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The map label for this gene is 146340112

Identifier: 146340112

GI number: 146340112

Start: 3323460

End: 3324596

Strand: Direct

Name: 146340112

Synonym: BRADO3127

Alternate gene names: NA

Gene position: 3323460-3324596 (Clockwise)

Preceding gene: 146340111

Following gene: 146340113

Centisome position: 44.57

GC content: 67.72

Gene sequence:

>1137_bases
ATGACGTACATCACCGGCACCGGTCTCACCTCGTTCGGCCGCCATGACGGCCGTTCCTCGCTCGATCTCATGAGCGTGGC
GGCGCAGCTTGCGCTCGACGACGCCGAACTGACGCGCCGCGACATCGACGGCATCCTCTGCGGCTACTCCACCGTATCGC
CGCACATCATGCTCGCGACCGTGTTCGCCGAACATTTCGGCATCACGCCATCCTATGCCCATGCCGTGCAGGTCGGCGGC
GCCACCGGGCTCGCTATGGTGATGCTCGCACATCACCTCGTCGAGGCCGGCGTGGTCAGACACATGCTCGTCGTCGCCGG
CGAGAACCGCCTGACCGGGCAGAGCCGCGACGCCTCGATCCAGGCCCTGGCGCAGGTCGGCAATCCCGACTACGAACTGC
CGCTGGGACCGACGATCCCCGCTTATTACGGTCTCGTCGCCTCGCGCTACATGCACGAGCATGGCGTGACCGAACAGGAT
CTCGCCGAGTTCGCCGTGCTGATGCGCAGGCATGCGCACGATCATCCCGGGGCCCAATTTCACGAGCGCATCACGGTCGC
CGACGTCATGGCCTCCAAGCCGGTGGCGAAGCCATTGAAGCTGCTCGACTGCTGCCCGGTCTCCGACGGCGGCGCTGCGA
TCATCGTCAGCCGCGAGCCGACCGCGGGGACCGCGGTGCGGGTGCGCGGCTGCGCCCAGGCCCATACCCACCAGCACGTA
ACCGCGGCGCCGGCTCTGAGCGGGCTCGGCGCCGAGATCGCGATCAGGCAGGCAAAGGCGGCCGCCAGCGTTGCGATCTC
CGACGTCCGCTATGCGGCGGTTTATGACAGCTTCACCATCACGCTCTGCATGCTGCTCGAAGACCTCGGCCTCGCGGGTC
GAGGGGAAGCGGCGGCGCAAGTGCGGGACGGCCATTTCAGCCGGGATGGCGCGGTACCCCTCAACACCCATGGCGGCCTG
TTGAGCTACGGCCATTGTGGTGTCGGCGGCGCGATGGCGCATCTCAACGAGGCACATCTGCAGATGACGGGGCGGGCCGG
AGCCCGTCAGGTGCGCGATGCCGCGCTGACGCTGCTGCATGGCGACGGCGGCGTGCTGTCCTCGCATGTCAGCATGTTCT
GGGAGCGGGAGCGATGA

Upstream 100 bases:

>100_bases
CCCGGAATCTCGAGATTGTTGTGCTCCATCATCCCACACCTCGAGATTTCCGGTTCATCGCTGCGCGACGCCCCGGAATG
ACGGCGAAGGGTGTAGTGCC

Downstream 100 bases:

>100_bases
ACGAATCAGCCGACTGGACGAAGGGCGCCGCGGCGACCGGCTATCAACGCTGCGCGTGCTGCGCCCATGTGCAGTACTTC
AGGCGCGATTTCTGCGCGGC

Product: putative thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTYITGTGLTSFGRHDGRSSLDLMSVAAQLALDDAELTRRDIDGILCGYSTVSPHIMLATVFAEHFGITPSYAHAVQVGG
ATGLAMVMLAHHLVEAGVVRHMLVVAGENRLTGQSRDASIQALAQVGNPDYELPLGPTIPAYYGLVASRYMHEHGVTEQD
LAEFAVLMRRHAHDHPGAQFHERITVADVMASKPVAKPLKLLDCCPVSDGGAAIIVSREPTAGTAVRVRGCAQAHTHQHV
TAAPALSGLGAEIAIRQAKAAASVAISDVRYAAVYDSFTITLCMLLEDLGLAGRGEAAAQVRDGHFSRDGAVPLNTHGGL
LSYGHCGVGGAMAHLNEAHLQMTGRAGARQVRDAALTLLHGDGGVLSSHVSMFWERER

Sequences:

>Translated_378_residues
MTYITGTGLTSFGRHDGRSSLDLMSVAAQLALDDAELTRRDIDGILCGYSTVSPHIMLATVFAEHFGITPSYAHAVQVGG
ATGLAMVMLAHHLVEAGVVRHMLVVAGENRLTGQSRDASIQALAQVGNPDYELPLGPTIPAYYGLVASRYMHEHGVTEQD
LAEFAVLMRRHAHDHPGAQFHERITVADVMASKPVAKPLKLLDCCPVSDGGAAIIVSREPTAGTAVRVRGCAQAHTHQHV
TAAPALSGLGAEIAIRQAKAAASVAISDVRYAAVYDSFTITLCMLLEDLGLAGRGEAAAQVRDGHFSRDGAVPLNTHGGL
LSYGHCGVGGAMAHLNEAHLQMTGRAGARQVRDAALTLLHGDGGVLSSHVSMFWERER
>Mature_377_residues
TYITGTGLTSFGRHDGRSSLDLMSVAAQLALDDAELTRRDIDGILCGYSTVSPHIMLATVFAEHFGITPSYAHAVQVGGA
TGLAMVMLAHHLVEAGVVRHMLVVAGENRLTGQSRDASIQALAQVGNPDYELPLGPTIPAYYGLVASRYMHEHGVTEQDL
AEFAVLMRRHAHDHPGAQFHERITVADVMASKPVAKPLKLLDCCPVSDGGAAIIVSREPTAGTAVRVRGCAQAHTHQHVT
AAPALSGLGAEIAIRQAKAAASVAISDVRYAAVYDSFTITLCMLLEDLGLAGRGEAAAQVRDGHFSRDGAVPLNTHGGLL
SYGHCGVGGAMAHLNEAHLQMTGRAGARQVRDAALTLLHGDGGVLSSHVSMFWERER

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=386, Percent_Identity=25.3886010362694, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI302344760, Length=305, Percent_Identity=25.9016393442623, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI302344767, Length=305, Percent_Identity=25.9016393442623, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI302344762, Length=380, Percent_Identity=24.2105263157895, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI55956775, Length=342, Percent_Identity=23.3918128654971, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=386, Percent_Identity=24.0932642487047, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19921506, Length=385, Percent_Identity=25.974025974026, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24585051, Length=385, Percent_Identity=25.974025974026, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 39894; Mature: 39763

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYITGTGLTSFGRHDGRSSLDLMSVAAQLALDDAELTRRDIDGILCGYSTVSPHIMLAT
CCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCEEEECCCCCCCHHHHHH
VFAEHFGITPSYAHAVQVGGATGLAMVMLAHHLVEAGVVRHMLVVAGENRLTGQSRDASI
HHHHHHCCCCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHH
QALAQVGNPDYELPLGPTIPAYYGLVASRYMHEHGVTEQDLAEFAVLMRRHAHDHPGAQF
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHH
HERITVADVMASKPVAKPLKLLDCCPVSDGGAAIIVSREPTAGTAVRVRGCAQAHTHQHV
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECHHHHHCCCCH
TAAPALSGLGAEIAIRQAKAAASVAISDVRYAAVYDSFTITLCMLLEDLGLAGRGEAAAQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VRDGHFSRDGAVPLNTHGGLLSYGHCGVGGAMAHLNEAHLQMTGRAGARQVRDAALTLLH
HCCCCCCCCCCCEECCCCCEEECCCCCCCHHHHHCCHHHEEECCCHHHHHHHHHHEEEEE
GDGGVLSSHVSMFWERER
CCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TYITGTGLTSFGRHDGRSSLDLMSVAAQLALDDAELTRRDIDGILCGYSTVSPHIMLAT
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCEEEECCCCCCCHHHHHH
VFAEHFGITPSYAHAVQVGGATGLAMVMLAHHLVEAGVVRHMLVVAGENRLTGQSRDASI
HHHHHHCCCCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHH
QALAQVGNPDYELPLGPTIPAYYGLVASRYMHEHGVTEQDLAEFAVLMRRHAHDHPGAQF
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHH
HERITVADVMASKPVAKPLKLLDCCPVSDGGAAIIVSREPTAGTAVRVRGCAQAHTHQHV
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECHHHHHCCCCH
TAAPALSGLGAEIAIRQAKAAASVAISDVRYAAVYDSFTITLCMLLEDLGLAGRGEAAAQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VRDGHFSRDGAVPLNTHGGLLSYGHCGVGGAMAHLNEAHLQMTGRAGARQVRDAALTLLH
HCCCCCCCCCCCEECCCCCEEECCCCCCCHHHHHCCHHHEEECCCHHHHHHHHHHEEEEE
GDGGVLSSHVSMFWERER
CCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]