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The map label for this gene is birA [H]

Identifier: 146341099

GI number: 146341099

Start: 4371313

End: 4372122

Strand: Reverse

Name: birA [H]

Synonym: BRADO4170

Alternate gene names: 146341099

Gene position: 4372122-4371313 (Counterclockwise)

Preceding gene: 146341100

Following gene: 146341098

Centisome position: 58.63

GC content: 67.53

Gene sequence:

>810_bases
ATGACGTTGGCGCTCGGAGCCCGTGCCGCTGCCGGCGGCTACGGGCTCGTCGTCTTCGATCAGGCCGGCTCGACCAATGT
CGAGGCCTTGGTCGCGGCGCGGAACGGCGCGAAAGCGCCTTGCTGGTTCGTGACCACGGAGCAGACGGCGGGGCGCGGCC
GCCGCCATCGACCCTGGATCGCCCCGCGCGGCAACCTGGCGTCCTCCGTGCTCGAAGTGCTCGACGTCATTCCGGCCGTC
GCCGCGACGCTCGGATTTGCGGCCTGCCTTGCGATCGAAAACGCTCTGCGCCAGGTCAGCCTCGAGGCTGTGCTGCGGTC
CGGTGGCAGCCCGGCACTGGATCTCGCGGTGAAATGGCCGAACGACGTGCTCGCGGGCGGACGCAAGATCGTCGGTATGC
TGCTCGAGGCCGAGCAGGTAGCCTCCGGGCTGGCTGTCGTGGCCGGCATCGGCACCAATGTGGTGGCGGCGCCGACCGAT
ACCCCGACACCGGCGGTCTCGCTGCGGGACCTCGGCGTCGAGGTCAGCGCCGAGGACCTGTTCACGGCGCTCTCCGACAA
TTGGGTCGAATATTTCGGCATCTGGAACGCGGGTCGCGGCTTCGGCGACATCCGAAAGCTGTGGCTTGAGCGGGCAGCAG
GGCTCGGTCAGCCCGTCGCGATCAGGTCCGGACATGCTATCATCGAGGGGATTTTCGACACGATCGACGAACAGGGTTGT
ATGCTGGTGCGGACCGCGGAGGGACGATTGGAGCCGATCACGGCCGGTGATGTTCATTTCGGCTCGGTCGCATCCAAGGG
AGCGGTCTAG

Upstream 100 bases:

>100_bases
CACCGTGCTCGCGATCTCCGGCATCTTCAACATCCTGTTCTTCGCCTATCCCGGCCCGCTGGTCAGCGCCGCTGCGGCCG
CGGCGAAGTCGCTGTTCTAG

Downstream 100 bases:

>100_bases
ATGGCACGTCCGGACGAACTGACCTTTGCGCCGCTCGGCGGCGTGGGCGAGATCGGCATGAACCTGTCGATCTACGGCCT
CGGCAACCGCCACCAGCGCT

Product: putative biotin--[acetyl-CoA-carboxylase] synthetase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTLALGARAAAGGYGLVVFDQAGSTNVEALVAARNGAKAPCWFVTTEQTAGRGRRHRPWIAPRGNLASSVLEVLDVIPAV
AATLGFAACLAIENALRQVSLEAVLRSGGSPALDLAVKWPNDVLAGGRKIVGMLLEAEQVASGLAVVAGIGTNVVAAPTD
TPTPAVSLRDLGVEVSAEDLFTALSDNWVEYFGIWNAGRGFGDIRKLWLERAAGLGQPVAIRSGHAIIEGIFDTIDEQGC
MLVRTAEGRLEPITAGDVHFGSVASKGAV

Sequences:

>Translated_269_residues
MTLALGARAAAGGYGLVVFDQAGSTNVEALVAARNGAKAPCWFVTTEQTAGRGRRHRPWIAPRGNLASSVLEVLDVIPAV
AATLGFAACLAIENALRQVSLEAVLRSGGSPALDLAVKWPNDVLAGGRKIVGMLLEAEQVASGLAVVAGIGTNVVAAPTD
TPTPAVSLRDLGVEVSAEDLFTALSDNWVEYFGIWNAGRGFGDIRKLWLERAAGLGQPVAIRSGHAIIEGIFDTIDEQGC
MLVRTAEGRLEPITAGDVHFGSVASKGAV
>Mature_268_residues
TLALGARAAAGGYGLVVFDQAGSTNVEALVAARNGAKAPCWFVTTEQTAGRGRRHRPWIAPRGNLASSVLEVLDVIPAVA
ATLGFAACLAIENALRQVSLEAVLRSGGSPALDLAVKWPNDVLAGGRKIVGMLLEAEQVASGLAVVAGIGTNVVAAPTDT
PTPAVSLRDLGVEVSAEDLFTALSDNWVEYFGIWNAGRGFGDIRKLWLERAAGLGQPVAIRSGHAIIEGIFDTIDEQGCM
LVRTAEGRLEPITAGDVHFGSVASKGAV

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=224, Percent_Identity=25.8928571428571, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 27849; Mature: 27718

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLALGARAAAGGYGLVVFDQAGSTNVEALVAARNGAKAPCWFVTTEQTAGRGRRHRPWI
CEEECCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEECHHCCCCCCCCCCC
APRGNLASSVLEVLDVIPAVAATLGFAACLAIENALRQVSLEAVLRSGGSPALDLAVKWP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
NDVLAGGRKIVGMLLEAEQVASGLAVVAGIGTNVVAAPTDTPTPAVSLRDLGVEVSAEDL
HHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCCCEEHHHCCCEECHHHH
FTALSDNWVEYFGIWNAGRGFGDIRKLWLERAAGLGQPVAIRSGHAIIEGIFDTIDEQGC
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCE
MLVRTAEGRLEPITAGDVHFGSVASKGAV
EEEEECCCCCCCCCCCCEECCCCCCCCCC
>Mature Secondary Structure 
TLALGARAAAGGYGLVVFDQAGSTNVEALVAARNGAKAPCWFVTTEQTAGRGRRHRPWI
EEECCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEECHHCCCCCCCCCCC
APRGNLASSVLEVLDVIPAVAATLGFAACLAIENALRQVSLEAVLRSGGSPALDLAVKWP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
NDVLAGGRKIVGMLLEAEQVASGLAVVAGIGTNVVAAPTDTPTPAVSLRDLGVEVSAEDL
HHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCCCEEHHHCCCEECHHHH
FTALSDNWVEYFGIWNAGRGFGDIRKLWLERAAGLGQPVAIRSGHAIIEGIFDTIDEQGC
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCE
MLVRTAEGRLEPITAGDVHFGSVASKGAV
EEEEECCCCCCCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]