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The map label for this gene is acoR [H]

Identifier: 146341277

GI number: 146341277

Start: 4545051

End: 4546952

Strand: Direct

Name: acoR [H]

Synonym: BRADO4355

Alternate gene names: 146341277

Gene position: 4545051-4546952 (Clockwise)

Preceding gene: 146341266

Following gene: 146341278

Centisome position: 60.95

GC content: 67.46

Gene sequence:

>1902_bases
ATGACGATGCTGCCAGGCAGCCGACGCCTCGATGGCGCATGGTTGAAGCTGGACGATCAGGATCAGCCGCCAGGCGGTCA
GATGTCGGCCGACATCTACGACAGCTGGATGCGCTGCATCACGATGGGTCTCGATGCGCTGCGCCCACCCTCGCCTGAAT
TCGTCGATGCCGCCGTGCTGCGGCAGGAGCAGCAGCGCTGCTCGCTGGTGCGCGGCCTCGCTCTGGCGGAGATGCACACG
CTGCATCAGCAGATCGCCGGCTCGAACTTCATGATCGCGTTTGCAACCGCCGAAGGGCTGCTGCTCGACATCATCTCCGA
CTCGAGCTTCAGCGACGCCTCGGATGCCGCCTGTATCCGCGCCGGCTCGCTCTGGACCGAAAGCATCTGCGGCACCAACG
GGCTCGGAACGGCGGCCTTTCTCAAGCGGCCGATCGTCGTGCATGGACGCGAGCACTTCTTCGCCCGCTACAACAATCTG
ACCTGCGTGGCGGCGCCGATCTTTGGGCCCGACGGCGAGGTCGCCGGCATCCTCGACGCATCGTCCGACTGCATGTCGCG
GCAGGCGCACACCCAGGCGCTGGTCGCGATGGCCGCCACTCAGATCGAGAACGGGCTGTTCCGCGAGCAGCATCGCGGCG
ACATCCTGATCGCCTTTCACAACCGCGGCGAATATCTGCATACGTTGAGTGCCGGCCTGCTCGCCGTCGACAATGACGGC
CGCATTCTCGCCGCCAACCGCGCCGCGCGCGTGCTGCTGCATGGACTGCCCGCCTTCGCCGGCCGCCCGTTCGGCGATGT
CTTCCGGGGCCGGTTCAGCGACTTCGTCGACGAGGGCCGGCGCATGGAGCGGCAGCGGCTCGAGGACGACGTCGGCAGCC
AGTTCGTTGCCACGATCGAGAACAGCCGCCAGTTTCCGATGACGCATCGGGTGGTGTCGCCGCGACCGACACCGCTGAAG
AGCCCCGCGGCGCCGTTCGTCTCGGCCGATCAGCGGATCGCGGCCATCGTGCAGCGGGTCGCTGTCGCTGCCACACGCAA
GATGCCGATCCTCATCCGTGGCGAGACCGGCACCGGCAAGGAGCAGATGGCGCGACACGCGCATGCCGCGAGCCGGCGCA
GTGGCGCGTTCGTCGCGGTCAATTGCGCGGCCCTCCCCGACAGCCTGGTCGAGGCCGAGCTGTTCGGCTATACAGAGGGC
GCGTTCACCGGCGCCCGCAAGGGCGGCTCGGCCGGCCTGTTCAAGGAAGCCGATGGCGGCACGCTGTTCCTCGACGAGAT
CGGCGACATGCCGGTGACCCTGCAGGCGGTGCTGCTGCGCTTCCTCGACGACTGGACCGTTCGGCCGGTCGGCGGCAGCA
CGCGTGAAGTCGATGTGCTCCTGGTCTCGGCCACCAACGCCAATCTCGACGACGCCATCGCGAAGGGCCGGTTCAGATCC
GATCTGCTGTTTCGCCTCAACACGCTCGAGGTCACGCTGCTGCCGCTGCGCGAACGCAACGACTTCGCCGACATCGCGCG
CCATCTGATGCACAAGATCGATCCGTCGATCGCGCTGTCCGAAGCTGCGATTCAACGGCTGGCGCAACGGAGCTGGGACG
GCAACATCCGCGAGCTCCGCAACGCGCTGGCCCGGCTCTCGCTCAGCGAGACCGGCCTAGTGATCGACGCCGCCACCGTC
GATGCCGTCATCGGGGCCGATCGCCCTGAGGGAATGGCGGCGAAGATCACCGTGGACAGAGCTGCCGTGGAGGACGGCGC
TCCAGCCGACCTGCACGAGATCCAGCGCGCGCTCGTGCTCAGCACCTATGCCGACACCGGCAACAACATCAGCAAGACCG
CGCGGCGGCTCGGCATCTCGCGCAACACCGTCTATCGCGCGCTGCGCGGCAAGCCGGAGTAA

Upstream 100 bases:

>100_bases
GATTTCTGCTTTTCGCACGATTGCTCTATGCTGATCGACGCAGCGCCACGAACAAACAGCCGGGCGTGCCGGCGCTCCGG
CGGAACCGCGGACCGGGAGG

Downstream 100 bases:

>100_bases
CACGCGCCGCATCAATTTGGATCAATGTGAAAGGAGGCCACGATGTTCGAACCGGAGAACAGTCTCGAAGCGCTGATGCA
GGCGGCCGGCCGCGATCCCG

Product: sigma-54-dependent transcriptional regulator HTH Fis-type family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTMLPGSRRLDGAWLKLDDQDQPPGGQMSADIYDSWMRCITMGLDALRPPSPEFVDAAVLRQEQQRCSLVRGLALAEMHT
LHQQIAGSNFMIAFATAEGLLLDIISDSSFSDASDAACIRAGSLWTESICGTNGLGTAAFLKRPIVVHGREHFFARYNNL
TCVAAPIFGPDGEVAGILDASSDCMSRQAHTQALVAMAATQIENGLFREQHRGDILIAFHNRGEYLHTLSAGLLAVDNDG
RILAANRAARVLLHGLPAFAGRPFGDVFRGRFSDFVDEGRRMERQRLEDDVGSQFVATIENSRQFPMTHRVVSPRPTPLK
SPAAPFVSADQRIAAIVQRVAVAATRKMPILIRGETGTGKEQMARHAHAASRRSGAFVAVNCAALPDSLVEAELFGYTEG
AFTGARKGGSAGLFKEADGGTLFLDEIGDMPVTLQAVLLRFLDDWTVRPVGGSTREVDVLLVSATNANLDDAIAKGRFRS
DLLFRLNTLEVTLLPLRERNDFADIARHLMHKIDPSIALSEAAIQRLAQRSWDGNIRELRNALARLSLSETGLVIDAATV
DAVIGADRPEGMAAKITVDRAAVEDGAPADLHEIQRALVLSTYADTGNNISKTARRLGISRNTVYRALRGKPE

Sequences:

>Translated_633_residues
MTMLPGSRRLDGAWLKLDDQDQPPGGQMSADIYDSWMRCITMGLDALRPPSPEFVDAAVLRQEQQRCSLVRGLALAEMHT
LHQQIAGSNFMIAFATAEGLLLDIISDSSFSDASDAACIRAGSLWTESICGTNGLGTAAFLKRPIVVHGREHFFARYNNL
TCVAAPIFGPDGEVAGILDASSDCMSRQAHTQALVAMAATQIENGLFREQHRGDILIAFHNRGEYLHTLSAGLLAVDNDG
RILAANRAARVLLHGLPAFAGRPFGDVFRGRFSDFVDEGRRMERQRLEDDVGSQFVATIENSRQFPMTHRVVSPRPTPLK
SPAAPFVSADQRIAAIVQRVAVAATRKMPILIRGETGTGKEQMARHAHAASRRSGAFVAVNCAALPDSLVEAELFGYTEG
AFTGARKGGSAGLFKEADGGTLFLDEIGDMPVTLQAVLLRFLDDWTVRPVGGSTREVDVLLVSATNANLDDAIAKGRFRS
DLLFRLNTLEVTLLPLRERNDFADIARHLMHKIDPSIALSEAAIQRLAQRSWDGNIRELRNALARLSLSETGLVIDAATV
DAVIGADRPEGMAAKITVDRAAVEDGAPADLHEIQRALVLSTYADTGNNISKTARRLGISRNTVYRALRGKPE
>Mature_632_residues
TMLPGSRRLDGAWLKLDDQDQPPGGQMSADIYDSWMRCITMGLDALRPPSPEFVDAAVLRQEQQRCSLVRGLALAEMHTL
HQQIAGSNFMIAFATAEGLLLDIISDSSFSDASDAACIRAGSLWTESICGTNGLGTAAFLKRPIVVHGREHFFARYNNLT
CVAAPIFGPDGEVAGILDASSDCMSRQAHTQALVAMAATQIENGLFREQHRGDILIAFHNRGEYLHTLSAGLLAVDNDGR
ILAANRAARVLLHGLPAFAGRPFGDVFRGRFSDFVDEGRRMERQRLEDDVGSQFVATIENSRQFPMTHRVVSPRPTPLKS
PAAPFVSADQRIAAIVQRVAVAATRKMPILIRGETGTGKEQMARHAHAASRRSGAFVAVNCAALPDSLVEAELFGYTEGA
FTGARKGGSAGLFKEADGGTLFLDEIGDMPVTLQAVLLRFLDDWTVRPVGGSTREVDVLLVSATNANLDDAIAKGRFRSD
LLFRLNTLEVTLLPLRERNDFADIARHLMHKIDPSIALSEAAIQRLAQRSWDGNIRELRNALARLSLSETGLVIDAATVD
AVIGADRPEGMAAKITVDRAAVEDGAPADLHEIQRALVLSTYADTGNNISKTARRLGISRNTVYRALRGKPE

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=424, Percent_Identity=32.311320754717, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1788550, Length=302, Percent_Identity=38.0794701986755, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786524, Length=237, Percent_Identity=45.5696202531646, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1788905, Length=305, Percent_Identity=39.0163934426229, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1790299, Length=346, Percent_Identity=36.1271676300578, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790437, Length=301, Percent_Identity=38.2059800664452, Blast_Score=173, Evalue=4e-44,
Organism=Escherichia coli, GI87082117, Length=235, Percent_Identity=42.9787234042553, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789087, Length=311, Percent_Identity=36.0128617363344, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=37.8640776699029, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787583, Length=336, Percent_Identity=34.8214285714286, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87082152, Length=245, Percent_Identity=40, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1789828, Length=248, Percent_Identity=37.5, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081858, Length=539, Percent_Identity=23.5621521335807, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68638; Mature: 68507

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLPGSRRLDGAWLKLDDQDQPPGGQMSADIYDSWMRCITMGLDALRPPSPEFVDAAVL
CCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RQEQQRCSLVRGLALAEMHTLHQQIAGSNFMIAFATAEGLLLDIISDSSFSDASDAACIR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHEE
AGSLWTESICGTNGLGTAAFLKRPIVVHGREHFFARYNNLTCVAAPIFGPDGEVAGILDA
CCCHHHHHHCCCCCCCHHHHHHCCEEEECCHHHHEEECCCEEEEEEEECCCCCEEEEECC
SSDCMSRQAHTQALVAMAATQIENGLFREQHRGDILIAFHNRGEYLHTLSAGLLAVDNDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEECCCC
RILAANRAARVLLHGLPAFAGRPFGDVFRGRFSDFVDEGRRMERQRLEDDVGSQFVATIE
CEEECCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHH
NSRQFPMTHRVVSPRPTPLKSPAAPFVSADQRIAAIVQRVAVAATRKMPILIRGETGTGK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCH
EQMARHAHAASRRSGAFVAVNCAALPDSLVEAELFGYTEGAFTGARKGGSAGLFKEADGG
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEIGDMPVTLQAVLLRFLDDWTVRPVGGSTREVDVLLVSATNANLDDAIAKGRFRS
EEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEEECCCCHHHHHHHCCHHH
DLLFRLNTLEVTLLPLRERNDFADIARHLMHKIDPSIALSEAAIQRLAQRSWDGNIRELR
HHHEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHH
NALARLSLSETGLVIDAATVDAVIGADRPEGMAAKITVDRAAVEDGAPADLHEIQRALVL
HHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHH
STYADTGNNISKTARRLGISRNTVYRALRGKPE
HHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TMLPGSRRLDGAWLKLDDQDQPPGGQMSADIYDSWMRCITMGLDALRPPSPEFVDAAVL
CCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RQEQQRCSLVRGLALAEMHTLHQQIAGSNFMIAFATAEGLLLDIISDSSFSDASDAACIR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHEE
AGSLWTESICGTNGLGTAAFLKRPIVVHGREHFFARYNNLTCVAAPIFGPDGEVAGILDA
CCCHHHHHHCCCCCCCHHHHHHCCEEEECCHHHHEEECCCEEEEEEEECCCCCEEEEECC
SSDCMSRQAHTQALVAMAATQIENGLFREQHRGDILIAFHNRGEYLHTLSAGLLAVDNDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEECCCC
RILAANRAARVLLHGLPAFAGRPFGDVFRGRFSDFVDEGRRMERQRLEDDVGSQFVATIE
CEEECCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHH
NSRQFPMTHRVVSPRPTPLKSPAAPFVSADQRIAAIVQRVAVAATRKMPILIRGETGTGK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCH
EQMARHAHAASRRSGAFVAVNCAALPDSLVEAELFGYTEGAFTGARKGGSAGLFKEADGG
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEIGDMPVTLQAVLLRFLDDWTVRPVGGSTREVDVLLVSATNANLDDAIAKGRFRS
EEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEEECCCCHHHHHHHCCHHH
DLLFRLNTLEVTLLPLRERNDFADIARHLMHKIDPSIALSEAAIQRLAQRSWDGNIRELR
HHHEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHH
NALARLSLSETGLVIDAATVDAVIGADRPEGMAAKITVDRAAVEDGAPADLHEIQRALVL
HHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHH
STYADTGNNISKTARRLGISRNTVYRALRGKPE
HHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]