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The map label for this gene is 146340211

Identifier: 146340211

GI number: 146340211

Start: 3429915

End: 3431567

Strand: Reverse

Name: 146340211

Synonym: BRADO3229

Alternate gene names: NA

Gene position: 3431567-3429915 (Counterclockwise)

Preceding gene: 146340212

Following gene: 146340210

Centisome position: 46.02

GC content: 67.82

Gene sequence:

>1653_bases
ATGAGCTCGCAAACCAGCCTGATCGACCTGCAGATCATGTGGCACCGGCTGATCGCCGTGGTCGAGGAGCAGGCGCAGGT
GCTGCTGCGCACCGCCTTCAGCCCGATCGTGCGGGAATGCGGCGACCTCTCAGCCGGCGTGTTCGACCTGAAGGGCCGCA
TGCTGGCGCAGGCGGTTACCGGCACGCCGGGCCACGTCAACTCGATGGCGGAGTCGGTGAAGCACTTCATCGCGCATTTC
CCGCTTCAGACGATGAAGCCCGGCGATGCCTACATCACCAACGATCCCTGGATGGGCACCGGCCATCTCAACGACTTCGT
CGTGACCACGCCATGCTTCAAGGACGGCAAGCCGGTCGCTTTGTTCTCCTGCACCAGCCATCTGATGGACATCGGCGGCA
TTGGCTTCGGCCCTGATGGCACCGACGTGTTCATGGAGGGCCTTTACATCCCGATGCTGAAGCTGATCGACCAGGGCGTC
GTCAACGAAACCTTGATGGCTGTCATCCGCGCCAACACGCGGCTGCCGGTCGACACCGAAGGCGACACCTACTCGCTCGC
CGCCTGCAACGACGTCGGCTGCCAGCGCCTGGTCGAGATGATGACGGAGTTCGGCATCGCCTCGCTCGACGAACTCGGCG
ACTATGTCTGCGACCGCTCGCGCGAGGCGGTGCTGGCCGAGATCGCCAAGCTGCCGAAGGGCACCTTCCGCAACGAGATG
GTGGTCGACGGCTATGATGCGCCGGTAACGCTCAAGGCCGCGCTGACGATCAGCGATGCCGGCATTCACGTCGATTTCGA
CGGCACGTCGACGGCCTCGAAGTTCGGCATCAACGTGCCGCTGTCCTACACGACAGCCTACACCGTGTTCGGCCTCGGCT
GCGTGGTGGCGTCCGCGATTCCCAACAATGCCGGCTCGCTGTCGCCGCTGACGGTCTCCGCGCCTTCGGGCGCGATCCTC
AACGCGCCAAAGCCCGCGCCGGTCGCCTCGCGCCACGTCATCGGCCAGATGCTGCCCGACGTCGTGTTCGGTTGCCTGCG
CCAGATCATTCCGGAGCGCGTGCCCGCCGAAGGCACCTCCTGCCTGTGGAATCTCAACGTCCGCGGCCAGACCCGCTCCG
GCGCCGGCGGCAATTACGGGTTCTCGATGGCGGTGACGTCGAACGGCGGCACCGGCGCGCGTTTCGACAAGGACGGGCTG
TCGGCGACGGCCTATCCGTCCGGCGTGCGCGGCACGCCTGTCGAGATCGCCGAGACGCAGACGCCGCTGATCTTCTGGCG
CAAGGAGCTGCGGCCGGATTCAGGCGGCGCCGGCCGCACCCGCGGCGGCCTCGGCCAGATCATCGAGGTCGGCAGCGGCG
TCGACGCGCCGTTCGACATCCTCGCCGCCTTCGACCGCATCGACCACCCGCCCCGCGGCCGCGACGGCGGCCACAATGGC
GAGGCCGGCTATGTCGGGCTCGCCTCGGGCAAGAAGCTGCGCGGCAAGGGCTTCCAGACCGTGCCGCCGGACGACCGGCT
GGTGGTGCTGACACCGGGCGGCGCCGGCATCGGCGATCCGCGCGAGCGCGCGGCAGCGCTGGTGCAAGGCGATGTCGAGA
GCGGGCTGGTGTCGGCGGAGAACGCGGCAGCGGTCTACGGTCGAGCACGATGA

Upstream 100 bases:

>100_bases
TGATCGCCGAGGACGAGACCTCGACCTTCATCTCCAACAGTTTCGACGCGCATATCGACGGTGCCGGCAGCATCGTCATG
GAACGGAAGGCGGCCTAACC

Downstream 100 bases:

>100_bases
TGAACGATCGTATGAGACGGCAGCTGAGGCCTCGCCCCGTTTGGGGCATCGCTCTCGCCGCACGCGCGGTGCACCCTCTC
CCCTTGTGGGAGAGGGTGGC

Product: Hydantoin utilization protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSSQTSLIDLQIMWHRLIAVVEEQAQVLLRTAFSPIVRECGDLSAGVFDLKGRMLAQAVTGTPGHVNSMAESVKHFIAHF
PLQTMKPGDAYITNDPWMGTGHLNDFVVTTPCFKDGKPVALFSCTSHLMDIGGIGFGPDGTDVFMEGLYIPMLKLIDQGV
VNETLMAVIRANTRLPVDTEGDTYSLAACNDVGCQRLVEMMTEFGIASLDELGDYVCDRSREAVLAEIAKLPKGTFRNEM
VVDGYDAPVTLKAALTISDAGIHVDFDGTSTASKFGINVPLSYTTAYTVFGLGCVVASAIPNNAGSLSPLTVSAPSGAIL
NAPKPAPVASRHVIGQMLPDVVFGCLRQIIPERVPAEGTSCLWNLNVRGQTRSGAGGNYGFSMAVTSNGGTGARFDKDGL
SATAYPSGVRGTPVEIAETQTPLIFWRKELRPDSGGAGRTRGGLGQIIEVGSGVDAPFDILAAFDRIDHPPRGRDGGHNG
EAGYVGLASGKKLRGKGFQTVPPDDRLVVLTPGGAGIGDPRERAAALVQGDVESGLVSAENAAAVYGRAR

Sequences:

>Translated_550_residues
MSSQTSLIDLQIMWHRLIAVVEEQAQVLLRTAFSPIVRECGDLSAGVFDLKGRMLAQAVTGTPGHVNSMAESVKHFIAHF
PLQTMKPGDAYITNDPWMGTGHLNDFVVTTPCFKDGKPVALFSCTSHLMDIGGIGFGPDGTDVFMEGLYIPMLKLIDQGV
VNETLMAVIRANTRLPVDTEGDTYSLAACNDVGCQRLVEMMTEFGIASLDELGDYVCDRSREAVLAEIAKLPKGTFRNEM
VVDGYDAPVTLKAALTISDAGIHVDFDGTSTASKFGINVPLSYTTAYTVFGLGCVVASAIPNNAGSLSPLTVSAPSGAIL
NAPKPAPVASRHVIGQMLPDVVFGCLRQIIPERVPAEGTSCLWNLNVRGQTRSGAGGNYGFSMAVTSNGGTGARFDKDGL
SATAYPSGVRGTPVEIAETQTPLIFWRKELRPDSGGAGRTRGGLGQIIEVGSGVDAPFDILAAFDRIDHPPRGRDGGHNG
EAGYVGLASGKKLRGKGFQTVPPDDRLVVLTPGGAGIGDPRERAAALVQGDVESGLVSAENAAAVYGRAR
>Mature_549_residues
SSQTSLIDLQIMWHRLIAVVEEQAQVLLRTAFSPIVRECGDLSAGVFDLKGRMLAQAVTGTPGHVNSMAESVKHFIAHFP
LQTMKPGDAYITNDPWMGTGHLNDFVVTTPCFKDGKPVALFSCTSHLMDIGGIGFGPDGTDVFMEGLYIPMLKLIDQGVV
NETLMAVIRANTRLPVDTEGDTYSLAACNDVGCQRLVEMMTEFGIASLDELGDYVCDRSREAVLAEIAKLPKGTFRNEMV
VDGYDAPVTLKAALTISDAGIHVDFDGTSTASKFGINVPLSYTTAYTVFGLGCVVASAIPNNAGSLSPLTVSAPSGAILN
APKPAPVASRHVIGQMLPDVVFGCLRQIIPERVPAEGTSCLWNLNVRGQTRSGAGGNYGFSMAVTSNGGTGARFDKDGLS
ATAYPSGVRGTPVEIAETQTPLIFWRKELRPDSGGAGRTRGGLGQIIEVGSGVDAPFDILAAFDRIDHPPRGRDGGHNGE
AGYVGLASGKKLRGKGFQTVPPDDRLVVLTPGGAGIGDPRERAAALVQGDVESGLVSAENAAAVYGRAR

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=551, Percent_Identity=30.4900181488203, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI133901900, Length=547, Percent_Identity=27.7879341864717, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI133901902, Length=506, Percent_Identity=27.6679841897233, Blast_Score=145, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6322634, Length=555, Percent_Identity=27.5675675675676, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45550492, Length=540, Percent_Identity=26.8518518518519, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: NA

Molecular weight: Translated: 57911; Mature: 57779

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQTSLIDLQIMWHRLIAVVEEQAQVLLRTAFSPIVRECGDLSAGVFDLKGRMLAQAVT
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GTPGHVNSMAESVKHFIAHFPLQTMKPGDAYITNDPWMGTGHLNDFVVTTPCFKDGKPVA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCEE
LFSCTSHLMDIGGIGFGPDGTDVFMEGLYIPMLKLIDQGVVNETLMAVIRANTRLPVDTE
EEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
GDTYSLAACNDVGCQRLVEMMTEFGIASLDELGDYVCDRSREAVLAEIAKLPKGTFRNEM
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCE
VVDGYDAPVTLKAALTISDAGIHVDFDGTSTASKFGINVPLSYTTAYTVFGLGCVVASAI
EEECCCCCEEEEEEEEEECCCEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
PNNAGSLSPLTVSAPSGAILNAPKPAPVASRHVIGQMLPDVVFGCLRQIIPERVPAEGTS
CCCCCCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
CLWNLNVRGQTRSGAGGNYGFSMAVTSNGGTGARFDKDGLSATAYPSGVRGTPVEIAETQ
EEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
TPLIFWRKELRPDSGGAGRTRGGLGQIIEVGSGVDAPFDILAAFDRIDHPPRGRDGGHNG
CCEEEEHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
EAGYVGLASGKKLRGKGFQTVPPDDRLVVLTPGGAGIGDPRERAAALVQGDVESGLVSAE
CCCEEECCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCHHHCCEECC
NAAAVYGRAR
CCCEECCCCC
>Mature Secondary Structure 
SSQTSLIDLQIMWHRLIAVVEEQAQVLLRTAFSPIVRECGDLSAGVFDLKGRMLAQAVT
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GTPGHVNSMAESVKHFIAHFPLQTMKPGDAYITNDPWMGTGHLNDFVVTTPCFKDGKPVA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCEE
LFSCTSHLMDIGGIGFGPDGTDVFMEGLYIPMLKLIDQGVVNETLMAVIRANTRLPVDTE
EEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
GDTYSLAACNDVGCQRLVEMMTEFGIASLDELGDYVCDRSREAVLAEIAKLPKGTFRNEM
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCE
VVDGYDAPVTLKAALTISDAGIHVDFDGTSTASKFGINVPLSYTTAYTVFGLGCVVASAI
EEECCCCCEEEEEEEEEECCCEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
PNNAGSLSPLTVSAPSGAILNAPKPAPVASRHVIGQMLPDVVFGCLRQIIPERVPAEGTS
CCCCCCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
CLWNLNVRGQTRSGAGGNYGFSMAVTSNGGTGARFDKDGLSATAYPSGVRGTPVEIAETQ
EEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
TPLIFWRKELRPDSGGAGRTRGGLGQIIEVGSGVDAPFDILAAFDRIDHPPRGRDGGHNG
CCEEEEHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
EAGYVGLASGKKLRGKGFQTVPPDDRLVVLTPGGAGIGDPRERAAALVQGDVESGLVSAE
CCCEEECCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCHHHCCEECC
NAAAVYGRAR
CCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]