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The map label for this gene is yheS [H]

Identifier: 146340308

GI number: 146340308

Start: 3528523

End: 3530391

Strand: Reverse

Name: yheS [H]

Synonym: BRADO3331

Alternate gene names: 146340308

Gene position: 3530391-3528523 (Counterclockwise)

Preceding gene: 146340309

Following gene: 146340304

Centisome position: 47.35

GC content: 67.09

Gene sequence:

>1869_bases
ATGCTTTCCATCACCGACATCTCCATCCGCCTCGCCGGACGGCTTCTGATCGACCAGAGCTCGGTGCAGATCCCGCCCGG
CGCGCGGGTCGGCCTGGTCGGCCGTAACGGCACCGGCAAGTCGACGCTGTTCAAGGCGATCCGCGGCGAACTGTCGCTGG
AGAACGGCAGCATCAGCCTGCCGCCACGCTGGCGCGTCGGCAGCCTGGCGCAGGAAGCCCCGAGCGGCCCCGAAAGCCTG
ATCGAGGTCGTTCTGAGGGCCGACCTCGAGCGCGACGCCCTGCTCCGCGAGGCCGAAACGGCCGAGGACCCCAACCGCAT
CGCCGAGATCCAGACCCGCCTCGTGGACATCGACGCGCATTCGGCACCGGCGCGCGCGGCCGCCATCCTCAGTGGCCTCG
GCTTCTCCGCGACCGACCAGGCGCGCGCCTGCTCGGAATTCTCCGGCGGCTGGCGCATGCGCGTGGCGCTCGCCGCGACG
CTGTTCGCCGCGCCCGACCTGCTGCTGCTCGACGAGCCAACCAACTATCTCGATCTCGAAGGCACGCTGTGGCTGGAGGA
CCATCTCGCGCATTATCCGCGCACGGTCATCGTGATCAGCCACGACCGCGATCTGCTGGAAACATCGGTCGATCAGATCC
TGCATCTCGACCGCGGCAAGCTGACGCTGTATCGCGGCTCCTATTCGTCGTTCGAGGAGCAGCGCGCGACGCGCGAGATG
CTCGACGCCAAGGCGGTCAAGCGCCAGGAGGCCGAGCGCGCCCGGCTGCAGGCCTTCGTCGAACGCTTCAAGGCCAAGGC
GTCGAAGGCGCGGCAGGCGCAATCCCGCGTCAAGATGCTCGAGCGGATGAAGCCGATCACCGCGCTGGTCACCCAGGACG
TGCACGAAATCAGCTTCCCCGCGCCCGAGAAGCTGCTGTCGCCGCCGATCATCGCGGTCGACAATGCCTCGGTCGGCTAT
GATCCCGCGCAGCCCGTGCTCAACCGCGTCACCCTGCGCATCGACAACGATGACCGCGTCGCCCTGCTCGGCGCCAACGG
CAATGGCAAGTCGACGCTGGTCAAGCTGCTCGCCGGCCGGCTCGCGCCGTTCTCCGGCAAGGTCACCCGCGCGGACAAGC
TGTCGATCGCGTATTTCGCCCAGCATCAACTCGATGAGCTCGACGAAACGGGCTCGCCCTATACGCATGTGCGCAAGCTG
ATGGGCGATGCGCCGGAATCGAAGGTGCGTGCACGCGCCGGCGCGATCGGCTTTTCCGGTAAGGCGGCCGACACGTCGGT
GAAGAGTCTCTCGGGCGGCGAGAAGGCCCGGCTGCTACTCGGCCTTGCGACCTTCTTCGGCCCGAACATGATCATCCTGG
ACGAGCCGACCAACCATCTCGATATCGACAGCCGCGCCGCGCTCGCCGAAGCAATCAACGAGTTTCCCGGCGCGGTCATC
ATGGTCTCGCACGACCGCTATCTGATCGAGGCCTGCGCCGACCGGCTGTGGGTCGTCGCCGATCGCACCGTGAAGAGCTA
TGACGGCGATCTCGACGACTACCGGCGGATGGTCCTGTCGTCGCGCAGCGGTGCAGCCGCGCGCGAGACGGACCGCCCGC
AGGTGACGGAAAAGGTCGAGCGGCCGCGCAGCGACAACAGACGCGGCGCGTTGAAGCAGAAGATCACCGCCGCGGAAGCC
GAGATTGTGCGCATCACCGACATCATCGCCAAGATCGACAGCGCGCTGTCGCTGCCCGATATCTTCACCCGCGATCCGAA
GCAGGCGGCGCAATTGTCGAAGGCCCGGGCAAACGCGGCCGATGCGCTGGCGCGGGCTGAGGAGCAATGGCTCGAAGCCA
GCACGCTCTATGATGAGGCGATCAGCTGA

Upstream 100 bases:

>100_bases
AAGCGCGACGAGCCGACAGCCCGTTTCGACTGAATCACCGGTGCGCTGAGACCGACACAAACTGGTTGCGTTTGACCGCG
CGCGCGGTGACAACGCGCGC

Downstream 100 bases:

>100_bases
CGATCTCGCATTCGTCTGTGCAAAGCGAACGCAGGATCAGGTGGCCCGCTTTTTGGCCTTGCCGGGCTTGGCCACCTTCG
GAGCAGGACCGGCATCGGGC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MLSITDISIRLAGRLLIDQSSVQIPPGARVGLVGRNGTGKSTLFKAIRGELSLENGSISLPPRWRVGSLAQEAPSGPESL
IEVVLRADLERDALLREAETAEDPNRIAEIQTRLVDIDAHSAPARAAAILSGLGFSATDQARACSEFSGGWRMRVALAAT
LFAAPDLLLLDEPTNYLDLEGTLWLEDHLAHYPRTVIVISHDRDLLETSVDQILHLDRGKLTLYRGSYSSFEEQRATREM
LDAKAVKRQEAERARLQAFVERFKAKASKARQAQSRVKMLERMKPITALVTQDVHEISFPAPEKLLSPPIIAVDNASVGY
DPAQPVLNRVTLRIDNDDRVALLGANGNGKSTLVKLLAGRLAPFSGKVTRADKLSIAYFAQHQLDELDETGSPYTHVRKL
MGDAPESKVRARAGAIGFSGKAADTSVKSLSGGEKARLLLGLATFFGPNMIILDEPTNHLDIDSRAALAEAINEFPGAVI
MVSHDRYLIEACADRLWVVADRTVKSYDGDLDDYRRMVLSSRSGAAARETDRPQVTEKVERPRSDNRRGALKQKITAAEA
EIVRITDIIAKIDSALSLPDIFTRDPKQAAQLSKARANAADALARAEEQWLEASTLYDEAIS

Sequences:

>Translated_622_residues
MLSITDISIRLAGRLLIDQSSVQIPPGARVGLVGRNGTGKSTLFKAIRGELSLENGSISLPPRWRVGSLAQEAPSGPESL
IEVVLRADLERDALLREAETAEDPNRIAEIQTRLVDIDAHSAPARAAAILSGLGFSATDQARACSEFSGGWRMRVALAAT
LFAAPDLLLLDEPTNYLDLEGTLWLEDHLAHYPRTVIVISHDRDLLETSVDQILHLDRGKLTLYRGSYSSFEEQRATREM
LDAKAVKRQEAERARLQAFVERFKAKASKARQAQSRVKMLERMKPITALVTQDVHEISFPAPEKLLSPPIIAVDNASVGY
DPAQPVLNRVTLRIDNDDRVALLGANGNGKSTLVKLLAGRLAPFSGKVTRADKLSIAYFAQHQLDELDETGSPYTHVRKL
MGDAPESKVRARAGAIGFSGKAADTSVKSLSGGEKARLLLGLATFFGPNMIILDEPTNHLDIDSRAALAEAINEFPGAVI
MVSHDRYLIEACADRLWVVADRTVKSYDGDLDDYRRMVLSSRSGAAARETDRPQVTEKVERPRSDNRRGALKQKITAAEA
EIVRITDIIAKIDSALSLPDIFTRDPKQAAQLSKARANAADALARAEEQWLEASTLYDEAIS
>Mature_622_residues
MLSITDISIRLAGRLLIDQSSVQIPPGARVGLVGRNGTGKSTLFKAIRGELSLENGSISLPPRWRVGSLAQEAPSGPESL
IEVVLRADLERDALLREAETAEDPNRIAEIQTRLVDIDAHSAPARAAAILSGLGFSATDQARACSEFSGGWRMRVALAAT
LFAAPDLLLLDEPTNYLDLEGTLWLEDHLAHYPRTVIVISHDRDLLETSVDQILHLDRGKLTLYRGSYSSFEEQRATREM
LDAKAVKRQEAERARLQAFVERFKAKASKARQAQSRVKMLERMKPITALVTQDVHEISFPAPEKLLSPPIIAVDNASVGY
DPAQPVLNRVTLRIDNDDRVALLGANGNGKSTLVKLLAGRLAPFSGKVTRADKLSIAYFAQHQLDELDETGSPYTHVRKL
MGDAPESKVRARAGAIGFSGKAADTSVKSLSGGEKARLLLGLATFFGPNMIILDEPTNHLDIDSRAALAEAINEFPGAVI
MVSHDRYLIEACADRLWVVADRTVKSYDGDLDDYRRMVLSSRSGAAARETDRPQVTEKVERPRSDNRRGALKQKITAAEA
EIVRITDIIAKIDSALSLPDIFTRDPKQAAQLSKARANAADALARAEEQWLEASTLYDEAIS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=38.3301707779886, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI10947137, Length=528, Percent_Identity=36.7424242424242, Blast_Score=330, Evalue=3e-90,
Organism=Homo sapiens, GI27881506, Length=528, Percent_Identity=36.7424242424242, Blast_Score=330, Evalue=3e-90,
Organism=Homo sapiens, GI10947135, Length=549, Percent_Identity=35.3369763205829, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI69354671, Length=549, Percent_Identity=35.3369763205829, Blast_Score=287, Evalue=3e-77,
Organism=Homo sapiens, GI171184400, Length=219, Percent_Identity=30.1369863013699, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789751, Length=626, Percent_Identity=41.85303514377, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1787041, Length=530, Percent_Identity=36.6037735849057, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1787182, Length=523, Percent_Identity=32.887189292543, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI2367384, Length=522, Percent_Identity=31.4176245210728, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1788165, Length=211, Percent_Identity=32.2274881516588, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1789891, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787758, Length=225, Percent_Identity=28, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87081791, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081834, Length=188, Percent_Identity=30.3191489361702, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789586, Length=205, Percent_Identity=26.3414634146341, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI48994943, Length=265, Percent_Identity=27.9245283018868, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI48994997, Length=249, Percent_Identity=26.1044176706827, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17553372, Length=537, Percent_Identity=37.0577281191806, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17559834, Length=558, Percent_Identity=35.3046594982079, Blast_Score=334, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17555318, Length=531, Percent_Identity=36.5348399246704, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17565586, Length=290, Percent_Identity=23.1034482758621, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=541, Percent_Identity=36.7837338262477, Blast_Score=346, Evalue=6e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=34.9146110056926, Blast_Score=317, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6325030, Length=406, Percent_Identity=29.8029556650246, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323278, Length=424, Percent_Identity=27.5943396226415, Blast_Score=133, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=436, Percent_Identity=26.605504587156, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=39.0566037735849, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24641342, Length=542, Percent_Identity=36.7158671586716, Blast_Score=337, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24642252, Length=528, Percent_Identity=36.9318181818182, Blast_Score=337, Evalue=2e-92,
Organism=Drosophila melanogaster, GI18859989, Length=528, Percent_Identity=36.9318181818182, Blast_Score=337, Evalue=2e-92,
Organism=Drosophila melanogaster, GI161077321, Length=259, Percent_Identity=28.957528957529, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 67999; Mature: 67999

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSITDISIRLAGRLLIDQSSVQIPPGARVGLVGRNGTGKSTLFKAIRGELSLENGSISL
CCEEEEEEEEEECEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEECCCCCCC
PPRWRVGSLAQEAPSGPESLIEVVLRADLERDALLREAETAEDPNRIAEIQTRLVDIDAH
CCCCCCCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHEEECCC
SAPARAAAILSGLGFSATDQARACSEFSGGWRMRVALAATLFAAPDLLLLDEPTNYLDLE
CCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHCCCEEEEECCCCEEECC
GTLWLEDHLAHYPRTVIVISHDRDLLETSVDQILHLDRGKLTLYRGSYSSFEEQRATREM
CEEEHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
LDAKAVKRQEAERARLQAFVERFKAKASKARQAQSRVKMLERMKPITALVTQDVHEISFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APEKLLSPPIIAVDNASVGYDPAQPVLNRVTLRIDNDDRVALLGANGNGKSTLVKLLAGR
CCHHHCCCCEEEECCCCCCCCCHHHHHCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
LAPFSGKVTRADKLSIAYFAQHQLDELDETGSPYTHVRKLMGDAPESKVRARAGAIGFSG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCC
KAADTSVKSLSGGEKARLLLGLATFFGPNMIILDEPTNHLDIDSRAALAEAINEFPGAVI
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
MVSHDRYLIEACADRLWVVADRTVKSYDGDLDDYRRMVLSSRSGAAARETDRPQVTEKVE
EEECCHHHHHHHHHHEEEEECCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RPRSDNRRGALKQKITAAEAEIVRITDIIAKIDSALSLPDIFTRDPKQAAQLSKARANAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHH
DALARAEEQWLEASTLYDEAIS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSITDISIRLAGRLLIDQSSVQIPPGARVGLVGRNGTGKSTLFKAIRGELSLENGSISL
CCEEEEEEEEEECEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEECCCCCCC
PPRWRVGSLAQEAPSGPESLIEVVLRADLERDALLREAETAEDPNRIAEIQTRLVDIDAH
CCCCCCCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHEEECCC
SAPARAAAILSGLGFSATDQARACSEFSGGWRMRVALAATLFAAPDLLLLDEPTNYLDLE
CCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHCCCEEEEECCCCEEECC
GTLWLEDHLAHYPRTVIVISHDRDLLETSVDQILHLDRGKLTLYRGSYSSFEEQRATREM
CEEEHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
LDAKAVKRQEAERARLQAFVERFKAKASKARQAQSRVKMLERMKPITALVTQDVHEISFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APEKLLSPPIIAVDNASVGYDPAQPVLNRVTLRIDNDDRVALLGANGNGKSTLVKLLAGR
CCHHHCCCCEEEECCCCCCCCCHHHHHCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
LAPFSGKVTRADKLSIAYFAQHQLDELDETGSPYTHVRKLMGDAPESKVRARAGAIGFSG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCC
KAADTSVKSLSGGEKARLLLGLATFFGPNMIILDEPTNHLDIDSRAALAEAINEFPGAVI
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
MVSHDRYLIEACADRLWVVADRTVKSYDGDLDDYRRMVLSSRSGAAARETDRPQVTEKVE
EEECCHHHHHHHHHHEEEEECCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RPRSDNRRGALKQKITAAEAEIVRITDIIAKIDSALSLPDIFTRDPKQAAQLSKARANAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHH
DALARAEEQWLEASTLYDEAIS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]