Click here to switch to the map view.

The map label for this gene is ntrY [H]

Identifier: 146340798

GI number: 146340798

Start: 4029908

End: 4032253

Strand: Reverse

Name: ntrY [H]

Synonym: BRADO3857

Alternate gene names: 146340798

Gene position: 4032253-4029908 (Counterclockwise)

Preceding gene: 146340799

Following gene: 146340797

Centisome position: 54.08

GC content: 65.98

Gene sequence:

>2346_bases
ATGACCAGCGCAGAAGCTTCGGCCACCCCCTTCGACCCATCGTCCGCCGACGCCCGGCGCTGGACCTGGCGCACCTGGCT
GGCGCCGGTGGCGGTCGGGCTCGCGCTGCTGTCGGCGTTTCTGACCTTCATCGTGCTGGTCGGCCTGAGCCCGATCGAGC
CAACCGCCGAGGTCGTCAACACCTTCTACCTGATCGACATCGGTACGATCCTGGTTCTGGTCGGAATCATCGTCCGCGAG
GTCTGGCAGATGATCCAGGCGCGGCGGCGGGGCCGGGCGGCGGCCCGGCTGCACGTCCAGATCGTCAGCCTGTTCTCGGT
CATCGCGGTGCTGCCGGCAGTGATGGTGGCCATGGTCGCCAACGTCGTCATCGACCGCGGCCTGGACCGGCTGTTCTCGG
GCCCAACCCGCGAGGTGATCCAGAACTCGCGCATTATCGCCAGCGCCTACATGCAGGCGCACGCGCAGCTGATCTACGGC
GACATCGTTGGCATGGCAAACGATGTCTCCTATGCACGGCTGCTGTTCGACCAGGACCGCCAGTCGTTCCTGCAGATGCT
CGTCGCCGACGCGGCCACGCGTAACCTGCCGGGCGCCATGATCATCGACAAGAACACCGATCCGATCCTGTCGGCGGAGA
CCGGCGGCATTCCGCTGACCTACGCGCCGCCGCCGCCGGACATGCTGAAGAACGTCGGCGAGGACAAGCCCGAGATCGCC
GTGCTGCCCGACCAGAACAACGTGGCCGCCGTGATCCGACTGCGAAAGTTCGACGACACGTTCCTGTATGTCGCGCGTCC
GCTCGACCCGATCGTGGTGGAGCGGCTCAAGCAGACCGAGCTGTCCGCCGCCGAGTACACCCAGCTCGAGTCGCGCCGCC
TGGGCATCCAGGTGGCGCTGGCGTTGATGTTCGCGGTCATCGCGCTCACTATCCTGATGGCGTCGGTACTAATCGGCCTG
AACTTCGCGAACTGGCTTGTGGCGCCGATCCGGCAGCTGATGAACGCCGCGCATACGGTCGCGACCGGCGACCTCCACGT
CCAGGTGCCGGTGCATCGCTCGGAGGGCGATCTCGCCCAGCTCGGCCAGACCTTCAACAAGATGACGCAGGAGCTGCGCA
CTCAGCGCGACGAGCTGGTGAGCGCCAGCGACCTAATCGACAGCCGGCGCCGCTTCATCGAGGCCGTGCTGTCGTCGGCC
TCGGCCGGCATCATCGGCGTCGATGCGTCGGGCAGCGTCGGCATCCTCAACCGTTCGGCCGAGAAACTGATCGGCCATGC
CGAGCAGGAGGTGCTCGATCATCCGCTGTCCGAGGTGCTGCCCGAGCTCGACGACATGATGAAGACGGCGCGCGAGGGCA
AGCAGCGGCTGGTGCAGGGACAGATCACGATCCAGCGCGACGGCCATGAGCGCAATCTGTCGGTGCGCGTCACCGCCGAG
CAGACCAACCAGGCGCGCGACAGCTACATCATCACGCTCGACGACATCACTGAATTGGTGTCGGCGCAGCGCACCTCGGC
ATGGGGCGACGTCGCGCGGCGCATCGCACACGAGATCAAGAATCCGCTCACGCCAATTCAGCTGTCCGCGGAGCGCATCC
GCCGCAAATTCGGCAAGGTCATCACCGAGGACAAGGCCGTATTTGAGCAATGTACCGAGACGATCGTGCGGCAGGTCGAC
GACATCAGGCGAATGGTCGACGAGTTCTCGCGATTCGCGCGGATGCCGAAGCCGGTGATGGAAGGCGAGGATGTCGCCGA
CGCGGTGCGCCAGGCCGTGTTCCTGATGAAGGTCGCCCATCCCGAGATCGACATCGAGACCGACATCAAGCAGGACCCGT
TGCGCGCGCAGTTCGACCGCCGTCTGATCTCGCAGGCGCTGACCAACATCATCAAGAACGCCACCGAGGCGATCGAGGTG
GTCCCGCAAGAGGAGCTCGGCAAGGGCCGCATCGATGTCGTCGCCGCGCGCGAAGGCGATGACGTGCTGATCGACGTGAT
CGACAACGGCATCGGCCTGCCCAAAGTGGCTCGGCAGCGGCTGCTCGAGCCCTATGTCACGACGCGCGCCAAGGGCACCG
GCCTCGGGCTCGCGATCGTCGGCCGTGTGCTTGAGGACCATGGCGGCAAGCTCGAGCTCAAGGACGCCGCCGATTTCCGC
GCCGGACAGCGCGGCGCCTGGATGCGGCTGCGTTTCGCGGTGTCCGGCCAGGCCGCAAAACCCGAGGTGAAGGAGCAGAC
GGCTGCTCCCGACAATTCGCGACAGGCGGAGACCGGCGGGGAAACCGCCGGCACAGCTCAAGCGACCAACGATCAACCAA
AGATTCAAGCCGCAACCAGCGGCTGA

Upstream 100 bases:

>100_bases
TCCGCGCCGTGGATTTGTCGCAATTTGGCAACAGCGTGGTAGGAATGCATCAGTCCGATTCCTTTGGACGTGCCGCGTTC
ACATCACACCCCTTGCCGGA

Downstream 100 bases:

>100_bases
CGAGACAGGCGTGACCCATGGCGAGTGATATTCTCATTGTCGACGACGAAGCCGATATCCGGGAGCTGGTTGCCGGCATC
CTGGACGATGAAGGCTTCAC

Product: nitrogen regulation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MTSAEASATPFDPSSADARRWTWRTWLAPVAVGLALLSAFLTFIVLVGLSPIEPTAEVVNTFYLIDIGTILVLVGIIVRE
VWQMIQARRRGRAAARLHVQIVSLFSVIAVLPAVMVAMVANVVIDRGLDRLFSGPTREVIQNSRIIASAYMQAHAQLIYG
DIVGMANDVSYARLLFDQDRQSFLQMLVADAATRNLPGAMIIDKNTDPILSAETGGIPLTYAPPPPDMLKNVGEDKPEIA
VLPDQNNVAAVIRLRKFDDTFLYVARPLDPIVVERLKQTELSAAEYTQLESRRLGIQVALALMFAVIALTILMASVLIGL
NFANWLVAPIRQLMNAAHTVATGDLHVQVPVHRSEGDLAQLGQTFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSA
SAGIIGVDASGSVGILNRSAEKLIGHAEQEVLDHPLSEVLPELDDMMKTAREGKQRLVQGQITIQRDGHERNLSVRVTAE
QTNQARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVITEDKAVFEQCTETIVRQVD
DIRRMVDEFSRFARMPKPVMEGEDVADAVRQAVFLMKVAHPEIDIETDIKQDPLRAQFDRRLISQALTNIIKNATEAIEV
VPQEELGKGRIDVVAAREGDDVLIDVIDNGIGLPKVARQRLLEPYVTTRAKGTGLGLAIVGRVLEDHGGKLELKDAADFR
AGQRGAWMRLRFAVSGQAAKPEVKEQTAAPDNSRQAETGGETAGTAQATNDQPKIQAATSG

Sequences:

>Translated_781_residues
MTSAEASATPFDPSSADARRWTWRTWLAPVAVGLALLSAFLTFIVLVGLSPIEPTAEVVNTFYLIDIGTILVLVGIIVRE
VWQMIQARRRGRAAARLHVQIVSLFSVIAVLPAVMVAMVANVVIDRGLDRLFSGPTREVIQNSRIIASAYMQAHAQLIYG
DIVGMANDVSYARLLFDQDRQSFLQMLVADAATRNLPGAMIIDKNTDPILSAETGGIPLTYAPPPPDMLKNVGEDKPEIA
VLPDQNNVAAVIRLRKFDDTFLYVARPLDPIVVERLKQTELSAAEYTQLESRRLGIQVALALMFAVIALTILMASVLIGL
NFANWLVAPIRQLMNAAHTVATGDLHVQVPVHRSEGDLAQLGQTFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSA
SAGIIGVDASGSVGILNRSAEKLIGHAEQEVLDHPLSEVLPELDDMMKTAREGKQRLVQGQITIQRDGHERNLSVRVTAE
QTNQARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVITEDKAVFEQCTETIVRQVD
DIRRMVDEFSRFARMPKPVMEGEDVADAVRQAVFLMKVAHPEIDIETDIKQDPLRAQFDRRLISQALTNIIKNATEAIEV
VPQEELGKGRIDVVAAREGDDVLIDVIDNGIGLPKVARQRLLEPYVTTRAKGTGLGLAIVGRVLEDHGGKLELKDAADFR
AGQRGAWMRLRFAVSGQAAKPEVKEQTAAPDNSRQAETGGETAGTAQATNDQPKIQAATSG
>Mature_780_residues
TSAEASATPFDPSSADARRWTWRTWLAPVAVGLALLSAFLTFIVLVGLSPIEPTAEVVNTFYLIDIGTILVLVGIIVREV
WQMIQARRRGRAAARLHVQIVSLFSVIAVLPAVMVAMVANVVIDRGLDRLFSGPTREVIQNSRIIASAYMQAHAQLIYGD
IVGMANDVSYARLLFDQDRQSFLQMLVADAATRNLPGAMIIDKNTDPILSAETGGIPLTYAPPPPDMLKNVGEDKPEIAV
LPDQNNVAAVIRLRKFDDTFLYVARPLDPIVVERLKQTELSAAEYTQLESRRLGIQVALALMFAVIALTILMASVLIGLN
FANWLVAPIRQLMNAAHTVATGDLHVQVPVHRSEGDLAQLGQTFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSAS
AGIIGVDASGSVGILNRSAEKLIGHAEQEVLDHPLSEVLPELDDMMKTAREGKQRLVQGQITIQRDGHERNLSVRVTAEQ
TNQARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKVITEDKAVFEQCTETIVRQVDD
IRRMVDEFSRFARMPKPVMEGEDVADAVRQAVFLMKVAHPEIDIETDIKQDPLRAQFDRRLISQALTNIIKNATEAIEVV
PQEELGKGRIDVVAAREGDDVLIDVIDNGIGLPKVARQRLLEPYVTTRAKGTGLGLAIVGRVLEDHGGKLELKDAADFRA
GQRGAWMRLRFAVSGQAAKPEVKEQTAAPDNSRQAETGGETAGTAQATNDQPKIQAATSG

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=384, Percent_Identity=24.4791666666667, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1790300, Length=342, Percent_Identity=27.1929824561404, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85696; Mature: 85564

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAEASATPFDPSSADARRWTWRTWLAPVAVGLALLSAFLTFIVLVGLSPIEPTAEVVN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TFYLIDIGTILVLVGIIVREVWQMIQARRRGRAAARLHVQIVSLFSVIAVLPAVMVAMVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVIDRGLDRLFSGPTREVIQNSRIIASAYMQAHAQLIYGDIVGMANDVSYARLLFDQDR
HHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSFLQMLVADAATRNLPGAMIIDKNTDPILSAETGGIPLTYAPPPPDMLKNVGEDKPEIA
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCEEEEECCCCHHHHHHCCCCCCCEE
VLPDQNNVAAVIRLRKFDDTFLYVARPLDPIVVERLKQTELSAAEYTQLESRRLGIQVAL
EECCCCCEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMFAVIALTILMASVLIGLNFANWLVAPIRQLMNAAHTVATGDLHVQVPVHRSEGDLAQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHH
LGQTFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSASAGIIGVDASGSVGILNRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
EKLIGHAEQEVLDHPLSEVLPELDDMMKTAREGKQRLVQGQITIQRDGHERNLSVRVTAE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEEEH
QTNQARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKV
HCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ITEDKAVFEQCTETIVRQVDDIRRMVDEFSRFARMPKPVMEGEDVADAVRQAVFLMKVAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
PEIDIETDIKQDPLRAQFDRRLISQALTNIIKNATEAIEVVPQEELGKGRIDVVAAREGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCC
DVLIDVIDNGIGLPKVARQRLLEPYVTTRAKGTGLGLAIVGRVLEDHGGKLELKDAADFR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCHHCC
AGQRGAWMRLRFAVSGQAAKPEVKEQTAAPDNSRQAETGGETAGTAQATNDQPKIQAATS
CCCCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
G
C
>Mature Secondary Structure 
TSAEASATPFDPSSADARRWTWRTWLAPVAVGLALLSAFLTFIVLVGLSPIEPTAEVVN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TFYLIDIGTILVLVGIIVREVWQMIQARRRGRAAARLHVQIVSLFSVIAVLPAVMVAMVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVIDRGLDRLFSGPTREVIQNSRIIASAYMQAHAQLIYGDIVGMANDVSYARLLFDQDR
HHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSFLQMLVADAATRNLPGAMIIDKNTDPILSAETGGIPLTYAPPPPDMLKNVGEDKPEIA
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCEEEEECCCCHHHHHHCCCCCCCEE
VLPDQNNVAAVIRLRKFDDTFLYVARPLDPIVVERLKQTELSAAEYTQLESRRLGIQVAL
EECCCCCEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMFAVIALTILMASVLIGLNFANWLVAPIRQLMNAAHTVATGDLHVQVPVHRSEGDLAQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHH
LGQTFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSASAGIIGVDASGSVGILNRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
EKLIGHAEQEVLDHPLSEVLPELDDMMKTAREGKQRLVQGQITIQRDGHERNLSVRVTAE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEEEH
QTNQARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIRRKFGKV
HCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ITEDKAVFEQCTETIVRQVDDIRRMVDEFSRFARMPKPVMEGEDVADAVRQAVFLMKVAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
PEIDIETDIKQDPLRAQFDRRLISQALTNIIKNATEAIEVVPQEELGKGRIDVVAAREGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCC
DVLIDVIDNGIGLPKVARQRLLEPYVTTRAKGTGLGLAIVGRVLEDHGGKLELKDAADFR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCHHCC
AGQRGAWMRLRFAVSGQAAKPEVKEQTAAPDNSRQAETGGETAGTAQATNDQPKIQAATS
CCCCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]