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The map label for this gene is gppA [H]

Identifier: 146340135

GI number: 146340135

Start: 3352030

End: 3352989

Strand: Direct

Name: gppA [H]

Synonym: BRADO3150

Alternate gene names: 146340135

Gene position: 3352030-3352989 (Clockwise)

Preceding gene: 146340133

Following gene: 146340136

Centisome position: 44.95

GC content: 68.44

Gene sequence:

>960_bases
GTGTATGCGGCCCTGGACCTTGGAACCAACAATTGCCGGCTCCTGATCGCCTGTCCCTCGGGCGACAGTTTCCGCGTGGT
CGACTCCTTCTCGCGCATCGTCCGGCTGGGCGAGGGCATCTCGACCACCGGCTGCATCAGCGACGCGGCGATGGACCGGG
CCATCGCGGCGCTGTCCATCTGCCGGGACAAGATCCAGTCGAAGAAGGCCAGGCGGCTGCGCCTGATCGCGACCGAGGCC
TGCCGCGCGGCGGCCAATGCCGAGGGGTTCCGGACCCGGGTGGCGGCGGAGACCGGCATCGAGCTCGAGGTGATCGACCG
CGAAACCGAAGCTGCGCTGGCCGTGAAGGGCTGTGCGCCGCTGCTCGACCCCGGCGGGCGCGGGGCGATCCTGTTCGACA
TCGGCGGCGGCTCCAGCGAACTGGTCCGGATCGAACGTGATCCGGCCGATCGCCATGCCGAGCCGCGCATCAAGGCCTGG
ATGTCGATTCCATTGGGCGTCGTGACGCTGGCCGAGCGGTTCGGCGGCCGCGACGTGACGCCGGAGATCTATGCGGCCAT
GGTCGAGGCGGTTGCGGAGCATGTCGGCCCGTTCGCGGCCGAGAACGGCGGCGATCTCGACCGCATGCATCTGCTCGGCA
CGTCGGGCACGGTGACGACGCTCGCGGGCATCCACCTCAACCTCGCGCGTTACGATCGCCGACGCGTCGACGGCATCTGG
ATCAACGATTCAGACATCACGTCGACGATCGGCAAGCTGTTGGCGATGAGCTATCAGGAGCGCGCCGAGAACAACTGCAT
CAGCATCGACCGTGCCGATCTCGTGCTGGCCGGCTGCGCCATTCTCGACGCCATCCGGCAATCCTTCCCGCTGCCGCGCC
TGCGCGTCGCCGATCGCGGCCTGCGCGAAGGCATGCTGGTCGAGATGATGCGCGAGGACGGCGCGCTGAGGTCGGCGTAG

Upstream 100 bases:

>100_bases
GCGGCTGCGGGAGAGTCCCACGCCGCGCGGGAACCTGGAGCCCGGCTTGAATCCGGGTCTGGACGTCGCGACACCGGCCT
GCGCCAGCCACGGCAGCAGC

Downstream 100 bases:

>100_bases
CAAAGGATTGACGACGTCATTCCGGGGCGGGCCGGACGAAAACAGCGAAGCTGTTTGCGTCTGGCGCGAACCGGGAAACT
CGTTCCGTAACCTCTGGATT

Product: putative exopolyphosphatase

Products: NA

Alternate protein names: Guanosine pentaphosphate phosphohydrolase; pppGpp-5'-phosphohydrolase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MYAALDLGTNNCRLLIACPSGDSFRVVDSFSRIVRLGEGISTTGCISDAAMDRAIAALSICRDKIQSKKARRLRLIATEA
CRAAANAEGFRTRVAAETGIELEVIDRETEAALAVKGCAPLLDPGGRGAILFDIGGGSSELVRIERDPADRHAEPRIKAW
MSIPLGVVTLAERFGGRDVTPEIYAAMVEAVAEHVGPFAAENGGDLDRMHLLGTSGTVTTLAGIHLNLARYDRRRVDGIW
INDSDITSTIGKLLAMSYQERAENNCISIDRADLVLAGCAILDAIRQSFPLPRLRVADRGLREGMLVEMMREDGALRSA

Sequences:

>Translated_319_residues
MYAALDLGTNNCRLLIACPSGDSFRVVDSFSRIVRLGEGISTTGCISDAAMDRAIAALSICRDKIQSKKARRLRLIATEA
CRAAANAEGFRTRVAAETGIELEVIDRETEAALAVKGCAPLLDPGGRGAILFDIGGGSSELVRIERDPADRHAEPRIKAW
MSIPLGVVTLAERFGGRDVTPEIYAAMVEAVAEHVGPFAAENGGDLDRMHLLGTSGTVTTLAGIHLNLARYDRRRVDGIW
INDSDITSTIGKLLAMSYQERAENNCISIDRADLVLAGCAILDAIRQSFPLPRLRVADRGLREGMLVEMMREDGALRSA
>Mature_319_residues
MYAALDLGTNNCRLLIACPSGDSFRVVDSFSRIVRLGEGISTTGCISDAAMDRAIAALSICRDKIQSKKARRLRLIATEA
CRAAANAEGFRTRVAAETGIELEVIDRETEAALAVKGCAPLLDPGGRGAILFDIGGGSSELVRIERDPADRHAEPRIKAW
MSIPLGVVTLAERFGGRDVTPEIYAAMVEAVAEHVGPFAAENGGDLDRMHLLGTSGTVTTLAGIHLNLARYDRRRVDGIW
INDSDITSTIGKLLAMSYQERAENNCISIDRADLVLAGCAILDAIRQSFPLPRLRVADRGLREGMLVEMMREDGALRSA

Specific function: Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in th

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family. GppA subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=316, Percent_Identity=27.8481012658228, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788848, Length=312, Percent_Identity=25.6410256410256, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.40 [H]

Molecular weight: Translated: 34364; Mature: 34364

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAALDLGTNNCRLLIACPSGDSFRVVDSFSRIVRLGEGISTTGCISDAAMDRAIAALSI
CEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
CRDKIQSKKARRLRLIATEACRAAANAEGFRTRVAAETGIELEVIDRETEAALAVKGCAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHHHCCCEEEEECCCCHHHEEECCCCC
LLDPGGRGAILFDIGGGSSELVRIERDPADRHAEPRIKAWMSIPLGVVTLAERFGGRDVT
CCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCC
PEIYAAMVEAVAEHVGPFAAENGGDLDRMHLLGTSGTVTTLAGIHLNLARYDRRRVDGIW
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHEEEHHHHHHHHCCEEE
INDSDITSTIGKLLAMSYQERAENNCISIDRADLVLAGCAILDAIRQSFPLPRLRVADRG
ECCCHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
LREGMLVEMMREDGALRSA
HHCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYAALDLGTNNCRLLIACPSGDSFRVVDSFSRIVRLGEGISTTGCISDAAMDRAIAALSI
CEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
CRDKIQSKKARRLRLIATEACRAAANAEGFRTRVAAETGIELEVIDRETEAALAVKGCAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHHHCCCEEEEECCCCHHHEEECCCCC
LLDPGGRGAILFDIGGGSSELVRIERDPADRHAEPRIKAWMSIPLGVVTLAERFGGRDVT
CCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCC
PEIYAAMVEAVAEHVGPFAAENGGDLDRMHLLGTSGTVTTLAGIHLNLARYDRRRVDGIW
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHEEEHHHHHHHHCCEEE
INDSDITSTIGKLLAMSYQERAENNCISIDRADLVLAGCAILDAIRQSFPLPRLRVADRG
ECCCHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
LREGMLVEMMREDGALRSA
HHCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA