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The map label for this gene is atoS [C]

Identifier: 146340912

GI number: 146340912

Start: 4174133

End: 4175932

Strand: Reverse

Name: atoS [C]

Synonym: BRADO3981

Alternate gene names: 146340912

Gene position: 4175932-4174133 (Counterclockwise)

Preceding gene: 146340913

Following gene: 146340908

Centisome position: 56.0

GC content: 64.78

Gene sequence:

>1800_bases
ATGCTGCAGACGCCGTCCCATCGCATGCTCCTGGTTGCTGACGATGCGTTCGATCCGTCGCAGGTGTTGAGACGTCTGTT
TGCCGCGCATCAACCGCCGATCGATCTCTGTCGCGTGCTGGATCTCGGCGGCGCGCGCGACCGTCTGGCCGCGAGCCGCT
ACGACTCGGTGATGCTCAGCGCCGCCGCGATCGCAGACCAGGAGGTCGACGCCGTATCGATCCTGCGGGAGATGTCGGTC
GCTGCCCCCCTGGTCATGATCGGCGGCGAGCCGGATTCGGCCTCCGGCGTCCAGCCGTTGCGCGCAGGAGCCCGCGGCTT
GAACAGCCAAGCAGTGGTCGATTCGGGTCTTCAGTTCGAGCAGCTCCTCGAGGTGTTGCCGGACGCCTTGATCGTGCTGA
ACGCCCGGCAAGAGGTCGAATTCGTCAATAGGGCGGCGCATCGGCTGTTCGGCAAGGCGCAACAGGATTTCATCGGCGAG
CGCGTCAGCTTTTCGGTGACGGAGAACGAGGTCGCCGAGATCGAGGTCTACCGCGACAAGGAGCTGCGGTGCTGCGAGGT
TCGGATGACGCCGTGCAAATGGAAGTCGCAGGACGCGCAGCTCTTGCTCATTCACGACGTCACGGAGCGGAAGAGGCTCA
ACGAGCAGCTGCGCCAGTCGCAGAAGATGGAGGCCGTCGGCGTGCTCGCCGGCGGCATCGCTCACGATTTCAACAATCTG
CTTCTCGTCATGATGATCTATGCGGAGATGATCCGCGATGAAGCCGCCACCGACGATCCACGGCTGTCGGACGTGCTCGA
GATCATCAGGGCTGTCGATCGCGGCCGCGCCCTCACGCAGCAACTGCTCGCATTCTCGCGCAAGCAGCCGTTGCGCCTGG
CGGTGCTCGACCTCGGGGCGGTGATGGCCGAGACCCAGAAGATGCTGCGCCGCCTGCTGCCGAGCAACATCGAGACGATG
GCCATGGTCGAGGGCGACTGCTGGCCGGTGCTGGCCGATCGCGGGCAGATCGAGCAGGTGATCATCAATCTCGCCCTCAA
TGCCCGCGACGCCATGACCTCGGGGGGACGCCTGGAGATCCTGGTCGGCAACCGGACAATTTCGCGCGCGGACGAGGCGG
TGCCGCCGGGCGACTATGTCGTGATGTCCGTGATCGACACCGGGGTCGGGATTTCTCCGGCCGATCTCGAGCTGATCTTC
GATCCGTTCTTCACGACCAAGAAGCGCGGGAGCGGCACCGGACTGGGGCTGTCGACCTGCTACGGGATCATCAATCAGGC
CGGGGGTCATATCAGCGCGGTGAGCAAGGTCGGCGAGGGGACCACGTTCACGGTGCTGCTGCCGCGCGCACCGGCCACGA
CATCCCAGGAACCCGATCAGCCGCTGCCGGTCCACGCCATCTCTGGCCAGGAAACCATTCTGCTCGTCGAGGACAATTAT
CAGGCGCTGCGCGCGACCGAGTTGATGCTGCAGCGCGCGGGCTACGCCGTGCTGACGATGACCAATGGCGACGAGGCCTA
CCGCTTCCTGCAGCAATGCGACCAGGCGATCGACCTTGTGCTGAGCGACGTCGTGATGCCTCAGCTCAGTGGTCCCGAAC
TGGCGCAGCGCCTCGCCGTGACGCACCCTGAGCTGCCTGTCGTCTTCATGACCGGCTACTCGAACGACCCGATCCTTGGG
GAGGCGGGGGATCATCGCATTGGCCGCAGACGTGTGATCTTGAAGCCGTTCAAGCGTGAGGAACTGCTCCTCTTCGTGCG
CGAGGCGATCGACCGCAAGCGCAGTGCCGTCTCCGCGTGA

Upstream 100 bases:

>100_bases
GATCCACGGCATTCTCTCGGGCGCGCCGACCTACACCTTCGCGCGCGAGCGGGACAATCTGGCCGGGATGTTCGAGATGC
CGAGAACGAGGGATTGATTG

Downstream 100 bases:

>100_bases
TCGCCGCATCGCTGGCGTGGAGCGGACGCAGAGGCCCGCGCCTGTCGACGCGGGCCTGCAGGCAGAGCCTGGATCTTCAG
CGGCGGAACGCGCCGCCGAG

Product: putative histidinase kinase-response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MLQTPSHRMLLVADDAFDPSQVLRRLFAAHQPPIDLCRVLDLGGARDRLAASRYDSVMLSAAAIADQEVDAVSILREMSV
AAPLVMIGGEPDSASGVQPLRAGARGLNSQAVVDSGLQFEQLLEVLPDALIVLNARQEVEFVNRAAHRLFGKAQQDFIGE
RVSFSVTENEVAEIEVYRDKELRCCEVRMTPCKWKSQDAQLLLIHDVTERKRLNEQLRQSQKMEAVGVLAGGIAHDFNNL
LLVMMIYAEMIRDEAATDDPRLSDVLEIIRAVDRGRALTQQLLAFSRKQPLRLAVLDLGAVMAETQKMLRRLLPSNIETM
AMVEGDCWPVLADRGQIEQVIINLALNARDAMTSGGRLEILVGNRTISRADEAVPPGDYVVMSVIDTGVGISPADLELIF
DPFFTTKKRGSGTGLGLSTCYGIINQAGGHISAVSKVGEGTTFTVLLPRAPATTSQEPDQPLPVHAISGQETILLVEDNY
QALRATELMLQRAGYAVLTMTNGDEAYRFLQQCDQAIDLVLSDVVMPQLSGPELAQRLAVTHPELPVVFMTGYSNDPILG
EAGDHRIGRRRVILKPFKREELLLFVREAIDRKRSAVSA

Sequences:

>Translated_599_residues
MLQTPSHRMLLVADDAFDPSQVLRRLFAAHQPPIDLCRVLDLGGARDRLAASRYDSVMLSAAAIADQEVDAVSILREMSV
AAPLVMIGGEPDSASGVQPLRAGARGLNSQAVVDSGLQFEQLLEVLPDALIVLNARQEVEFVNRAAHRLFGKAQQDFIGE
RVSFSVTENEVAEIEVYRDKELRCCEVRMTPCKWKSQDAQLLLIHDVTERKRLNEQLRQSQKMEAVGVLAGGIAHDFNNL
LLVMMIYAEMIRDEAATDDPRLSDVLEIIRAVDRGRALTQQLLAFSRKQPLRLAVLDLGAVMAETQKMLRRLLPSNIETM
AMVEGDCWPVLADRGQIEQVIINLALNARDAMTSGGRLEILVGNRTISRADEAVPPGDYVVMSVIDTGVGISPADLELIF
DPFFTTKKRGSGTGLGLSTCYGIINQAGGHISAVSKVGEGTTFTVLLPRAPATTSQEPDQPLPVHAISGQETILLVEDNY
QALRATELMLQRAGYAVLTMTNGDEAYRFLQQCDQAIDLVLSDVVMPQLSGPELAQRLAVTHPELPVVFMTGYSNDPILG
EAGDHRIGRRRVILKPFKREELLLFVREAIDRKRSAVSA
>Mature_599_residues
MLQTPSHRMLLVADDAFDPSQVLRRLFAAHQPPIDLCRVLDLGGARDRLAASRYDSVMLSAAAIADQEVDAVSILREMSV
AAPLVMIGGEPDSASGVQPLRAGARGLNSQAVVDSGLQFEQLLEVLPDALIVLNARQEVEFVNRAAHRLFGKAQQDFIGE
RVSFSVTENEVAEIEVYRDKELRCCEVRMTPCKWKSQDAQLLLIHDVTERKRLNEQLRQSQKMEAVGVLAGGIAHDFNNL
LLVMMIYAEMIRDEAATDDPRLSDVLEIIRAVDRGRALTQQLLAFSRKQPLRLAVLDLGAVMAETQKMLRRLLPSNIETM
AMVEGDCWPVLADRGQIEQVIINLALNARDAMTSGGRLEILVGNRTISRADEAVPPGDYVVMSVIDTGVGISPADLELIF
DPFFTTKKRGSGTGLGLSTCYGIINQAGGHISAVSKVGEGTTFTVLLPRAPATTSQEPDQPLPVHAISGQETILLVEDNY
QALRATELMLQRAGYAVLTMTNGDEAYRFLQQCDQAIDLVLSDVVMPQLSGPELAQRLAVTHPELPVVFMTGYSNDPILG
EAGDHRIGRRRVILKPFKREELLLFVREAIDRKRSAVSA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=363, Percent_Identity=26.9972451790634, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=30.9917355371901, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI48994928, Length=484, Percent_Identity=23.9669421487603, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=30.5019305019305, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=392, Percent_Identity=24.4897959183673, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788713, Length=401, Percent_Identity=22.9426433915212, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=355, Percent_Identity=27.0422535211268, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=287, Percent_Identity=28.2229965156794, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65760; Mature: 65760

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTPSHRMLLVADDAFDPSQVLRRLFAAHQPPIDLCRVLDLGGARDRLAASRYDSVMLS
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAAIADQEVDAVSILREMSVAAPLVMIGGEPDSASGVQPLRAGARGLNSQAVVDSGLQFE
HHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHCCCCHH
QLLEVLPDALIVLNARQEVEFVNRAAHRLFGKAQQDFIGERVSFSVTENEVAEIEVYRDK
HHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECC
ELRCCEVRMTPCKWKSQDAQLLLIHDVTERKRLNEQLRQSQKMEAVGVLAGGIAHDFNNL
CCEEEEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVMMIYAEMIRDEAATDDPRLSDVLEIIRAVDRGRALTQQLLAFSRKQPLRLAVLDLGA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
VMAETQKMLRRLLPSNIETMAMVEGDCWPVLADRGQIEQVIINLALNARDAMTSGGRLEI
HHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHCCHHHHCCCCEEEE
LVGNRTISRADEAVPPGDYVVMSVIDTGVGISPADLELIFDPFFTTKKRGSGTGLGLSTC
EECCCCHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHH
YGIINQAGGHISAVSKVGEGTTFTVLLPRAPATTSQEPDQPLPVHAISGQETILLVEDNY
HHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
QALRATELMLQRAGYAVLTMTNGDEAYRFLQQCDQAIDLVLSDVVMPQLSGPELAQRLAV
HHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
THPELPVVFMTGYSNDPILGEAGDHRIGRRRVILKPFKREELLLFVREAIDRKRSAVSA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLQTPSHRMLLVADDAFDPSQVLRRLFAAHQPPIDLCRVLDLGGARDRLAASRYDSVMLS
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAAIADQEVDAVSILREMSVAAPLVMIGGEPDSASGVQPLRAGARGLNSQAVVDSGLQFE
HHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHCCCCHH
QLLEVLPDALIVLNARQEVEFVNRAAHRLFGKAQQDFIGERVSFSVTENEVAEIEVYRDK
HHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECC
ELRCCEVRMTPCKWKSQDAQLLLIHDVTERKRLNEQLRQSQKMEAVGVLAGGIAHDFNNL
CCEEEEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVMMIYAEMIRDEAATDDPRLSDVLEIIRAVDRGRALTQQLLAFSRKQPLRLAVLDLGA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
VMAETQKMLRRLLPSNIETMAMVEGDCWPVLADRGQIEQVIINLALNARDAMTSGGRLEI
HHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHCCHHHHCCCCEEEE
LVGNRTISRADEAVPPGDYVVMSVIDTGVGISPADLELIFDPFFTTKKRGSGTGLGLSTC
EECCCCHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHH
YGIINQAGGHISAVSKVGEGTTFTVLLPRAPATTSQEPDQPLPVHAISGQETILLVEDNY
HHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEEECCC
QALRATELMLQRAGYAVLTMTNGDEAYRFLQQCDQAIDLVLSDVVMPQLSGPELAQRLAV
HHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
THPELPVVFMTGYSNDPILGEAGDHRIGRRRVILKPFKREELLLFVREAIDRKRSAVSA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA