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The map label for this gene is recG [H]

Identifier: 146340717

GI number: 146340717

Start: 3936133

End: 3938235

Strand: Reverse

Name: recG [H]

Synonym: BRADO3769

Alternate gene names: 146340717

Gene position: 3938235-3936133 (Counterclockwise)

Preceding gene: 146340720

Following gene: 146340714

Centisome position: 52.82

GC content: 68.24

Gene sequence:

>2103_bases
ATGCGCCCTGCCATCCTCAACCCGCTGTTTGCGCCGGTCACGACCCTCTCGGGTGTCGGGCCGAAGCAGGACAAGCTGCT
GCGCTACCTGCTGAGCTGCAGCGAGACGCCGCGGCTCGTCGACCTGCTGCTGCATCTGCCGGCCAGCGTCATCGACCGCC
GGAACCGGCCCAAGGTCCGCGACGTCGAGGTCGGCACCGTGGTGACCCTGGAGGTGACGGTCGATCGCCATCGTCCGTCG
CGTAACGCGCGCGCCCCTTATCTGGTTTACGCCAGCGACGACACCGGCGACGTCGTGCTGACGTTTTTTCGGCCCAAGGG
CGACTACATCGAGAAGATGCTGCCGGTCGGCGCCAAGCGCTACGTCTCCGGCACCGTGCAGATGTACGACGGTATCCCGC
AGATCGTGCACCCCGACCGCATCCTCGATGAAGCCGGCTTCGCCAAACTGTCAGGAATCGACCCGGTCTATCCGCTCACC
GAAGGCCTCGCGCTCGGCTCGCTGCGGCGGGCGATCGCGGCGGCGCTGACCAAGCTGCCGGAGCTGCCGGAATGGATCAG
CCCGGAGGTGCTGAGCCGCTGCAATTTCCCGTCGCTGAGGGAGGCGCTGACGCGGGTGCACGTCCCGCAAGAGCTGACGG
ATATACTGCCCGAAAATCCGTTCTGGTCGCGCCTCGCCTTTGACGAGCTGCTTGCCGGCCAATTGGCCCTGGCGCTGGTG
CGCGCGCAATTGCGCCGTCCCGCGGGCAACCGCCACGCCGGCGACGGCCGCCTGCGCCGCAGGATCATCGATGCCCTTCC
CTATGCGCTGACCAACTCGCAGGCCCAGGCGATCGAGGCGATCGCCGCCGATCTGGAAAAGCCCGTGCGCATGCTCCGGC
TGCTGCAGGGCGACGTCGGTTCGGGCAAGACGGTGGTCGCGCTGCTCGCCGCGGCGGCCGTGGCCGAGGCCGGCAAGCAG
GCCGCGCTGATGGCGCCGACCGAAATCCTGGCGCGACAGCATGCCAAGACCATCGCGCCGCTCGCCGAGCGCGCGGGCAT
GAGCGTCGCCATTCTCACCGGCCGCGAGAAAGTTAAGGAGCGCCGCGACATCCTTGCCCGCCTGGAGGCCGGCGAGATCG
ACGTCCTGATTGGCACCCATGCGCTGATCCAAGACGACGTCATGTTCAAATCGCTGGCGCTCGCCATCGTCGACGAGCAG
CATCGCTTCGGGGTGCGCGAGAGGCTGGCGCTGACCTCCAAGGGCGAGGCCGTCGACGTGCTCGTGCTGTCCGCGACGCC
GATCCCGCGCACGCTGGTCCTCACCTATTTCGGCGACATGGACATTTCCGAGCTACGCGAGAAGCCGGCCGGCCGGCAGC
CGATCGACACCCGCGCGGTGGCTGACACCCGGCGCACCGAGGTCATCGACGCCGTCGGCCGCGCGCTCGACGCCGGCAAG
CTGGTGTACTGGATCTGCCCGCTGGTCGAGGAGTCCGAGGCCGAAGGCATCGATCATCTCACCAACGCCACCGACCGCTA
CGAAAGCCTGCGCGAGCGCTTCGGCGAGCGTGTCGGCCTCGTCCACGGCAAGATGAAGGGCAGCGAGAAGGACGACGTCA
TGAACCGCTTCGCGGCGCATGAACTGCGGCTGCTCGTTGCCACGACGGTCGTCGAGGTCGGAGTCGACGTGCCCGCCGCG
AGCATCATGGTGATCGAGAATGCCGAGCGCTTCGGCCTCGCCCAGTTGCATCAGCTGCGCGGCCGCATCGGCCGCGGCTC
GGAAGCCTCGACCTGCATCCTGCTCTATCACGAGCCGCTCGGCCAGATGTCGAAGGCGCGGCTCGCCGTCATCCGCGAGA
CCACCGACGGCTTCCGCATCGCCGAGGAGGATCTCAAGCTGCGCGGCGAAGGCGACGTGCTGGGCATCCGCCAGAGCGGC
CTGCCCGGCTACCGCATCGCCCGGCCCGAGGTGCATGCGCAGCTGATCACGCAGGCCCGCGACGAGGCGTTACGGATCCT
GAAGGACGATCCCAAGCTGAAGGGACCGCGCAGCGATGCGCTGCGCTGTCTGCTGTATCTCTACGAACGCGACGAGGCGA
TCCCGCTGCTCACGGCGGGGTGA

Upstream 100 bases:

>100_bases
GAACCGGCATGTCGGGCCGCCTCAAACCGGGGAAAAAAGAGGTGGATGTCTCGACGATCGCGGCTATTCCGGCCCGCAAA
GCGAATTAAGTGTTCGGTCC

Downstream 100 bases:

>100_bases
TTGAGGCGGTGCATCAACAAACTCCGCTGTCGTCCCGGCCTCCGAGCCCGGACCCATACCCCCAGGGAGCAGTTTGAGGC
AGGCTGGCGATTGGCTCTTT

Product: DNA helicase, ATP-dependent resolution of Holliday junctions, branch migration

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MRPAILNPLFAPVTTLSGVGPKQDKLLRYLLSCSETPRLVDLLLHLPASVIDRRNRPKVRDVEVGTVVTLEVTVDRHRPS
RNARAPYLVYASDDTGDVVLTFFRPKGDYIEKMLPVGAKRYVSGTVQMYDGIPQIVHPDRILDEAGFAKLSGIDPVYPLT
EGLALGSLRRAIAAALTKLPELPEWISPEVLSRCNFPSLREALTRVHVPQELTDILPENPFWSRLAFDELLAGQLALALV
RAQLRRPAGNRHAGDGRLRRRIIDALPYALTNSQAQAIEAIAADLEKPVRMLRLLQGDVGSGKTVVALLAAAAVAEAGKQ
AALMAPTEILARQHAKTIAPLAERAGMSVAILTGREKVKERRDILARLEAGEIDVLIGTHALIQDDVMFKSLALAIVDEQ
HRFGVRERLALTSKGEAVDVLVLSATPIPRTLVLTYFGDMDISELREKPAGRQPIDTRAVADTRRTEVIDAVGRALDAGK
LVYWICPLVEESEAEGIDHLTNATDRYESLRERFGERVGLVHGKMKGSEKDDVMNRFAAHELRLLVATTVVEVGVDVPAA
SIMVIENAERFGLAQLHQLRGRIGRGSEASTCILLYHEPLGQMSKARLAVIRETTDGFRIAEEDLKLRGEGDVLGIRQSG
LPGYRIARPEVHAQLITQARDEALRILKDDPKLKGPRSDALRCLLYLYERDEAIPLLTAG

Sequences:

>Translated_700_residues
MRPAILNPLFAPVTTLSGVGPKQDKLLRYLLSCSETPRLVDLLLHLPASVIDRRNRPKVRDVEVGTVVTLEVTVDRHRPS
RNARAPYLVYASDDTGDVVLTFFRPKGDYIEKMLPVGAKRYVSGTVQMYDGIPQIVHPDRILDEAGFAKLSGIDPVYPLT
EGLALGSLRRAIAAALTKLPELPEWISPEVLSRCNFPSLREALTRVHVPQELTDILPENPFWSRLAFDELLAGQLALALV
RAQLRRPAGNRHAGDGRLRRRIIDALPYALTNSQAQAIEAIAADLEKPVRMLRLLQGDVGSGKTVVALLAAAAVAEAGKQ
AALMAPTEILARQHAKTIAPLAERAGMSVAILTGREKVKERRDILARLEAGEIDVLIGTHALIQDDVMFKSLALAIVDEQ
HRFGVRERLALTSKGEAVDVLVLSATPIPRTLVLTYFGDMDISELREKPAGRQPIDTRAVADTRRTEVIDAVGRALDAGK
LVYWICPLVEESEAEGIDHLTNATDRYESLRERFGERVGLVHGKMKGSEKDDVMNRFAAHELRLLVATTVVEVGVDVPAA
SIMVIENAERFGLAQLHQLRGRIGRGSEASTCILLYHEPLGQMSKARLAVIRETTDGFRIAEEDLKLRGEGDVLGIRQSG
LPGYRIARPEVHAQLITQARDEALRILKDDPKLKGPRSDALRCLLYLYERDEAIPLLTAG
>Mature_700_residues
MRPAILNPLFAPVTTLSGVGPKQDKLLRYLLSCSETPRLVDLLLHLPASVIDRRNRPKVRDVEVGTVVTLEVTVDRHRPS
RNARAPYLVYASDDTGDVVLTFFRPKGDYIEKMLPVGAKRYVSGTVQMYDGIPQIVHPDRILDEAGFAKLSGIDPVYPLT
EGLALGSLRRAIAAALTKLPELPEWISPEVLSRCNFPSLREALTRVHVPQELTDILPENPFWSRLAFDELLAGQLALALV
RAQLRRPAGNRHAGDGRLRRRIIDALPYALTNSQAQAIEAIAADLEKPVRMLRLLQGDVGSGKTVVALLAAAAVAEAGKQ
AALMAPTEILARQHAKTIAPLAERAGMSVAILTGREKVKERRDILARLEAGEIDVLIGTHALIQDDVMFKSLALAIVDEQ
HRFGVRERLALTSKGEAVDVLVLSATPIPRTLVLTYFGDMDISELREKPAGRQPIDTRAVADTRRTEVIDAVGRALDAGK
LVYWICPLVEESEAEGIDHLTNATDRYESLRERFGERVGLVHGKMKGSEKDDVMNRFAAHELRLLVATTVVEVGVDVPAA
SIMVIENAERFGLAQLHQLRGRIGRGSEASTCILLYHEPLGQMSKARLAVIRETTDGFRIAEEDLKLRGEGDVLGIRQSG
LPGYRIARPEVHAQLITQARDEALRILKDDPKLKGPRSDALRCLLYLYERDEAIPLLTAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=651, Percent_Identity=41.0138248847926, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787357, Length=385, Percent_Identity=40, Blast_Score=251, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77023; Mature: 77023

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAILNPLFAPVTTLSGVGPKQDKLLRYLLSCSETPRLVDLLLHLPASVIDRRNRPKVR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCCCE
DVEVGTVVTLEVTVDRHRPSRNARAPYLVYASDDTGDVVLTFFRPKGDYIEKMLPVGAKR
EEECCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHCCCHHH
YVSGTVQMYDGIPQIVHPDRILDEAGFAKLSGIDPVYPLTEGLALGSLRRAIAAALTKLP
HHHHHHHHHCCCCCCCCCHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
ELPEWISPEVLSRCNFPSLREALTRVHVPQELTDILPENPFWSRLAFDELLAGQLALALV
CCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RAQLRRPAGNRHAGDGRLRRRIIDALPYALTNSQAQAIEAIAADLEKPVRMLRLLQGDVG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGKTVVALLAAAAVAEAGKQAALMAPTEILARQHAKTIAPLAERAGMSVAILTGREKVKE
CCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
RRDILARLEAGEIDVLIGTHALIQDDVMFKSLALAIVDEQHRFGVRERLALTSKGEAVDV
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHCCCCCEEEE
LVLSATPIPRTLVLTYFGDMDISELREKPAGRQPIDTRAVADTRRTEVIDAVGRALDAGK
EEEECCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LVYWICPLVEESEAEGIDHLTNATDRYESLRERFGERVGLVHGKMKGSEKDDVMNRFAAH
EEEEEECHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
ELRLLVATTVVEVGVDVPAASIMVIENAERFGLAQLHQLRGRIGRGSEASTCILLYHEPL
HHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GQMSKARLAVIRETTDGFRIAEEDLKLRGEGDVLGIRQSGLPGYRIARPEVHAQLITQAR
CHHHHHHEEHEEECCCCCEEEHHHHEECCCCCEEEEECCCCCCCEECCHHHHHHHHHHHH
DEALRILKDDPKLKGPRSDALRCLLYLYERDEAIPLLTAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MRPAILNPLFAPVTTLSGVGPKQDKLLRYLLSCSETPRLVDLLLHLPASVIDRRNRPKVR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCCCE
DVEVGTVVTLEVTVDRHRPSRNARAPYLVYASDDTGDVVLTFFRPKGDYIEKMLPVGAKR
EEECCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHCCCHHH
YVSGTVQMYDGIPQIVHPDRILDEAGFAKLSGIDPVYPLTEGLALGSLRRAIAAALTKLP
HHHHHHHHHCCCCCCCCCHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
ELPEWISPEVLSRCNFPSLREALTRVHVPQELTDILPENPFWSRLAFDELLAGQLALALV
CCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RAQLRRPAGNRHAGDGRLRRRIIDALPYALTNSQAQAIEAIAADLEKPVRMLRLLQGDVG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGKTVVALLAAAAVAEAGKQAALMAPTEILARQHAKTIAPLAERAGMSVAILTGREKVKE
CCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
RRDILARLEAGEIDVLIGTHALIQDDVMFKSLALAIVDEQHRFGVRERLALTSKGEAVDV
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHCCCCCEEEE
LVLSATPIPRTLVLTYFGDMDISELREKPAGRQPIDTRAVADTRRTEVIDAVGRALDAGK
EEEECCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LVYWICPLVEESEAEGIDHLTNATDRYESLRERFGERVGLVHGKMKGSEKDDVMNRFAAH
EEEEEECHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
ELRLLVATTVVEVGVDVPAASIMVIENAERFGLAQLHQLRGRIGRGSEASTCILLYHEPL
HHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GQMSKARLAVIRETTDGFRIAEEDLKLRGEGDVLGIRQSGLPGYRIARPEVHAQLITQAR
CHHHHHHEEHEEECCCCCEEEHHHHEECCCCCEEEEECCCCCCCEECCHHHHHHHHHHHH
DEALRILKDDPKLKGPRSDALRCLLYLYERDEAIPLLTAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]