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The map label for this gene is yxnA [H]

Identifier: 146342136

GI number: 146342136

Start: 5496176

End: 5497180

Strand: Direct

Name: yxnA [H]

Synonym: BRADO5283

Alternate gene names: 146342136

Gene position: 5496176-5497180 (Clockwise)

Preceding gene: 146342135

Following gene: 146342137

Centisome position: 73.71

GC content: 70.45

Gene sequence:

>1005_bases
ATGCCTCGCAGACCAGCCCGCACCATCATCATCACCGGCGCCTCCGCCGGCGTCGGCCGCGCCATGGCGAAACGCTTCGC
GGAGGCCGGCGACCGCGTCGGCGTGATCGCCCGCGACGAGGAGGCGTTGCGCGACGTTCAGCGCGAGCTGCAGGCGCGCT
TTGCCCATGCCGAATACGAGGCGGTCGATGTCGCCGACGCGCAGGCGCTGTTCGCGGCCGCCGAACGGCTCGAGCAGCGG
CTGGGTCCGGTCGATATCTGGATCAACGACGCGATGGAAACGGTGTTCTCGACCGTCGCCGACATCACGGCCGACGAATT
CCGCCGTGTCACCGAGGTCACCTATCTCGGCTTCGTGCACGGCACGATGGCGGCGCTACGCTCCATGCGCCGCCGCGGCG
AAGGCCGCATCATCCAGATCGGCTCGGCGCTCGCCTATCGCGGCATTCCCCTGCAGGCCGCCTATTGCGGCGCCAAGCAC
GCGATCCGCGGCTTCACCGACTCGCTGCGCGCCGAGCTGATGCATGAGCGCTCGCGCATCACGCTGTGCATGGTCGATCT
GCCGGCCGTGAACACGCCGCAATTCGACTGGGCGCGCGCCCATCTCGCGCACACGCCGCGGCCGATGGGACGGCCGGTCG
AGCCGGAGGTGATTGCCGATGCGGTCTATCGCGTCGCCGACGGCGGCTTCCGCGAATATTGGATCGGCTGGCCGACGCTG
CTCACGATCATCGGCAACGCCGTCGCGCCGGCCGTGCTCGACCGCTATCTCGCCGCCAAGGCGATCGCGGGCCAGCAGAC
CGACGTGCCGCTGGTCCCAGACCGCAGCGACAATCTCGACCGCCCAGTGACGCGCCTGCACCGCACGCGCGGCTCATTCA
GCCAAGGCGCGGCGCAACAGTCGGTGCTGCTGCCGGGCGACGTTGCGCGCGCCGCCACCGTCGCGATCGGCGCGGCGATC
TTCTTTGCGCTGGGAGCGACGATGGGCCGGCGGCGCTGGCGCTAG

Upstream 100 bases:

>100_bases
CTGCGGGATCTTACCAAGCTTTCATCGGCGCGGCTCTTCGCGCCCGAAACATTGCCGCGGGCTGCACGTTTGTACGACGG
GGCGCGTGGAGAACCCGGAC

Downstream 100 bases:

>100_bases
CCGCACGCCGGCTCTTGCGTGACACCGGCAAGGTGCGCTTCTCTGGTCCGCGGCGTCCCTTCGGGTCCGGAGCGTCTCCA
TGACCATCGAGAGCATCAGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPRRPARTIIITGASAGVGRAMAKRFAEAGDRVGVIARDEEALRDVQRELQARFAHAEYEAVDVADAQALFAAAERLEQR
LGPVDIWINDAMETVFSTVADITADEFRRVTEVTYLGFVHGTMAALRSMRRRGEGRIIQIGSALAYRGIPLQAAYCGAKH
AIRGFTDSLRAELMHERSRITLCMVDLPAVNTPQFDWARAHLAHTPRPMGRPVEPEVIADAVYRVADGGFREYWIGWPTL
LTIIGNAVAPAVLDRYLAAKAIAGQQTDVPLVPDRSDNLDRPVTRLHRTRGSFSQGAAQQSVLLPGDVARAATVAIGAAI
FFALGATMGRRRWR

Sequences:

>Translated_334_residues
MPRRPARTIIITGASAGVGRAMAKRFAEAGDRVGVIARDEEALRDVQRELQARFAHAEYEAVDVADAQALFAAAERLEQR
LGPVDIWINDAMETVFSTVADITADEFRRVTEVTYLGFVHGTMAALRSMRRRGEGRIIQIGSALAYRGIPLQAAYCGAKH
AIRGFTDSLRAELMHERSRITLCMVDLPAVNTPQFDWARAHLAHTPRPMGRPVEPEVIADAVYRVADGGFREYWIGWPTL
LTIIGNAVAPAVLDRYLAAKAIAGQQTDVPLVPDRSDNLDRPVTRLHRTRGSFSQGAAQQSVLLPGDVARAATVAIGAAI
FFALGATMGRRRWR
>Mature_333_residues
PRRPARTIIITGASAGVGRAMAKRFAEAGDRVGVIARDEEALRDVQRELQARFAHAEYEAVDVADAQALFAAAERLEQRL
GPVDIWINDAMETVFSTVADITADEFRRVTEVTYLGFVHGTMAALRSMRRRGEGRIIQIGSALAYRGIPLQAAYCGAKHA
IRGFTDSLRAELMHERSRITLCMVDLPAVNTPQFDWARAHLAHTPRPMGRPVEPEVIADAVYRVADGGFREYWIGWPTLL
TIIGNAVAPAVLDRYLAAKAIAGQQTDVPLVPDRSDNLDRPVTRLHRTRGSFSQGAAQQSVLLPGDVARAATVAIGAAIF
FALGATMGRRRWR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=218, Percent_Identity=36.2385321100917, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI7706318, Length=180, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=28.0612244897959, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=33.6842105263158, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=33.6842105263158, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7705925, Length=221, Percent_Identity=25.7918552036199, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI142976729, Length=239, Percent_Identity=24.6861924686192, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI157739938, Length=240, Percent_Identity=24.5833333333333, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI223718074, Length=176, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI210032110, Length=165, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI22507405, Length=183, Percent_Identity=26.2295081967213, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI7657478, Length=181, Percent_Identity=27.0718232044199, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40254992, Length=216, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI31543615, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788459, Length=190, Percent_Identity=32.6315789473684, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787335, Length=164, Percent_Identity=29.8780487804878, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082100, Length=219, Percent_Identity=26.4840182648402, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787820, Length=174, Percent_Identity=25.8620689655172, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787905, Length=221, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=167, Percent_Identity=29.3413173652695, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=221, Percent_Identity=25.7918552036199, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=218, Percent_Identity=26.1467889908257, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=26.1306532663317, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=179, Percent_Identity=22.9050279329609, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358495, Length=181, Percent_Identity=35.3591160220994, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356301, Length=267, Percent_Identity=26.9662921348315, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=28.8557213930348, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI116007236, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007238, Length=196, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=25.4437869822485, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364494, Length=236, Percent_Identity=29.2372881355932, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=26.5060240963855, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648693, Length=233, Percent_Identity=28.755364806867, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355889, Length=233, Percent_Identity=28.755364806867, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640492, Length=167, Percent_Identity=25.1497005988024, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=265, Percent_Identity=24.1509433962264, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571387, Length=197, Percent_Identity=27.9187817258883, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641388, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36622; Mature: 36491

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRRPARTIIITGASAGVGRAMAKRFAEAGDRVGVIARDEEALRDVQRELQARFAHAEYE
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
AVDVADAQALFAAAERLEQRLGPVDIWINDAMETVFSTVADITADEFRRVTEVTYLGFVH
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTMAALRSMRRRGEGRIIQIGSALAYRGIPLQAAYCGAKHAIRGFTDSLRAELMHERSRI
HHHHHHHHHHHCCCCCEEEECCHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCE
TLCMVDLPAVNTPQFDWARAHLAHTPRPMGRPVEPEVIADAVYRVADGGFREYWIGWPTL
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LTIIGNAVAPAVLDRYLAAKAIAGQQTDVPLVPDRSDNLDRPVTRLHRTRGSFSQGAAQQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCC
SVLLPGDVARAATVAIGAAIFFALGATMGRRRWR
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PRRPARTIIITGASAGVGRAMAKRFAEAGDRVGVIARDEEALRDVQRELQARFAHAEYE
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
AVDVADAQALFAAAERLEQRLGPVDIWINDAMETVFSTVADITADEFRRVTEVTYLGFVH
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTMAALRSMRRRGEGRIIQIGSALAYRGIPLQAAYCGAKHAIRGFTDSLRAELMHERSRI
HHHHHHHHHHHCCCCCEEEECCHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCE
TLCMVDLPAVNTPQFDWARAHLAHTPRPMGRPVEPEVIADAVYRVADGGFREYWIGWPTL
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LTIIGNAVAPAVLDRYLAAKAIAGQQTDVPLVPDRSDNLDRPVTRLHRTRGSFSQGAAQQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCC
SVLLPGDVARAATVAIGAAIFFALGATMGRRRWR
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]