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The map label for this gene is fadB1 [H]

Identifier: 146340124

GI number: 146340124

Start: 3337568

End: 3338620

Strand: Direct

Name: fadB1 [H]

Synonym: BRADO3139

Alternate gene names: 146340124

Gene position: 3337568-3338620 (Clockwise)

Preceding gene: 146340123

Following gene: 146340125

Centisome position: 44.76

GC content: 64.86

Gene sequence:

>1053_bases
TTGATCGTTCGCCGCGAGGGATCTGCGGGCATCATCCGGCTCAACCGGCCCAAGGCGATCAATGCGATGACGCTGGAGAT
GTCGATAGGGATCGACGCGGCGCTCGATCAGTTCGAAGCCGATCCCGCCATTGCCGTGGTCCTGCTGGAAGGCGCCGGCG
AGCGTGGGCTGTGCGCCGGCGGCGACATTCGCGGGCTCTATGAGAGCTCGAAGGTCAATGGCGATCTCGGCAAGGTGTTC
TGGCGCCAGGAATACATCATGAACGCGCGCATCGCCGCGTTCCCGAAGCCGTATGTCGCCTACATGGACGGCTTGGTGAT
GGGCGGCGGCGTCGGCCTCTCGGCGCATGGCCGGCACCGCATCGTCACCGAGAAGACCAGGCTTGCGATGCCCGAGGTCG
GCCTCGGCTTCTTCCCGGATGTCGGCGGCACCTGGCTGCTGTCGCGCGCGCCGGGCGAACTCGGCGCCTATTTCGGCCTG
ACCGGGCAGACCATGAACGGTCCCGACGCGATCCATGCCCGCTTTGCCGATGCCGTCGTGGCGACGTCGAACTGGCCGGC
GCTGCGCGAGGTCCTGACCAAGGTCAGGCCGGGGACATTGTCGGCGGAGATCGACCGCCTCATCGCCGGCTTTGCGACTG
GCGAAACTGAAGGACCGGTCGCCGCGCACCAGGCCAAGATCGATGCGTGGTTCGCTCACGACAGCATGCACGATGTTTTT
GCTGCGCTGGAAGCCGATGACTCCGATTTGGCCGCGTCGACCCTGAAGACACTGAAGGAGAAGTCGCCGCGCGGCATGGT
GGTGACGCTGAAACTGTTGCGGCTGGCACGCGGCGCGACGTCGTTGCAAGAGTGCCTGGTGCGTGAGTATCGTGCCGCGC
TCGAAGTATTCCGTAGCGACGATTTCCGCGAGGGTGTGCGCGCCGCGATCATCGACAAGGATCGCAATCCGAAATGGTCG
CCGCCGGATGTCGATCAGGTGACGCCGGAGATGTTGGCGCCGTATCTCGCCGAGAACGGCCCTGACGAGCTGACATTCCC
GCAAGCGAGATAA

Upstream 100 bases:

>100_bases
GGGTGCACCAGATCCTCGAGGGCACCAACGAGATCATGCGCCTGATCGTGTCGCGCAAGCTGATCGAGGCCGCGCGATGA
GCGACGCGGTCGAAGGCGAT

Downstream 100 bases:

>100_bases
CAAGCAGGTCGAGGGGAGACAACGAAGCATGGCAACGATCGCATTCATCGGCCTCGGCAACATGGGCGGCCCGATGGCCG
CCAATCTCGTCAAGGCCGGC

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIVRREGSAGIIRLNRPKAINAMTLEMSIGIDAALDQFEADPAIAVVLLEGAGERGLCAGGDIRGLYESSKVNGDLGKVF
WRQEYIMNARIAAFPKPYVAYMDGLVMGGGVGLSAHGRHRIVTEKTRLAMPEVGLGFFPDVGGTWLLSRAPGELGAYFGL
TGQTMNGPDAIHARFADAVVATSNWPALREVLTKVRPGTLSAEIDRLIAGFATGETEGPVAAHQAKIDAWFAHDSMHDVF
AALEADDSDLAASTLKTLKEKSPRGMVVTLKLLRLARGATSLQECLVREYRAALEVFRSDDFREGVRAAIIDKDRNPKWS
PPDVDQVTPEMLAPYLAENGPDELTFPQAR

Sequences:

>Translated_350_residues
MIVRREGSAGIIRLNRPKAINAMTLEMSIGIDAALDQFEADPAIAVVLLEGAGERGLCAGGDIRGLYESSKVNGDLGKVF
WRQEYIMNARIAAFPKPYVAYMDGLVMGGGVGLSAHGRHRIVTEKTRLAMPEVGLGFFPDVGGTWLLSRAPGELGAYFGL
TGQTMNGPDAIHARFADAVVATSNWPALREVLTKVRPGTLSAEIDRLIAGFATGETEGPVAAHQAKIDAWFAHDSMHDVF
AALEADDSDLAASTLKTLKEKSPRGMVVTLKLLRLARGATSLQECLVREYRAALEVFRSDDFREGVRAAIIDKDRNPKWS
PPDVDQVTPEMLAPYLAENGPDELTFPQAR
>Mature_350_residues
MIVRREGSAGIIRLNRPKAINAMTLEMSIGIDAALDQFEADPAIAVVLLEGAGERGLCAGGDIRGLYESSKVNGDLGKVF
WRQEYIMNARIAAFPKPYVAYMDGLVMGGGVGLSAHGRHRIVTEKTRLAMPEVGLGFFPDVGGTWLLSRAPGELGAYFGL
TGQTMNGPDAIHARFADAVVATSNWPALREVLTKVRPGTLSAEIDRLIAGFATGETEGPVAAHQAKIDAWFAHDSMHDVF
AALEADDSDLAASTLKTLKEKSPRGMVVTLKLLRLARGATSLQECLVREYRAALEVFRSDDFREGVRAAIIDKDRNPKWS
PPDVDQVTPEMLAPYLAENGPDELTFPQAR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=354, Percent_Identity=37.2881355932203, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI37594469, Length=301, Percent_Identity=35.8803986710963, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI194097323, Length=170, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1787659, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI221142681, Length=181, Percent_Identity=29.8342541436464, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787660, Length=161, Percent_Identity=34.1614906832298, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=344, Percent_Identity=37.7906976744186, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI25144157, Length=344, Percent_Identity=37.7906976744186, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17554946, Length=170, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=205, Percent_Identity=24.8780487804878, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=360, Percent_Identity=30.2777777777778, Blast_Score=152, Evalue=8e-38,
Organism=Drosophila melanogaster, GI28571730, Length=332, Percent_Identity=38.5542168674699, Blast_Score=237, Evalue=7e-63,
Organism=Drosophila melanogaster, GI28571729, Length=332, Percent_Identity=38.5542168674699, Blast_Score=237, Evalue=9e-63,
Organism=Drosophila melanogaster, GI20129971, Length=176, Percent_Identity=30.6818181818182, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653477, Length=176, Percent_Identity=30.6818181818182, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 37861; Mature: 37861

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRREGSAGIIRLNRPKAINAMTLEMSIGIDAALDQFEADPAIAVVLLEGAGERGLCAG
CEEEECCCCCEEEECCCCCCEEEEEEEECCCHHHHHHHCCCCEEEEEEEECCCCCCCCCC
GDIRGLYESSKVNGDLGKVFWRQEYIMNARIAAFPKPYVAYMDGLVMGGGVGLSAHGRHR
CCCCHHHHCCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHCCEEECCCCCCCCCCCEE
IVTEKTRLAMPEVGLGFFPDVGGTWLLSRAPGELGAYFGLTGQTMNGPDAIHARFADAVV
EEEHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHEECCCCCCCCCCHHHHHHHHHHEE
ATSNWPALREVLTKVRPGTLSAEIDRLIAGFATGETEGPVAAHQAKIDAWFAHDSMHDVF
ECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEECCHHHHHH
AALEADDSDLAASTLKTLKEKSPRGMVVTLKLLRLARGATSLQECLVREYRAALEVFRSD
HHHCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
DFREGVRAAIIDKDRNPKWSPPDVDQVTPEMLAPYLAENGPDELTFPQAR
CHHHCCEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIVRREGSAGIIRLNRPKAINAMTLEMSIGIDAALDQFEADPAIAVVLLEGAGERGLCAG
CEEEECCCCCEEEECCCCCCEEEEEEEECCCHHHHHHHCCCCEEEEEEEECCCCCCCCCC
GDIRGLYESSKVNGDLGKVFWRQEYIMNARIAAFPKPYVAYMDGLVMGGGVGLSAHGRHR
CCCCHHHHCCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHCCEEECCCCCCCCCCCEE
IVTEKTRLAMPEVGLGFFPDVGGTWLLSRAPGELGAYFGLTGQTMNGPDAIHARFADAVV
EEEHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHEECCCCCCCCCCHHHHHHHHHHEE
ATSNWPALREVLTKVRPGTLSAEIDRLIAGFATGETEGPVAAHQAKIDAWFAHDSMHDVF
ECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEECCHHHHHH
AALEADDSDLAASTLKTLKEKSPRGMVVTLKLLRLARGATSLQECLVREYRAALEVFRSD
HHHCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
DFREGVRAAIIDKDRNPKWSPPDVDQVTPEMLAPYLAENGPDELTFPQAR
CHHHCCEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]