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The map label for this gene is tfdA [H]

Identifier: 146340960

GI number: 146340960

Start: 4221182

End: 4221874

Strand: Direct

Name: tfdA [H]

Synonym: BRADO4031

Alternate gene names: 146340960

Gene position: 4221182-4221874 (Clockwise)

Preceding gene: 146340959

Following gene: 146340967

Centisome position: 56.61

GC content: 65.51

Gene sequence:

>693_bases
GTGAATCACAGAAGCAACGTTGCGCGAAGCGCCGAAAGCAGCCTCGTCCAGGTACTCCCGACCGGCAAGGCGCTTGGTGC
CGAGGTCTGCAATGTCGACCTCAGATCCTTCGACGATTGGGCATTCGCCTCCTTCATGCGCGCGCTGCTCAAACACCAGG
TGCTGCTCGTGCGCTGGCAGCGTCTCACCGACCGCGACATCGCGGCGTTCAGCCGGCGCTTCGGTCATGCCGATCTTCAC
TACACGTCGTATGGCACGACGCGGGGCGAGAGCCTGTCGTTCTGCAGCCTGTACGCGGCGTATGACGCGCTGTCGCCGGC
GATGCGCAGCCGCGTCGCTCATCTGAAGGTTCGTCAGCGCACGATCGACACCGCCGATGATGGTCGCCGCACCATCTTTG
CGGGTCCGGTGCACCCGCTGGTCGGCCTGCACGCCGACACCGGCCGCTCGATGCTGGCGCTTGGACAGCGCCGCCATTCC
TATGTGGTCGGCCTCGAGCAGGACGAGTCTGAAGCGCTACTCAATGACCTCTGGCAGCTCGCCGAACGTCCCGAGTTCAG
TTGGACTCACACCTGCCGTGGCGGCGACCTCATCGTGTGGGACACGCGTTGCACGATCCACCGGCACGAGGCGCCGGACA
TGCCGCGACTGCTGCACAGCCCGCCGCTTTGGAACGCCATGCCGACCGCCTGA

Upstream 100 bases:

>100_bases
CGTGCCGCGATCATCCCGCGAATTGCCTCCGAGCCGAAACAACCCCGACAAATTACAGTGGTTGATTGGCAGCGCTGGTG
AAACTTGGGAGACGACGCAC

Downstream 100 bases:

>100_bases
CGCGGCCGTCCCCCTTCAACGACCGCGAAAGCTCCCCGTTCTGGCCGCGCGCCACAGCGTCCAGAGCGTCGCGAGACGCG
AGCGCGGCTGCGGCAGGAAC

Product: putative dioxygenase taurine dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: 2,4-D dioxygenase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNHRSNVARSAESSLVQVLPTGKALGAEVCNVDLRSFDDWAFASFMRALLKHQVLLVRWQRLTDRDIAAFSRRFGHADLH
YTSYGTTRGESLSFCSLYAAYDALSPAMRSRVAHLKVRQRTIDTADDGRRTIFAGPVHPLVGLHADTGRSMLALGQRRHS
YVVGLEQDESEALLNDLWQLAERPEFSWTHTCRGGDLIVWDTRCTIHRHEAPDMPRLLHSPPLWNAMPTA

Sequences:

>Translated_230_residues
MNHRSNVARSAESSLVQVLPTGKALGAEVCNVDLRSFDDWAFASFMRALLKHQVLLVRWQRLTDRDIAAFSRRFGHADLH
YTSYGTTRGESLSFCSLYAAYDALSPAMRSRVAHLKVRQRTIDTADDGRRTIFAGPVHPLVGLHADTGRSMLALGQRRHS
YVVGLEQDESEALLNDLWQLAERPEFSWTHTCRGGDLIVWDTRCTIHRHEAPDMPRLLHSPPLWNAMPTA
>Mature_230_residues
MNHRSNVARSAESSLVQVLPTGKALGAEVCNVDLRSFDDWAFASFMRALLKHQVLLVRWQRLTDRDIAAFSRRFGHADLH
YTSYGTTRGESLSFCSLYAAYDALSPAMRSRVAHLKVRQRTIDTADDGRRTIFAGPVHPLVGLHADTGRSMLALGQRRHS
YVVGLEQDESEALLNDLWQLAERPEFSWTHTCRGGDLIVWDTRCTIHRHEAPDMPRLLHSPPLWNAMPTA

Specific function: Involved in degradation of the herbicide 2,4- dichlorophenoxyacetic acid (2,4-D). Is also able to degrade 2- methyl-4-chlorophenoxyacetic acid and 3-chlorobenzoic acid [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 25989; Mature: 25989

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRSNVARSAESSLVQVLPTGKALGAEVCNVDLRSFDDWAFASFMRALLKHQVLLVRWQ
CCCHHHHHHHHHHHHHEEECCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLTDRDIAAFSRRFGHADLHYTSYGTTRGESLSFCSLYAAYDALSPAMRSRVAHLKVRQR
HCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
TIDTADDGRRTIFAGPVHPLVGLHADTGRSMLALGQRRHSYVVGLEQDESEALLNDLWQL
HCCCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
AERPEFSWTHTCRGGDLIVWDTRCTIHRHEAPDMPRLLHSPPLWNAMPTA
HCCCCCCEEEECCCCCEEEECCEEEEECCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNHRSNVARSAESSLVQVLPTGKALGAEVCNVDLRSFDDWAFASFMRALLKHQVLLVRWQ
CCCHHHHHHHHHHHHHEEECCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLTDRDIAAFSRRFGHADLHYTSYGTTRGESLSFCSLYAAYDALSPAMRSRVAHLKVRQR
HCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
TIDTADDGRRTIFAGPVHPLVGLHADTGRSMLALGQRRHSYVVGLEQDESEALLNDLWQL
HCCCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
AERPEFSWTHTCRGGDLIVWDTRCTIHRHEAPDMPRLLHSPPLWNAMPTA
HCCCCCCEEEECCCCCEEEECCEEEEECCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036764; 10777523; 11457355; 11955067 [H]