Click here to switch to the map view.

The map label for this gene is coaD

Identifier: 146340926

GI number: 146340926

Start: 4187382

End: 4187876

Strand: Reverse

Name: coaD

Synonym: BRADO3997

Alternate gene names: 146340926

Gene position: 4187876-4187382 (Counterclockwise)

Preceding gene: 146340928

Following gene: 146340925

Centisome position: 56.16

GC content: 66.46

Gene sequence:

>495_bases
ATGCAACGCATTGCGCTCTATCCGGGCTCGTTCGATCCCGTCACCAACGGCCATCTCGACGTGGTCCGCCAAGCCGTCCA
TCTCTGCGACAAGCTCATCGTCGCGGTCGGCGTGCATCACGGCAAGAAGCCGCTGTTCTCGACCGAGGAGCGGCTGGCGA
TGGCCCATGAGGTGTTCGGCCCGGTCGCGTCCGCAGCCGGCTGCGCGTTCGACGCCTCGACCTATGACAATCTCACGGTG
ACGGCAGCGCAGCAGGCGGGCGCGATCCTGATGATCCGCGGCCTGCGCGACGGTACCGATCTCGACTACGAGATGCAACT
CGCCGGCATGAACCAGACGATGGCGCCGTCGATCCAGACCGTGTTCGTGCCGGCGTCCGTCCCGGTGCGTCCGATCACGG
CGAGTCTCGTCCGCCAGATCGCCGCGATGGGCGGCGAGATCTCGCATTTCGTCCCGCCGTCGGTGGTGGCCCCGCTGAAA
GCCAAGTTCGCCTGA

Upstream 100 bases:

>100_bases
GCGTCGTCGCAGCGCAAACAACCGGGTACCGCCATCACAGCCGCGCCAGCCCGGGCGTCGGCGGCTTGCCCGGCTGTTCC
GGGCGGTATAGGACGGGCGC

Downstream 100 bases:

>100_bases
CGGTCCGGCGTCTTTCTAGCTCATTCCTCTCACCTCTCATCTCATCGGAGTTGCCATGATCCGCGCTCTCGCCTTCGTCT
TCGCTCTCGTGTTCGCGGTC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MQRIALYPGSFDPVTNGHLDVVRQAVHLCDKLIVAVGVHHGKKPLFSTEERLAMAHEVFGPVASAAGCAFDASTYDNLTV
TAAQQAGAILMIRGLRDGTDLDYEMQLAGMNQTMAPSIQTVFVPASVPVRPITASLVRQIAAMGGEISHFVPPSVVAPLK
AKFA

Sequences:

>Translated_164_residues
MQRIALYPGSFDPVTNGHLDVVRQAVHLCDKLIVAVGVHHGKKPLFSTEERLAMAHEVFGPVASAAGCAFDASTYDNLTV
TAAQQAGAILMIRGLRDGTDLDYEMQLAGMNQTMAPSIQTVFVPASVPVRPITASLVRQIAAMGGEISHFVPPSVVAPLK
AKFA
>Mature_164_residues
MQRIALYPGSFDPVTNGHLDVVRQAVHLCDKLIVAVGVHHGKKPLFSTEERLAMAHEVFGPVASAAGCAFDASTYDNLTV
TAAQQAGAILMIRGLRDGTDLDYEMQLAGMNQTMAPSIQTVFVPASVPVRPITASLVRQIAAMGGEISHFVPPSVVAPLK
AKFA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=164, Percent_Identity=39.6341463414634, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BRASO (A4YV23)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001205974.1
- ProteinModelPortal:   A4YV23
- SMR:   A4YV23
- STRING:   A4YV23
- GeneID:   5116899
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO3997
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   BSP376:BRADO3997-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17395; Mature: 17395

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIALYPGSFDPVTNGHLDVVRQAVHLCDKLIVAVGVHHGKKPLFSTEERLAMAHEVFG
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
PVASAAGCAFDASTYDNLTVTAAQQAGAILMIRGLRDGTDLDYEMQLAGMNQTMAPSIQT
HHHHHCCCEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCEEE
VFVPASVPVRPITASLVRQIAAMGGEISHFVPPSVVAPLKAKFA
EEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHCCC
>Mature Secondary Structure
MQRIALYPGSFDPVTNGHLDVVRQAVHLCDKLIVAVGVHHGKKPLFSTEERLAMAHEVFG
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
PVASAAGCAFDASTYDNLTVTAAQQAGAILMIRGLRDGTDLDYEMQLAGMNQTMAPSIQT
HHHHHCCCEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCEEE
VFVPASVPVRPITASLVRQIAAMGGEISHFVPPSVVAPLKAKFA
EEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA