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The map label for this gene is mtnN [C]

Identifier: 146339637

GI number: 146339637

Start: 2822474

End: 2823124

Strand: Direct

Name: mtnN [C]

Synonym: BRADO2630

Alternate gene names: 146339637

Gene position: 2822474-2823124 (Clockwise)

Preceding gene: 146339636

Following gene: 146339640

Centisome position: 37.85

GC content: 69.12

Gene sequence:

>651_bases
ATGGTCATCTGCAGCTCGAGCGATCCCAGGCAATTGCGCTCGCTGCTCACCGTGTTCGATCCGACCTCGATTCGTGGCGT
CGTCAGCTTCGGCGTCGCCGGTGGCCTCGATCCCAGCCTGAAGGCCGGCGACATCGTCGTCGCCACCGAGGTCACTGCCG
GCGACGCGCGCTGGCTGTCCGGCCTTTCTCTCCGCGAAGAACACATCGCCCGCGCGGCGCTGAAGAAGCGCCGCGTCGTC
CGCGGCGTGCTCGCCGGTGCCGAGGAGGTGGTGGTGGCGCAGGCCCGCAAGGCGGCGTTGCGCATGAAGACCGGCGCGGC
CGCCGTCGACATGGAGAGCCACATCGCCGCCGCCTATGCCGCTGAATACAACCTGCCGTTTGCCGCGCTGCGCGTCATCT
CCGATCCCGCGCATCGCACTTTGCCGTCGCTCGCCAAGGACGCGATCAAGCCGAACGGCGATATCGACCTGCCGATGATC
CTGCGCGGCATCGCTCGCAATCCGACCGTGCTGAGCGGCCTGGTGTCCACCGGAATCGAGTTCAACCGCGCCCTTCGCTC
GCTGCGCGGCGCCCGCGACCTTCTGCTGAGCGGCCTGCTCGCGGCCGAGCACTTCCTCGAGACCGAGACGCTGGCCGCCG
CCGAGGCGTGA

Upstream 100 bases:

>100_bases
GGGGGACGATACGTCCACGGATCGCCCGATTGATCCGCGGCCAATCTTGGTCGTGACGGGACTTGTGCAGGAGGCTCGCA
TCGCCGCTGGCCCGGGCATG

Downstream 100 bases:

>100_bases
GGCCGCGACTCGCGGGCGATCGCCTGGTTAGTTGGAGCGGAGGTCCTCCGCTTATTCAGCTTGATCCGTCACAGCGGCAC
AGCGAAGCAATCCAGGGTGG

Product: hypothetical protein

Products: Adenine; S-Ribosyl-L-homocysteine [C]

Alternate protein names: Nucleoside Phosphorylase

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MVICSSSDPRQLRSLLTVFDPTSIRGVVSFGVAGGLDPSLKAGDIVVATEVTAGDARWLSGLSLREEHIARAALKKRRVV
RGVLAGAEEVVVAQARKAALRMKTGAAAVDMESHIAAAYAAEYNLPFAALRVISDPAHRTLPSLAKDAIKPNGDIDLPMI
LRGIARNPTVLSGLVSTGIEFNRALRSLRGARDLLLSGLLAAEHFLETETLAAAEA

Sequences:

>Translated_216_residues
MVICSSSDPRQLRSLLTVFDPTSIRGVVSFGVAGGLDPSLKAGDIVVATEVTAGDARWLSGLSLREEHIARAALKKRRVV
RGVLAGAEEVVVAQARKAALRMKTGAAAVDMESHIAAAYAAEYNLPFAALRVISDPAHRTLPSLAKDAIKPNGDIDLPMI
LRGIARNPTVLSGLVSTGIEFNRALRSLRGARDLLLSGLLAAEHFLETETLAAAEA
>Mature_216_residues
MVICSSSDPRQLRSLLTVFDPTSIRGVVSFGVAGGLDPSLKAGDIVVATEVTAGDARWLSGLSLREEHIARAALKKRRVV
RGVLAGAEEVVVAQARKAALRMKTGAAAVDMESHIAAAYAAEYNLPFAALRVISDPAHRTLPSLAKDAIKPNGDIDLPMI
LRGIARNPTVLSGLVSTGIEFNRALRSLRGARDLLLSGLLAAEHFLETETLAAAEA

Specific function: Responsible For Cleavage Of The Glycosidic Bond In Both 5'-Methylthioadenosine (Mta) And S-Adenosylhomocysteine (Sah). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.2.16 [C]

Molecular weight: Translated: 22784; Mature: 22784

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVICSSSDPRQLRSLLTVFDPTSIRGVVSFGVAGGLDPSLKAGDIVVATEVTAGDARWLS
CEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHH
GLSLREEHIARAALKKRRVVRGVLAGAEEVVVAQARKAALRMKTGAAAVDMESHIAAAYA
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AEYNLPFAALRVISDPAHRTLPSLAKDAIKPNGDIDLPMILRGIARNPTVLSGLVSTGIE
HHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCHH
FNRALRSLRGARDLLLSGLLAAEHFLETETLAAAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVICSSSDPRQLRSLLTVFDPTSIRGVVSFGVAGGLDPSLKAGDIVVATEVTAGDARWLS
CEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHH
GLSLREEHIARAALKKRRVVRGVLAGAEEVVVAQARKAALRMKTGAAAVDMESHIAAAYA
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AEYNLPFAALRVISDPAHRTLPSLAKDAIKPNGDIDLPMILRGIARNPTVLSGLVSTGIE
HHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCHH
FNRALRSLRGARDLLLSGLLAAEHFLETETLAAAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 1.8 {5'-methylthioadenosine}} 0.0004 {5'-methylthioadenosine}} 0.00031 {5'-methylthioadenosine}} 3 {S-adenosylhomocysteine}} 0.0043 {S-adenosylhomocysteine}} [C]

Substrates: S-Adenosyl-L-homocysteine; H2O [C]

Specific reaction: S-Adenosyl-L-homocysteine + H2O --> Adenine + S-Ribosyl-L-homocysteine [C]

General reaction: N-Glycosyl bond hydrolysis [C]

Inhibitor: 5'-Chlor of ormycin; 5'-Ethyl thioadenosine; 5'-Methyl thi of ormycin; 5'-Methyl thioinosine; 5'-Methyl thiotubercidin; 5'-n-Propyl thioadenosine; Adenine; AMP; L-Methionine; N-2-Hydroxy ethyl piperazine-N'-2-ethanesulfonic acid; S-8-Aza-Adenosyl homocyst

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA