Click here to switch to the map view.

The map label for this gene is moaC [H]

Identifier: 146341040

GI number: 146341040

Start: 4300970

End: 4301467

Strand: Direct

Name: moaC [H]

Synonym: BRADO4111

Alternate gene names: 146341040

Gene position: 4300970-4301467 (Clockwise)

Preceding gene: 146341039

Following gene: 146341041

Centisome position: 57.68

GC content: 65.86

Gene sequence:

>498_bases
GTGACCATGGCCGACACCTCCGACACATCGTCTCTTACTCATATCGACGCGCGCGGCGAGGCGCGCATGGTCGACGTGTC
CGACAAGGCCGCCACCGAGCGCACGGCAACTGCCGAGGGCCGTGTCGTGATGAGCCCGGCGACGCTGGACCTGATCGTGT
CCGGCAACGCCAAGAAGGGCGACGTGCTCGGCACCGCGCGCATCGCCGGCATCATGGCCGCAAAGCGCACCTCCGAGCTC
ATTCCGCTGTGCCACCCGTTGGCGCTGTCGAAGGTCACGGTCGACATCACGACTGACGCCGCCCTGCCCGGCTGCATCGT
CAGCGCCACGGTCAAGGTCACGGGGCCGACCGGCGTCGAGATGGAGGCGCTCACCGCCGTGTCCGTCGCCTGCCTCACGA
TCTACGACATGATCAAGGCCGCCGAGCGCGGAGTTCGTATCGAAGGCATTCATCTGACCGAGAAAATCGGCGGCAAATCC
GGACACTATCGCGTTTGA

Upstream 100 bases:

>100_bases
AGACCTTCCTGGTCGGCGAGAGCCTGATGCGCCAAGCCGACGTCACCGCGGCGACGCGCGCCCTGCTCGCGCGCAACGCC
GCCTCGGCAAGCGCGGCTGA

Downstream 100 bases:

>100_bases
TGGTATCTTGAGCCCACCACAACCTTGAATTAAGTGTTCGCTAACTGATCTTGCTAACCTCACTTCCATTGCAGGCCTGT
AGCTATGGCCCATGGGAGGG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTMADTSDTSSLTHIDARGEARMVDVSDKAATERTATAEGRVVMSPATLDLIVSGNAKKGDVLGTARIAGIMAAKRTSEL
IPLCHPLALSKVTVDITTDAALPGCIVSATVKVTGPTGVEMEALTAVSVACLTIYDMIKAAERGVRIEGIHLTEKIGGKS
GHYRV

Sequences:

>Translated_165_residues
MTMADTSDTSSLTHIDARGEARMVDVSDKAATERTATAEGRVVMSPATLDLIVSGNAKKGDVLGTARIAGIMAAKRTSEL
IPLCHPLALSKVTVDITTDAALPGCIVSATVKVTGPTGVEMEALTAVSVACLTIYDMIKAAERGVRIEGIHLTEKIGGKS
GHYRV
>Mature_164_residues
TMADTSDTSSLTHIDARGEARMVDVSDKAATERTATAEGRVVMSPATLDLIVSGNAKKGDVLGTARIAGIMAAKRTSELI
PLCHPLALSKVTVDITTDAALPGCIVSATVKVTGPTGVEMEALTAVSVACLTIYDMIKAAERGVRIEGIHLTEKIGGKSG
HYRV

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=56.4102564102564, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=161, Percent_Identity=42.2360248447205, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=50.9677419354839, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=50.7042253521127, Blast_Score=124, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17136; Mature: 17005

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMADTSDTSSLTHIDARGEARMVDVSDKAATERTATAEGRVVMSPATLDLIVSGNAKKG
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCC
DVLGTARIAGIMAAKRTSELIPLCHPLALSKVTVDITTDAALPGCIVSATVKVTGPTGVE
CEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEEEEECCCCCC
MEALTAVSVACLTIYDMIKAAERGVRIEGIHLTEKIGGKSGHYRV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCCCCCCCC
>Mature Secondary Structure 
TMADTSDTSSLTHIDARGEARMVDVSDKAATERTATAEGRVVMSPATLDLIVSGNAKKG
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCC
DVLGTARIAGIMAAKRTSELIPLCHPLALSKVTVDITTDAALPGCIVSATVKVTGPTGVE
CEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEEEEECCCCCC
MEALTAVSVACLTIYDMIKAAERGVRIEGIHLTEKIGGKSGHYRV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9061023; 12597275 [H]