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The map label for this gene is ycgM [C]

Identifier: 146341982

GI number: 146341982

Start: 5316106

End: 5316957

Strand: Direct

Name: ycgM [C]

Synonym: BRADO5118

Alternate gene names: 146341982

Gene position: 5316106-5316957 (Clockwise)

Preceding gene: 146341981

Following gene: 146341995

Centisome position: 71.29

GC content: 65.85

Gene sequence:

>852_bases
ATGAAATTCACGAGCTTCACGATCAACAACGTCAGGTCCTGGGGACTGGTCGAAGGCGATGAGGTCGCCGATCTCGGCGC
GCTTTTGCGCGACCGCTTCCCGGACCTGAAGTCGGCGATCGCCGCCGGCGCCTTGAAGGACGTCGCTGTGGCGGCGTCCG
GCGCCAAGCGGCATCCGCTCTCGGCCATCACCTTTCTTCCGGTGATCCCGAACCCCGACAAGATCCTCTGCATCGGCCTG
AACTACGAGACCCACCGCAAGGAGACCGGCCGCTCGGAGGTCGAGAACCCCACCGTGTTCGGCCGCTTCGCCAACAGCCA
GACCGGGCACCTCTCCAACATCATCCGCCCGCGCGTCTCGACCGATCTCGACTTCGAGGGCGAGCTCGCCATCGTCATCG
GCAAGCCCGGCCGCTACATTCCGCGAGCCGAGGCGTTCCAGCACATCGCGGGCTATGCCTGCTACAACGAGGGCAGCGTG
CGCGACTTCCAGCGCCACACGCATCAGTTCACCCCGGGCAAGAACTTCCCCGACACCGGCGCGTTCGGCCCGTGGCTCGT
CACATCAGACGAGATCGATGATCTCGGCCCGCTGAAGCTGCAGACGCGGCTCAACGGCGAGGTCGTCCAGGAGGCGACGA
TCAGCCAGATGATCTTCGACATCCCGCGCCAGATCGAATACTGCTCCTCCTTCACCCGTCTGGAGCCCGGCGACGTCATC
GCCACCGGCACTCCCGGCGGCGTCGGCTCCCGCCGCACGCCCCCGCTGTGGATGAAACCGGGCGACGTCGTGGAAGTGGA
GATCGACAAGATCGGGCTGCTGCGCAATGGGATCGCGGACGAGGCGGAGTGA

Upstream 100 bases:

>100_bases
TCTTCCCGGAGCGCACCATCGCGCGCTTTGCAAGAACGGCGCAGGAACCCGCTTCCCCCTCCGCCGTACCGGCGGTCTCG
ACCTGACAAAAGGACGTCCC

Downstream 100 bases:

>100_bases
TCGCCCCTTCGTAGAGCTTGTGAGCCAATTTGAGTTCAGGGCTGAGTTTGCGACGAGGGGGCTGTCGCCGCGGGGATAGC
CGTTGTGTGCGGCTCTGTGC

Product: putative bifunctional enzyme with isomerase/decarboxylase activity

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKFTSFTINNVRSWGLVEGDEVADLGALLRDRFPDLKSAIAAGALKDVAVAASGAKRHPLSAITFLPVIPNPDKILCIGL
NYETHRKETGRSEVENPTVFGRFANSQTGHLSNIIRPRVSTDLDFEGELAIVIGKPGRYIPRAEAFQHIAGYACYNEGSV
RDFQRHTHQFTPGKNFPDTGAFGPWLVTSDEIDDLGPLKLQTRLNGEVVQEATISQMIFDIPRQIEYCSSFTRLEPGDVI
ATGTPGGVGSRRTPPLWMKPGDVVEVEIDKIGLLRNGIADEAE

Sequences:

>Translated_283_residues
MKFTSFTINNVRSWGLVEGDEVADLGALLRDRFPDLKSAIAAGALKDVAVAASGAKRHPLSAITFLPVIPNPDKILCIGL
NYETHRKETGRSEVENPTVFGRFANSQTGHLSNIIRPRVSTDLDFEGELAIVIGKPGRYIPRAEAFQHIAGYACYNEGSV
RDFQRHTHQFTPGKNFPDTGAFGPWLVTSDEIDDLGPLKLQTRLNGEVVQEATISQMIFDIPRQIEYCSSFTRLEPGDVI
ATGTPGGVGSRRTPPLWMKPGDVVEVEIDKIGLLRNGIADEAE
>Mature_283_residues
MKFTSFTINNVRSWGLVEGDEVADLGALLRDRFPDLKSAIAAGALKDVAVAASGAKRHPLSAITFLPVIPNPDKILCIGL
NYETHRKETGRSEVENPTVFGRFANSQTGHLSNIIRPRVSTDLDFEGELAIVIGKPGRYIPRAEAFQHIAGYACYNEGSV
RDFQRHTHQFTPGKNFPDTGAFGPWLVTSDEIDDLGPLKLQTRLNGEVVQEATISQMIFDIPRQIEYCSSFTRLEPGDVI
ATGTPGGVGSRRTPPLWMKPGDVVEVEIDKIGLLRNGIADEAE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=223, Percent_Identity=41.2556053811659, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI40786394, Length=223, Percent_Identity=40.8071748878924, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI215422413, Length=179, Percent_Identity=35.7541899441341, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI13654274, Length=179, Percent_Identity=35.7541899441341, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI66348062, Length=179, Percent_Identity=35.7541899441341, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1787428, Length=200, Percent_Identity=29, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=33.6734693877551, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6324161, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28572127, Length=249, Percent_Identity=37.7510040160643, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24663695, Length=220, Percent_Identity=33.1818181818182, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28571789, Length=213, Percent_Identity=30.0469483568075, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 30986; Mature: 30986

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00047 HISTONE_H4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTSFTINNVRSWGLVEGDEVADLGALLRDRFPDLKSAIAAGALKDVAVAASGAKRHPL
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
SAITFLPVIPNPDKILCIGLNYETHRKETGRSEVENPTVFGRFANSQTGHLSNIIRPRVS
EEEEEEECCCCCCEEEEEECCCHHHHHHCCHHHCCCCEEEEEECCCCCCHHHHHHCCCCC
TDLDFEGELAIVIGKPGRYIPRAEAFQHIAGYACYNEGSVRDFQRHTHQFTPGKNFPDTG
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCCCCCCCCC
AFGPWLVTSDEIDDLGPLKLQTRLNGEVVQEATISQMIFDIPRQIEYCSSFTRLEPGDVI
CCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
ATGTPGGVGSRRTPPLWMKPGDVVEVEIDKIGLLRNGIADEAE
EECCCCCCCCCCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKFTSFTINNVRSWGLVEGDEVADLGALLRDRFPDLKSAIAAGALKDVAVAASGAKRHPL
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
SAITFLPVIPNPDKILCIGLNYETHRKETGRSEVENPTVFGRFANSQTGHLSNIIRPRVS
EEEEEEECCCCCCEEEEEECCCHHHHHHCCHHHCCCCEEEEEECCCCCCHHHHHHCCCCC
TDLDFEGELAIVIGKPGRYIPRAEAFQHIAGYACYNEGSVRDFQRHTHQFTPGKNFPDTG
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCCCCCCCCC
AFGPWLVTSDEIDDLGPLKLQTRLNGEVVQEATISQMIFDIPRQIEYCSSFTRLEPGDVI
CCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
ATGTPGGVGSRRTPPLWMKPGDVVEVEIDKIGLLRNGIADEAE
EECCCCCCCCCCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]