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The map label for this gene is 146341098

Identifier: 146341098

GI number: 146341098

Start: 4369642

End: 4371312

Strand: Reverse

Name: 146341098

Synonym: BRADO4169

Alternate gene names: NA

Gene position: 4371312-4369642 (Counterclockwise)

Preceding gene: 146341099

Following gene: 146341097

Centisome position: 58.62

GC content: 66.49

Gene sequence:

>1671_bases
ATGGCACGTCCGGACGAACTGACCTTTGCGCCGCTCGGCGGCGTGGGCGAGATCGGCATGAACCTGTCGATCTACGGCCT
CGGCAACCGCCACCAGCGCTCCTGGCTCGCGATCGATCTCGGCGTCTCCTTCGGCGACGAGGAGCATCTGCCGGGCATCG
ATCTGATCATGCCGGACGTGAGCTTCCTGGAGAAGGAGGGCAAGAACCTCGTCGGCCTGGTGCTGACCCACGCGCATGAA
GACCATTTCGGCGCGATCATCGATCTCTGGCCGCGGCTGAAATGCCCGATCTACGCGACCAAGTTCAGCGCGGCGTTGTT
CGAGGCGAAGTGCGAAGCCGAGCGGTTGCCGGCCAAGATTCCGGTCAAGGTGATCCCGTCGGGCGGCCGCGTCGATATCG
GCCCGTTCAACGTCGAGTTCATCCCGGTCGCGCATTCGATTCCGGAATCGCATGCGCTCGCCATCCACACCGAGGTCGGC
ACTGTCCTGCACACCGGCGACTGGAAGATCGATCCGACGCCGGTGCTGGGCGCGCCGACCGACGAGAAGCGGCTGCGCGA
GCTCGGCGATGCCGGGCTGCTCGCGCTCATCGGCGACTCGACCAACGCTGTGCGCGAGGGACGTTCGCCGTCCGAGGCCG
AAGTCGCCAAGAGCATCGCCAAGCTGGTCAAGGAAGCGAAGGGGCGCGTCGCCGTCACTACCTTCGCCTCCAACGTGGCG
CGTATTCGCGCCGTCGCCGATGCGGCACGCGAGGCCGAGCGCGAGGTCGTCATCGTCGGCCGCGCCATGGAGCGCGTTGT
GCAGGTGGCGCGCGAGACCGGCTATCTCGACGGCGTGCAGAACTTCCGCGGCATGGATCTCTACGGCCACTTTCCGCCGG
ACAAGGTGCTGGCGCTTTGCACCGGCAGCCAGGGCGAGCCGCGCGCGGCGCTGGCGCGTATCGCCAATGACGATCATCCG
CTGGTCACGCTCAACAAGGGCGACACGGTCATCTTCTCCTCGCGCACCATCCCCGGCAATGAGAAGGCCGTCGGCGCGGT
GATCAATGGACTGGTGCAGCAGGGCATTGAGATCATCACCGATCGCGATCATCTGGTGCACGTTTCCGGCCATCCGCGCC
GCGACGAGCTGCGCGACATGATCGCCTGGACGCGGCCTCAGCTCTTGATCCCCGTCCATGGCGAGGCGCTGCACCTCAAC
GAGCACGCCAAGCTGGCGCGCGCCTGCGGCGTGCCGAGGGTCATCACCTGCCGCAATGGCGATCTGGTCAAGCTTGGGCC
AGGCGACCCCGGCATCATCGACGAACTGCCATCGGGCCGGCTCTACAAGGACGGTACCATCCTCGAGGACTCGAAGTCGC
GCGCCGTTGTCGAGCGCCGCAAGATGAGTTTTGCCGGCTGCATCTTCGTGGCCATGGCCGTCACCGAGAAGGGCGAGCTC
GCCGACGATCCCGAAGTCGACATGGTCGGCATTCCCGAGAAGACGACGGCGGGCGAGCCGATGGACGACATCGTGTTCGA
CGCCGTGGTCTCGACCTTCGAAGGCCTGCCGCGGGCGCGCCGGCGTGATCCGGACGCTGCGGCCGAGTCGGTGCGGCGCG
CGGTGCGCTCCGCGGTCAACGAGCAGTGGGGCAAGAAACCGATCTGCCTCGTTCACGTATTGGAAGTCTGA

Upstream 100 bases:

>100_bases
ACAGGGTTGTATGCTGGTGCGGACCGCGGAGGGACGATTGGAGCCGATCACGGCCGGTGATGTTCATTTCGGCTCGGTCG
CATCCAAGGGAGCGGTCTAG

Downstream 100 bases:

>100_bases
GCAAGCAAGGCCGATCGAACGGCCGCGATACAAGAGTGGAGGATGTCATGCTGGGCCGGCTCAATCACGTCGCGATCGCG
GTCAAGGACGCGGAGAAGGC

Product: metallo-beta-lactamase family hydrolase

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MARPDELTFAPLGGVGEIGMNLSIYGLGNRHQRSWLAIDLGVSFGDEEHLPGIDLIMPDVSFLEKEGKNLVGLVLTHAHE
DHFGAIIDLWPRLKCPIYATKFSAALFEAKCEAERLPAKIPVKVIPSGGRVDIGPFNVEFIPVAHSIPESHALAIHTEVG
TVLHTGDWKIDPTPVLGAPTDEKRLRELGDAGLLALIGDSTNAVREGRSPSEAEVAKSIAKLVKEAKGRVAVTTFASNVA
RIRAVADAAREAEREVVIVGRAMERVVQVARETGYLDGVQNFRGMDLYGHFPPDKVLALCTGSQGEPRAALARIANDDHP
LVTLNKGDTVIFSSRTIPGNEKAVGAVINGLVQQGIEIITDRDHLVHVSGHPRRDELRDMIAWTRPQLLIPVHGEALHLN
EHAKLARACGVPRVITCRNGDLVKLGPGDPGIIDELPSGRLYKDGTILEDSKSRAVVERRKMSFAGCIFVAMAVTEKGEL
ADDPEVDMVGIPEKTTAGEPMDDIVFDAVVSTFEGLPRARRRDPDAAAESVRRAVRSAVNEQWGKKPICLVHVLEV

Sequences:

>Translated_556_residues
MARPDELTFAPLGGVGEIGMNLSIYGLGNRHQRSWLAIDLGVSFGDEEHLPGIDLIMPDVSFLEKEGKNLVGLVLTHAHE
DHFGAIIDLWPRLKCPIYATKFSAALFEAKCEAERLPAKIPVKVIPSGGRVDIGPFNVEFIPVAHSIPESHALAIHTEVG
TVLHTGDWKIDPTPVLGAPTDEKRLRELGDAGLLALIGDSTNAVREGRSPSEAEVAKSIAKLVKEAKGRVAVTTFASNVA
RIRAVADAAREAEREVVIVGRAMERVVQVARETGYLDGVQNFRGMDLYGHFPPDKVLALCTGSQGEPRAALARIANDDHP
LVTLNKGDTVIFSSRTIPGNEKAVGAVINGLVQQGIEIITDRDHLVHVSGHPRRDELRDMIAWTRPQLLIPVHGEALHLN
EHAKLARACGVPRVITCRNGDLVKLGPGDPGIIDELPSGRLYKDGTILEDSKSRAVVERRKMSFAGCIFVAMAVTEKGEL
ADDPEVDMVGIPEKTTAGEPMDDIVFDAVVSTFEGLPRARRRDPDAAAESVRRAVRSAVNEQWGKKPICLVHVLEV
>Mature_555_residues
ARPDELTFAPLGGVGEIGMNLSIYGLGNRHQRSWLAIDLGVSFGDEEHLPGIDLIMPDVSFLEKEGKNLVGLVLTHAHED
HFGAIIDLWPRLKCPIYATKFSAALFEAKCEAERLPAKIPVKVIPSGGRVDIGPFNVEFIPVAHSIPESHALAIHTEVGT
VLHTGDWKIDPTPVLGAPTDEKRLRELGDAGLLALIGDSTNAVREGRSPSEAEVAKSIAKLVKEAKGRVAVTTFASNVAR
IRAVADAAREAEREVVIVGRAMERVVQVARETGYLDGVQNFRGMDLYGHFPPDKVLALCTGSQGEPRAALARIANDDHPL
VTLNKGDTVIFSSRTIPGNEKAVGAVINGLVQQGIEIITDRDHLVHVSGHPRRDELRDMIAWTRPQLLIPVHGEALHLNE
HAKLARACGVPRVITCRNGDLVKLGPGDPGIIDELPSGRLYKDGTILEDSKSRAVVERRKMSFAGCIFVAMAVTEKGELA
DDPEVDMVGIPEKTTAGEPMDDIVFDAVVSTFEGLPRARRRDPDAAAESVRRAVRSAVNEQWGKKPICLVHVLEV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 60229; Mature: 60098

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPDELTFAPLGGVGEIGMNLSIYGLGNRHQRSWLAIDLGVSFGDEEHLPGIDLIMPDV
CCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCH
SFLEKEGKNLVGLVLTHAHEDHFGAIIDLWPRLKCPIYATKFSAALFEAKCEAERLPAKI
HHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
PVKVIPSGGRVDIGPFNVEFIPVAHSIPESHALAIHTEVGTVLHTGDWKIDPTPVLGAPT
CEEEECCCCEEECCCCCEEEEEEECCCCCCCEEEEEECCCEEEECCCCEECCCCCCCCCC
DEKRLRELGDAGLLALIGDSTNAVREGRSPSEAEVAKSIAKLVKEAKGRVAVTTFASNVA
CHHHHHHCCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHH
RIRAVADAAREAEREVVIVGRAMERVVQVARETGYLDGVQNFRGMDLYGHFPPDKVLALC
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCHHHHHCCCCCCEECCCCHHHEEEEE
TGSQGEPRAALARIANDDHPLVTLNKGDTVIFSSRTIPGNEKAVGAVINGLVQQGIEIIT
ECCCCCCHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHEEE
DRDHLVHVSGHPRRDELRDMIAWTRPQLLIPVHGEALHLNEHAKLARACGVPRVITCRNG
CCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCEEECCHHHHHHHHCCCCEEEEECCC
DLVKLGPGDPGIIDELPSGRLYKDGTILEDSKSRAVVERRKMSFAGCIFVAMAVTEKGEL
CEEEECCCCCCHHCCCCCCCEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDPEVDMVGIPEKTTAGEPMDDIVFDAVVSTFEGLPRARRRDPDAAAESVRRAVRSAVN
CCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHH
EQWGKKPICLVHVLEV
HHHCCCCEEEEEEECC
>Mature Secondary Structure 
ARPDELTFAPLGGVGEIGMNLSIYGLGNRHQRSWLAIDLGVSFGDEEHLPGIDLIMPDV
CCCCCEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCH
SFLEKEGKNLVGLVLTHAHEDHFGAIIDLWPRLKCPIYATKFSAALFEAKCEAERLPAKI
HHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
PVKVIPSGGRVDIGPFNVEFIPVAHSIPESHALAIHTEVGTVLHTGDWKIDPTPVLGAPT
CEEEECCCCEEECCCCCEEEEEEECCCCCCCEEEEEECCCEEEECCCCEECCCCCCCCCC
DEKRLRELGDAGLLALIGDSTNAVREGRSPSEAEVAKSIAKLVKEAKGRVAVTTFASNVA
CHHHHHHCCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHH
RIRAVADAAREAEREVVIVGRAMERVVQVARETGYLDGVQNFRGMDLYGHFPPDKVLALC
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCHHHHHCCCCCCEECCCCHHHEEEEE
TGSQGEPRAALARIANDDHPLVTLNKGDTVIFSSRTIPGNEKAVGAVINGLVQQGIEIIT
ECCCCCCHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHEEE
DRDHLVHVSGHPRRDELRDMIAWTRPQLLIPVHGEALHLNEHAKLARACGVPRVITCRNG
CCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCEEECCHHHHHHHHCCCCEEEEECCC
DLVKLGPGDPGIIDELPSGRLYKDGTILEDSKSRAVVERRKMSFAGCIFVAMAVTEKGEL
CEEEECCCCCCHHCCCCCCCEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDPEVDMVGIPEKTTAGEPMDDIVFDAVVSTFEGLPRARRRDPDAAAESVRRAVRSAVN
CCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHH
EQWGKKPICLVHVLEV
HHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]