Click here to switch to the map view.

The map label for this gene is dinB [H]

Identifier: 146341432

GI number: 146341432

Start: 4723141

End: 4724439

Strand: Direct

Name: dinB [H]

Synonym: BRADO4523

Alternate gene names: 146341432

Gene position: 4723141-4724439 (Clockwise)

Preceding gene: 146341431

Following gene: 146341434

Centisome position: 63.34

GC content: 68.28

Gene sequence:

>1299_bases
ATGGCGCCAGAAGGAGGGACGCACGCGGTCAGCCGGCCGACCTGCTTCTGTCGCGACTGCCTGTCGGATCTCGCCTCCAC
GGCGCGCCGCTGCAGCGCCTGCGGCTCGCCGCGGCTGGTCCGCCATCGCTCCCTGCCCGGGCTCACCTTGGCCCATATCG
ACTGCGACGCGTTCTATGCCACGGTCGAGAAGCGCGACAATCCAGAGGTCGCCGACCGTCCGGTCATCATCGGCGGCGGC
AAGCGCGGCGTGGTCTCGGCGGCCTGCTACATCGCCCGCACCTATGGCGTGCGCTCGGCGATGCCGATGTTCAAGGCCCT
GGAGCTGTGCCCCTCCGCGGTGGTGATACGGCCGGACATGGCGAAATACGTCCGGGTCGGCCGCGAGGTCCGGCAGGCGA
TGCAGGCGCTGACGCCGCTGGTCGAACCGCTGTCGATCGACGAGGCATTCCTCGACCTCTCCGGCACCGAGCGTGTCCAC
GGCATGATCCCGGCGAAAGTGTTGGCGCGCTTCGCCCGCGAGGTGGAGCAGATCATCGGCATCACGGTCTCTGTCGGGCT
GTCCTGCAACAAGTTCCTTGCCAAAATCGCCTCCGATCTCGACAAGCCCCGCGGCTTCGCCGCGCTCGACCAGGACGAGG
CCCGCGATATGCTTGCCGACAAGCCGGTGGGCTTCATCTTCGGCGTCGGACCGGCCAGCCAGCAGCGGCTGGCGCAACAC
GGCTTTCGCCTCATCTCCGACCTGCAGCGCGCCGACGAGATCGAGCTGATGAAGCAGTTCGGCGGTGAGGGCCGAAGGCT
TTGGCGGCTGGCGCGCGGCCTCGACGATCGCAAGGTGGTGGCCGACCGCGGCGCCAAGACGATCTCCAGCGAGACCACCT
TCGACACCGACATCCGCGACTACGCGACCTTGGAGAAGCTGCTCTGGCGGCTGTCGGAGAAGGTCTCGGCGCGGCTGAAG
GCGAGCCAGCTCGCCGGCTCGACCATCACGCTGAAGCTGAAGACATCAGATTTCCGCCAGCGCACCCGCTCGCAGTCGAT
CGCCGCGCCCACCCAGCTCGCCGGCAAGATCTTCGCCATCTGCAAGGAGATGCTGGCACGAGAGACCGATGGCACGGCGT
TCCGCCTGATGGGCGCCGGCGTCAGCGCGCTGCGCCCGGGCTCGGAAGCCTCCGACACCGACATGCTCGACCGACGCTCA
GCCTCCGCCGAGCGCGCGATGGATGCGCTACGCAAGAAATTCGGCCAGGCCGCGGTGATCCGCGGCATCGCCTATGGCGG
GCCGGAGGAGACGGAATGA

Upstream 100 bases:

>100_bases
AGGCTTTTGCCGAAAGCTCCAAGTTACATCCGACCAATATCATGGCCGCAAGGCAGGTATTGGGCGACCGGCAGTGGGAG
CGCGACGTGCCGTGAGCACG

Downstream 100 bases:

>100_bases
CGCCCGTCTCAGTTGCTGCAGGGCTTGTTGGAGTCCTTGCTGTCCTTGACGTCGAACTTGCCAAGCGCGCCTGCAATGAC
GAAGTCATTGTAGTCGAGCA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MAPEGGTHAVSRPTCFCRDCLSDLASTARRCSACGSPRLVRHRSLPGLTLAHIDCDAFYATVEKRDNPEVADRPVIIGGG
KRGVVSAACYIARTYGVRSAMPMFKALELCPSAVVIRPDMAKYVRVGREVRQAMQALTPLVEPLSIDEAFLDLSGTERVH
GMIPAKVLARFAREVEQIIGITVSVGLSCNKFLAKIASDLDKPRGFAALDQDEARDMLADKPVGFIFGVGPASQQRLAQH
GFRLISDLQRADEIELMKQFGGEGRRLWRLARGLDDRKVVADRGAKTISSETTFDTDIRDYATLEKLLWRLSEKVSARLK
ASQLAGSTITLKLKTSDFRQRTRSQSIAAPTQLAGKIFAICKEMLARETDGTAFRLMGAGVSALRPGSEASDTDMLDRRS
ASAERAMDALRKKFGQAAVIRGIAYGGPEETE

Sequences:

>Translated_432_residues
MAPEGGTHAVSRPTCFCRDCLSDLASTARRCSACGSPRLVRHRSLPGLTLAHIDCDAFYATVEKRDNPEVADRPVIIGGG
KRGVVSAACYIARTYGVRSAMPMFKALELCPSAVVIRPDMAKYVRVGREVRQAMQALTPLVEPLSIDEAFLDLSGTERVH
GMIPAKVLARFAREVEQIIGITVSVGLSCNKFLAKIASDLDKPRGFAALDQDEARDMLADKPVGFIFGVGPASQQRLAQH
GFRLISDLQRADEIELMKQFGGEGRRLWRLARGLDDRKVVADRGAKTISSETTFDTDIRDYATLEKLLWRLSEKVSARLK
ASQLAGSTITLKLKTSDFRQRTRSQSIAAPTQLAGKIFAICKEMLARETDGTAFRLMGAGVSALRPGSEASDTDMLDRRS
ASAERAMDALRKKFGQAAVIRGIAYGGPEETE
>Mature_431_residues
APEGGTHAVSRPTCFCRDCLSDLASTARRCSACGSPRLVRHRSLPGLTLAHIDCDAFYATVEKRDNPEVADRPVIIGGGK
RGVVSAACYIARTYGVRSAMPMFKALELCPSAVVIRPDMAKYVRVGREVRQAMQALTPLVEPLSIDEAFLDLSGTERVHG
MIPAKVLARFAREVEQIIGITVSVGLSCNKFLAKIASDLDKPRGFAALDQDEARDMLADKPVGFIFGVGPASQQRLAQHG
FRLISDLQRADEIELMKQFGGEGRRLWRLARGLDDRKVVADRGAKTISSETTFDTDIRDYATLEKLLWRLSEKVSARLKA
SQLAGSTITLKLKTSDFRQRTRSQSIAAPTQLAGKIFAICKEMLARETDGTAFRLMGAGVSALRPGSEASDTDMLDRRSA
SAERAMDALRKKFGQAAVIRGIAYGGPEETE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=269, Percent_Identity=28.996282527881, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI7706681, Length=269, Percent_Identity=28.996282527881, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI7705344, Length=116, Percent_Identity=42.2413793103448, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI154350220, Length=308, Percent_Identity=25.3246753246753, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1786425, Length=345, Percent_Identity=35.9420289855072, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1787432, Length=305, Percent_Identity=27.2131147540984, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=29.9492385786802, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI193205702, Length=346, Percent_Identity=28.3236994219653, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=346, Percent_Identity=24.5664739884393, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19923006, Length=367, Percent_Identity=25.0681198910082, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24668444, Length=352, Percent_Identity=25.5681818181818, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355641, Length=310, Percent_Identity=27.4193548387097, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644984, Length=310, Percent_Identity=27.4193548387097, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 47096; Mature: 46965

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEGGTHAVSRPTCFCRDCLSDLASTARRCSACGSPRLVRHRSLPGLTLAHIDCDAFYA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECHHHHHH
TVEKRDNPEVADRPVIIGGGKRGVVSAACYIARTYGVRSAMPMFKALELCPSAVVIRPDM
HHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCH
AKYVRVGREVRQAMQALTPLVEPLSIDEAFLDLSGTERVHGMIPAKVLARFAREVEQIIG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHC
ITVSVGLSCNKFLAKIASDLDKPRGFAALDQDEARDMLADKPVGFIFGVGPASQQRLAQH
CHHEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
GFRLISDLQRADEIELMKQFGGEGRRLWRLARGLDDRKVVADRGAKTISSETTFDTDIRD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCHHCCCCCCCCCCHHH
YATLEKLLWRLSEKVSARLKASQLAGSTITLKLKTSDFRQRTRSQSIAAPTQLAGKIFAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHH
CKEMLARETDGTAFRLMGAGVSALRPGSEASDTDMLDRRSASAERAMDALRKKFGQAAVI
HHHHHHCCCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RGIAYGGPEETE
HHHHCCCCCCCC
>Mature Secondary Structure 
APEGGTHAVSRPTCFCRDCLSDLASTARRCSACGSPRLVRHRSLPGLTLAHIDCDAFYA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECHHHHHH
TVEKRDNPEVADRPVIIGGGKRGVVSAACYIARTYGVRSAMPMFKALELCPSAVVIRPDM
HHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCH
AKYVRVGREVRQAMQALTPLVEPLSIDEAFLDLSGTERVHGMIPAKVLARFAREVEQIIG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHC
ITVSVGLSCNKFLAKIASDLDKPRGFAALDQDEARDMLADKPVGFIFGVGPASQQRLAQH
CHHEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
GFRLISDLQRADEIELMKQFGGEGRRLWRLARGLDDRKVVADRGAKTISSETTFDTDIRD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCHHCCCCCCCCCCHHH
YATLEKLLWRLSEKVSARLKASQLAGSTITLKLKTSDFRQRTRSQSIAAPTQLAGKIFAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHH
CKEMLARETDGTAFRLMGAGVSALRPGSEASDTDMLDRRSASAERAMDALRKKFGQAAVI
HHHHHHCCCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RGIAYGGPEETE
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]