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The map label for this gene is crt [H]

Identifier: 146342129

GI number: 146342129

Start: 5487180

End: 5487977

Strand: Reverse

Name: crt [H]

Synonym: BRADO5276

Alternate gene names: 146342129

Gene position: 5487977-5487180 (Counterclockwise)

Preceding gene: 146342130

Following gene: 146342128

Centisome position: 73.6

GC content: 67.67

Gene sequence:

>798_bases
ATGAGCGCTCCTGCGACCGGATCCGACGATCTCCTCTATGCCGTCGACGACGGCATCGCCAAGATCACCTTCAACCGGCC
GCAGGCGCGCAACGCGATGACCTTCGCGATGTACGACCAGATGGCCTCGATCTGCGAGGCCATCAACGCCGACCGGTCGA
TCAAGGCGCTGATCCTGACCGGGGCCGGCGACAAGGCCTTCGCCTCCGGCACCGACATCTCGCAGTTCCGCGCCTTCAAG
ACCGCGCAGGACGCGCTCGACTACGAGGCGCGGATCGATCGCGTGCTCGGCACGCTCGAGCTTTGCCGCGTGCCGGTGAT
CGCCGCGATCGCGGGCGCCTGCACCGGCGGCGGCGCCGGCATCGCCGCGTGCTGCGATATCCGCATCGGCACCGAGACCA
CGCGCATGGGCTTTCCGATCGCGCGCACGCTCGGCAACTGCCTGTCGATGTCGAACATCTCCCGCGTGGTATCGCTGATC
GGGCCGGCGCGCACCAAGGACCTGATCTTCAAGGCCCGCCTGGTCGAGGCGCCGGAGGCGCTCGCGCTCGGCCTGCTCAA
CGAGATCGTGCCCGACGTCGAGACCTTGCAGACGCGCGCCCTGGAGACCGCGAAGCTGGTCGCCTCGCATGCGCCGATCA
CGCTCGAAGTCACCAAGGAGGCGGTGCGCCGCATCCGCCGCACCTTGTCCCGCGATGAGGGCGAGGACCTCATCCTGCGC
GCGTATATGAGCGAGGATTTCCGCGAGGGCATGGACGCGTTCCTCAACAAGCGGACACCGAACTGGAAGGGCAAGTAG

Upstream 100 bases:

>100_bases
GCCTCGCGCTCGCCAATGTCCCGCATCGCGCCGGTGGCGTGCTCGCGGCGATGGATGTCCTCAAGGCGCGCGAGGCTGCG
CCGATTCCGAAGGTGGCCTG

Downstream 100 bases:

>100_bases
TCCGATGATGATGCGACCTTATGCCGAGGACATGAGGCTGCATCTCGCTTGTGTTCTTGAAGTGACCACAATAAGCCAGC
AGTATCCTGGTAGGGTAAAA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSAPATGSDDLLYAVDDGIAKITFNRPQARNAMTFAMYDQMASICEAINADRSIKALILTGAGDKAFASGTDISQFRAFK
TAQDALDYEARIDRVLGTLELCRVPVIAAIAGACTGGGAGIAACCDIRIGTETTRMGFPIARTLGNCLSMSNISRVVSLI
GPARTKDLIFKARLVEAPEALALGLLNEIVPDVETLQTRALETAKLVASHAPITLEVTKEAVRRIRRTLSRDEGEDLILR
AYMSEDFREGMDAFLNKRTPNWKGK

Sequences:

>Translated_265_residues
MSAPATGSDDLLYAVDDGIAKITFNRPQARNAMTFAMYDQMASICEAINADRSIKALILTGAGDKAFASGTDISQFRAFK
TAQDALDYEARIDRVLGTLELCRVPVIAAIAGACTGGGAGIAACCDIRIGTETTRMGFPIARTLGNCLSMSNISRVVSLI
GPARTKDLIFKARLVEAPEALALGLLNEIVPDVETLQTRALETAKLVASHAPITLEVTKEAVRRIRRTLSRDEGEDLILR
AYMSEDFREGMDAFLNKRTPNWKGK
>Mature_264_residues
SAPATGSDDLLYAVDDGIAKITFNRPQARNAMTFAMYDQMASICEAINADRSIKALILTGAGDKAFASGTDISQFRAFKT
AQDALDYEARIDRVLGTLELCRVPVIAAIAGACTGGGAGIAACCDIRIGTETTRMGFPIARTLGNCLSMSNISRVVSLIG
PARTKDLIFKARLVEAPEALALGLLNEIVPDVETLQTRALETAKLVASHAPITLEVTKEAVRRIRRTLSRDEGEDLILRA
YMSEDFREGMDAFLNKRTPNWKGK

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=251, Percent_Identity=29.8804780876494, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI70995211, Length=213, Percent_Identity=30.0469483568075, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI31542718, Length=266, Percent_Identity=27.0676691729323, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI260274832, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI45643119, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI260275230, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI20127408, Length=216, Percent_Identity=27.3148148148148, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI213417737, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI157694516, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787659, Length=262, Percent_Identity=29.3893129770992, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1788597, Length=272, Percent_Identity=30.5147058823529, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=30.46875, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=29.520295202952, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=30.8270676691729, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790281, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=28.2868525896414, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=223, Percent_Identity=29.1479820627803, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=29.7619047619048, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=207, Percent_Identity=27.536231884058, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=264, Percent_Identity=26.1363636363636, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=162, Percent_Identity=29.0123456790123, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=259, Percent_Identity=26.2548262548263, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=206, Percent_Identity=27.1844660194175, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24653139, Length=268, Percent_Identity=29.4776119402985, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=28.5140562248996, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=28.5140562248996, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920382, Length=257, Percent_Identity=28.0155642023346, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357171, Length=190, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24650670, Length=181, Percent_Identity=28.7292817679558, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550169, Length=253, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19922422, Length=265, Percent_Identity=21.8867924528302, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28603; Mature: 28472

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPATGSDDLLYAVDDGIAKITFNRPQARNAMTFAMYDQMASICEAINADRSIKALILT
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GAGDKAFASGTDISQFRAFKTAQDALDYEARIDRVLGTLELCRVPVIAAIAGACTGGGAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IAACCDIRIGTETTRMGFPIARTLGNCLSMSNISRVVSLIGPARTKDLIFKARLVEAPEA
EEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LALGLLNEIVPDVETLQTRALETAKLVASHAPITLEVTKEAVRRIRRTLSRDEGEDLILR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHH
AYMSEDFREGMDAFLNKRTPNWKGK
HHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAPATGSDDLLYAVDDGIAKITFNRPQARNAMTFAMYDQMASICEAINADRSIKALILT
CCCCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GAGDKAFASGTDISQFRAFKTAQDALDYEARIDRVLGTLELCRVPVIAAIAGACTGGGAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IAACCDIRIGTETTRMGFPIARTLGNCLSMSNISRVVSLIGPARTKDLIFKARLVEAPEA
EEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LALGLLNEIVPDVETLQTRALETAKLVASHAPITLEVTKEAVRRIRRTLSRDEGEDLILR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHH
AYMSEDFREGMDAFLNKRTPNWKGK
HHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]