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The map label for this gene is lrp [H]

Identifier: 146340747

GI number: 146340747

Start: 3973059

End: 3973547

Strand: Reverse

Name: lrp [H]

Synonym: BRADO3802

Alternate gene names: 146340747

Gene position: 3973547-3973059 (Counterclockwise)

Preceding gene: 146340750

Following gene: 146340746

Centisome position: 53.29

GC content: 62.37

Gene sequence:

>489_bases
ATGGCGCCTTCAACGAAAGAAACTTCCGACGCGGATCTCGACCGTGTCGATCGCCGCATTCTGCAGCTGCTGCAGAAGGA
CGGCCGGATGAGCAATGCCGAGCTCGCCGCTGCCGTTCATGTCAGCCCGGCGACCTGCCATCGCCGCACCCAGCGCCTGT
TCGAGGACGGCTATATCAAGAGCGTGCGTGCGCAGATCGCGCCGGAGAAGGTCGAGCGCAGCGCGCTCGTGCTGGTCGGC
GTCGTCCTCGACCGCTCGACGCCGGAGAGCTTCCGCACCTTCGAAGCCGCGATCCGCAAGCTGAAATTCGTGCTCGATTG
CCATCTCGTCGCCGGCGACTTCGACTTCTTTCTCAAGATCCGCGTCCGCGACATGCAGGATTTCAATCGCATGCATGGCG
ACCAGCTGATCTCGCTGCCCAGCGTACGGCAGACCCGCACGTTCTTCGTGATGAAGGAGGTGGTCGACAATGCGCCGCTG
GATTTTTGA

Upstream 100 bases:

>100_bases
TCATCTTACGTAAAAGCTCCGGAAAGGTGCTCTCTTTTTCGGCGACTATTTTCATGCTTACATCCGATTATTCCTTTGAT
ACTGATGGAAACATCCGTTC

Downstream 100 bases:

>100_bases
GCCCTCGGCGGATTGAACCGGAGGTGTGCGATGCGCGACTTACCAGCGCGTGAGCTCGCTCACATCAGCAACCGACATCG
CGGAGATCCTGATGAAGAGG

Product: AsnC/Lrp family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAPSTKETSDADLDRVDRRILQLLQKDGRMSNAELAAAVHVSPATCHRRTQRLFEDGYIKSVRAQIAPEKVERSALVLVG
VVLDRSTPESFRTFEAAIRKLKFVLDCHLVAGDFDFFLKIRVRDMQDFNRMHGDQLISLPSVRQTRTFFVMKEVVDNAPL
DF

Sequences:

>Translated_162_residues
MAPSTKETSDADLDRVDRRILQLLQKDGRMSNAELAAAVHVSPATCHRRTQRLFEDGYIKSVRAQIAPEKVERSALVLVG
VVLDRSTPESFRTFEAAIRKLKFVLDCHLVAGDFDFFLKIRVRDMQDFNRMHGDQLISLPSVRQTRTFFVMKEVVDNAPL
DF
>Mature_161_residues
APSTKETSDADLDRVDRRILQLLQKDGRMSNAELAAAVHVSPATCHRRTQRLFEDGYIKSVRAQIAPEKVERSALVLVGV
VLDRSTPESFRTFEAAIRKLKFVLDCHLVAGDFDFFLKIRVRDMQDFNRMHGDQLISLPSVRQTRTFFVMKEVVDNAPLD
F

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=45.3333333333333, Blast_Score=143, Evalue=5e-36,
Organism=Escherichia coli, GI87081742, Length=142, Percent_Identity=27.4647887323944, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=24.4755244755245, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18509; Mature: 18377

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSTKETSDADLDRVDRRILQLLQKDGRMSNAELAAAVHVSPATCHRRTQRLFEDGYIK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHH
SVRAQIAPEKVERSALVLVGVVLDRSTPESFRTFEAAIRKLKFVLDCHLVAGDFDFFLKI
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEE
RVRDMQDFNRMHGDQLISLPSVRQTRTFFVMKEVVDNAPLDF
EEHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
APSTKETSDADLDRVDRRILQLLQKDGRMSNAELAAAVHVSPATCHRRTQRLFEDGYIK
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHH
SVRAQIAPEKVERSALVLVGVVLDRSTPESFRTFEAAIRKLKFVLDCHLVAGDFDFFLKI
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEE
RVRDMQDFNRMHGDQLISLPSVRQTRTFFVMKEVVDNAPLDF
EEHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]