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The map label for this gene is yaeL [C]

Identifier: 146341062

GI number: 146341062

Start: 4329390

End: 4330541

Strand: Reverse

Name: yaeL [C]

Synonym: BRADO4133

Alternate gene names: 146341062

Gene position: 4330541-4329390 (Counterclockwise)

Preceding gene: 146341063

Following gene: 146341061

Centisome position: 58.08

GC content: 61.89

Gene sequence:

>1152_bases
ATGTCCGAAATTTTCCACCATATTTTCAATACGTTGAGCCACGGCCTGCTCGGCACCATCATCCCCTTCCTGTTCGTGCT
CACGATCGTCGTGTTCTTCCACGAGCTCGGCCATTTCTTGATCGCCCGCTGGGCGGGCGTGAAGGTCTTAACGTTTTCGC
TCGGATTTGGTCCTGAGTTGATCGGTTTCAACGACCGCCACAACACGCGCTGGAAGATCTCCGCGATCCCGCTCGGCGGC
TACGTCAAGTTCTTCGGCGATGAATCCGAGGCGTCCACGCCCTCGACCGAGGCGCTTGCCAAGATGACCGAGCAGGAGCG
CGCCGACAGCTTCCACCACAAGACCGTCGGACAGCGCGCCGCGATTGTCGCGGCCGGCCCGATCGCCAATTTCATCCTCG
CCGTCGTCATCTTCGCCGGCATGGCTCTCTACTTCGGCAAGCCGAACACGACACCGCGGGTCGACGCCGTACAGCCGGAC
AGTGTCGCAGCGGCGGCCGGGTTCAAGACCGGCGACGTCATTGCCGCCATTGATGGCCGGGCCATCGAGACCTTCGCCGA
CATGCAGCGCGTGGTGTCGGTGAATGCCGGCTCGGAGCTGAGCTTTTTGATCAAGCGGGACGGCACCGAGCTGACGTTGA
AGGCCACCCCGGCGCTGAAGGAGGTCAAGGACACGTTCGGCAACAGTCACCGCATCGGGGTGCTCGGCATCCAGTACAAC
GCCAAGCCGGACGAATCACGGGCCATCCCGGTCGGGTTCCTCGAATCGATCAAGTTCGGCTTCGAGCAGGTCTGGTTCAT
CATCACCACAACCTTCAAGTTCATCGGCTCGTTGTTCGCGGGAAGCGGCAATGCCGGCGATCTCGGCGGACCGATCCGAA
TCGCCCAGCTGTCGGGGCAGGCGGCGAGCCTCGGGTTCCAGGTCCTGGTCAACTGGTGCGCGATGATCTCCGTCTCGATC
GGGCTGTTGAACCTGTTCCCGGTTCCGCTGCTGGATGGTGGACACCTGCTGTTTTACGGGGTTGAGGCGGTTCGCGGCCG
TCCTTTGTCGGAAAGAGCCCAGGAGATGGGGTTCCGAATCGGCCTCGGACTGGTGCTCATGCTGATGGTCTTTGCGACCT
ATAACGACATCCTCCACCTCGCGGGGTCCTGA

Upstream 100 bases:

>100_bases
CCATGATGCCCGAAAAAGGGCCGCGGGGCTCTTGCCTCAAATCGCCGCAAAAGCATCTTAAAGGGTTGGACGGGCCGCCG
GCCCATCGGGAAGGTTATCG

Downstream 100 bases:

>100_bases
AGTCGGCTTTTTTACGACGTGGCGGATAGGCAACGTTTTGAAACGAACTTGAAAATTCGGAGAAATCCGGCGTTTGCCGT
CCAAGGCAAATTGGTTACAA

Product: putative Zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSEIFHHIFNTLSHGLLGTIIPFLFVLTIVVFFHELGHFLIARWAGVKVLTFSLGFGPELIGFNDRHNTRWKISAIPLGG
YVKFFGDESEASTPSTEALAKMTEQERADSFHHKTVGQRAAIVAAGPIANFILAVVIFAGMALYFGKPNTTPRVDAVQPD
SVAAAAGFKTGDVIAAIDGRAIETFADMQRVVSVNAGSELSFLIKRDGTELTLKATPALKEVKDTFGNSHRIGVLGIQYN
AKPDESRAIPVGFLESIKFGFEQVWFIITTTFKFIGSLFAGSGNAGDLGGPIRIAQLSGQAASLGFQVLVNWCAMISVSI
GLLNLFPVPLLDGGHLLFYGVEAVRGRPLSERAQEMGFRIGLGLVLMLMVFATYNDILHLAGS

Sequences:

>Translated_383_residues
MSEIFHHIFNTLSHGLLGTIIPFLFVLTIVVFFHELGHFLIARWAGVKVLTFSLGFGPELIGFNDRHNTRWKISAIPLGG
YVKFFGDESEASTPSTEALAKMTEQERADSFHHKTVGQRAAIVAAGPIANFILAVVIFAGMALYFGKPNTTPRVDAVQPD
SVAAAAGFKTGDVIAAIDGRAIETFADMQRVVSVNAGSELSFLIKRDGTELTLKATPALKEVKDTFGNSHRIGVLGIQYN
AKPDESRAIPVGFLESIKFGFEQVWFIITTTFKFIGSLFAGSGNAGDLGGPIRIAQLSGQAASLGFQVLVNWCAMISVSI
GLLNLFPVPLLDGGHLLFYGVEAVRGRPLSERAQEMGFRIGLGLVLMLMVFATYNDILHLAGS
>Mature_382_residues
SEIFHHIFNTLSHGLLGTIIPFLFVLTIVVFFHELGHFLIARWAGVKVLTFSLGFGPELIGFNDRHNTRWKISAIPLGGY
VKFFGDESEASTPSTEALAKMTEQERADSFHHKTVGQRAAIVAAGPIANFILAVVIFAGMALYFGKPNTTPRVDAVQPDS
VAAAAGFKTGDVIAAIDGRAIETFADMQRVVSVNAGSELSFLIKRDGTELTLKATPALKEVKDTFGNSHRIGVLGIQYNA
KPDESRAIPVGFLESIKFGFEQVWFIITTTFKFIGSLFAGSGNAGDLGGPIRIAQLSGQAASLGFQVLVNWCAMISVSIG
LLNLFPVPLLDGGHLLFYGVEAVRGRPLSERAQEMGFRIGLGLVLMLMVFATYNDILHLAGS

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=236, Percent_Identity=36.4406779661017, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 41319; Mature: 41188

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIFHHIFNTLSHGLLGTIIPFLFVLTIVVFFHELGHFLIARWAGVKVLTFSLGFGPEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCE
IGFNDRHNTRWKISAIPLGGYVKFFGDESEASTPSTEALAKMTEQERADSFHHKTVGQRA
ECCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
AIVAAGPIANFILAVVIFAGMALYFGKPNTTPRVDAVQPDSVAAAAGFKTGDVIAAIDGR
EEEECCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCC
AIETFADMQRVVSVNAGSELSFLIKRDGTELTLKATPALKEVKDTFGNSHRIGVLGIQYN
HHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHCCCCCEEEEEEEEEC
AKPDESRAIPVGFLESIKFGFEQVWFIITTTFKFIGSLFAGSGNAGDLGGPIRIAQLSGQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
AASLGFQVLVNWCAMISVSIGLLNLFPVPLLDGGHLLFYGVEAVRGRPLSERAQEMGFRI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEHHHHCCCCHHHHHHHCCHHH
GLGLVLMLMVFATYNDILHLAGS
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEIFHHIFNTLSHGLLGTIIPFLFVLTIVVFFHELGHFLIARWAGVKVLTFSLGFGPEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCE
IGFNDRHNTRWKISAIPLGGYVKFFGDESEASTPSTEALAKMTEQERADSFHHKTVGQRA
ECCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
AIVAAGPIANFILAVVIFAGMALYFGKPNTTPRVDAVQPDSVAAAAGFKTGDVIAAIDGR
EEEECCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCC
AIETFADMQRVVSVNAGSELSFLIKRDGTELTLKATPALKEVKDTFGNSHRIGVLGIQYN
HHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHCCCCCEEEEEEEEEC
AKPDESRAIPVGFLESIKFGFEQVWFIITTTFKFIGSLFAGSGNAGDLGGPIRIAQLSGQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
AASLGFQVLVNWCAMISVSIGLLNLFPVPLLDGGHLLFYGVEAVRGRPLSERAQEMGFRI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEHHHHCCCCHHHHHHHCCHHH
GLGLVLMLMVFATYNDILHLAGS
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]