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The map label for this gene is ahpC [C]

Identifier: 146340217

GI number: 146340217

Start: 3437593

End: 3438252

Strand: Reverse

Name: ahpC [C]

Synonym: BRADO3235

Alternate gene names: 146340217

Gene position: 3438252-3437593 (Counterclockwise)

Preceding gene: 146340219

Following gene: 146340214

Centisome position: 46.11

GC content: 63.33

Gene sequence:

>660_bases
ATGGCTCTGCAAATCGGCTCCACCGCGCCCGACTTCGAGGCTGAGACCACCGAAGGCAAGATCAAATTCCACGACTGGAT
CGGCGACAGCTGGGCGCTGTTGTTCTCGCATCCGAAGGATTTCACGCCGGTATGCACGACCGAGCTCGGCGCCCTCGCCC
GGCTGAAGCCCGAATTCGACAAGCGCGGCGTCAAGCTGCTGGGCCTCTCGGTCGATCCGGTGGACAAGCACGCGCAGTGG
TCCGAAGACATCCGCGAGACCCAGGGTGCGGCGCCGAACTATCCGATGATCGGCGATACCGATTACAACGTCTCCAAGCT
CTACGACATGCTGCCGGCCGCCGTATCCGGCGATCCCGCCAAGCGCACCGCCGCCGACAATCTGACCGTCCGCAACGTGT
TCATCATCGGGCCCGACAAGAAGATCAAGCTGATCCTGGTCTATCCGATGACCACCGGCCGCAACTTCCAGGAAATTCTC
CGCGTCATCGACTCGCTGCAGCTCACCGCCAAGCACCGCGTCGCCACTCCCGCCGACTGGAAGCAGGGCGAGGACGTGAT
CATCGCGGGCTCCGTGTCCGACGACGAGGCCAAGACGATCTATCCCGACGGCTGGAAGGCCCCGAAGCCGTATCTGCGCG
TGGTGCCTCAGCCGAAGTAA

Upstream 100 bases:

>100_bases
ATGTTCTCTTTTTTTCGAAACGGTTCCCATGGTGGGCGGTATTTCCTATAATCAAGAGAACAATTTATGCCGCCCCTTCA
ATTCTTCACGTGAGGACATC

Downstream 100 bases:

>100_bases
AGGGCGTCACACAGGGCTTGCAAAGGTTATCCCGGGACACCTCGCATAGGCGGACCCGGGATCTTGAGATTCGGGTTCGC
GCTGCGCGCGCCTCGGATTG

Product: thioredoxin peroxidase AhpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MALQIGSTAPDFEAETTEGKIKFHDWIGDSWALLFSHPKDFTPVCTTELGALARLKPEFDKRGVKLLGLSVDPVDKHAQW
SEDIRETQGAAPNYPMIGDTDYNVSKLYDMLPAAVSGDPAKRTAADNLTVRNVFIIGPDKKIKLILVYPMTTGRNFQEIL
RVIDSLQLTAKHRVATPADWKQGEDVIIAGSVSDDEAKTIYPDGWKAPKPYLRVVPQPK

Sequences:

>Translated_219_residues
MALQIGSTAPDFEAETTEGKIKFHDWIGDSWALLFSHPKDFTPVCTTELGALARLKPEFDKRGVKLLGLSVDPVDKHAQW
SEDIRETQGAAPNYPMIGDTDYNVSKLYDMLPAAVSGDPAKRTAADNLTVRNVFIIGPDKKIKLILVYPMTTGRNFQEIL
RVIDSLQLTAKHRVATPADWKQGEDVIIAGSVSDDEAKTIYPDGWKAPKPYLRVVPQPK
>Mature_218_residues
ALQIGSTAPDFEAETTEGKIKFHDWIGDSWALLFSHPKDFTPVCTTELGALARLKPEFDKRGVKLLGLSVDPVDKHAQWS
EDIRETQGAAPNYPMIGDTDYNVSKLYDMLPAAVSGDPAKRTAADNLTVRNVFIIGPDKKIKLILVYPMTTGRNFQEILR
VIDSLQLTAKHRVATPADWKQGEDVIIAGSVSDDEAKTIYPDGWKAPKPYLRVVPQPK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=227, Percent_Identity=50.6607929515419, Blast_Score=226, Evalue=1e-59,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=32.8042328042328, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=31.0526315789474, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=31.0526315789474, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=31.0526315789474, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI5453549, Length=170, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=29.0502793296089, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5802974, Length=151, Percent_Identity=29.1390728476821, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786822, Length=158, Percent_Identity=32.9113924050633, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=233, Percent_Identity=40.343347639485, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193204376, Length=197, Percent_Identity=29.4416243654822, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=29.8429319371728, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554494, Length=195, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319407, Length=213, Percent_Identity=55.3990610328638, Blast_Score=225, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581278, Length=226, Percent_Identity=48.6725663716814, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24652436, Length=207, Percent_Identity=48.792270531401, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24652434, Length=207, Percent_Identity=47.8260869565217, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI17975518, Length=207, Percent_Identity=47.8260869565217, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI17738015, Length=185, Percent_Identity=28.6486486486486, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=30.5882352941176, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=30.5882352941176, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357347, Length=199, Percent_Identity=28.1407035175879, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24656348, Length=202, Percent_Identity=28.7128712871287, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864676, Length=202, Percent_Identity=28.7128712871287, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24275; Mature: 24144

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQIGSTAPDFEAETTEGKIKFHDWIGDSWALLFSHPKDFTPVCTTELGALARLKPEFD
CEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHH
KRGVKLLGLSVDPVDKHAQWSEDIRETQGAAPNYPMIGDTDYNVSKLYDMLPAAVSGDPA
CCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCH
KRTAADNLTVRNVFIIGPDKKIKLILVYPMTTGRNFQEILRVIDSLQLTAKHRVATPADW
HHHCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
KQGEDVIIAGSVSDDEAKTIYPDGWKAPKPYLRVVPQPK
CCCCCEEEECCCCCCCCCEECCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
ALQIGSTAPDFEAETTEGKIKFHDWIGDSWALLFSHPKDFTPVCTTELGALARLKPEFD
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHH
KRGVKLLGLSVDPVDKHAQWSEDIRETQGAAPNYPMIGDTDYNVSKLYDMLPAAVSGDPA
CCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCH
KRTAADNLTVRNVFIIGPDKKIKLILVYPMTTGRNFQEILRVIDSLQLTAKHRVATPADW
HHHCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
KQGEDVIIAGSVSDDEAKTIYPDGWKAPKPYLRVVPQPK
CCCCCEEEECCCCCCCCCEECCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]