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The map label for this gene is thrC [H]

Identifier: 146341011

GI number: 146341011

Start: 4271151

End: 4272392

Strand: Reverse

Name: thrC [H]

Synonym: BRADO4082

Alternate gene names: 146341011

Gene position: 4272392-4271151 (Counterclockwise)

Preceding gene: 146341012

Following gene: 146341010

Centisome position: 57.3

GC content: 66.18

Gene sequence:

>1242_bases
ATGAAATCCAGCGACAATCTCACCACCGAGCGCCCGACCTTCGTCACCCATCTCGAATGCGCGATGGTCGGCGACCATTA
TCCGGCGGACCAGGTCCACAACCTCTCAAAGGCCGGCAAGCCGCTGCTGGTGCGCTACGATCTCGCGGGCGTGAAACAGG
CGCTGACCAAGGACGCGCTGGCGCAGCGGCCCGCGGACATGTGGCGCTATCGCGAGCTGCTGCCGGTGCGCAAATGCCAG
GACATCGTCAGCCTCGGCGAGGTCATGACGCCGCTGATCAATCTGCCGAAGCTGGCGAAGACACTCGGCGGCGGCGAGAT
CATCGTCAAGGATGAGGGGCGGCTGCCGACCGGCTCGTTCAAGGCGCGCGGCCTCGTGATGGCGGTGTCGATGGGCAAGG
CGCTCGGCATCACCCACATGGCGATGCCGACCAACGGCAATGCGGGGGCAGCGCTCGCGGCCTACGCGACGTCCTGCGGC
ATCAAGACCACGATCTTTTGCCCGGCCGATACGCCGGAGGTGAACGTCAGCGAGATCGAGCTGCAGGGCGCGACCGTCTA
TCGCGTCAACGGCCTCATTGATGATTGCGGCAAGATCGTCGGGGAGGGGAAGGCCAAGGTCGGCTGGTTCGATACCTCGA
CCCTGAAGGAGCCGTACCGGATCGAAGGCAAGAAGACGATGGGCCTGGAGCTCGCCGAGCAGCTCGGCTGGGACGTGCCC
GACGTGATCTTCTATCCGACCGGCGGCGGCACCGGCCTGATCGGCATGTGGAAGGGGTTCGACGAGCTGGAGAAGATCGG
CTTCATCGGTTCGAAGCGCCCGCGCATGGTCGCGGTGCAAGCCTCCGGCTGCGCGCCGATGGTGCGCGCCTACGAAGCCG
GCGTCGAGCACGCGACGCGCTGGGAGGATGCGCATACGATCGCCTCGGGAATCCGCGTGCCGCAGGCGGTCGGCGACTTC
CTCATCCTACGCGCCGTACGCGAGAGCGGCGGCTTTGCCATTGCGGTCGATGACGACGCGATTTCGGCCGGTCTCAACGA
GGTCGCGCGCGAGGAGGGGCTGCTGCTCTGCCCCGAGGGCGCTGCGACCTACGCGGCCTACAAGCAGAGCCTCGCCGACG
GGCGCGTGACGAAGACCGACCGCGTCATGCTGTTCAACTGCGCCACCGGACTCAAATATCCGCTGCCGAAGGTCGAGCGC
ACGCTCGATCGCCACCAGCCGATCGACTACACTCAGTTCTGA

Upstream 100 bases:

>100_bases
GCAATCCAGGGGCCCAGGGTGAGACTCTGGATTGCTTCGTCGCTTCGCTCCTCGCAATGACGAACAACAAACTCCGATCG
CTGCAGGAAAGAACAACAAC

Downstream 100 bases:

>100_bases
CCGGACGGTCGGCATTGCGGCCTGGCGCCTGATCGTCTGACAACAAGGATCAGGCCGCGCGGGGAGGACGTCATGCGACG
CCTGTTCGGCGCTGTGGCGA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKSSDNLTTERPTFVTHLECAMVGDHYPADQVHNLSKAGKPLLVRYDLAGVKQALTKDALAQRPADMWRYRELLPVRKCQ
DIVSLGEVMTPLINLPKLAKTLGGGEIIVKDEGRLPTGSFKARGLVMAVSMGKALGITHMAMPTNGNAGAALAAYATSCG
IKTTIFCPADTPEVNVSEIELQGATVYRVNGLIDDCGKIVGEGKAKVGWFDTSTLKEPYRIEGKKTMGLELAEQLGWDVP
DVIFYPTGGGTGLIGMWKGFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATRWEDAHTIASGIRVPQAVGDF
LILRAVRESGGFAIAVDDDAISAGLNEVAREEGLLLCPEGAATYAAYKQSLADGRVTKTDRVMLFNCATGLKYPLPKVER
TLDRHQPIDYTQF

Sequences:

>Translated_413_residues
MKSSDNLTTERPTFVTHLECAMVGDHYPADQVHNLSKAGKPLLVRYDLAGVKQALTKDALAQRPADMWRYRELLPVRKCQ
DIVSLGEVMTPLINLPKLAKTLGGGEIIVKDEGRLPTGSFKARGLVMAVSMGKALGITHMAMPTNGNAGAALAAYATSCG
IKTTIFCPADTPEVNVSEIELQGATVYRVNGLIDDCGKIVGEGKAKVGWFDTSTLKEPYRIEGKKTMGLELAEQLGWDVP
DVIFYPTGGGTGLIGMWKGFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATRWEDAHTIASGIRVPQAVGDF
LILRAVRESGGFAIAVDDDAISAGLNEVAREEGLLLCPEGAATYAAYKQSLADGRVTKTDRVMLFNCATGLKYPLPKVER
TLDRHQPIDYTQF
>Mature_413_residues
MKSSDNLTTERPTFVTHLECAMVGDHYPADQVHNLSKAGKPLLVRYDLAGVKQALTKDALAQRPADMWRYRELLPVRKCQ
DIVSLGEVMTPLINLPKLAKTLGGGEIIVKDEGRLPTGSFKARGLVMAVSMGKALGITHMAMPTNGNAGAALAAYATSCG
IKTTIFCPADTPEVNVSEIELQGATVYRVNGLIDDCGKIVGEGKAKVGWFDTSTLKEPYRIEGKKTMGLELAEQLGWDVP
DVIFYPTGGGTGLIGMWKGFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATRWEDAHTIASGIRVPQAVGDF
LILRAVRESGGFAIAVDDDAISAGLNEVAREEGLLLCPEGAATYAAYKQSLADGRVTKTDRVMLFNCATGLKYPLPKVER
TLDRHQPIDYTQF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 44591; Mature: 44591

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSDNLTTERPTFVTHLECAMVGDHYPADQVHNLSKAGKPLLVRYDLAGVKQALTKDAL
CCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
AQRPADMWRYRELLPVRKCQDIVSLGEVMTPLINLPKLAKTLGGGEIIVKDEGRLPTGSF
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCCC
KARGLVMAVSMGKALGITHMAMPTNGNAGAALAAYATSCGIKTTIFCPADTPEVNVSEIE
CCCCEEEEEECCCHHCEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEE
LQGATVYRVNGLIDDCGKIVGEGKAKVGWFDTSTLKEPYRIEGKKTMGLELAEQLGWDVP
ECCCEEEEECCHHHHHHHHHCCCCCEEEEEEHHHCCCCEEECCCCCHHHHHHHHCCCCCC
DVIFYPTGGGTGLIGMWKGFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATR
CEEEEECCCCCCEEHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
WEDAHTIASGIRVPQAVGDFLILRAVRESGGFAIAVDDDAISAGLNEVAREEGLLLCPEG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCEECCCC
AATYAAYKQSLADGRVTKTDRVMLFNCATGLKYPLPKVERTLDRHQPIDYTQF
CHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSSDNLTTERPTFVTHLECAMVGDHYPADQVHNLSKAGKPLLVRYDLAGVKQALTKDAL
CCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
AQRPADMWRYRELLPVRKCQDIVSLGEVMTPLINLPKLAKTLGGGEIIVKDEGRLPTGSF
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCCC
KARGLVMAVSMGKALGITHMAMPTNGNAGAALAAYATSCGIKTTIFCPADTPEVNVSEIE
CCCCEEEEEECCCHHCEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEE
LQGATVYRVNGLIDDCGKIVGEGKAKVGWFDTSTLKEPYRIEGKKTMGLELAEQLGWDVP
ECCCEEEEECCHHHHHHHHHCCCCCEEEEEEHHHCCCCEEECCCCCHHHHHHHHCCCCCC
DVIFYPTGGGTGLIGMWKGFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATR
CEEEEECCCCCCEEHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
WEDAHTIASGIRVPQAVGDFLILRAVRESGGFAIAVDDDAISAGLNEVAREEGLLLCPEG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCEECCCC
AATYAAYKQSLADGRVTKTDRVMLFNCATGLKYPLPKVERTLDRHQPIDYTQF
CHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]