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The map label for this gene is tlpC [H]

Identifier: 146340207

GI number: 146340207

Start: 3424507

End: 3426249

Strand: Direct

Name: tlpC [H]

Synonym: BRADO3225

Alternate gene names: 146340207

Gene position: 3424507-3426249 (Clockwise)

Preceding gene: 146340204

Following gene: 146340215

Centisome position: 45.93

GC content: 67.13

Gene sequence:

>1743_bases
TTGAGATTCAGTTGCAGTTCTCCAGGAAGGTTTTCTGACGTGTCCGTCAAATTGAAGCTCGGTACCAAGGCGCTGCTCGG
CGCCGTGGTCGTGATCGCGCTGAATACGGCCCTCGTGGTGGGCGCCGCCTACTGGTCCCTCACCAACGATTTTGCCGATC
GCGCCAAGCGCGACATCGAAGGCAATCTGCGCACCTTCGCCCTGACGTTCAACGAGACGTTCAAGGACGCCAAGGTCAGC
CTCCAGAACGGCGTCGTCACGCGCATCGAGGTCCCGGCGATCCCGGAGATCAAGGATCATGCGATCGTCGACCGCGCGGT
GTCGTATGTCGGCGGCAGCGCGACCCTGTTCGTGGTCGACGACAGCGGCCAGTTCGTGCGCCGTTCCACCAACGTGAAGA
AGGAGAATGGCGACCGCGCGGTGGGCACGCAACTCGCCGCCGATCATCCGGCGCAGGCGCTGTTGCGTCGTGGCGAGGCC
TATAAGGGGCCGGCCGTGCTGTTCGGCAAGCCGTTCATGACGGCCTATTTCCCGGTTACCAATCCCGCGGGCAAGGTGAT
CGGCATCCTCTATGTCGGCGTACCGATGGCTGAGCTCGACGCCATGCTGTCGCAGGCGATGCAGACGATGATCATCGCTG
CGGTCGTCGCGGCGCTTCTCGTGCTCGGGCTGACGATGCTGGCCGTGAGCCGCGTGACCAAGCCGCTGAGCGCTGTGACG
GAGGCGCTGACTGCCATCGCCGAAGGACGGGACCACGTCGACATCACGTCCGACGACCGTGGCGACGAGATCGGCGAGAT
TGCCCGCAGCCTTGTCGTGTTCCGCAGCGCCGCCAGCGAGCGGCGCCGGATGCGCGAGGAGCAGGCGGCGTCCACGATCG
CGGCGGTCGAGCACCGCAAGGCCGAGCTGCAGCGCTTCGTCGATTCCTTCCAGACCAGCATCGGCGGCATCATCGAGAAT
GTGCTGACCTCGTCGGGCGAGTTCGAGCGCGAGGCGCGCCAGCTGACACAGACCGCGCGCACCACAGCCGATCTCTCGGG
ACAGTCGGCCGGCGCCTCGGAGACCGCGTCGGAGCACGTCCGCACCGCCGCGGCGGCATCCGACGAGCTCTCCGGCTCGA
TCGCCGAGATCATCCGCCGCGTCCAAGAGTCCAACGCCATTGCCGCCGAGGCGGTCAAGCAGGCCACCGCCACCGACCAG
CGCATCAAGGAGCTGTCTGACGCAGGCAACCGCATCGGCGACGTCGTCAAGCTGATCACCTCGATCGCCGAGCAGACCAA
CCTGCTGGCGCTCAATGCCACCATCGAGGCGGCACGCGCCGGCGATGCCGGCCGCGGCTTCGCGGTCGTCGCCCAGGAGG
TCAAGACGCTCGCCGGGCAGACCGCCAAGGCCACCGAGGAGATCTCCAGCCAGATCGCCAACATGCAGACGGTGACGCAG
GAATCGGTCGACGCCATCAAGGCGATCGGCTCGACCATCGAGCGCATCAACGAGATTGCGGCGTCGATCTCGGCCGCGGT
CGAGCAGCAGCGCGCCGCCACGCAGAACATCACCCAGAGCGTCCGCTCGGCCGCGAGCGGCACCGCCGAGGTCGTCAACA
ACATCCGCAGCGCGGCGCGCGGGGCGGGCGAGACCGGCGAAAGCTCCAACCGGATGTTCGCCTCCGCCCAGGCGCTGTCC
GGCGAGAGCCTGCGCCTGAAGGCCGAGGTGCAGAAGTTCCTCGACGGGATGCGCGCGGCTTGA

Upstream 100 bases:

>100_bases
GGGGGGGGAGCCATTCTGAGGTATCTTATTGCTGTTTTTCCGGTGATGTCAGTATTCTTCCGGCCGGAAAATAATCTGAT
GGAAACCAAATACGGGCACT

Downstream 100 bases:

>100_bases
TTTGCCCGGCCGGATGGCGCTGACACCCATCCGAACCCTCGCTCTCTCGTCATTCCGGGGCGCGCGAAGCGCGAGCCCGG
AATCCATAACCACGAGCGGT

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MRFSCSSPGRFSDVSVKLKLGTKALLGAVVVIALNTALVVGAAYWSLTNDFADRAKRDIEGNLRTFALTFNETFKDAKVS
LQNGVVTRIEVPAIPEIKDHAIVDRAVSYVGGSATLFVVDDSGQFVRRSTNVKKENGDRAVGTQLAADHPAQALLRRGEA
YKGPAVLFGKPFMTAYFPVTNPAGKVIGILYVGVPMAELDAMLSQAMQTMIIAAVVAALLVLGLTMLAVSRVTKPLSAVT
EALTAIAEGRDHVDITSDDRGDEIGEIARSLVVFRSAASERRRMREEQAASTIAAVEHRKAELQRFVDSFQTSIGGIIEN
VLTSSGEFEREARQLTQTARTTADLSGQSAGASETASEHVRTAAAASDELSGSIAEIIRRVQESNAIAAEAVKQATATDQ
RIKELSDAGNRIGDVVKLITSIAEQTNLLALNATIEAARAGDAGRGFAVVAQEVKTLAGQTAKATEEISSQIANMQTVTQ
ESVDAIKAIGSTIERINEIAASISAAVEQQRAATQNITQSVRSAASGTAEVVNNIRSAARGAGETGESSNRMFASAQALS
GESLRLKAEVQKFLDGMRAA

Sequences:

>Translated_580_residues
MRFSCSSPGRFSDVSVKLKLGTKALLGAVVVIALNTALVVGAAYWSLTNDFADRAKRDIEGNLRTFALTFNETFKDAKVS
LQNGVVTRIEVPAIPEIKDHAIVDRAVSYVGGSATLFVVDDSGQFVRRSTNVKKENGDRAVGTQLAADHPAQALLRRGEA
YKGPAVLFGKPFMTAYFPVTNPAGKVIGILYVGVPMAELDAMLSQAMQTMIIAAVVAALLVLGLTMLAVSRVTKPLSAVT
EALTAIAEGRDHVDITSDDRGDEIGEIARSLVVFRSAASERRRMREEQAASTIAAVEHRKAELQRFVDSFQTSIGGIIEN
VLTSSGEFEREARQLTQTARTTADLSGQSAGASETASEHVRTAAAASDELSGSIAEIIRRVQESNAIAAEAVKQATATDQ
RIKELSDAGNRIGDVVKLITSIAEQTNLLALNATIEAARAGDAGRGFAVVAQEVKTLAGQTAKATEEISSQIANMQTVTQ
ESVDAIKAIGSTIERINEIAASISAAVEQQRAATQNITQSVRSAASGTAEVVNNIRSAARGAGETGESSNRMFASAQALS
GESLRLKAEVQKFLDGMRAA
>Mature_580_residues
MRFSCSSPGRFSDVSVKLKLGTKALLGAVVVIALNTALVVGAAYWSLTNDFADRAKRDIEGNLRTFALTFNETFKDAKVS
LQNGVVTRIEVPAIPEIKDHAIVDRAVSYVGGSATLFVVDDSGQFVRRSTNVKKENGDRAVGTQLAADHPAQALLRRGEA
YKGPAVLFGKPFMTAYFPVTNPAGKVIGILYVGVPMAELDAMLSQAMQTMIIAAVVAALLVLGLTMLAVSRVTKPLSAVT
EALTAIAEGRDHVDITSDDRGDEIGEIARSLVVFRSAASERRRMREEQAASTIAAVEHRKAELQRFVDSFQTSIGGIIEN
VLTSSGEFEREARQLTQTARTTADLSGQSAGASETASEHVRTAAAASDELSGSIAEIIRRVQESNAIAAEAVKQATATDQ
RIKELSDAGNRIGDVVKLITSIAEQTNLLALNATIEAARAGDAGRGFAVVAQEVKTLAGQTAKATEEISSQIANMQTVTQ
ESVDAIKAIGSTIERINEIAASISAAVEQQRAATQNITQSVRSAASGTAEVVNNIRSAARGAGETGESSNRMFASAQALS
GESLRLKAEVQKFLDGMRAA

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=528, Percent_Identity=26.1363636363636, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788194, Length=214, Percent_Identity=32.7102803738318, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI2367378, Length=333, Percent_Identity=25.2252252252252, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789453, Length=415, Percent_Identity=26.2650602409639, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788195, Length=116, Percent_Identity=37.9310344827586, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61282; Mature: 61282

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSCSSPGRFSDVSVKLKLGTKALLGAVVVIALNTALVVGAAYWSLTNDFADRAKRDIE
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNLRTFALTFNETFKDAKVSLQNGVVTRIEVPAIPEIKDHAIVDRAVSYVGGSATLFVVD
CCCEEEEEEECHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
DSGQFVRRSTNVKKENGDRAVGTQLAADHPAQALLRRGEAYKGPAVLFGKPFMTAYFPVT
CCCHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCHHEEEECCC
NPAGKVIGILYVGVPMAELDAMLSQAMQTMIIAAVVAALLVLGLTMLAVSRVTKPLSAVT
CCCHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALTAIAEGRDHVDITSDDRGDEIGEIARSLVVFRSAASERRRMREEQAASTIAAVEHRK
HHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELQRFVDSFQTSIGGIIENVLTSSGEFEREARQLTQTARTTADLSGQSAGASETASEHV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RTAAAASDELSGSIAEIIRRVQESNAIAAEAVKQATATDQRIKELSDAGNRIGDVVKLIT
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIAEQTNLLALNATIEAARAGDAGRGFAVVAQEVKTLAGQTAKATEEISSQIANMQTVTQ
HHHHHCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESVDAIKAIGSTIERINEIAASISAAVEQQRAATQNITQSVRSAASGTAEVVNNIRSAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GAGETGESSNRMFASAQALSGESLRLKAEVQKFLDGMRAA
CCCCCCCCCCCEEHHHHHCCCCCEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFSCSSPGRFSDVSVKLKLGTKALLGAVVVIALNTALVVGAAYWSLTNDFADRAKRDIE
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNLRTFALTFNETFKDAKVSLQNGVVTRIEVPAIPEIKDHAIVDRAVSYVGGSATLFVVD
CCCEEEEEEECHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
DSGQFVRRSTNVKKENGDRAVGTQLAADHPAQALLRRGEAYKGPAVLFGKPFMTAYFPVT
CCCHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCHHEEEECCC
NPAGKVIGILYVGVPMAELDAMLSQAMQTMIIAAVVAALLVLGLTMLAVSRVTKPLSAVT
CCCHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALTAIAEGRDHVDITSDDRGDEIGEIARSLVVFRSAASERRRMREEQAASTIAAVEHRK
HHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELQRFVDSFQTSIGGIIENVLTSSGEFEREARQLTQTARTTADLSGQSAGASETASEHV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RTAAAASDELSGSIAEIIRRVQESNAIAAEAVKQATATDQRIKELSDAGNRIGDVVKLIT
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIAEQTNLLALNATIEAARAGDAGRGFAVVAQEVKTLAGQTAKATEEISSQIANMQTVTQ
HHHHHCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESVDAIKAIGSTIERINEIAASISAAVEQQRAATQNITQSVRSAASGTAEVVNNIRSAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GAGETGESSNRMFASAQALSGESLRLKAEVQKFLDGMRAA
CCCCCCCCCCCEEHHHHHCCCCCEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]