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The map label for this gene is oxlT [H]

Identifier: 146341834

GI number: 146341834

Start: 5154125

End: 5155411

Strand: Direct

Name: oxlT [H]

Synonym: BRADO4963

Alternate gene names: 146341834

Gene position: 5154125-5155411 (Clockwise)

Preceding gene: 146341833

Following gene: 146341835

Centisome position: 69.12

GC content: 63.25

Gene sequence:

>1287_bases
ATGACGGACCTGGCTCACGCGGGGGCCCCCGCATCGGCAAGAGTAAGCGACGCCTATCGCTGGACACAGCTCGTCGTCGG
CGTCGCGGCGATGGTCATGATCGCCAACTACCAGTATGGCTGGACCTTCTTCGTCCCCGACATCTCCAAGACCTTCGGCT
GGGACCGCGCCTCGATCCAGTGGGCCTTCTTCTTGTTCGTCTTGTTCGAGACCTGGCTGGTGCCGGTCGAGGGCTGGTTC
GTCGACAAATACGGCCCGCGCATCGTCGTCCTGGTAGGCGGCGTGCTCTGCGCGATCGGCTGGATGATCAACGCCTACGC
CACCTCGCTCAACGGCTACTATGTCGGCATGATCATCGCGGGCATCGGCGCCGGCGGCGTCTATGGCACCTGCGTCGGCA
ATGCGCTGAAGTGGTTCCCCGACAAGCGCGGCCTCGCGGCGGGTATCACCGCCGCAGGCTTCGGGGCCGGCTCGGCGGCC
ACCGTCGTTCCGATCCAGGCCATGATCCGCGACTCCGGCTTCCAGACCACTTTCCTGTATTTCGGCCTGGGACAGGGCAT
CATCATCGTCATCCTCGCCTTCTTCCTGTTCGCTCCCAAAGATGGCCAGGTGCCCGCGGTCACGCAGAATTCCAACCTCG
TGCAGAGCCGCCGCAACTACAACCCGACCGAAGTGATCCGGCAGCCGATCTTCTGGCTGATGTACTTCATGTTCGTGATC
GTCGGCGCCGGCGGCCTGATGGTGACCGCCAATCTCAAGCCGATCGCCGGCGACTGGAAAGTCGACAACATCCCGGTGAC
GCTGATCGGCATGACGATGACGGCGGTGACCTTCGCGGCGACCATCGACCGCATCCTCAACGGCCTGACGCGTCCGTTCT
TCGGCTGGATCTCGGACATGATCGGCCGCGAGAACACGATGTTCATCGCCTTCGGCATGGAAGGCATCGGGATCTGGGCG
CTGTACATGCTCGGCCATGATCCGGTGTGGTTCGTGATCCTCTCCGGCTTCGTGTTCTTCGCCTGGGGTGAGATCTATTC
GCTGTTCCCCTCGACCTGCACCGACACCTTCGGCACCAAGTTCGCGACCACCAATGCCGGCCTGCTCTACACCGCCAAGG
GCACGGCCGCGCTGCTGGTGCCGATCGCCAACTACATGCAGCAGTCGTCGGGCAATTGGGACCAGGTGTTCATGATCGCG
GCCGGCGCCAACATCCTGGCCTCGATCCTGGCGATCGCGGTGCTCAAGCCTTGGCGTAAAGTCGTGGTGGAGAAGTCGAC
GCTCTGA

Upstream 100 bases:

>100_bases
AGTGGCGCGATGCGCGAGGAGCGGCTTGAGCGCTGGCATCAAGCATACAAGGATGTGCCGAGCGCCAGAAATAATACGAG
AAGCGCGATTGGGAGGATAA

Downstream 100 bases:

>100_bases
CGACCGCCCTTCGCATCGCAGCGAAAAATAAAAATAAGCCGATTTGACACAAGCAACGCTCGGCATTTTGCCGAGCGTTT
TCTTTTGCTTGCTGGCTCAA

Product: putative oxalate/formate antiporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTDLAHAGAPASARVSDAYRWTQLVVGVAAMVMIANYQYGWTFFVPDISKTFGWDRASIQWAFFLFVLFETWLVPVEGWF
VDKYGPRIVVLVGGVLCAIGWMINAYATSLNGYYVGMIIAGIGAGGVYGTCVGNALKWFPDKRGLAAGITAAGFGAGSAA
TVVPIQAMIRDSGFQTTFLYFGLGQGIIIVILAFFLFAPKDGQVPAVTQNSNLVQSRRNYNPTEVIRQPIFWLMYFMFVI
VGAGGLMVTANLKPIAGDWKVDNIPVTLIGMTMTAVTFAATIDRILNGLTRPFFGWISDMIGRENTMFIAFGMEGIGIWA
LYMLGHDPVWFVILSGFVFFAWGEIYSLFPSTCTDTFGTKFATTNAGLLYTAKGTAALLVPIANYMQQSSGNWDQVFMIA
AGANILASILAIAVLKPWRKVVVEKSTL

Sequences:

>Translated_428_residues
MTDLAHAGAPASARVSDAYRWTQLVVGVAAMVMIANYQYGWTFFVPDISKTFGWDRASIQWAFFLFVLFETWLVPVEGWF
VDKYGPRIVVLVGGVLCAIGWMINAYATSLNGYYVGMIIAGIGAGGVYGTCVGNALKWFPDKRGLAAGITAAGFGAGSAA
TVVPIQAMIRDSGFQTTFLYFGLGQGIIIVILAFFLFAPKDGQVPAVTQNSNLVQSRRNYNPTEVIRQPIFWLMYFMFVI
VGAGGLMVTANLKPIAGDWKVDNIPVTLIGMTMTAVTFAATIDRILNGLTRPFFGWISDMIGRENTMFIAFGMEGIGIWA
LYMLGHDPVWFVILSGFVFFAWGEIYSLFPSTCTDTFGTKFATTNAGLLYTAKGTAALLVPIANYMQQSSGNWDQVFMIA
AGANILASILAIAVLKPWRKVVVEKSTL
>Mature_427_residues
TDLAHAGAPASARVSDAYRWTQLVVGVAAMVMIANYQYGWTFFVPDISKTFGWDRASIQWAFFLFVLFETWLVPVEGWFV
DKYGPRIVVLVGGVLCAIGWMINAYATSLNGYYVGMIIAGIGAGGVYGTCVGNALKWFPDKRGLAAGITAAGFGAGSAAT
VVPIQAMIRDSGFQTTFLYFGLGQGIIIVILAFFLFAPKDGQVPAVTQNSNLVQSRRNYNPTEVIRQPIFWLMYFMFVIV
GAGGLMVTANLKPIAGDWKVDNIPVTLIGMTMTAVTFAATIDRILNGLTRPFFGWISDMIGRENTMFIAFGMEGIGIWAL
YMLGHDPVWFVILSGFVFFAWGEIYSLFPSTCTDTFGTKFATTNAGLLYTAKGTAALLVPIANYMQQSSGNWDQVFMIAA
GANILASILAIAVLKPWRKVVVEKSTL

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Homo sapiens, GI291621700, Length=407, Percent_Identity=21.1302211302211, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1789969, Length=360, Percent_Identity=23.3333333333333, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46605; Mature: 46474

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLAHAGAPASARVSDAYRWTQLVVGVAAMVMIANYQYGWTFFVPDISKTFGWDRASIQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCHHHH
WAFFLFVLFETWLVPVEGWFVDKYGPRIVVLVGGVLCAIGWMINAYATSLNGYYVGMIIA
HHHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEHEE
GIGAGGVYGTCVGNALKWFPDKRGLAAGITAAGFGAGSAATVVPIQAMIRDSGFQTTFLY
ECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
FGLGQGIIIVILAFFLFAPKDGQVPAVTQNSNLVQSRRNYNPTEVIRQPIFWLMYFMFVI
EECCCHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VGAGGLMVTANLKPIAGDWKVDNIPVTLIGMTMTAVTFAATIDRILNGLTRPFFGWISDM
HCCCCEEEEECCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRENTMFIAFGMEGIGIWALYMLGHDPVWFVILSGFVFFAWGEIYSLFPSTCTDTFGTK
HCCCCEEEEEECCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCE
FATTNAGLLYTAKGTAALLVPIANYMQQSSGNWDQVFMIAAGANILASILAIAVLKPWRK
EEECCCCEEEEECCCEEHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
VVVEKSTL
HHHCCCCC
>Mature Secondary Structure 
TDLAHAGAPASARVSDAYRWTQLVVGVAAMVMIANYQYGWTFFVPDISKTFGWDRASIQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCHHHH
WAFFLFVLFETWLVPVEGWFVDKYGPRIVVLVGGVLCAIGWMINAYATSLNGYYVGMIIA
HHHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEHEE
GIGAGGVYGTCVGNALKWFPDKRGLAAGITAAGFGAGSAATVVPIQAMIRDSGFQTTFLY
ECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
FGLGQGIIIVILAFFLFAPKDGQVPAVTQNSNLVQSRRNYNPTEVIRQPIFWLMYFMFVI
EECCCHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VGAGGLMVTANLKPIAGDWKVDNIPVTLIGMTMTAVTFAATIDRILNGLTRPFFGWISDM
HCCCCEEEEECCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRENTMFIAFGMEGIGIWALYMLGHDPVWFVILSGFVFFAWGEIYSLFPSTCTDTFGTK
HCCCCEEEEEECCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCE
FATTNAGLLYTAKGTAALLVPIANYMQQSSGNWDQVFMIAAGANILASILAIAVLKPWRK
EEECCCCEEEEECCCEEHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
VVVEKSTL
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]