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The map label for this gene is glpX [H]

Identifier: 146340530

GI number: 146340530

Start: 3766319

End: 3767320

Strand: Direct

Name: glpX [H]

Synonym: BRADO3573

Alternate gene names: 146340530

Gene position: 3766319-3767320 (Clockwise)

Preceding gene: 146340529

Following gene: 146340531

Centisome position: 50.51

GC content: 68.26

Gene sequence:

>1002_bases
ATGTCGACGCAGATTTCCGTCCCGCAACAATTGCTGCTCGAGCGCATCCTCACCTTGGAGCTGGTGCGCGTGACCGAGCG
GGCGGCGGTGTCGGCGGCGCGTCTGCGCGGCCATGGTCAGGAGAAGCCGGCCGACCAGGCGGCGGTCGACGCGATGCGCC
GCGAACTCAACAAGCTGCCGATCGAGGGCACGATCGTGATCGGCGAGGGCGAGCGCGACGAGGCGCCGATGCTCTACATC
GGCGAGAAGGTCGGCCTCAACGCCGGTCCCCGCGTGGACATCGCTGTTGACCCGCTTGAAGGCACCACCCTGTGCGCCAA
GAACATGCCCGGTTCGATCGCCACCATGGCGATGGCGGACGGCGGCACCCTGCTGCACGCGCCGGACGTCTACATGCAGA
AGATCGCCGTCGGTCCCGGCTACCAGAAGGGCGTGGTCGATCTCGATGCGACGCCCGCTGACAATGTTCGCCGTCTGGCC
AAGGCCAAGGGCGTGGATACCTCGGCCATCACCGTGCTGGTTCTGGACCGTCCCCGTCACGCCGACATCATTCACGGCGT
GCGCTCGACCGGCGCCGCCGTGCGCCTGATCACCGACGGTGACGTCGCCGGCGTGATCCATTGCGCCGATCCCGACAACA
CCGGCGTCGACATGTATCTCGGCACCGGCGGCGCGCCCGAGGGCGTGCTGGCCGCGGTGGCCCTGCGCTGCATCGGCGGC
CAGATGCAGTGCCGCCTGATCCTCGACACCGAGGAGAAGCGCGAGCGCGCCCACAAGATGGGCGTCGGCGATCCCAAGAT
GATCTACGGCATCGAGGACATGGCCCGCGGCGACTGCTTGTTCGCGGCCACCGGCGTCACCACCGGCTCGCTGCTCTCCG
GCGTCAAGTTCCGCAAGGACGGGGTGATCGAGACCGAGACCGTCGTGATGCGCTCGGTCACCGGCACCGTGCGCTACATC
CGCGCCGAGCACCGCCAGCTGGAGAAGTTCCACCTCGACTGA

Upstream 100 bases:

>100_bases
CCGGGCCGGCCCGCTGAACCGTGAGCCGCCCCCGATGGCGGCTGCCGGCTGGTAGAATTTGATGGCGGAGATCCGCCTTG
ACGTCTTGAGGAGTTGACCG

Downstream 100 bases:

>100_bases
CGGCGGAGCGTCGCGATGTCCGATCTCTCGATGGTCAAGGCGCTGGTGTTCGACGTGTTCGGCACCGTCGTCGACTGGCG
CACCAGTCTGATCAACGATT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSTQISVPQQLLLERILTLELVRVTERAAVSAARLRGHGQEKPADQAAVDAMRRELNKLPIEGTIVIGEGERDEAPMLYI
GEKVGLNAGPRVDIAVDPLEGTTLCAKNMPGSIATMAMADGGTLLHAPDVYMQKIAVGPGYQKGVVDLDATPADNVRRLA
KAKGVDTSAITVLVLDRPRHADIIHGVRSTGAAVRLITDGDVAGVIHCADPDNTGVDMYLGTGGAPEGVLAAVALRCIGG
QMQCRLILDTEEKRERAHKMGVGDPKMIYGIEDMARGDCLFAATGVTTGSLLSGVKFRKDGVIETETVVMRSVTGTVRYI
RAEHRQLEKFHLD

Sequences:

>Translated_333_residues
MSTQISVPQQLLLERILTLELVRVTERAAVSAARLRGHGQEKPADQAAVDAMRRELNKLPIEGTIVIGEGERDEAPMLYI
GEKVGLNAGPRVDIAVDPLEGTTLCAKNMPGSIATMAMADGGTLLHAPDVYMQKIAVGPGYQKGVVDLDATPADNVRRLA
KAKGVDTSAITVLVLDRPRHADIIHGVRSTGAAVRLITDGDVAGVIHCADPDNTGVDMYLGTGGAPEGVLAAVALRCIGG
QMQCRLILDTEEKRERAHKMGVGDPKMIYGIEDMARGDCLFAATGVTTGSLLSGVKFRKDGVIETETVVMRSVTGTVRYI
RAEHRQLEKFHLD
>Mature_332_residues
STQISVPQQLLLERILTLELVRVTERAAVSAARLRGHGQEKPADQAAVDAMRRELNKLPIEGTIVIGEGERDEAPMLYIG
EKVGLNAGPRVDIAVDPLEGTTLCAKNMPGSIATMAMADGGTLLHAPDVYMQKIAVGPGYQKGVVDLDATPADNVRRLAK
AKGVDTSAITVLVLDRPRHADIIHGVRSTGAAVRLITDGDVAGVIHCADPDNTGVDMYLGTGGAPEGVLAAVALRCIGGQ
MQCRLILDTEEKRERAHKMGVGDPKMIYGIEDMARGDCLFAATGVTTGSLLSGVKFRKDGVIETETVVMRSVTGTVRYIR
AEHRQLEKFHLD

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=326, Percent_Identity=45.7055214723926, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1789298, Length=322, Percent_Identity=40.6832298136646, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35565; Mature: 35433

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQISVPQQLLLERILTLELVRVTERAAVSAARLRGHGQEKPADQAAVDAMRRELNKLP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
IEGTIVIGEGERDEAPMLYIGEKVGLNAGPRVDIAVDPLEGTTLCAKNMPGSIATMAMAD
CCEEEEEECCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEEEC
GGTLLHAPDVYMQKIAVGPGYQKGVVDLDATPADNVRRLAKAKGVDTSAITVLVLDRPRH
CCEEEECCHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCC
ADIIHGVRSTGAAVRLITDGDVAGVIHCADPDNTGVDMYLGTGGAPEGVLAAVALRCIGG
HHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
QMQCRLILDTEEKRERAHKMGVGDPKMIYGIEDMARGDCLFAATGVTTGSLLSGVKFRKD
CEEEEEEECCHHHHHHHHHCCCCCCCEEEEHHHHCCCCEEEEECCCCHHHHHHCCEECCC
GVIETETVVMRSVTGTVRYIRAEHRQLEKFHLD
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STQISVPQQLLLERILTLELVRVTERAAVSAARLRGHGQEKPADQAAVDAMRRELNKLP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
IEGTIVIGEGERDEAPMLYIGEKVGLNAGPRVDIAVDPLEGTTLCAKNMPGSIATMAMAD
CCEEEEEECCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEEEC
GGTLLHAPDVYMQKIAVGPGYQKGVVDLDATPADNVRRLAKAKGVDTSAITVLVLDRPRH
CCEEEECCHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCC
ADIIHGVRSTGAAVRLITDGDVAGVIHCADPDNTGVDMYLGTGGAPEGVLAAVALRCIGG
HHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
QMQCRLILDTEEKRERAHKMGVGDPKMIYGIEDMARGDCLFAATGVTTGSLLSGVKFRKD
CEEEEEEECCHHHHHHHHHCCCCCCCEEEEHHHHCCCCEEEEECCCCHHHHHHCCEECCC
GVIETETVVMRSVTGTVRYIRAEHRQLEKFHLD
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]