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The map label for this gene is ygbM [C]

Identifier: 146339561

GI number: 146339561

Start: 2725493

End: 2726245

Strand: Direct

Name: ygbM [C]

Synonym: BRADO2552

Alternate gene names: 146339561

Gene position: 2725493-2726245 (Clockwise)

Preceding gene: 146339560

Following gene: 146339562

Centisome position: 36.55

GC content: 63.75

Gene sequence:

>753_bases
ATGTTCACCGAGCATCCCTTCCTCGATCGCTTCGCGGCCGCCGCCAAGGCCGGCTTCACGGCGGTCGAATTCCTGTTTCC
CTACGATCATCCCGTCGAGGAGGTCGGCAAGCGCCTCCACGGCAATGGCCTGACGCAGGCGCTGTTCAACCTGCCGCCCG
GCAATTGGGACGCCGGCGAGAAGGGCTTTGCGGCGCTGCTCGAGCGCTTCGACGATCTCAAGGCGAGCCTCGAGACGGCG
CTGCCTTACGCGAAAGCAACCGGCGTGAAGCGACTGCACCTGATGGCTGGCATCGCCGATCGCCACGACGCGAAAGCCGT
TGAGGCCTACTACAAGTCGGTCGCCTGGGCGGCGGAGTTCTTCGCGCCGCACGGCCTCGACGTCGTGCTCGAGCCGATCA
ATCCGCGCAACGTGCCCGGCTACTTCCTCAACGATTTCGGCTTCGCCCGCGACCTGATCCGCGAGCTCAAGATTCCCAAT
CTCAAGCTACAGTTCGACATCTATCACTGCCAGATCATCCATGGCGACGTCACGATGCGGCTGCGCGAGATGATGGACAT
CACCGGCCACATCCAGATCGCCAGCATCCCATCGCGCAACGAGCCCGATGGAGAGGAGCTGAACTATCCGTTCCTGTTCG
CCGAGCTCGACCGGCTCGGCTATGCCGGCTTCGTCGGCTGCGAATACAATCCGCGCGGCCGGACCGAGGACGGGCTCGGC
TGGTTTGAGCCCTACAAGGGAGTGAAGCCGTGA

Upstream 100 bases:

>100_bases
CGCATGTATGCCCAGGTCACCGGCACCACGCTGCCCGGCTCATCCAAGTAACAGCACGAGTCCTCGCATCATGCCTCGTT
TCGCCGCCAATCTCTCGATG

Downstream 100 bases:

>100_bases
CCCTGAAGCTCGGCTGCATCGCCGACGACTACACCGGCGCCTCCGACCTCGCCAACACGCTGACCCGCGCCGGGTTGCGC
ACGGTGCAGACCATCGGCGT

Product: putative sugar isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MFTEHPFLDRFAAAAKAGFTAVEFLFPYDHPVEEVGKRLHGNGLTQALFNLPPGNWDAGEKGFAALLERFDDLKASLETA
LPYAKATGVKRLHLMAGIADRHDAKAVEAYYKSVAWAAEFFAPHGLDVVLEPINPRNVPGYFLNDFGFARDLIRELKIPN
LKLQFDIYHCQIIHGDVTMRLREMMDITGHIQIASIPSRNEPDGEELNYPFLFAELDRLGYAGFVGCEYNPRGRTEDGLG
WFEPYKGVKP

Sequences:

>Translated_250_residues
MFTEHPFLDRFAAAAKAGFTAVEFLFPYDHPVEEVGKRLHGNGLTQALFNLPPGNWDAGEKGFAALLERFDDLKASLETA
LPYAKATGVKRLHLMAGIADRHDAKAVEAYYKSVAWAAEFFAPHGLDVVLEPINPRNVPGYFLNDFGFARDLIRELKIPN
LKLQFDIYHCQIIHGDVTMRLREMMDITGHIQIASIPSRNEPDGEELNYPFLFAELDRLGYAGFVGCEYNPRGRTEDGLG
WFEPYKGVKP
>Mature_250_residues
MFTEHPFLDRFAAAAKAGFTAVEFLFPYDHPVEEVGKRLHGNGLTQALFNLPPGNWDAGEKGFAALLERFDDLKASLETA
LPYAKATGVKRLHLMAGIADRHDAKAVEAYYKSVAWAAEFFAPHGLDVVLEPINPRNVPGYFLNDFGFARDLIRELKIPN
LKLQFDIYHCQIIHGDVTMRLREMMDITGHIQIASIPSRNEPDGEELNYPFLFAELDRLGYAGFVGCEYNPRGRTEDGLG
WFEPYKGVKP

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=244, Percent_Identity=43.4426229508197, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI300068964, Length=225, Percent_Identity=42.2222222222222, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1789095, Length=248, Percent_Identity=43.5483870967742, Blast_Score=211, Evalue=3e-56,
Organism=Escherichia coli, GI1786718, Length=252, Percent_Identity=38.4920634920635, Blast_Score=187, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17552022, Length=232, Percent_Identity=40.0862068965517, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI17530883, Length=246, Percent_Identity=31.7073170731707, Blast_Score=134, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 28133; Mature: 28133

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTEHPFLDRFAAAAKAGFTAVEFLFPYDHPVEEVGKRLHGNGLTQALFNLPPGNWDAGE
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCH
KGFAALLERFDDLKASLETALPYAKATGVKRLHLMAGIADRHDAKAVEAYYKSVAWAAEF
HHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FAPHGLDVVLEPINPRNVPGYFLNDFGFARDLIRELKIPNLKLQFDIYHCQIIHGDVTMR
HCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECHHHHH
LREMMDITGHIQIASIPSRNEPDGEELNYPFLFAELDRLGYAGFVGCEYNPRGRTEDGLG
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCC
WFEPYKGVKP
CCCCCCCCCC
>Mature Secondary Structure
MFTEHPFLDRFAAAAKAGFTAVEFLFPYDHPVEEVGKRLHGNGLTQALFNLPPGNWDAGE
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCH
KGFAALLERFDDLKASLETALPYAKATGVKRLHLMAGIADRHDAKAVEAYYKSVAWAAEF
HHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FAPHGLDVVLEPINPRNVPGYFLNDFGFARDLIRELKIPNLKLQFDIYHCQIIHGDVTMR
HCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECHHHHH
LREMMDITGHIQIASIPSRNEPDGEELNYPFLFAELDRLGYAGFVGCEYNPRGRTEDGLG
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCC
WFEPYKGVKP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]