFAMDFS
RPNVDYADLLRLSQNATKPAIARVGGVCMAGGMGLLCMTDMAVAADHVVFGLPEVKVGVFPMQVLSLLQSIAPPRLVNEW
ALTGEPFDAKAAQAAGLLNHVVPAAELDAKIDWLIGRLVDKSPTAIRRGKYAMRAIASMSFDESIAYLESQIALLAMTED
AKEGLKAFAEKRKPVWPGK

Sequences:

>Translated_259_residues
MTNDSVILDRRGQALWITINRPEKRNALNGDVIAGISRGYRQAHDDPEVRVIVLTGAGDKAFCAGADLQNSGAAFAMDFS
RPNVDYADLLRLSQNATKPAIARVGGVCMAGGMGLLCMTDMAVAADHVVFGLPEVKVGVFPMQVLSLLQSIAPPRLVNEW
ALTGEPFDAKAAQAAGLLNHVVPAAELDAKIDWLIGRLVDKSPTAIRRGKYAMRAIASMSFDESIAYLESQIALLAMTED
AKEGLKAFAEKRKPVWPGK
>Mature_258_residues
TNDSVILDRRGQALWITINRPEKRNALNGDVIAGISRGYRQAHDDPEVRVIVLTGAGDKAFCAGADLQNSGAAFAMDFSR
PNVDYADLLRLSQNATKPAIARVGGVCMAGGMGLLCMTDMAVAADHVVFGLPEVKVGVFPMQVLSLLQSIAPPRLVNEWA
LTGEPFDAKAAQAAGLLNHVVPAAELDAKIDWLIGRLVDKSPTAIRRGKYAMRAIASMSFDESIAYLESQIALLAMTEDA
KEGLKAFAEKRKPVWPGK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=256, Percent_Identity=31.25, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI31542718, Length=244, Percent_Identity=29.9180327868852, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI37594469, Length=191, Percent_Identity=30.8900523560209, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI37594471, Length=191, Percent_Identity=30.8900523560209, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI70995211, Length=262, Percent_Identity=29.7709923664122, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=28.6852589641434, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=37.4045801526718, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787659, Length=262, Percent_Identity=32.4427480916031, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788597, Length=244, Percent_Identity=33.1967213114754, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082183, Length=251, Percent_Identity=29.8804780876494, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787660, Length=249, Percent_Identity=28.5140562248996, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=260, Percent_Identity=31.9230769230769, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=29.7959183673469, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17549921, Length=220, Percent_Identity=27.7272727272727, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=256, Percent_Identity=26.5625, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25144160, Length=212, Percent_Identity=29.7169811320755, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25144157, Length=212, Percent_Identity=29.7169811320755, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=205, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=272, Percent_Identity=23.8970588235294, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=267, Percent_Identity=27.7153558052434, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=227, Percent_Identity=26.8722466960352, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=213, Percent_Identity=30.0469483568075, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129971, Length=239, Percent_Identity=31.3807531380753, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24653477, Length=239, Percent_Identity=31.3807531380753, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24653139, Length=250, Percent_Identity=29.6, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=27.0992366412214, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920382, Length=260, Percent_Identity=24.6153846153846, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571730, Length=142, Percent_Identity=30.9859154929577, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571729, Length=141, Percent_Identity=30.4964539007092, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654903, Length=209, Percent_Identity=26.7942583732057, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27817; Mature: 27686

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDSVILDRRGQALWITINRPEKRNALNGDVIAGISRGYRQAHDDPEVRVIVLTGAGDK
CCCCCEEEECCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
AFCAGADLQNSGAAFAMDFSRPNVDYADLLRLSQNATKPAIARVGGVCMAGGMGLLCMTD
EEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHCCHHHHCCCCHHHHHH
MAVAADHVVFGLPEVKVGVFPMQVLSLLQSIAPPRLVNEWALTGEPFDAKAAQAAGLLNH
HHHHHHHHEECCCCCEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
VVPAAELDAKIDWLIGRLVDKSPTAIRRGKYAMRAIASMSFDESIAYLESQIALLAMTED
HCCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEECHH
AKEGLKAFAEKRKPVWPGK
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TNDSVILDRRGQALWITINRPEKRNALNGDVIAGISRGYRQAHDDPEVRVIVLTGAGDK
CCCCEEEECCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
AFCAGADLQNSGAAFAMDFSRPNVDYADLLRLSQNATKPAIARVGGVCMAGGMGLLCMTD
EEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHCCHHHHCCCCHHHHHH
MAVAADHVVFGLPEVKVGVFPMQVLSLLQSIAPPRLVNEWALTGEPFDAKAAQAAGLLNH
HHHHHHHHEECCCCCEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
VVPAAELDAKIDWLIGRLVDKSPTAIRRGKYAMRAIASMSFDESIAYLESQIALLAMTED
HCCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEECHH
AKEGLKAFAEKRKPVWPGK
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA