Click here to switch to the map view.

The map label for this gene is cobM [H]

Identifier: 146341780

GI number: 146341780

Start: 5099410

End: 5100171

Strand: Reverse

Name: cobM [H]

Synonym: BRADO4899

Alternate gene names: 146341780

Gene position: 5100171-5099410 (Counterclockwise)

Preceding gene: 146341781

Following gene: 146341778

Centisome position: 68.4

GC content: 68.5

Gene sequence:

>762_bases
ATGACCGTGCACTTCATCGGCGCCGGTCCGGGCGCGGCCGATCTGATCACCGTGCGCGGCCGCGATCTCATCGCGCGATG
TCCGGTGTGTCTCTATGCGGGCTCGCTGGTTCCGACGGCGCTGCTCGACCATTGTCCAAGAGGCGCACGCATCGTCGACA
CCGCGCCGATGGCGCTCGACGAGATCATCGCCGAAATGGCGCGGGCCACCGCTGCCGGTGAGGACGTGGCGCGACTGCAT
TCGGGCGACCTCTCGATCTGGAGCGCGCTCGGCGAGCAACTGCGCCGCCTCGACGCGCTGAAGATCCCCTACACGGTGAC
CCCGGGGGTGCCGTCCTTTTCCGCCGCCGCGGCCGCGCTTGGCCGTGAGTTGACCTTGCCGGGGCTCGCGCAGTCCGTCG
TGCTGACGCGGACGTCCGGGCGGGCCTCGGCGATGCCCGAGACGGAGCAGCTCTCGCTGTTCGCGCAATCGCGCGCAACG
CTCGCCATCCATCTCTCGATCCATGTGCTCGATCAGGTCGTCGCGGAGCTCCGACCGCATTATGGCGAGGACTGCCCGGT
CGCGATCGTGTATCGCGCGAGCTGGCCGGATCAGCAGATCATCACGGCGACGCTCGCGACGATCGTCGATCGCGCCGCCG
CGGCCAGGCTGGAGCGGACCGCGCTGATCCTGGTCGGCCGTGCGCTCAGCGGCAGAAATTTTTGCAACAGCGCGCTGTAT
GATGCCGATTATCAGCGGCGCTTCCGCGGGAGGGGCGAATGA

Upstream 100 bases:

>100_bases
CAGCGGCCGGCCGCAATGCGCGGCTGATCATGCCGCGGCTCGCCAACGCCTCGGCGACCTGCGCACTGGCGCAAGGCGAG
GGACCTGCGGAGACCGGCCG

Downstream 100 bases:

>100_bases
TTAGCTCCGTGGCTTTGGCCGACCAGTCTGCCACCGCGGTCGAACACCGCGATATCGAGCGCGATGTCGTTGTCGCCGAG
CGCGCGGCGCGCGGTCTGCC

Product: precorrin-4 C(11)-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSLVPTALLDHCPRGARIVDTAPMALDEIIAEMARATAAGEDVARLH
SGDLSIWSALGEQLRRLDALKIPYTVTPGVPSFSAAAAALGRELTLPGLAQSVVLTRTSGRASAMPETEQLSLFAQSRAT
LAIHLSIHVLDQVVAELRPHYGEDCPVAIVYRASWPDQQIITATLATIVDRAAAARLERTALILVGRALSGRNFCNSALY
DADYQRRFRGRGE

Sequences:

>Translated_253_residues
MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSLVPTALLDHCPRGARIVDTAPMALDEIIAEMARATAAGEDVARLH
SGDLSIWSALGEQLRRLDALKIPYTVTPGVPSFSAAAAALGRELTLPGLAQSVVLTRTSGRASAMPETEQLSLFAQSRAT
LAIHLSIHVLDQVVAELRPHYGEDCPVAIVYRASWPDQQIITATLATIVDRAAAARLERTALILVGRALSGRNFCNSALY
DADYQRRFRGRGE
>Mature_252_residues
TVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSLVPTALLDHCPRGARIVDTAPMALDEIIAEMARATAAGEDVARLHS
GDLSIWSALGEQLRRLDALKIPYTVTPGVPSFSAAAAALGRELTLPGLAQSVVLTRTSGRASAMPETEQLSLFAQSRATL
AIHLSIHVLDQVVAELRPHYGEDCPVAIVYRASWPDQQIITATLATIVDRAAAARLERTALILVGRALSGRNFCNSALYD
ADYQRRFRGRGE

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=241, Percent_Identity=29.4605809128631, Blast_Score=77, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322922, Length=254, Percent_Identity=26.7716535433071, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 27035; Mature: 26904

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSLVPTALLDHCPRGARIVDTAPMALD
CEEEEEECCCCCCCEEEECCCHHHHHCCHHHHHCHHHHHHHHHHCCCCCEEECCCHHHHH
EIIAEMARATAAGEDVARLHSGDLSIWSALGEQLRRLDALKIPYTVTPGVPSFSAAAAAL
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHH
GRELTLPGLAQSVVLTRTSGRASAMPETEQLSLFAQSRATLAIHLSIHVLDQVVAELRPH
CCCCCCCCHHHHEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCC
YGEDCPVAIVYRASWPDQQIITATLATIVDRAAAARLERTALILVGRALSGRNFCNSALY
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHC
DADYQRRFRGRGE
CCHHHHHHCCCCC
>Mature Secondary Structure 
TVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSLVPTALLDHCPRGARIVDTAPMALD
EEEEEECCCCCCCEEEECCCHHHHHCCHHHHHCHHHHHHHHHHCCCCCEEECCCHHHHH
EIIAEMARATAAGEDVARLHSGDLSIWSALGEQLRRLDALKIPYTVTPGVPSFSAAAAAL
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHH
GRELTLPGLAQSVVLTRTSGRASAMPETEQLSLFAQSRATLAIHLSIHVLDQVVAELRPH
CCCCCCCCHHHHEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCC
YGEDCPVAIVYRASWPDQQIITATLATIVDRAAAARLERTALILVGRALSGRNFCNSALY
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHC
DADYQRRFRGRGE
CCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]