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The map label for this gene is 146341161

Identifier: 146341161

GI number: 146341161

Start: 4435445

End: 4436623

Strand: Reverse

Name: 146341161

Synonym: BRADO4233

Alternate gene names: NA

Gene position: 4436623-4435445 (Counterclockwise)

Preceding gene: 146341162

Following gene: 146341157

Centisome position: 59.5

GC content: 65.99

Gene sequence:

>1179_bases
ATGACGTCATCCAAGTTCGACCTCGTCGTCTACGGCGCCACCGGCTTCACGGGCAAGCTCGTCGCCGAATATCTTGCTAC
GCAGTATCGCCACGACGGCTCGCTGCGCTGGGCGATGGCCGGCCGGAGCCTGGACAAGCTCGCCGCCGTGCGCGACGAGA
TCGGCGCGCCGGCCGACACGCCGCTGATCGCGGCCGATGCATCGAATCCTGCATCGTTGAAAGCCATGGTGGCGCAGACC
AGGCTGGTGCTCACCACCGTCGGTCCCTATCAGCTCTATGGCAACGAACTGGTCGCGCTCTGCGCCGAAACCGGCACAGA
CTACGTCGATCTCTGCGGCGAGCCGGTGTGGATGCGGCAGATGATCGACAAGCACCAGGCGACCGCCGAACAGAGCGGCG
CCCGCATCGTGTTCTCCTGCGGCTTCGATTCCGTGCCGTTCGAGCTCGGCGTCTACTTCGTTCAGCAGCAGGCGAAAAAG
GTCCTCGGCGCCCCGGCCGCCCGCGTGAAGGGCCGCGTCCGCGGCATGAGCGGCACGCTGTCGGGCGGCACGGCCGCGAG
CGCCAAGGCGACCTTCGATGCGGTGGCCCAGGATCTCAGCCTGGTGGCGATCCTGAAGGATTTCTTCGCGCTGACGCCGG
GCTTCAAGGGCCCCAAGCAGCCGGCCGGCAACAAGCCTGTTTATGAGGAGGATCTGCAATCCTGGGCGGCGCCTTTCATG
ATGGCGCTGATCAACACCCGCAACGTCCACCGCTCCAACATGCTGATGGGTTTCCCCTACGGCCAGGACTTCGTCTACGA
CGAGATGGTGCTGACAGGTGCGGGCGAGAAGGGCGAGGCCAACGCCAAGAAGGTGATGGCGGCGAATGCCGAGAAAACCG
GCCCGAACGCGCCGAAGCCGGGCGAGGGCCCCTCCAAGGAGGAGCGCGACAACGGCTACTACAACATCCTCTTTGTCGCG
ATCGGCCCCGACGGCCGCCAGGTCCGCGCCACCGTCAAGGGCGACCGCGATCCCGGCTACGGCTCCACCTCGAAGATGAT
CAGCGAATGCGCCATCGGCCTTTTGCGCGATGGCGCCAGTGTGAAGGGCGGCTTCTGGACCCCGGGCGCCGCGCTGCAGG
ACAGCCTGATCAAGCGTCTGGTCGACAATGCCGGCCTGACGTTCACGGTGGAGGATTAG

Upstream 100 bases:

>100_bases
GAAGCGAAGCAATCCAGAGTCCCGTCCCCCGCCCTGGATTGCTTCGCTTTGCCCGCAATGACGGGGCAACCGTTTTGCAG
CTGATCTCCAGGGAACAAGA

Downstream 100 bases:

>100_bases
GAGACCGCGTGCGAGCCGATCGATGCTGATCGGCTCGCCTCCGCCTGGTGTGCGCGGGTGGCGGCGATCATGCCCCACAT
CGTGCCGAGCATCAGGAAGA

Product: putative saccharopine dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTSSKFDLVVYGATGFTGKLVAEYLATQYRHDGSLRWAMAGRSLDKLAAVRDEIGAPADTPLIAADASNPASLKAMVAQT
RLVLTTVGPYQLYGNELVALCAETGTDYVDLCGEPVWMRQMIDKHQATAEQSGARIVFSCGFDSVPFELGVYFVQQQAKK
VLGAPAARVKGRVRGMSGTLSGGTAASAKATFDAVAQDLSLVAILKDFFALTPGFKGPKQPAGNKPVYEEDLQSWAAPFM
MALINTRNVHRSNMLMGFPYGQDFVYDEMVLTGAGEKGEANAKKVMAANAEKTGPNAPKPGEGPSKEERDNGYYNILFVA
IGPDGRQVRATVKGDRDPGYGSTSKMISECAIGLLRDGASVKGGFWTPGAALQDSLIKRLVDNAGLTFTVED

Sequences:

>Translated_392_residues
MTSSKFDLVVYGATGFTGKLVAEYLATQYRHDGSLRWAMAGRSLDKLAAVRDEIGAPADTPLIAADASNPASLKAMVAQT
RLVLTTVGPYQLYGNELVALCAETGTDYVDLCGEPVWMRQMIDKHQATAEQSGARIVFSCGFDSVPFELGVYFVQQQAKK
VLGAPAARVKGRVRGMSGTLSGGTAASAKATFDAVAQDLSLVAILKDFFALTPGFKGPKQPAGNKPVYEEDLQSWAAPFM
MALINTRNVHRSNMLMGFPYGQDFVYDEMVLTGAGEKGEANAKKVMAANAEKTGPNAPKPGEGPSKEERDNGYYNILFVA
IGPDGRQVRATVKGDRDPGYGSTSKMISECAIGLLRDGASVKGGFWTPGAALQDSLIKRLVDNAGLTFTVED
>Mature_391_residues
TSSKFDLVVYGATGFTGKLVAEYLATQYRHDGSLRWAMAGRSLDKLAAVRDEIGAPADTPLIAADASNPASLKAMVAQTR
LVLTTVGPYQLYGNELVALCAETGTDYVDLCGEPVWMRQMIDKHQATAEQSGARIVFSCGFDSVPFELGVYFVQQQAKKV
LGAPAARVKGRVRGMSGTLSGGTAASAKATFDAVAQDLSLVAILKDFFALTPGFKGPKQPAGNKPVYEEDLQSWAAPFMM
ALINTRNVHRSNMLMGFPYGQDFVYDEMVLTGAGEKGEANAKKVMAANAEKTGPNAPKPGEGPSKEERDNGYYNILFVAI
GPDGRQVRATVKGDRDPGYGSTSKMISECAIGLLRDGASVKGGFWTPGAALQDSLIKRLVDNAGLTFTVED

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=428, Percent_Identity=28.7383177570093, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17560066, Length=435, Percent_Identity=28.5057471264368, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32567112, Length=248, Percent_Identity=34.2741935483871, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71991033, Length=159, Percent_Identity=32.7044025157233, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646278, Length=437, Percent_Identity=27.9176201372998, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24644140, Length=169, Percent_Identity=38.4615384615385, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24644142, Length=169, Percent_Identity=38.4615384615385, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21356081, Length=169, Percent_Identity=38.4615384615385, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 41792; Mature: 41661

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSKFDLVVYGATGFTGKLVAEYLATQYRHDGSLRWAMAGRSLDKLAAVRDEIGAPADT
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCC
PLIAADASNPASLKAMVAQTRLVLTTVGPYQLYGNELVALCAETGTDYVDLCGEPVWMRQ
CEEEECCCCCHHHHHHHHHHEEEEEECCCHHHHCCHHHHHHHHCCCCHHHHCCCHHHHHH
MIDKHQATAEQSGARIVFSCGFDSVPFELGVYFVQQQAKKVLGAPAARVKGRVRGMSGTL
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
SGGTAASAKATFDAVAQDLSLVAILKDFFALTPGFKGPKQPAGNKPVYEEDLQSWAAPFM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MALINTRNVHRSNMLMGFPYGQDFVYDEMVLTGAGEKGEANAKKVMAANAEKTGPNAPKP
HHHHHCCCCCCCCEEEECCCCCCHHECCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCC
GEGPSKEERDNGYYNILFVAIGPDGRQVRATVKGDRDPGYGSTSKMISECAIGLLRDGAS
CCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
VKGGFWTPGAALQDSLIKRLVDNAGLTFTVED
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
TSSKFDLVVYGATGFTGKLVAEYLATQYRHDGSLRWAMAGRSLDKLAAVRDEIGAPADT
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCC
PLIAADASNPASLKAMVAQTRLVLTTVGPYQLYGNELVALCAETGTDYVDLCGEPVWMRQ
CEEEECCCCCHHHHHHHHHHEEEEEECCCHHHHCCHHHHHHHHCCCCHHHHCCCHHHHHH
MIDKHQATAEQSGARIVFSCGFDSVPFELGVYFVQQQAKKVLGAPAARVKGRVRGMSGTL
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
SGGTAASAKATFDAVAQDLSLVAILKDFFALTPGFKGPKQPAGNKPVYEEDLQSWAAPFM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MALINTRNVHRSNMLMGFPYGQDFVYDEMVLTGAGEKGEANAKKVMAANAEKTGPNAPKP
HHHHHCCCCCCCCEEEECCCCCCHHECCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCC
GEGPSKEERDNGYYNILFVAIGPDGRQVRATVKGDRDPGYGSTSKMISECAIGLLRDGAS
CCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
VKGGFWTPGAALQDSLIKRLVDNAGLTFTVED
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]